[KSCI] Korea Science Citation Index Service

Isolation and Biological Activity of Sesquiterpene Lactone

Kim Myung-Ju (Department of Skin & Beauty, Kwangju Health Science College, Honam University)
Oh Hyun-Ju (Department of Beauty & Art, Honam University)
Baek Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.19, no.5, 2005 , pp. 1375-1378 More about this Journal

Abstract

Sequiterpene lactone (1) has determined by spectroscopic analysis. This compound (1) inhibited the growth of the dermatophytic fungus Trichophyton mentagrophytes (ATCC 28185, 2 mm zone at $15{\mu}g/disk$ ), cytotoxic to murine leukaemia cell lines ATCC CCL 46 P388Dl, ( $IC_{50}$ 1,125 ng/mL at $7.5{\mu}g/disk$ ) and BSC monkey kidney cell lines (100% of well at $15{\mu}g/disk$ ).

Keywords

Sequiterpene lactone (1); Trichophyton mentagrophytes; P388; Cytotoxic activity;

Citations & Related Records

Reference

1	In vitro Biological Activity of Germacranolide sesquiterpene lactones / [Kim, Myung-Ju;Lee, Jae-Sug;Baek, Seung-Hwa;] / Advances in Traditional Medicine
2	In vitro cytotoxic activity of (-)-ent-costunolide (Notes) / [Kim, Myung-Ju;Lee, Jae-Sug;Baek, Seung-Hwa;] / Advances in Traditional Medicine