• Title/Summary/Keyword: Integration patterns

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Efficiency of Transgenesis by Using Sperm Mediated Gene Transfer on the Cultured Prepubertal Mouse Testicular Cells

  • Song, Sang-Jin;Cho, Jae-Won;Jun, Jin-Hyun;Byun, Hye-Kyung;Park, Yong-Seog;Chung, Kil-Saeng;Lee, Hoon-Taek
    • Proceedings of the KSAR Conference
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    • 2004.06a
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    • pp.213-213
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    • 2004
  • Exogeneous DNA can reproducibly be delivered by co-injected spermatozoa and this transgenesis method is very efficient protocol. But, mosaic patterns of transgenic embryos and offspring were shown frequently. Whole blastomere integration is important in transgenic animal economics. (omitted)

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The Effect of Solution Agitation on the Electroless Cu Deposition Within Nano-patterns (용액 교반이 미세 패턴 내 무전해 구리 도금에 미치는 영향)

  • Lee, Joo-Yul;Kim, Man;Kim, Deok-Jin
    • Journal of the Korean institute of surface engineering
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    • v.41 no.1
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    • pp.23-27
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    • 2008
  • The effect of solution agitation on the copper electroless deposition process of ULSI (ultra large scale integration) interconnections was investigated by using physical, electrochemical and electrical techniques. It was found that proper solution agitation was effective to obtain superconformal copper configuration within the trenches of $130{\sim}80nm$ width. The transition of open potential during electroless deposition process showed that solution agitation induced compact structure of copper deposits by suppressing mass transfer of cuprous ions toward substrate. Also, the specific resistivity of copper layers was lowered by increasing agitation speed, which made the deposited copper particles smaller. Considering both copper deposit configuration and electric property, around 500 rpm of solution agitation was the most suitable for the homogeneous electroless copper filling within the ultra-fine patterns.

A Study of Optimal Distribution of Gas Temperature in Directly-Fired Reheating Furnace (직접 가열식 가열로 내 최적 분위기온도 분포 해석에 관한 연구)

  • Jeong, Eui-Soo;Shim, Sung-Min;Kim, Young-Deuk;Kang, Deok-Hong;Kim, Woo-Seung
    • Proceedings of the KSME Conference
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    • 2008.11b
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    • pp.2122-2125
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    • 2008
  • Because the reheating furnace consumes a large amount of energy to heat up the slabs, it is very important to find an optimal temperature patterns in the furnace for energy saving as well as uniform target temperature at the exit of the furnace. In this study, the temperature profiles in the slab are determined by solving the transient one-dimensional heat conduction equation in conjunction with boundary conditions with total heat exchange factors. The optimal temperature patterns are obtained to minimize the fuel consumption with satisfying the predetermined constraint conditions. The design optimization is performed by using a genetic algorithm and the optimal results are validated with results obtained from the PIDO tool, called as P.I.A.n.O.

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The ISDF Framework: Towards Secure Software Development

  • Alkussayer, Abdulaziz;Allen, William H.
    • Journal of Information Processing Systems
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    • v.6 no.1
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    • pp.91-106
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    • 2010
  • The rapid growth of communication and globalization has changed the software engineering process. Security has become a crucial component of any software system. However, software developers often lack the knowledge and skills needed to develop secure software. Clearly, the creation of secure software requires more than simply mandating the use of a secure software development lifecycle; the components produced by each stage of the lifecycle must be correctly implemented for the resulting system to achieve its intended goals. This study demonstrates that a more effective approach to the development of secure software can result from the integration of carefully selected security patterns into appropriate stages of the software development lifecycle to ensure that security designs are correctly implemented. The goal of this study is to provide developers with an Integrated Security Development Framework (ISDF) that can assist them in building more secure software.

Deep Learning-Based Occupancy Detection and Visualization for Architecture and Urban Data - Towards Augmented Reality and GIS Integration for Improved Safety and Emergency Response Modeling - (건물 내 재실자 감지 및 시각화를 위한 딥러닝 모델 - 증강현실 및 GIS 통합을 통한 안전 및 비상 대응 개선모델 프로토타이핑 -)

  • Shin, Dongyoun
    • Journal of KIBIM
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    • v.13 no.2
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    • pp.29-36
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    • 2023
  • This study explores the potential of utilizing video-based data analysis and machine learning techniques to estimate the number of occupants within a building. The research methodology involves developing a sophisticated counting system capable of detecting and tracking individuals' entry and exit patterns. The proposed method demonstrates promising results in various scenarios; however, it also identifies the need for improvements in camera performance and external environmental conditions, such as lighting. The study emphasizes the significance of incorporating machine learning in architectural and urban planning applications, offering valuable insights for the field. In conclusion, the research calls for further investigation to address the limitations and enhance the system's accuracy, ultimately contributing to the development of a more robust and reliable solution for building occupancy estimation.

On the Numerical Evaluation of the Wave Patten of a Havelock Source

  • Dong-Kee,Lee
    • Bulletin of the Society of Naval Architects of Korea
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    • v.16 no.4
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    • pp.13-21
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    • 1979
  • A method of evaluating Kelvin wave pattern is presented in this paper. The mathematical manipulation of x-derivative of the Green function of the Havelock source by the use of contour integration on the complex plane has resulted in the expression that can be readily incorporated with computer program. The efficiency and accuracy that can be secured by the use of the present mathematical expressions seem to be excellent when suitable numerical quadratures are employed. The wave patterns for particular submergences of the singularity are presented.

