• Title/Summary/Keyword: Cell permeability

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Analysis of Shielding Effectiveness and Estimation of Shielding Factor in Conductive and Magnetic Shields (도전성 및 자성 차폐체의 차폐효과 해석과 차폐인수 산정)

  • Kang, Dae-Ha
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.27 no.10
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    • pp.30-40
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    • 2013
  • In this study the method based on flux linkage in cell was introduced in calculation of eddy currents by cell method. According to this method eddy current distribution and the loss can be evaluated and since the shielding effectiveness by flux cancelation of eddy current can be analyzed, this method is applicable to design of conductive shield. And also the formula of shielding factor were so deduced as to be applicable to finite-width infinite-length shielding sheets and infinite-length underground cable shield. These formula are adaptable to magnetic materials as well as conductive materials. As the results of calculation in model shields are follows. In case of finite-width infinite-length shielding sheet, shielding effectiveness increases with increasing of conductivity. In case of infinite-length underground cable shield, the effectiveness become higher with increasing of permeability. Especially the effectiveness is very high in materials with both high conductivity and permeability in underground cable shield.

Effect of Saururus chinensis (Lour.) Baill. Aquacupuncture on Anaphlylaxis in Mice (삼백초약침액(三白草藥鍼液)이 아나필락시스에 미치는 영향)

  • Choi, Kyu-Jung;Lee, So-Young;Kang, Kyung-Hwa;Lee, Yong-Tae;Song, Choon-Ho
    • Korean Journal of Acupuncture
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    • v.21 no.3
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    • pp.97-104
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    • 2004
  • Objective We investigated the effect of Saururus chinensis (Lour.) Baill. aquacupuncture (SCB) on anaphylaxis in mice. Methods : We conformed compound 48/80-induced mesenteric mast cell degranulation, active systemic anaphylatic shock and histamine release. Also observed acetic acid-induced vascular permeability and anti-dinitrophenyl (DNP) IgE-mediated passive cutaneous anaphylaxis. Results : SCB inhibited mesenteric mast cell degranulation and active systemic anaphylatic shock induced by compound 48/80 dose-dependently. When SCB was pretreated by intra-peritoneal injection, the serum histamine levels were reduced. SCB also significantly inhibited acetic acid-induced vascular permeability. In addition, SCB showed a significant inhibitory effect on anti-dinitrophenyl (DNP) IgE-mediated passive cutaneous anaphylaxis. Conclusion : These results indicated that SCB inhibits anaphylatic reaction.

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A Detailed Examination of Various Porous Media Flow Models for Collection Efficiency and Pressure Drop of Diesel Particulate Filter (DPF의 PM 포집효율 예측을 위한 다양한 다공성 매질 유동장 모델 해석)

  • Jung, Seung-Chai;Yoon, Woong-Sup
    • Transactions of the Korean Society of Automotive Engineers
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    • v.15 no.1
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    • pp.78-88
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    • 2007
  • In the present study a detailed examination of various porous media models for predicting filtration efficiency and pressure drop of diesel particulate filter (DPF), such as sphere-in-cell and constricted tube models, are attempted. In order for demonstrating their validities of correct estimation on permeability, geometry of property configurations common in commercial cordierite DPFs are correlated to the porous media flow models, and validations of predicted filtration efficiencies due to the use of different unit collectors are made with experiments. The result shows that the porosity, pore size and permeability of cordierite DPF can be successfully correlated by Kuwabara flow field with correction factor of 0.6. The unit collector efficiency predicted by sphere-in-cell model agrees very well with measurements in accumulation mode, whereas that by constricted tube model with significant prediction error.

Studies on the Methanol Permeability through PVA/SSA Ion Exchange Membranes Substituted with Various Metal Cations (금속이온으로 치환된 PVA/SSA 이온교환막의 메탄올 투과특성 연구)

  • 이충섭;정선영;전지현;신현수;임지원
    • Membrane Journal
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    • v.12 no.1
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    • pp.51-53
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    • 2002
  • The hydrogen ions in poly (vinyl alcohol) (PVA)/sulfosuccinic acid (SSA) membranes substiuted with $Li^+, Na^+, and K^+/ $of monvoalent metal ions, $Mg^{2+}, Ca^{2+} and Ba^{2+}$ of divalent metal ions, and $Al^{3+}$ of trivalent metal ion. In addition, $Li^+ ions were exchanged with varing reaction time. The effects of metal ions exchanged were investigated in terms of methanol permeability -uling diffusion cell. The methanol permeabilies decreased in the sequence of $Na^+, Li^+ and K^+$ and this might be due to the 'Salting-out' effect while the methanol permeabilities for divalent and trivalent ion-substituted membranes were affected by the combined effects of salting-out, eletrostatic crosslinking and extent of metal ion substiution. As for $Li^+$ ions, methanol permeabilities of PVA/SSA membranes decreased in proportion to the degrees of subsituted $Li^+$ ions.

