• 제목/요약/키워드: Integration

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The Effect of Motion Recognition Occupational Therapy on the Physical Self-efficacy, and Visual-motor Integration, Interactive Peer Play of Children with Neurodevelopmental Disorders (모션 인식 활용 작업치료가 신경발달장애 아동의 신체적 자기효능감 및 시각-운동통합 능력, 놀이기술에 미치는 영향)

  • Kim, Ko-Un;Oh, Hye-Won
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.1
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    • pp.119-128
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    • 2022
  • Purpose : The purpose of this study was to examine the effects of applying occupational therapy that uses motion recognition on the physical self-efficacy, visual-motor integration ability, and play skills of children who have neurodevelopmental disorder before and after treatment. Methods : This The study chose 16 children with neurodevelopmental disorder as research subjects who were randomly and evenly allocated into an experimental group and a control group. The experiment followed a pretest-posttest design. As an intervention, the experimental group received motion recognition-based occupational therapy and a separate sensory integration program. The control group only participated in the separate sensory integration program. The eight-week experiment duration included 24 intervention sessions where the a 50-minute session was implemented three times a week for eight weeks. To compare the physical self-efficacy, visual-motor integration ability, and play skills before and after the intervention, measurement tools including the Physical self efficacy, Beery VMI-6, and Penn interactive peer play scale were used. All measured variables were analyzed and expressed as mean, standard deviation and percentage. Results : The motion recognition-based occupational therapy demonstrated a significant effect on improving the physical self-efficacy, visual-motor integration ability, and play skills of the experimental group. The intervention also caused a significant difference between the experimental group and control group in terms of the physical self-efficacy, visual-motor integration ability, and play skills. Conclusion : We confirmed the possibility motion recognition-based occupational therapy could be effective in improving the physical self-efficacy, visual-motor integration ability, and play skills for patients who have neurodevelopmental disorder. Based on the study result, further future studies are expected based on this study result that prove the application effect of the motion recognition-based occupational therapy using disabled and non- disabled children as subjects are expected in the future.

Enhancement of β-1,3-Glucanase Activity by Sequential δ-Sequence Mediated Integration in Saccharomyces cerevisiae (출아효모에서 연속적 δ-sequence 삽입유도에 의한 β-1,3-glucanase 활성 증가)

  • Kim, Min-Jung;Kim, Yeon-Hee
    • Journal of Life Science
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    • v.24 no.10
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    • pp.1046-1054
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    • 2014
  • Beta-1,3-glucanase is widely used in various biotechnological and industrial processes, with over-production required to enable versatile utilization. We examined the overexpression of ${\beta}$-1,3-glucanase (EXGA) from Aspergillus oryzae using ${\delta}$-sequence-mediated integration. We constructed $pRS{\delta}$-exgA and $pRS{\delta}K$-exgA plasmids for integration of the EXGA gene into various chromosomes of Saccharomyces cerevisiae. These plasmids contain the ADH1 promoter for constitutive expression, a signal sequence (exoinulinase signal sequence [INU1 s.s]) for secretory production, and a ${\delta}$-sequence for integration of ${\beta}$-1,3-glucanase. The $pRS{\delta}$-exgA plasmid was transformed into the S. cerevisiae $BY4742{\Delta}exg1$ strain, and ${\beta}$-1.3-glucanase was stably overexpressed and secreted. Another plasmid, $pRS{\delta}K$-exgA, was introduced into the S. cerevisiae $BY4742{\Delta}exg1$ (YKY082) strain, and overexpression of ${\beta}$-1,3-glucanase was examined by inducible integration under geneticin selection. The activity of ${\beta}$-1,3-glucanase increased in accordance with a rise in the geneticin concentration, with 0.8 mg/ml of geneticin suitable for overexpression of ${\beta}$-1,3-glucanase. Subsequently, $pRS{\delta}K$-exgA was repeatedly transformed for sequential ${\delta}$-integration. The activity of ${\beta}$-1,3-glucanase reached about 0.063 unit/ml/$OD_{600}$, 0.095 unit/ml/$OD_{600}$, 0.131 unit/ml/$OD_{600}$ and 0.165 unit/ml/$OD_{600}$ by the first, second, third, and fourth round of integration, respectively. According to the increase in the activity of ${\beta}$-1,3-glucanase by sequential ${\delta}$-integration, the copy number (integration rate) of the EXGA gene also increased in various chromosomes. These results suggest that recombinant ${\beta}$-1,3-glucanase activity can be sequentially increased by repeated ${\delta}$-sequence integration.

