• Archives of Pharmacal Research
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• v.21 no.1
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• pp.35-40
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• 1998

Human cytochrome P450 4F2 shows high regioselectivity in hydroxylation of stearic acid and leukotriene $ B_4.$ As a first step of its regulation study, human cytochrome P450 4F2 genomic DNA was isolated from liver of a person who was administered clofibrate for 10 years. From Southern hybridization, restriction enzyme digestion and sequencing experiments, isolated genomic DNA fragment was found to contain around 32 Kb DNA and more than 20 Kb of $5^I$ end regulatory region. Sequences of the structural gene region revealed exon 1 and exon 2. Further regulation studies would elucidate the feedback mechanisms of the oxidative degradation of fatty acids, inflammatory response and the clearance of leukotriene B4 in the liver. Furthermore, regulation study of this gene could explain the species difference in responses to peroxisome proliferator and help in the safety evaluation of peroxisome proliferating chemicals to human being.

• International Journal of Concrete Structures and Materials
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• v.8 no.3
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• pp.185-199
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• 2014

As the national transportation infrastructure ages and deteriorates, many existing bridges require frequent and costly maintenance and repairs. The objective of this work was to synthesize new and existing types of beam end coatings and treatments that have been proven to extend the life of new and existing concrete and steel bridge beams. A comprehensive literature review, along with online surveys and phone interviews of State department of transportations (DOTs) and coating manufacturers was conducted to gather information about existing and recently developed technologies. The study revealed that while many promising coatings and treatments are offered on the market, there is a lack of readily available laboratory results that would enable direct comparison of the available methods. This finding applies in terms of the coatings' durability and the potential for extending the service life of existing bridges. Most of the interviewed State DOTs' personnel assessed the products listed in respective DOT's Qualified Products Lists as performing 'well'. However, there was significant variability between states in the type of the products used. Among the agencies contacted, none was able to suggest the most promising or advanced products, either for concrete or steel bridge beam end treatments. This suggests that comprehensive laboratory evaluation would be necessary for selecting the best available beam end treatments and coatings.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.10B
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• pp.613-620
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• 2007

Recently, due to the developing of broadband convergence networks, the high quality multimedia services which are converged with communication and broadcasting can be provided. These high quality communication and broadcasting convergence service needs reliable multicasting mechanism in IP networks. However, multicasting mechanism recently deployed is difficult to guarantee the end-to-end QoS. For the reliable high quality If multimedia IPTV service, the QoS guaranteed multicasting mechanism should be provided. Therefore, we proposed a probing packet based multicasting admission control mechanism using centralized multicasting control management block in this paper. And for the performance evaluation of the proposed mechanism, we used ns-2 simulator.

• The Journal of the Korea institute of electronic communication sciences
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• v.15 no.6
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• pp.1011-1016
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• 2020

Rapid change in network topology in high-speed VANET(: Vehicular Ad Hoc Network) is an important task for routing protocol design. Selecting the next hop relay node that affects the performance of the routing protocol is a difficult process. The disadvantages of AODV(: Ad Hoc On-Demand Distance Vector) related to VANET are end-to-end delay and packet loss. This paper proposes the AAODV (Advanced AODV) technique to reduce the number of RREQ (: Route Request) and RREP (: Route Reply) messages by modifying the AODV routing protocol and adding direction parameters and 2-step filtering. It can be seen that the proposed AAODV reduces packet loss and minimizes the effect of direction parameters, thereby increasing packet delivery rate and reducing end-to-end delay.

• Journal of Korean Society of Steel Construction
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• v.22 no.2
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• pp.121-128
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• 2010

The current trends in steel construction involve the use of tapered sections to minimize the use of excess materials to the extent possible, by choosing cross-sections that are as economical as possible abandoning the classical approach of using prismatic members. In addition, snug-tightened connections, especially the end-plate type, have the advantage of fetching less construction costs and shorter assembly times as opposed to fully tightened joints. Although they have many merits, however, snug-tightened bolted end plates are extremely complex in their structural behavior. In this study, an experimental investigation of the snug-tightened flush end-plate connections of tapered beams were conducted. The primary test parameters were the torque for the clamping bolt, the loading pattern, the bolt type and the connection failure type. Using initial stiffness and load-carrying capacity as proposed by Silva et al. and AISC (2003), the moment-rotation curve of a linearly tapered member with a snug-tightened flush end-plate connection was predicted. Moreover, numerical and experimental data for moment-rotation curves were compared.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.17 no.4
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• pp.104-111
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• 2008

