• Journal of Agricultural Extension & Community Development
• /
• v.11 no.1
• /
• pp.83-93
• /
• 2004

This paper investigated the characteristics of population structure and the determinants of population movement in the south west area of Kyonggi-do by grouping 9 cities in 3 categories and using Panel data of $1995{\sim}2001$. The major findings of this paper were identified as follows : 1) The population structure of regions was different to the stages of urbanization. The ratio of child and elder dependency was high in the rural regions and low in the urbanized regions. It was due to the movement of economically active population of $20{\sim}40$ aged groups, from rural regions to urban regions. This means that more productive segments of the rural population leave the country to the city. In addition. The ratio of male to female was higher in $20{\sim}40$ aged groups for rural regions. This suggested that young females moved from rural regions to urban regions more than young males in the process of industrialization. 2) Based in pooling regression, income was the most significant determinant that could explain the inter-regional and intra-regional movement of population for south west area studied, The next one was educational opportunity variable. The coefficients of income and education were 0.5, 0,7 for intra-regional migration and 0.01, 0.02 for interregional migration indicating that Todaro's hypothesis could be tested well rather than Tiebout' model for this area.

• Ocean and Polar Research
• /
• v.24 no.3
• /
• pp.189-196
• /
• 2002

A multichannel seismic survey was conducted in the southern Ayu Trough which is the only spreading boundary between the Philippine Sea and Caroline plates. The seismic system used in this study comprises of 2.46-l sleeve gun and a 12-channel streamer with a group interval of 6.25m. Migration technique was used to analyze seismic velocity, and poststack depth migration was applied to the stacked data. The sediment thickness obtained from the depth section tends to increase with distance from the spreading axis. Sedimentation rates are poorly constrainted in the study area. The apparent half-spreading rates estimated from the sediment thickness and sedimentation rate from DSDP hole on the caroline plate are 4.7mm/yr and 7.9mm/yr at $1^{\circ}24'N\;and\;0^{\circ}42'N$, respectively, which are fester than Previously suggested. On the basis of new oblique spreading geometry, the recalculated spreading rates are 5.4mm/yr and 9.1mm/yr at $1^{\circ}24'N\;and\;0^{\circ}42'N$, respectively. Seismic sections show that the topography is asymmetric across the Ayu Trough and the acoustic basement is rough. These features are consistent with the earlier suggestion that the Ayu Trough is a slow-spreading divergent boundary. A detailed examination of seismic profiles away from the axis shows that sediments can be divided into two layers which implies a possible change in the spreading rate anuor sedimentation condition during the formation of the trough.

• Biomolecules & Therapeutics
• /
• v.20 no.6
• /
• pp.556-561
• /
• 2012

Steroid sulfatase (STS) is responsible for the conversion of estrone sulfate to estrone that can stimulate growth in endocrine-dependent tumors such as prostate cancer. Although STS is considered as a therapeutic target for the estrogen-dependent diseases, cellular function of STS are still not clear. Previously, we found that tumor necrosis factor (TNF)-${\alpha}$ significantly enhances steroid sulfatase expression in PC-3 human prostate cancer cells through PI3K/Akt-dependent pathways. Here, we studied whether bacterial lipopolysaccharides (LPS) which are known to induce TNF-${\alpha}$ may increase STS expression. Treatment with LPS in PC-3 cells induced STS mRNA and protein in concentration- and time-dependent manners. Using luciferase reporter assay, we found that LPS enhanced STS promoter activity. Moreover, STS expression induced by LPS increased PC-3 tumor cell migration determined by wound healing assay. We investigated that LPS induced IL-6 expression and IL-6 increased STS expression. Taken together, these data strongly suggest that LPS induces STS expression through IL-6 pathway in human prostate cancer cells.

