• Journal of Powder Materials
• /
• v.21 no.4
• /
• pp.271-276
• /
• 2014

15Cr-1Mo base oxide dispersion strengthened (ODS) steel which is considered to be as a promising candidate for high- temperature components in nuclear fusion and fission systems because of its excellent high temperature strength, corrosion and radiation resistance was fabricated by using mechanical alloying, hot isostatic pressing and hot rolling. Torsion tests were performed at room temperature, leading to two different shear strain routes in the forward and reverse directions. In this study, microstructure evolution of the ODS steel during simple shearing was investigated. Fine grained microstructure and a cell structure of dislocation with low angle boundaries were characterized with shear strain in the shear deformed region by electron backscattered diffraction (EBSD). Grain refinement with shear strain resulted in an increase in hardness. After the forward-reverse torsion, the hardness value was measured to be higher than that of the forward torsion only with an identical shear strain amount, suggesting that new dislocation cell structures inside the grain were generated, thus resulting in a larger strengthening of the steel.

• 한국신재생에너지학회:학술대회논문집
• /
• 2011.05a
• /
• pp.87.1-87.1
• /
• 2011

The residential Fuel Cell system has high efficiency of 85% with transferring natural gas to electrical power and heat, directly and it is a friendly environmental new technology in that $CO_2$ emission can reduce 40% compared with conventional power generator and boiler. The residential fuel cell system consists of two main parts which have electrical and hot storage units. The electrical unit contains a fuel processor, a stack, an inverter, a control unit and balance of plant(BOP), and the cogeneration unit has heat exchanger, hot water tank, and auxiliaries. 5kW class fuel process was developed and tested from 2009, it was evaluated for long-term durability and reliability test including with improvement in optimal operation logic. Stack development was crried out through improvement of design and evaluation protocol. Development of system controller was successfully accomplished through strenuous efforts and original control logic was optimized in 5kW class PEMFC system. In addition, we have been focused on development of system process and assembly technology, which bring about excellent improvement of reliability of system. The 5kW class PEMFC system was operated under dynamic conditions for 1,000 hours and it showed a good performance of total efficiency and durability.

• Journal of Sasang Constitutional Medicine
• /
• v.24 no.1
• /
• pp.54-65
• /
• 2012

1. Objective : The purpose of this study is to investigate the effects of TAM (Taraxacum mongolicum) on Th2 cytokine production in MC/9 mast cells. 2. Methods : The effects of TAM was analyzed by ELISA and Real-time PCR in MC/9 mast cells. Levels of IL-5, IL-13 were measured using enzyme-linked immunosorbent assays(ELISA). mRNA levels of IL-4, IL-5, IL-6, IL-13 were analyzed with Real-time PCR. 3. Results : 1) TAM inhibited the IL-4 production significantly in comparison to PI-control group at concentration of $50{\mu}g/ml$, $100{\mu}g/ml$, $200{\mu}g/ml$. 2) TAM inhibited the IL-13 production significantly in comparison to PI-control group at concentration of $50{\mu}g/ml$, $100{\mu}g/ml$, $200{\mu}g/ml$. 3) TAM inhibited the IL-4 mRNA expression significantly in comparison to PI-control group at concentration of $100{\mu}g/ml$. 4) TAM inhibited the IL-5 mRNA expression significantly in comparison to PI-control group at concentration of $50{\mu}g/ml$, $100{\mu}g/ml$. 5) TAM inhibited the IL-6 mRNA expression significantly in comparison to PI-control group at concentration of $100{\mu}g/ml$. 6) TAM inhibited the IL-13 mRNA expression significantly in comparison to PI-control group at concentration of $100{\mu}g/ml$. 4. Conclusions : These results indicate that TAM (Taraxacum mongolicum) has the effect of decreasing the Th2 cytokine production in the MC/9 mast cell.

