• Structural Engineering and Mechanics
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• 제51권4호
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• pp.651-662
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• 2014

The main goal of this study is to extend the domain of influence result to cover the micropolar thermoelastic diffusion. So, we prove that for a finite time t>0 the displacement field $u_i$, the microrotation vector ${\varphi}_i$, the temperature ${\theta}$ and the chemical potential P generate no disturbance outside a bounded domain $B_t$.

• Molecules and Cells
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• 제24권2호
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• pp.240-246
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• 2007

The ${\beta}2$ integrins on leukocytes play important roles in cell adhesion, migration and phagocytosis. One of the ${\beta}2$ integrins, ${\alpha}X{\beta}2$ (CD11c/CD18), is known to bind ligands such as fibrinogen, Thy-1 and iC3b, but its function is not well characterized. To understand its biological roles, we attempted to identify novel ligands. The functional moiety of ${\alpha}X{\beta}2$, the ${\alpha}X$ I-domain, was found to bind plasminogen, the zymogen of plasmin, with moderate affinity ($1.92{\times}10^{-6}M$) in the presence of $Mg^{2+}$ or $Mn^{2+}$. The ${\beta}D-{\alpha}5$ loop of the ${\alpha}X$ I-domain proved to be responsible for binding, and lysine residues ($Lys^{242}$, $Lys^{243}$) in the loop were the most important for recognizing plasminogen. An excess amount of the lysine analog, 6-aminohexanoic acid, inhibited ${\alpha}X$ I-domain binding to plasminogen, indicating that binding is lysine-dependent. The results of this study indicate that leukocytes regulate plasminogen activation, and consequently plasmin activities, through an interaction with ${\alpha}X{\beta}2$ integrin.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 1998년도 학술발표회
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• pp.12-12
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• 1998

The interaction between the N-terminal domain of enzyme I (EIN) and the histidine-containing phosphocarrier protein HPr of the Escherichia coli phosphoenolpyruvate：sugar phosphotransferase system has been investigated by Isothermal Titration Calorimetry and heteronuclear magnetic resonance spectroscopy.(omitted)

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 합동 추계학술대회 논문집 정보 및 제어부문
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• pp.46-49
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• 2002

This paper presents I-PD controller design using LQR method in a two-inerita motor system to satisfy the design specification in time domain. And to provide a systematic LQ analysis for two-inerita motor system. The tuning parameters of LQ(I-PD) controller are determinated by the relationships between the design parameters of the overshoot and the settling time which are design specifications in time domain, and the weighting factors Q and R in LQR we can achieve the performance-robustness in time domain as well as the stability-robustness.

• 방송공학회논문지
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• 제27권4호
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• pp.511-518
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• 2022

딥러닝 기반의 지도학습은 다양한 응용 분야에서 비약적인 발전을 이루었다. 그러나 많은 지도 학습 방법들은 학습 및 테스트 데이터가 동일한 분포에서 추출된다는 공통된 가정 하에 이루어진다. 이 제약 조건에서 벗어나는 경우, 학습 도메인에서 훈련된 딥러닝 네트워크는 도메인 간의 분포 차이로 인하여 테스트 도메인에서의 성능이 급격하게 저하될 가능성이 높다. 도메인 적응 기술은 레이블이 풍부한 학습 도메인 (소스 도메인)의 학습된 지식을 기반으로 레이블이 불충분한 테스트 도메인 (타겟 도메인) 에서 성공적인 추론을 할 수 있도록 딥러닝 네트워크를 훈련하는 전이 학습의 한 방법론이다. 특히 비지도 도메인 적응 기술은 타겟 도메인에 레이블이 전혀 없는 이미지 데이터에만 접근할 수 있는 상황을 가정하여 도메인 적응 문제를 다룬다. 본 논문에서는 이러한 비지도 학습 기반의 도메인 적응 기술들에 대해 탐구한다.

• Journal of Microbiology and Biotechnology
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• 제19권2호
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• pp.121-127
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• 2009

Sequencing analysis of a 5-kb DNA fragment from Streptomyces venezuelae ATCC 15439 revealed the presence of one 3.1-kb open reading frame(ORF), designated as afsR-sv. The deduced product of afsR-sv(1,056 aa) was found to have high homology with the global regulatory protein AfsR. Homology-based analysis showed that aftR-sv represents a transcriptional activator belonging to the Streptomyces antibiotic regulatory protein(SARP) family that includes an N-terminal SARP domain containing a bacterial transcriptional activation domain(BTAD), an NB-ARC domain, and a C-terminal tetratricopeptide repeat domain. Gene expression analysis by reverse transcriptase PCR(RT-PCR) demonstrated the activation of transcription of genes belonging to pikromycin production, when aftR-sv was overexpressed in S. venezuelae. Heterologous expression of the aftR-sv in different Streptomyces strains resulted in increased production of the respective antibiotics, suggesting that afsR-sv is a positive regulator of antibiotics biosynthesis.