• The Journal of the Korean dental association
• /
• v.21 no.10 s.173
• /
• pp.805-812
• /
• 1983

For the assessment of peripheral blood leukocyte chemotaxis dysfunction in rapidly progressive periodontitis, peripheral blood leukocyte of 13 patients were isolated, and tested by the method of blind well chamber technique which was recently developed by Park. Data analysis was performed from the speed of cell migration from the bottom of filter paper to the top for 18 minutes at the condition of chemo-attractant(Zymosan-activated serum). Eight of the 13 patients (62%) exhibited statistically significant inhibition of leukocyte chemotaxis, 4 patients revealed normal function and the other one patients showed elevated leukocyte chemotaxis. Four of the 8 patients in chemotaxis dysfunction showed significant inhibition of random migration and chemotaxis dysfunction both. Two of these 4 patients exhibited random migration impairment, elevation of C.D.I. and chemotaxis dysfunction. The results indicated that the progression of rapidly progressive periodontitis was influenced by the leukocyte chemotaxis dysfunction, and half of these dysfunction was associated with cell-defect of leukocyte.

• Korea journal of population studies
• /
• v.14 no.1
• /
• pp.1-25
• /
• 1991

The Purpose of this study is to analyze the contribution of the total human capital formation to economic growth in Korea. In order to assess the contribution of the total human capital formation to economic growth, aggregate production functions are estimated using two ways of ordinary least squares and polynomial distributed lags based on 1955 - 1988 time series data in Korea. The total amount of investment in human capital is calculated by adding each amount of investment in formal education, vocational training, inter-provincial migration, and health in pecuniary terms. The findings of this study could be summarized as follows ; (1) If we enumerate the variables in good order according to the importance, we get the following ; namely, total number of labor force, inter-provincial migration, vocational training, health, physical capital, and formal education. (2) The contribution of the human capital to economic growth is much more larger than that of physical capital. In particular, it appears that inter-provincial migration and vocational training make a great contribution to economic growth. (3) It appears that investment in formal education has a continuous effect for fifteen years and maximum effect is observed approximately eight years later. In the case of vocational training, the effect of investment lasts for about 12-14 years and its effect on economic growth reaches maximum with the passage of seven to eight years after initial investment. (4) Investment in vocational training contributes more in the long run compared with investment in formal education. The effect of investment in formal education lasts longer than that of vocational training, while the effect of investment in vocational training is considerably larger in the short run compared with the investment in formal education.

• Journal of Ecology and Environment
• /
• v.29 no.1
• /
• pp.1-16
• /
• 2006

Environmental variables, fishing and biological data of the common squid, Todarodes pacificus were used to describe changes in structure, migration and abundance of the squid population in relation to ocean climate shifts. It was possible to consider the main groups of the squid (autumn and winter-spawned groups) as a single population to aid conservation in the waters around Korea and Japan (TWC and KOC regions). The patterns of yearly fluctuations in abundance of the squid population in the two regions were the same during 52 years of $1952{\sim}2003$. The abundance of the squid began to decrease in both regions in the early 1970s, remained low in the 1980s and the main squid groups synchronously increased in the 1990s coincident with favorable changes of thermal conditions and plankton production in those ecosystems. The mechanisms of changes in the structure, distribution and abundance of common squid population in relation to current-mediated migration circuits are explained on the basis of phenological variables responding to climate shifts.

• Biomedical Science Letters
• /
• v.25 no.2
• /
• pp.149-158
• /
• 2019

The objective of this study was to evaluate the effects of thoracic mobilization (TM) on the angle of thoracic kyphosis, and static and dynamic balances by application period. The subjects of this study were 18 adult males and females (${\geq}20years\; old$) who had the angle of thoracic kyphosis equal to or higher than $40^{\circ}$. A pre-test was conducted for all subjects and TM was carried out. Data were collected before the intervention, 3 weeks after the intervention, and 6 weeks after the intervention. It was measured three times per measurement and mean values were used for the analysis. The results of this study showed that the angle of thoracic kyphosis significantly (P<.05) decreased after applying TM. However, the migration area ($mm^2$) of the center of pressure (COP) in the static balance did not vary significantly. In the case of the dynamic balance, when eyes were open, the migration area ($mm^2$) of the COP significantly (P<.05) decreased after 3 weeks. When eyes were open, the migration area ($mm^2$) of the COP significantly (P<.05) decreased after 3 weeks and 6 weeks. Therefore, an intervention for improving the human body alignment and balance should be applied for a long-term, rather than a short-term, in order to be effective.