Comparison of Methods for Stable Simultaneous Expression of Various Heterologous Genes in Saccharomyces cerevisiae (출아효모에서 다양한 이종 유전자의 안정적 동시발현을 위한 방법의 비교)

  • Jung, Heo-Myung;Kim, Yeon-Hee
    • Microbiology and Biotechnology Letters
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    • v.47 no.4
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    • pp.667-672
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    • 2019
  • We compared two integration systems for stable expression of heterologous genes in Saccharomyces cerevisiae. A Candida glabrata-derived gene was used as the selective marker for the Cre/loxP system, and XYLP, XYLB, GRE3, and XYL2 genes were used as model heterologous genes and ligated into the universal pRS-CMT vector. The resulting pRS-XylP, pRS-XylB, pRS-Gre3, and pRS-Xyl2 plasmids were sequentially integrated into yeast chromosome VII by four integration processes (marker rescue and gene integration). The four introduced genes were successfully expressed. Further, the pRS-PBG2 plasmid harboring expression cassettes for the four genes was constructed for one-step integration. The four genes that were introduced were stably maintained as a gene cluster and were simultaneously expressed. The one-step integration was more effective for the simultaneous integration and expression of the four genes related to xylan/xylose metabolism. This method will enable the generation of a useful biosystem through appropriate use of gene integration methods.

The Impact on Supply Chain Integration of Competitive Advantage on Information Communication Technology Capabilities (정보기술(ICT) 경쟁우위가 공급사슬통합에 미치는 영향)

  • Kim, Jeong-Hwan;Park, Chong-Suk
    • Journal of Korea Port Economic Association
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    • v.32 no.1
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    • pp.151-163
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    • 2016
  • This research analyzes the effect of the competitive edge in Information Communication Technology (ICT) on supply chain integration in business processes through a comparative analysis by industry that suggests a way of achieving competitive edge in ICT for effective supply chain integration. Based on the theoretical background, there are two research hypotheses. The first hypothesis is about the effect of a competitive edge in ICT on the supply chain. The second is that the effect of the competitive edge on supply chain integration varies from industry to industry. ICT infrastructure must be acquired in advance in order to attain a competitive edge in ICT to secure corporate competitiveness. Building a competitive edge in ICT itself by methods such as introduction, integration, and application, can directly improve company results. Therefore, it must be utilized strategically for improvement in standards of supply chain integration like information integration, organization integration, and strategy integration. If supply chain integration is accomplished effectively by gaining competitive edge in ICT, company results can be improved. By analyzing the effect of a company's competitive edge in ICT on supply chain integration, and comparing differences in features of each category of businesses, measures for developing a competitive edge in ICT and therefore supply chain integration are presented.

Research Trends in the Journal of Korean Academy of Sensory Integration from 2013 to 2022 (대한감각통합치료학회지의 연구동향: 2013~2022년)

  • Hong, Eunkyoung
    • The Journal of Korean Academy of Sensory Integration
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    • v.21 no.2
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    • pp.58-68
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    • 2023
  • Objective : This study aimed to analyze papers published in the Journal of Korean Academy of Sensory Integration over the past 10 years. Methods : This study analyzed 130 papers published in the Journal of Korean Academy of Sensory Integration from June 2013 to December 2022. The data analysis was performed by dividing the papers based on the researchers' region and affiliation, research type(s), level of evidence, participants, and field of research. Results : The researchers were mostly from the Gyeongsang-do region and universities. With regard to the type of research, descriptive research was the most common. Most studies were categorized as research level IV studies. Moreover, the number of level IV studies steadily increased on a year-by-year basis. Regarding the study participants, the studies most commonly concerned the diagnosis of attention deficit hyperactivity disorder. In terms of the field of study, the application of individual sensory integration therapy was most common, while the application of modified applications such as Ayres Sensory Integration® and remote sensory integration therapy programs was also noted. Conclusion : This study examined the recent research trends in the Journal of Korean Academy of Sensory Integration by analyzing the research type(s), level of evidence, participants, and field of research. The present results will help readers understand the research trends in the field of sensory integration therapy and pediatric intervention, and they will also contribute to the amount of evidence available.