• IEMEK Journal of Embedded Systems and Applications
• /
• v.11 no.2
• /
• pp.97-105
• /
• 2016

Microcontrollers (MCUs) for endpoint smart sensor devices of internet-of-thing (IoT) are being implemented as system-on-chip (SoC) with on-chip instruction flash memory, in which user firmware is embedded. MCUs directly fetch binary code-based instructions through bit-line sense amplifier (S/A) integrated with on-chip flash memory. The S/A compares bit cell current with reference current to identify which data are programmed. The S/A in reading '0' (erased) cell data consumes a large sink current, which is greater than off-current for '1' (programmed) cell data. The main motivation of our approach is to reduce the number of accesses of erased cells by binary code level transformation. This paper proposes a built-in write/read path architecture using binary code inversion method based on hot-spot region detection of instruction code access to reduce sensing current in S/A. From the profiling result of instruction access patterns, hot-spot region of an original compiled binary code is conditionally inverted with the proposed bit-inversion techniques. The de-inversion hardware only consumes small logic current instead of analog sink current in S/A and it is integrated with the conventional S/A to restore original binary instructions. The proposed techniques are applied to the fully-custom designed MCU with ARM Cortex-M0$^{TM}$ using 0.18um Magnachip Flash-embedded CMOS process and the benefits in terms of power consumption reduction are evaluated for Dhrystone$^{TM}$ benchmark. The profiling environment of instruction code executions is implemented by extending commercial ARM KEIL$^{TM}$ MDK (MCU Development Kit) with our custom-designed access analyzer.

• Asian-Australasian Journal of Animal Sciences
• /
• v.14 no.12
• /
• pp.1775-1780
• /
• 2001

The study was undertaken to find out the normal mean and variations in somatic cell count (SCC) of milk in crossbred and indigenous cows as influenced by stage of lactation, parity and season. On day of milk sampling the udders were tested for mastitis by California Mastitis Test (CMT). Only those cows, which were found negative in the CMT, were taken in the study. Paritywise differences in SCC were not significant between the 1st to 6th lactation and above. Similarly, stage of lactation effect, when tested at 30 day intervals, did not differ significantly. However, the seasons significantly (p<0.05) affected SCC count of milk. The SCC was lower during cold ($1.10{\times}10^5cells/ml$) and hot-dry ($1.11{\times}10^5cells/ml$) season then during hot-humid season ($2.14{\times}10^5cells/ml$). On an average SCC recorded were 1.26, 1.31, 1.54 and $1.61{\times}10^5$ cells per ml respectively in Tharparkar, Sahiwal, Karan Swiss and Karan Fries cows irrespective of stage of lactation, parity and season. Further, crossbred Karan Swiss and Karan Fries cows behave similar to the indigenous Tharparkar and Sahiwal cows but are more vulnerable to hot-humid climate then indigenous ones. Significant correlation between the SCC and milk yield during different stages of lactation (1.38 to $1.74{\times}10^5cells/ml$) and parity (1.47 to $1.63{\times}10^5cells/ml$) suggested that the SCC/ml of milk was higher during the later stages of lactation.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2003.11a
• /
• pp.584-589
• /
• 2003

The hot cell facility which is designed to permit safe handling of source materials with radioactivity levels up to 1,385 TBq, is planned to be built. To meet this goal, the facility is designed to keep gamma and neutron radiation lower than the recommended dose-rate in normally occupied areas. The calculations performed with QAD-CGGP and MCNP-4C are used to evaluate the proposed engineering design concepts that would provide acceptable dose-rates during a normal operation in hot cell facility. The maximum effective gamma dose-rates on the surfaces of the facility at operation area and at service area calculated by QAD-CGGP are estimated to be $2.10{\times}10^{-3}$, $2.97{\times}10^{-2}$ and $1.01{\times}10^{-1}$ mSv/h, respectively. And those calculated by MCNP-4C are $1.60{\times}10^{-3}$, $2.99{\times}10^{-3}$ and $7.88{\times}10^{-2}$ mSv/h, respectively The dose-rates contributed by neutrons are one order of magnitude less than that of gamma sources, and penetration and toboggan will be partly reinforced by lead shield.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2003.11a
• /
• pp.168-171
• /
• 2003

The IMEF(Irradiated Materials Examination Facility), located in KAERI site, is a hot cell facility to test and evaluate the irradiation defects or embrittlement through post-irradiation examination(PIEs) of irradiated nuclear fuels and structural materials which are come from HANARO research reactor and commercial nuclear power plants. Therefore, to carry out its own function, the high level solid radioactive wastes, produced through PIEs, are periodically carried out and managed from hot cell to monolith. So far, approximately 30 drums which contains 50 liters are transported to monolith, and it is shown that the quantity is slowly increasing, In this paper, the procedures and work contents of the high level solid radwaste carrying out and management for IMEF are described in detail.