• 대한수학회보
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• 제48권6호
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• pp.1137-1146
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• 2011

Let {$X_i$, $i{\geq}1$} be a sequence of i.i.d. nondegenerate random variables which is in the domain of attraction of the normal law with mean zero and possibly infinite variance. Denote $S_n={\sum}_{i=1}^n\;X_i$, $M_n=max_{1{\leq}i{\leq}n}\;{\mid}S_i{\mid}$ and $V_n^2={\sum}_{i=1}^n\;X_i^2$. Then for d > -1, we showed that under some regularity conditions, $$\lim_{{\varepsilon}{\searrow}0}{\varepsilon}^2^{d+1}\sum_{n=1}^{\infty}\frac{(loglogn)^d}{nlogn}I\{M_n/V_n{\geq}\sqrt{2loglogn}({\varepsilon}+{\alpha}_n)\}=\frac{2}{\sqrt{\pi}(1+d)}{\Gamma}(d+3/2)\sum_{k=0}^{\infty}\frac{(-1)^k}{(2k+1)^{2d+2}}\;a.s.$$ holds in this paper, where If g denotes the indicator function.

• 대한전기학회논문지:전력기술부문A
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• 제52권11호
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• pp.632-638
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• 2003

Modern power systems are very complex and to model them completely is impractical for electromagnetic transient studies. Therefore areas outside the immediate area of interest must be represented by some form of frequency dependent equivalent. The s-domain rational function form of frequency dependent equivalent does not need refitting if the simulation time-step is changed in the electromagnetic transient program. This is because the s-domain rational function coefficients are independent of the simulation time-step, unlike the z-domain rational function coefficients. S-domain rational function fitting techniques for representing frequency dependent equivalents have been developed using Least Squares Fitting(LSF). However it does not suffer the implementation error that exited in this work as it ignored the instantaneous term. This paper Presents the formulation for developing 1 Port Frequency Dependent Network Equivalent(FDNE) with the instantaneous term in S-domain and illustrates its use. This 1 port FDNE have been applied to the CIGRE Benchmark Rectifier test AC system. The electromagnetic transient package PSCAD/EMTDC is used to assess the transient response of the 1 port (FDNE) developed with Thevenin and Norton Equivalent network. The study results have indicated the robustness and accuracy of 1 port FDNE for electromagnetic transient studies.

• Molecules and Cells
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• 제37권4호
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• pp.307-313
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• 2014

Cell migration requires a defined cell polarity which is formed by diverse cytoskeletal components differentially localized to the poles of cells to extracellular signals. Rap-GAP3 transiently and rapidly translocates to the cell cortex in response to chemoattractant stimulation and localizes to the leading edge of migrating cells. Here, we examined localization of truncated RapGAP3 proteins and found that the I/LWEQ domain in the central region of RapGAP3 was sufficient for posterior localization in migrating cells, as opposed to leading-edge localization of full-length Rap-GAP3. All truncated proteins accumulated at the leading edge of migrating cells exhibited clear translocation to the cell cortex in response to stimulation, whereas proteins localized to the posterior in migrating cells displayed no translocation to the cortex. The I/LWEQ domain appears to passively accumulate at the posterior region in migrating cells due to exclusion from the extended front region in response to chemoattractant stimulation rather than actively being localized to the back of cells. Our results suggest that posterior localization of the I/LWEQ domain of RapGAP3 is likely related to F-actin, which has probably different properties compared to newly formed F-actin at the leading edge of migrating cells, at the lateral and posterior regions of the cell.

• 말소리와 음성과학
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• 제3권4호
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• pp.13-21
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• 2011

The present study investigated the effects of two different sources of prosodic strengthening, i.e., boundary and accent, in the articulation of English high front vowels, /i/ and /I/. The vowels were investigated in vowel-initial ('eat' vs. 'it'), /h/-initial ('heat' vs. 'hit') and /p/-initial words ('Pete' vs. 'pit'), which were placed in varying prosodic conditions. Using Electromagnetic Articulograph (EMA), the tongue dorsum positions in the x and y dimensions, the lip opening and the jaw opening (lowering) were measured. With respect to the boundary-induced strengthening, results showed that /i/ and /I/ in vowel-initial words ('eat' - 'it') are produced with a higher tongue position in the domain-intial than domain-medial positions. The fact that the vowels only in the vowel-initial condition showed the domain-intial strengthening (DIS) effect suggests that the DIS effect is localized mainly to the initial position (the locality account). As for the accent-induced strengthening, vowels were produced with a more fronted tongue position and larger lip opening in accented than unaccented positions. This suggests that the presence of accent increases overall sonority of the vowels in various prosodic contexts, and enhances primarily the frontedness of the front high vowels. Taken together, the results indicate that the two types of prosodic strengthening are articulatorily realized differently, supporting the view that they are encoded separately in the speech planning process. The present study also showed the distinction between the two high front vowels in the tongue position (in both the frontedness and the height dimensions), while the jaw did not seem to contribute to the distinction robustly, suggesting that the tongue contributes more in distinguishing the two vowels than the jaw does.