A Petrov-Galerkin Natural Element Method Securing the Numerical Integration Accuracy

  • Cho Jin-Rae;Lee Hong-Woo
    • Journal of Mechanical Science and Technology
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    • v.20 no.1
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    • pp.94-109
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    • 2006
  • An improved meshfree method called the Petrov-Galerkin natural element (PG-NE) method is introduced in order to secure the numerical integration accuracy. As in the Bubnov-Galerkin natural element (BG-NE) method, we use Laplace interpolation function for the trial basis function and Delaunay triangles to define a regular integration background mesh. But, unlike the BG-NE method, the test basis function is differently chosen, based on the Petrov-Galerkin concept, such that its support coincides exactly with a regular integration region in background mesh. Illustrative numerical experiments verify that the present method successfully prevents the numerical accuracy deterioration stemming from the numerical integration error.

The Effects of Sensory Integration Therapy Camp in Children With Sensory Modulation Disorder : Case study (감각 조절 장애 아동에 대한 감각통합치료 캠프의 효과 - 사례보고)

  • Lee, Mi-Hee
    • The Journal of Korean Academy of Sensory Integration
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    • v.1 no.1
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    • pp.39-51
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    • 2003
  • Objective : To explore the effect of intensive sensory integration therapy through daily camp programs for children with sensory modulation disorder. Methods : A comparison of quantitative data and qualitative description between before and after sensory integration therapy camp and main outcome measure was used, including MAP behavior checklist, JSI-2, COPM, sensory history, STEP-SI. Results : The adaptive response was increased and sensory modulation problems were observed less than before the camp. Conclusion : For this study a more diverse, extended and intensive SI program is considered necessary. Further study is needed to develop these findings.

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Numerical Integration of Non-linear Equation of Motion using Operation of Integration (적분행렬을 이용한 비선형 운동방정식 수치적분)

  • Lee, Donghun;Kwon, Jae-Wook;Choi, Sujin;Rew, Dong-Young;Ju, Gwanghyeok
    • Aerospace Engineering and Technology
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    • v.13 no.2
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    • pp.60-65
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    • 2014
  • In this paper, numerical integration method using operational matrix of integration is studied. Using the operational matrix of integration, modified fixed point iteration method is introduced in order to solve rapidly an initial value problem for non-linear equation of motion. As an example, an initial value problem for orbital motion is considered. Through the numerical example, it is shown that the algorithm is efficient from the computational time point of view.

Real-time Fault Detection Method for an AGPS/INS Integration System

  • Oh, Sang-Heon;Yoon, Young-Seok;Hwang, Dong-Hwan
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.974-977
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    • 2003
  • The GPS/INS integration system navigation can provide improved navigation performance and has been widely used as a main navigation system for military and commercial vehicles. When two navigation systems are tightly coupled and the structure is complicated, a fault in either the GPS or the INS can lead to a disastrous failure of the whole integration system. This paper proposes a real-time fault detection method for an AGPS/INS integration system. The proposed fault detection method comprises a BIT and a fault detection algorithm based on chi-square test. It is implemented by real-time software modules to apply the AGPS/INS integration system and van test is carried out to evaluate its performance.

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Sensory Integration Therapy in Child with Sensory Modulation Disorder: Case Study (감각조절장애 아동에 대한 감각통합 치료적용-사례보고)

  • Kim, Mi-Hye;Ji, Seok-Yeon
    • The Journal of Korean Academy of Sensory Integration
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    • v.4 no.1
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    • pp.29-36
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    • 2006
  • Objective : To summarize and interpret observations of responses of child with sensory modulation disorder during four therapy sessions in order to contribute to future studies. Method : Analyze treatment goals and strengths and weaknesses of four therapy sessions and discuss implications of therapy. Results : Child's adaptive responses were improved throughout the therapy sessions. Conclusions : Intensive sensory integration therapy is needed continuously. Future study with this participant is needed to explore more effectiveness of sensory integration therapy.

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