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Integration Testing Approach using Usage Patterns of Global Variables

  • Hossain, Muhammad Iqbal;Shin, Youngsul;Lee, Woo Jin
    • Proceedings of the Korea Information Processing Society Conference
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    • 2012.04a
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    • pp.1213-1214
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    • 2012
  • Global variables can be read or modified by any part of the program, making it difficult to remember or reason about every possible use. Sometime it has tight couplings between some of other variables, and couplings between variables and functions. The main focus of this paper is to use call graph and the control flow analysis to design a model from where we generate the test cases for testing global variables.

Local tissue effects of various barrier membranes in a rat subcutaneous model

  • Naenni, Nadja;Lim, Hyun-Chang;Strauss, Franz-Josef;Jung, Ronald E.;Hammerle, Christoph H.F.;Thoma, Daniel S.
    • Journal of Periodontal and Implant Science
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    • v.50 no.5
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    • pp.327-339
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    • 2020
  • Purpose: The purpose of this study was to examine the local tissue reactions associated with 3 different poly(lactic-co-glycolic acid) (PLGA) prototype membranes and to compare them to the reactions associated with commercially available resorbable membranes in rats. Methods: Seven different membranes-3 synthetic PLGA prototypes (T1, T2, and T3) and 4 commercially available membranes (a PLGA membrane, a poly[lactic acid] membrane, a native collagen membrane, and a cross-linked collagen membrane)-were randomly inserted into 6 unconnected subcutaneous pouches in the backs of 42 rats. The animals were sacrificed at 4, 13, and 26 weeks. Descriptive histologic and histomorphometric assessments were performed to evaluate membrane degradation, visibility, tissue integration, tissue ingrowth, neovascularization, encapsulation, and inflammation. Means and standard deviations were calculated. Results: The histological analysis revealed complete integration and tissue ingrowth of PLGA prototype T1 at 26 weeks. In contrast, the T2 and T3 prototypes displayed slight to moderate integration and tissue ingrowth regardless of time point. The degradation patterns of the 3 synthetic prototypes were similar at 4 and 13 weeks, but differed at 26 weeks. T1 showed marked degradation at 26 weeks, whereas T2 and T3 displayed moderate degradation. Inflammatory cells were present in all 3 prototype membranes at all time points, and these membranes did not meaningfully differ from commercially available membranes with regard to the extent of inflammatory cell infiltration. Conclusions: The 3 PLGA prototypes, particularly T1, induced favorable tissue integration, exhibited a similar degradation rate to native collagen membranes, and elicited a similar inflammatory response to commercially available non-cross-linked resorbable membranes. The intensity of inflammation associated with degradable dental membranes appears to relate to their degradation kinetics, irrespective of their material composition.

Gain of New Exons and Promoters by Lineage-Specific Transposable Elements-Integration and Conservation Event on CHRM3 Gene

  • Huh, Jae-Won;Kim, Young-Hyun;Lee, Sang-Rae;Kim, Hyoungwoo;Kim, Dae-Soo;Kim, Heui-Soo;Kang, Han-Seok;Chang, Kyu-Tae
    • Molecules and Cells
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    • v.28 no.2
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    • pp.111-117
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    • 2009
  • The CHRM3 gene is a member of the muscarinic acetylcholine receptor family that plays important roles in the regulation of fundamental physiological functions. The evolutionary mechanism of exon-acquisition and alternative splicing of the CHRM3 gene in relation to transposable elements (TEs) were analyzed using experimental approaches and in silico analysis. Five different transcript variants (T1, T2, T3, T3-1, and T4) derived from three distinct promoter regions (T1: L1HS, T2, T4: original, T3, T3-1: THE1C) were identified. A placenta (T1) and testis (T3 and T3-1)-dominated expression pattern appeared to be controlled by different TEs (L1HS and THE1C) that were integrated into the common ancestor genome during primate evolution. Remarkably, the T1 transcript was formed by the integration event of the human specific L1HS element. Among the 12 different brain regions, the brain stem, olfactory region, and cerebellum showed decreased expression patterns. Evolutionary analysis of splicing sites and alternative splicing suggested that the exon-acquisition event was determined by a selection and conservation mechanism. Furthermore, continuous integration events of transposable elements could produce lineage specific alternative transcripts by providing novel promoters and splicing sites. Taken together, exon-acquisition and alternative splicing events of CHRM3 genes were shown to have occurred through the continuous integration of transposable elements following conservation.

Enhancing Smart Grid Efficiency through SAC Reinforcement Learning: Renewable Energy Integration and Optimal Demand Response in the CityLearn Environment (SAC 강화 학습을 통한 스마트 그리드 효율성 향상: CityLearn 환경에서 재생 에너지 통합 및 최적 수요 반응)

  • Esanov Alibek Rustamovich;Seung Je Seong;Chang-Gyoon Lim
    • The Journal of the Korea institute of electronic communication sciences
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    • v.19 no.1
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    • pp.93-104
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    • 2024
  • Demand response is a strategy that encourages customers to adjust their consumption patterns at times of peak demand with the aim to improve the reliability of the power grid and minimize expenses. The integration of renewable energy sources into smart grids poses significant challenges due to their intermittent and unpredictable nature. Demand response strategies, coupled with reinforcement learning techniques, have emerged as promising approaches to address these challenges and optimize grid operations where traditional methods fail to meet such kind of complex requirements. This research focuses on investigating the application of reinforcement learning algorithms in demand response for renewable energy integration. The objectives include optimizing demand-side flexibility, improving renewable energy utilization, and enhancing grid stability. The results emphasize the effectiveness of demand response strategies based on reinforcement learning in enhancing grid flexibility and facilitating the integration of renewable energy.