Anti-aging potential of fish collagen hydrolysates subjected to simulated gastrointestinal digestion and Caco-2 cell permeation

  • Je, Hyun Jeong;Han, Yoo Kyung;Lee, Hyeon Gyu;Bae, In Young
    • Journal of Applied Biological Chemistry
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    • v.62 no.1
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    • pp.101-107
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    • 2019
  • The objectives of this study were to evaluate the anti-aging effects and investigate the effect of simulated gastrointestinal (GI) digestion on the anti-aging properties and intestinal permeation of the potential fish collagen hydrolysates (FCH). Therefore, procollagen synthesis, matrix metalloproteinase-1 (MMP-1) production, and Caco-2 cell permeability were analyzed before and after in vitro digestion for FCHs, low-molecular weight fractions (<1 kDa), and high molecular weight fractions (>1 kDa). After being subjected to GI digestion, the level of MMP-1 inhibition was maintained, although the procollagen production was significantly (>20%) lower with all samples. Also, the digested FCHs and their <1 kDa fraction yielded 9.1 and 13.8% increased peptide transport, respectively, compared to undigested samples. Based on the effective intestinal permeation and high digestive enzyme stability, the <1 kDa fraction of FCHs is a potential bioactive material suitable for anti-aging applications in the food and cosmetics industries.

Fabrication of Electrolyte for Direct Carbon Fuel Cell and Evaluation of Properties of Direct Carbon Fuel Cell (직접탄소 연료전지용 전해질 제조 및 직접탄소 연료전지 특성 평가)

  • Pi, Seuk-Hoon;Cho, Min-Je;Lee, Jong-Won;Lee, Seung-Bok;Lim, Tak-Hyoung;Park, Seok-Joo;Song, Rak-Hyun;Shin, Dong-Ryul
    • Korean Chemical Engineering Research
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    • v.49 no.6
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    • pp.786-789
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    • 2011
  • In order to estimate the possibility of applying electrolytes generally used in solid oxide fuel cells(SOFCs) to direct carbon fuel cells(DCFCs), properties of YSZ(yttria stabilized zirconia) electrolyte were evaluated. In this study, vacuum slurry coating method was adapted to coat thin layer on anode support substrate. After sintering the electrolyte at $1400^{\circ}C$ for 5hrs, microstructure was analyzed by using SEM image. Also, gas permeability and ionic conductivity were measured to find out the potential possibility of electrolyte for DCFCs. The YSZ electrolyte represented dense coating layer and low gas permeability value. The ionic conductivity of YSZ electrolyte was high over $800^{\circ}C$. After measurement of the electrolyte properties, direct carbon fuel cell was fabricated and its performance was measured at $800^{\circ}C$.

Effect of the Pore Structure on the Anodic Property of SOFC (SOFC 음극의 기공구조가 음극특성에 미치는 영향)

  • 허장원;이동석;이종호;김재동;김주선;이해원;문주호
    • Journal of the Korean Ceramic Society
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    • v.39 no.1
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    • pp.86-91
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    • 2002
  • Solid Oxide Fuel Cells (SOFC) are of great interest of next generation energy conversion system due to their high energy efficiency and environmental friendliness. The basic SOFC unit consists of anode, cathode and solid electrolyte. Among these components, anode plays the most important role for the oxidation of fuel to generate electricity and also behaves as a substrate of the whole cell. It is normally requested that the anode materials should have the high electrical conductivity and gas permeability to reduce the polarization loss of the cell. In this study, the effect of pore former on the microstructure of anode substrate was investigated and thus on the electrical conductivity and the gas permeability. According to the results, microstructure and electrical conductivity of anode substrate were greatly influenced by the shape of pore former and especially by the anisotrpy of the pore former. The use of anisotropic pore former is supposed to deteriorate the cell performance by which the electrical conduction path is disconnected but also the effective gas diffusion path for the fuel is reduced.

