• The Korea Journal of Herbology
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• v.37 no.1
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• pp.41-50
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• 2022

Objectives : The aim of this study was to investigate the effect of water extract of Agastache rugosa (AR) on productions of inflammatory mediators in lipopolysaccharide (LPS)-stimulated RAW 264.7 mouse macrophages. Methods : Cell viabilities were measured with MTT assay. The production of nitric oxide (NO) from RAW 264.7 cells was measured with Griess reagent assay. The production of cytokines in RAW 264.7 cells was measured with multiplex cytokine assay. Results : AR showed no cytotoxicity on RAW 264.7 cells. AR at concentrations of 25, 50, 100, and 200 ㎍/mL significantly inhibited NO production in LPS-stimulated RAW 264.7 cells. AR at concentrations of 50, 100, and 200 ㎍/mL significantly inhibited productions of TNF-α and IL-1β in LPS-stimulated RAW 264.7 cells; AR at concentrations of 50 and 200 ㎍/mL significantly inhibited productions of RANTES (CCL5) in LPS-stimulated RAW 264.7 cells; AR at concentrations of 100 ㎍/mL significantly inhibited productions of macrophage inflammatory protein-1β in LPS-stimulated RAW 264.7 cells; AR at concentrations of 50, 100, and 200 ㎍/mL significantly increased productions of IP-10 (CXCL10) in LPS-stimulated RAW 264.7 cells; AR at concentrations of 100 and 200 ㎍/mL significantly increased MCP-1 (CCL-2) in LPS-stimulated RAW 264.7 cells; AR at concentrations of 50 and 100 ㎍/mL significantly increased productions of IL-10 in LPS-stimulated RAW 264.7 cells. Conclusions : AR might have immunomodulatory effects on productions of NO, cytokines, and chemokines in LPS-stimulated RAW 264.7 mouse macrophages.

• Journal of Electrochemical Science and Technology
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• v.13 no.4
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• pp.453-461
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• 2022

A chemically sintered and binder-free paste of TiO₂ nanoparticles (NPs) was prepared using a binary-liquid mixture of 1-octanol and CCl₄. The 1:1 (v/v) complex of CCl₄ and 1-octanol easily interacted chemically with the TiO₂ NPs and induced the formation of a highly viscous paste. The as-prepared binary-liquid paste (P_BL)-based TiO₂ film exhibited the complete removal of the binary-liquid and residuals with the subsequent low-temperature sintering (~150℃) and UV-O₃ treatment. This facilitated the fabrication of TiO₂ photoanodes for flexible dye-sensitized solar cells (f-DSSCs). For comparison purposes, pure 1-octanol-based TiO₂ paste (P_O) with moderate viscosity was prepared. The P_BL-based TiO₂ film exhibited strong adhesion and high mechanical stability with the conducting oxide coated glass and plastic substrates compared to the P_O-based film. The corresponding low-temperature sintered P_BL-based f-DSSC showed a power conversion efficiency (PCE) of 3.5%, while it was 2.0% for P_O-based f-DSSC. The P_BL-based low- and high-temperature (500℃) sintered glass-based rigid DSSCs exhibited the PCE of 6.0 and 6.3%, respectively, while this value was 7.1% for a 500℃ sintered rigid DSSC based on a commercial (or conventional) paste.

• Proceedings of the Korean Institute of Resources Recycling Conference
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• 2005.10a
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• pp.266-270
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• 2005

본 연구는 Ta, Nb, Zr, 및 희토류 등을 복합적으로 함유한 복합광을 대상으로 사염화탄소에 의한 염화반응을 알아보기 위한 기초연구로서 각 산화물의 염화반응 특성을 알아보고 이를 토대로 복합광의 염화반응을 비교하여 보았다. 실험결과 산화물 상태의 Nb, Ta 및 Zr은 비교적 낮은 온도에서 염화반응이 일어나고 염화물이 휘발됨을 알 수 있었다. 복합광을 반응 온도 $400^{\circ}C,\;CCl_4$ 분압 0.28 일때 반응시간이 10분에서 60분으로 변함에 따라 니오븀 및 탄탈륨은 $91%{\sim}99%$의 높은 회수율을 나타내었으나 지르코늄은 각각 16.5%에서 27.5%로 약간 증가하는 경향을 나타내었다. 희토류의 경우 세륨은 반응율이 71.7에서 73% 정도였고 란타늄은 51%에서 54% 정도의 반응율을 나타내었다.