• Molecules and Cells
• /
• v.42 no.8
• /
• pp.589-596
• /
• 2019

${\beta}Pix$ is a guanine nucleotide exchange factor for the Rho family small GTPases, Rac1 and Cdc42. It is known to regulate focal adhesion dynamics and cell migration. However, the in vivo role of ${\beta}Pix$ is currently not well understood. Here, we report the production and characterization of ${\beta}Pix$-KO mice. Loss of ${\beta}Pix$ results in embryonic lethality accompanied by abnormal developmental features, such as incomplete neural tube closure, impaired axial rotation, and failure of allantois-chorion fusion. We also generated ${\beta}Pix$-KO mouse embryonic fibroblasts (MEFs) to examine ${\beta}Pix$ function in mouse fibroblasts. ${\beta}Pix$-KO MEFs exhibit decreased Rac1 activity, and defects in cell spreading and platelet-derived growth factor (PDGF)-induced ruffle formation and chemotaxis. The average size of focal adhesions is increased in ${\beta}Pix$-KO MEFs. Interestingly, ${\beta}Pix$-KO MEFs showed increased motility in random migration and rapid wound healing with elevated levels of MLC2 phosphorylation. Taken together, our data demonstrate that ${\beta}Pix$ plays essential roles in early embryonic development, cell spreading, and cell migration in fibroblasts.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.10 no.9
• /
• pp.4207-4222
• /
• 2016

In a P2P (Peer-to-Peer) VoD (video-on-Demand) streaming system, the nodes' load is an important factor which affects the system performance. In the system, some nodes may receive too many requests, which leads to overload. On the other hand, some other nodes may receive too few requests, which leads to low utilization. Therefore, designing a reasonable load balancing strategy is important. However, existing related studies cannot handle this problem effectively, because they don't have an efficient dynamic load information management mechanism, and they don't distinguish the difference of requests when transfer the nodes' load. In this paper, to manage the dynamic load information efficiently, we design a load management table for each node. Based on the load information, we propose a load balancing strategy which uses a request migration algorithm (LBRM). Through simulations, our scheme can handle the load imbalance problem effectively and improve the users' playback fluency.

• Korean Journal of Applied Biomechanics
• /
• v.25 no.4
• /
• pp.475-482
• /
• 2015

Objective : The purpose of this study was to investigate mean plantar foot pressure, maximum plantar pressure and ground reaction force, and center migration path of pressure according to the type of trekking shoes for the development of shoes. Method : Subjects of the study averaged $22.10{\pm}2.05years$ of age. Their average height was $169.27{\pm}7.62cm$ and their average weight was $64.34{\pm}10.22kg$. The method of this study was administered measuring 50 steps, at once, 3 times at a speed of 4 km/h and using the data of 30 steps. Pedar-X system measured the mean foot pressure, maximum foot pressure, mean maximum force, and center migration path of pressure by subjects' position while walking. Statistical analysis was performed by SPSS 23.0 using a paired t-test. Results : Results of the study showed Nestfit trekking shoes lower foot pressure of both feet in mean foot pressure and maximum foot pressure. Nestfit trekking shoes showed high ground reaction force (p<.001) in the midfoot, and low mean ground reaction force in the rearfoot. The center migration path of pressure showed the Nestfit trekking shoes were more stable than flat insole trekking shoes. Conclusion : It can be concluded that wearing Nestfit trekking shoes spreads pressure efficiently and induces walking stability because Nestfit trekking shoes spread the pressure of the forefoot and rearfoot to the midfoot and the center migration path of pressure shows regularly.