The objective of this study is to evaluate micro end-milling characteristics and tool wear behavior of AlN-hBN composites. First, AlN based composites with hBN contents in the range of 10 to 20vol% were prepared by hot-pressing. Vickers hardness and flexural strength of the prepared composite specimens were measured and compared according to the vol% of hBN variations. Then, cutting force variations were measured and analyzed using a tool dynamometer during the micro end-milling experiments; and machined surface shapes and roughness were investigated using a 3D non-contact type surface profiler. After micro end-milling, worn tools were investigated using a tool microscope and SEM images. From the experimental results, it can be observed that the cutting forces decreased, and surface qualities were improved with increasing hBN contents. At low content of hBN, tool chipping was observed; and tool wear rate decreased with increasing hBN contents. The results of this study insist that proper machining conditions, including tool wear behavior investigation, should be determined for the micro end-milling of AlN-hBN composites for its further application.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.4
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• pp.9-17
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• 2010

The mobility of nodes are different in wireless ad hoc networks. Routes have to be refreshed frequently due to the mobility of the nodes acting as routers. Path consists of a few highly mobile nodes should be avoided to forward packets, because even only one highly mobile node may result in the break of path. We develop a mobility aware method to evaluate path stability for multipath routing in wireless Ad Hoc networks. Specifically, we extend it to a well-studied multipath routing protocol known as ad hoc on-demand multipath distance vector (AOMDV). The resulting protocol is referred to as path stability evaluation (PSE). Performance comparison of AOMDV with PSE are studied through ns-2. Simulation shows that PSE has optimistic results in performance metrics such as packet delivery, end-to-end delay, routing overhead and throughput.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.10 no.5
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• pp.201-208
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• 2010

Mobile Ad Hoc Network(MANET) has highly dynamic topology, hence presents a great challenge on the network performance evaluation and network protocol design. We proposed total path break up time, $\sum_{i}T_i$, as a metric to measure the performance of the total system as well as an individual connection. In this paper, we evaluate and analyze the performance of three mobility models(Random Waypoint, Manhattan, Blocked Manhattan) by applying the total path break up metric, investigate why network parameters such as packet delivery ratio, end-to-end delay, etc. vary by mobility models. We also present analysis result how much AODV Buffer improve packet delivery ratio and increase the end-to-end delay in spite of the path break up.

• Journal of Korean Academy of Nursing
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• v.42 no.4
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• pp.453-465
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• 2012

Purpose: The study was done to develop a shared decision-making scale for end-of-life patients in Korea. Methods: The process included construction of a conceptual framework, generation of initial items, verification of content validity, selection of secondary items, preliminary study, and extraction of final items. The participants were 388 adults who lived in one of 3 Korean metropolitan cities: Seoul, Daegu, or Busan. Item analysis, factor analysis, criterion related validity, and internal consistency were used to analyze the data. Data collection was done from July to October 2011. Results: Thirty-four items were selected for the final scale, and categorized into 7 factors explaining 61.9% of the total variance. The factors were labeled as sharing information (9 items), constructing system (7 items), explanation as a duty (5 items), autonomy (4 items), capturing time (3 items), participation of family (3 items), and human respect (3 items). The scores for the scale were significantly correlated among shared decision-making scale, terminating life support scale, and dignified dying scale. Cronbach's alpha coefficient for the 34 items was .94. Conclusion: The above findings indicate that the shared decision-making scale has a good validity and reliability when used for end-of-life patients in Korea.

• Journal of the Korea Concrete Institute
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• v.11 no.4
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• pp.43-54
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• 1999

Shear tests are performed on four full-scale 12.5 m proto-type models, "least depth double tee," which are resulted from the optimization process. Domestic superimposed live load regulation, domestic material properties which is available to product. Korean building code requirements, construction environments and economy are considered as the main factors to establish the process. All of the specimens tested fully comply with the shear strength requirements as specified by ACI 318-95. The research has shown following results. 1) The development length requirement of ACI 318-95 does not seem a good predictor for the estimation of bond failure in a beam with the strands below the supports. 2) The load required for the first initial coner cracking in the dap end and first web shear cracking does not seem to have any relation with the dimension and shear strength of the section in the test beams. 3) The strand slip has a direct relationship with the web shear cracking. However, the coner cracking in the dap end does not give any help for the slip in anchorage. 4) Use of whole area for bearing steel at the bottom of dap end is desired for safe bearing pressure design in the precast prestressed double tee beams. 5) The deflection of beam influences directly on the amount of strand slip at the anchorage after initiation of it, and relationship between them are very linear.