• Mycobiology
• /
• v.40 no.1
• /
• pp.47-52
• /
• 2012

$Elfvingia$ $applanata$, a medicinal mushroom belonging to Basidiomycota, has been used in the effort to cure cancers of the esophagus and stomach, and is also known to have inhibitory effects on hepatitis B virus infection. The hot water soluble fraction (as Fr. HW) was extracted from fruiting bodies of the mushroom. $In$ $vitro$ cytotoxicity tests showed that hot water extract was not cytotoxic against cancer cell lines such as Sarcoma 180, HT-29, HepG2, and TR at concentrations of 10-2,000 ${\mu}g/mL$. Intraperitoneal injection with Fr. HW resulted in a life prolongation effect of 45.2% in mice previously inoculated with Sarcoma 180. Treatment of Fr. HW resulted in a 2.53-fold increase in the numbers of murine spleen cells at a concentration of 50 ${\mu}g/mL$, compared with control. Incubation of murine spleen cells with Fr. HW at a concentration of 500 ${\mu}g/mL$ resulted in improved immune-potwntiating activity of B lymphocytes through an 8.3-folds increase in alkaline phosphatase activity, compared with control. Fr. HW generated 12.5 ${\mu}M$ of nitric oxide (NO) when cultured with RAW 264.7, a mouse macrophage cell line, at the concentration of 50 ${\mu}g/mL$, while lipopolysaccharide, a positive control, produced 15.2 ${\mu}M$ of NO. Therefore, the results suggested that antitumor activities of Fr. HW from $E.$ $applanata$ might, in part, be due to host mediated immunostimulating activity.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.6
• /
• pp.2765-2769
• /
• 2014

Background: Oesophageal cancer presents high incidence rates in the so-called Brazilian-Uruguayan belt. Materials and Methods: The present study included 1,170 participants (234 cases and 936 controls) which were analyzed by unconditional multiple logistic regression in order to examine risk of oesophageal squamous cell carcinoma (OESCC) associated with several food groups. Results: Boiled red meat (OR 2.59, 95%CI 1.69-3.97), lamb meat (OR 1.64, 95%CI 1.07-2.51), processed meat (OR 1.49, 95%CI 1.01-2.21), whole milk (OR 1.78, 1.19-1.68), fresh vegetables and fruits (OR 0.42, 95%CI 0.27-0.63), mate consumption (OR 2.04, 95%CI 1.32-3.16), and black tea (OR 0.10, 95%CI 0.04-0.28) were significantly associated with risk of OESCC. Conclusions: Hot beverages (mate) and hot foods (boiled meat) appear to be important determinants in the risk of OESCC, allowing the penetration of carcinogens in tobacco and alcohol into the oesophageal mucosa.

• The Korea Journal of Herbology
• /
• v.32 no.6
• /
• pp.41-48
• /
• 2017

Objectives : This study was designed to estimate the antioxidative and neuroprotective effects of Torreyae Semen hot water extracts (TS). Methods : Torreyae Semen was extracted by hot water for 2 hours with a temperature of 105 degrees. Polyphenols and total flavonoid were measured and LC-MS/MS was used to certificate anticipated antioxidative compounds. The antioxidant activities of TS were measured as scavenging effects of 1,1-Diphenyl-2-picrylhydrazyl (DPPH) and Nitrite Oxides (NO). Cell viability and proliferation rate was measured MTT assay. The toxicities to thymocytes and splenocytes were evaluated by the proliferation rate of primary cultured cells of 7 weeks, male Balb/c mice. The antioxidant activities of TS on C6 mouse glioma cells were measured by the analysis of total glutathione contents variation. The neuroprotective effects against oxidative stresses were measured by MTT assay. Results : Polyphenols of TS was $92.00{\pm}1.24{\mu}g/mg$, and total flavonoids was $0.36{\pm}0.14{\mu}g/mg$. TS includes gallocatechin, epigallocatechin, gallocatechin gallate and epigallocatechin gallate. TS included gallocatechin, epigallocatechin, gallocatechin gallate, epigallocatechin gallate. TS showed DPPH and NO scavenging effects as dose-dependent manner at the concentrations of $0-10mg/m{\ell}$. In MTT assay, TS shows no significant toxicity to C6 cells, primary cultured thymocytes and splenocytes of Balb/c mice. TS increased the level of total glutathiones. TS increased cell viabilities of C6 cells against oxidative stresses such as $H_2O_2$, sodium nitroprusside (SNP), Rotenone at the concentrations of $0-0.063mg/m{\ell}$. Conclusions : TS shows the antioxidant and neuroprotecitive effects in these experiments.