Korean Journal of Acupuncture
- Volume 21 Issue 3
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- Pages.97-104
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- 2004
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- 2287-3368(pISSN)
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- 2287-3376(eISSN)
Effect of Saururus chinensis (Lour.) Baill. Aquacupuncture on Anaphlylaxis in Mice
삼백초약침액(三白草藥鍼液)이 아나필락시스에 미치는 영향
- Choi, Kyu-Jung (Dept. of Meridian & Acupoint.Research Institute, College of Oriental Medicine, Dongeui University) ;
- Lee, So-Young (Dept. of Physiology.Biomedical Research Center, College of Oriental Medicine, Dongeui University) ;
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Kang, Kyung-Hwa
(Dept. of Physiology.Biomedical Research Center, College of Oriental Medicine, Dongeui University) ;
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Lee, Yong-Tae
(Dept. of Physiology.Biomedical Research Center, College of Oriental Medicine, Dongeui University) ;
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Song, Choon-Ho
(Dept. of Meridian & Acupoint.Research Institute, College of Oriental Medicine, Dongeui University)
- 최규정 (동의대학교 한의과대학 경혈학교실.한의학연구소) ;
- 이소영 (동의대학교 한의과대학 생리학교실.한방바이오연구센터) ;
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강경화
(동의대학교 한의과대학 생리학교실.한방바이오연구센터) ;
-
이용태
(동의대학교 한의과대학 생리학교실.한방바이오연구센터) ;
-
송춘호
(동의대학교 한의과대학 경혈학교실.한의학연구소)
- Published : 2004.09.27
Abstract
Objective We investigated the effect of Saururus chinensis (Lour.) Baill. aquacupuncture (SCB) on anaphylaxis in mice. Methods : We conformed compound 48/80-induced mesenteric mast cell degranulation, active systemic anaphylatic shock and histamine release. Also observed acetic acid-induced vascular permeability and anti-dinitrophenyl (DNP) IgE-mediated passive cutaneous anaphylaxis. Results : SCB inhibited mesenteric mast cell degranulation and active systemic anaphylatic shock induced by compound 48/80 dose-dependently. When SCB was pretreated by intra-peritoneal injection, the serum histamine levels were reduced. SCB also significantly inhibited acetic acid-induced vascular permeability. In addition, SCB showed a significant inhibitory effect on anti-dinitrophenyl (DNP) IgE-mediated passive cutaneous anaphylaxis. Conclusion : These results indicated that SCB inhibits anaphylatic reaction.
Keywords
- Saururus chinensis (Lour.) Baill. aquacupuncture;
- Anaphylaxis;
- Active systemic anaphylatic shock;
- Passive cutaneous anaphylaxis