• Journal of the Korean Ceramic Society
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• v.30 no.7
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• pp.563-570
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• 1993

Spherical, monosized gadolinium compound was prepared by the reaction of Gd(NO3)3 solution with decomposition products of urea in the solution at evaluated temperature. Chemical composition and calcination characteristics of spherical gadolinium compound prepared were investigated by X-ray IR and TG-DTA. The approximate chemical composition of the spherical particle precipitated was Gd(OH)CO3.1.5H2O. Gd(OH)CO3.1.5H2O was calcined to monoclinic type Gd2O3 at 115$0^{\circ}C$ via cubic type Gd2O3 near $600^{\circ}C$. The effects of various parameters such as pH, temperature, concentration ratio of urea to gadolinium precusor, ageing time, and others material (CCl3COOH and HOCNH2) in stead of urea as precipitating agent on the properties of the resulting precipitates were studied systematically.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.5
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• pp.1375-1378
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• 2005

Sequiterpene lactone (1) has determined by spectroscopic analysis. This compound (1) inhibited the growth of the dermatophytic fungus Trichophyton mentagrophytes (ATCC 28185, 2 mm zone at $15{\mu}g/disk$), cytotoxic to murine leukaemia cell lines ATCC CCL 46 P388Dl, ($IC_{50}$ 1,125 ng/mL at $7.5{\mu}g/disk$) and BSC monkey kidney cell lines (100% of well at $15{\mu}g/disk$).

• Journal of the Korean institute of surface engineering
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• v.5 no.1
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• pp.1-7
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• 1972

Copper -clad laminate(CCL) was fabricated and evaluated by bonding 35${\pm}$5${\mu}$ thick electroplated copper foils with a suitable adhesive to an insulating base such as phenolic resin laminate. In this study, electroplating methods and conditions were studied to produced good quality copper foils for printed circuit board applications. The electroplating bath solutions used were a copper-sulfate solution and a concentrated copper fluoborate solution. A surface roughening treatment that improved the adhesive strength of copper foils with an insulating laminate was also developed . A conventional copper sulfate solution containing sulfuric acid was used for the roughening treatment.

• Journal of Environmental Health Sciences
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• v.33 no.3
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• pp.202-206
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• 2007

Petasites japonicus (Compositae) is a perennial herb which has been used as treatment of antitussive, expectorant, sedatives, paralysis, diurectics in folk remedies. The pharmacological studies of this natural drug have not yet estabilished. So, we examined anti-lipid peroxidative effects and liver protective effect on $CCl_4$ induced lipid peroxidation and hepatotoxicity in rats. In vivo liver lipid, MeOH Ex. revealed significant increase of anti-lipid peroxidative effects according to concentration dependently. In chemical parameters obtained from serum analysis, MeOH Ex. as a increase of medicine concentration (0.25 g/kg, 0.5 g/kg, 1.0 g/kg), GOT, GPT, AlP decreased. In 0.5 g/kg GPT administered group, there was relative in GOT, AlP. Cholesterol decreased in 1.0 g/kg and 1.0 g/kg administered group, BUN decreased relatively in 1.0 g/kg administered group.

• YAKHAK HOEJI
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• v.35 no.5
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• pp.384-388
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• 1991

To explore the effect of monosodium-L-glutamate(MSG) on CCI$_{4}$-damaged liver in Wister male rat, 5% MSG solution as drink water were administered after S.C. injection of 0.1 mg/kg CC1$_{4}$ twice a week for 4 weeks. After last administration of MSG, heptic glutathione(GSH) dependent system was assayed. It showed that MSG increased significanly hepatic glutathione(GSH) and glutathione peroxidase(GSH$_{px}$), but decreased glutathione-S-transferase(GST) acivity in normal rats. MSG increased significantly the GSH$_{px}$ and GST activities in rats with CCI$_{4}$-induced liver damage. These results indicate that decrease of GSH dependent systems in CC1$_{4}$ liver injury might be partially elevated by coadministration of MSG.

• Korean journal of food and cookery science
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• v.2 no.2
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• pp.16-20
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• 1986

The major pungent component from Korean radish roots was purified by reverse phase high performance liquid chromatography (RPHPLC), and characterized as 4-methylthio-3-butenyl isothiocyanate on the basis of the sensory test (pungency), UV spectrum and mass spectrum analysis. The purified isothiocyanate moved as a single peak(retention time, 5.2 min) in RP-HPLC analysis, and as a single spot(Rf, 0.9) in TLC analysis.

• Bulletin of the Korean Chemical Society
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• v.17 no.2
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• pp.128-131
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• 1996

From Raman spectra, the ${\nu}g$C=O frequencies of 4-substituted benzaldehydes were found to correlate with the ${\sigma}_p$ values of the 4-x atom or group as well as the acceptor number (AN) values of solvents. In various solvents, the ${\nu}g$C=O frequency of benzaldehyde decreased upon the increase of benzaldehyde concentration. This shift was mainly due to the hydrogen bonding between the carbonyl oxygen and/or aldehydic proton of benzaldehyde and the solvent molecules. Over the 1-80 volume % change, the ${\nu}g$C=O frequency of benzaldehyde down shifted from 1709.4 $cm^{-1}$ to 1700.2 $cm^{-1}$ in CCl4 solution and from 1703.0 $cm^{-1}$ to 1698.0 $cm^{-1}$ in $C_2H_5OH$ solution. This is due to the fact that hydrogen bonding between the benzaldehyde and C2H5OH was much stronger than that between the benzaldehyde and the other solvents.