Higher Expression of TRPM7 Channels in Murine Mature B Lymphocytes than Immature Cells

  • Kim, Jin-Kyoung;Ko, Jae-Hong;Nam, Joo-Hyun;Woo, Ji-Eun;Min, Kyeong-Min;Earm, Yung-E;Kim, Sung-Joon
    • The Korean Journal of Physiology and Pharmacology
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    • v.9 no.2
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    • pp.69-75
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    • 2005
  • TRPM7, a cation channel protein permeable to various metal ions such as $Mg^{2+}$, is ubiquitously expressed in variety of cells including lymphocytes. The activity of TRPM7 is tightly regulated by intracellular $Mg^{2+}$, thus named $Mg^{2+}$-inhibited cation (MIC) current, and its expression is known to be critical for the viability and proliferation of B lymphocytes. In this study, the level of MIC current was compared between immature (WEHI-231) and mature (Bal-17) B lymphocytes. In both cell types, an intracellular dialysis with $Mg^{2+}$-free solution (140 mM CsCl) induced an outwardly-rectifying MIC current. The peak amplitude of MIC current and the permeability to divalent cation ($Mn^{2+}$) were several fold higher in Bal-17 than WEHI-231. Also, the level of mRNAs for TRPM7, a molecular correspondence of the MIC channel, was significantly higher in Bal-17 cells. The amplitude of MIC was further increased, and the relation between current and voltage became linear under divalent cation-free conditions, demonstrating typical properties of the TRPM7. The stimulation of B cell receptors (BCR) by ligation with antibodies did not change the amplitude of MIC current. Also, increase of extracellular $[Mg^{2+}]_c$ to enhance the $Mg^{2+}$ influx did not affect the BCR ligation-induced death of WEHI-231 cells. Although the level of TRPM7 was not directly related with the cell death of immature B cells, the remarkable difference of TRPM7 might indicate a fundamental change in the permeability to divalent cations during the development of B cells.

Characterization of SPAES Composite Membrane Containing Variously Funtionallized MMT for Direct Methanol Fuel Cell Application (다양한 관능기를 포함한 MMT/SPAES 복합막의 직접 메탄올 연료전지용 적용을 위한 특성평가)

  • Kim, Deuk-Ju;Hwang, Hae-Young;Kim, Se-Jong;Hong, Young-Taik;Kim, Hyoung-Juhn;Leem, Tae-Hoon;Nam, Sang-Yong
    • Journal of Hydrogen and New Energy
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    • v.22 no.1
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    • pp.42-50
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    • 2011
  • The Montmorillonite (MMT) in the polymer matrix is expected to reduce methanol permeability due to the tortous path formed by dispersed silicate layers. However, the polymer composite membranes containing non-proton conducting inorganic particle tend to show low proton conductivity. To solve this problem, we used an ion exchange method to prepare functionalized MMT with various silane coupling agents. The modified MMT was randomly dispersed in sulfonated poly (arylene ether sulfone) (SPAES) matrix to prepare SPAES/modified MMT composite membranes. The performances of hybrid membranes for DMFCs application were investigated. The SPAES/modified composite membrane showed increased proton conductivity compared with the non-modified MMT composite membrane. However, the methanol permeability of the SPAES/modified membrane was higher than that of the non-modified MMT.

Studies on Skin Permeation with Polymer Micelles and the Cell Penetrating Peptide of Pyrus Serotina Var Stem Extracts

  • An, Gyu Min;Park, Su In;Kim, Min Gi;Heo, Soo Hyeon;Shin, Moon Sam
    • Korean Chemical Engineering Research
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    • v.58 no.1
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    • pp.21-28
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    • 2020
  • The stem extract from Pyrus serotina var has natural antioxidant ability, but the extraction method does not result in a soluble compound in cosmetic formulations. This study investigated the cosmetic efficacy of the Pyrus serotina var stem extract and its epidermis permeation ability when combined with polymer micelles and a cell penetrating peptide. The total concentration of polyphenol compounds was determined to be 103.1644 ± 1.38 mg/g in the ethanol extract and 78.97 ± 1.45 mg/g in the hydrothermal extract. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging effects were 55.94 ± 0.22% in the ethanol extract at 1,000 mg/L. Superoxide dismutase (SOD) activity rates were 104.05 ± 3.28% in the ethanol extract at 62.5 mg/L. The elastase inhibition rate was 67.21 ± 2.72% in the ethanol extract at 1,000 mg/L. An antimicrobial effect was observed in the Propionibacterium acnes strain. In the epidermal permeability experiment, it was confirmed that formulation of the polymer micelle containing the Pyrus serotina var stem extract and cell penetrating peptide (R6, hexa-D-arginine) showed small particle size and much better skin permeability. The cumulative amount of total Pyrus serotina var stem extract that penetrated to the skin over time increased over 24 hours in three formulations. The three formulations showed 51.61 ㎍/㎠ (Formulation 0), 75.97 ㎍/㎠ (Formulation 1) and 95.23 ㎍/㎠ (Formulation 2) skin penetration, respectively. Therefore, it was confirmed that the ethanol extracts of Pyrus serotina var stem showed good cosmetic efficacy and excellent epidermis permeation ability when combined with a polymer micelle and cell penetrating peptide. Thus, this extract has the potential to be used as a safe and natural cosmetic material in the future.