• Title/Summary/Keyword: Biological aerosol

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Development of Humidity Sensor Based on Ceramic/Metal Halide Composite Films for Non-Contact Biological Signal Monitoring Applications (비접촉 생체신호 모니터링 응용을 위한 세라믹/메탈 할라이드 복합막 기반 습도센서 개발)

  • Park, Tae-Ung;Kim, Ik-Soo;Kim, Min-Ji;Park, Chulhwan;Seo, Eui-kyoung;Oh, Jong-Min
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.35 no.4
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    • pp.412-417
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    • 2022
  • Capacitive-type humidity sensors with a high sensitivity and fast response/recovery times have attracted a great attention in non-contact respiration biological signal monitoring applications. However, complicated fabrication processes involving high-temperature heat treatment for the hygroscopic film is essential in the conventional ceramic-based humidity sensors. In this study, a non-toxic ceramic/metal halide (BaTiO3(BT)/NaCl) humidity sensor was prepared at room temperature using a solvent-free aerosol deposition process (AD) without any additional process. Currently prepared BT/NaCl humidity sensor shows an excellent sensitivity (245 pF/RH%) and superior response/recovery times (3s/4s) due to the NaCl ionization effect resulting in an immense interfacial polarization. Furthermore, the non-contact respiration signal variation using the BT/NaCl sensor was determined to be over 700% by maintaining the distance of 20 cm between the individual and the sensor. Through the AD-fabricated sensor in this study, we expect to develop a non-contact biological signal monitoring system that can be applied to various fields such as respiratory disease detection and management, infant respiratory signal observation, and touchless skin moisture sensing button.

Simulation of Plume Length Induced by Orimulsion Combustion (오리멀젼 연소시 발생하는 백연의 연기거리 전산모사)

  • Kwak, Byoung-Kyu;Kim, Jong-Ho;Joo, Ji-Bong;Lee, Jeong-Jin;Kim, Jin-Soo;Kim, Young-Hun;Yi, Jong-Heop
    • Clean Technology
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    • v.14 no.2
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    • pp.136-143
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    • 2008
  • The objective of this study is to investigate the visibility of plume at the Y power plant stack, which fires the orimulsion as a fuel. The plume contains numerous primary particles under $1\;{\mu}m$ size and inorganic ions possibly inferred by the chemicals of secondary aerosol formation. We evaluated the visibility of the plume using the modified PLUVUE-II model. The monitoring data on the particle size distribution (PSD) and secondary aerosols of sulfate were applied to estimate and evaluate the main factors of plume opacity. The chemical reactions were applied to the model for the secondary aerosol formation of $(NH_4)_2SO_4(s)$. The maximum plume length was estimated by an optic method using threshold contrast. The results showed that the plume length was strongly dependent upon the PSD and $(NH_4)_2SO_4(s)$ concentration of the plume emitted from the stack.

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Filtration Efficiencies of Commercial Face Masks in Korea for Biological Aerosols (국내 출시 마스크의 바이오에어로졸 여과효율 평가)

  • Choi, Sueun;Choi, Doseon;Jang, Sung Jae;Park, SungJun;Yoon, Chungsik;Lee, Kiyoung;Ko, GwangPyo;Lee, Cheonghoon
    • Journal of Environmental Health Sciences
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    • v.48 no.2
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    • pp.116-122
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    • 2022
  • Background: The recent COVID-19 pandemic is one of the worst disease outbreaks of the 21th century. Due to a lack of reliable antiviral therapeutics, wearing face masks is recommended to prevent airborne infection originating from virus-contaminated bioaerosols. Objectives: The aim of this study was to evaluate the filtration efficiencies of face masks that are commercially available in South Korea for a biological aerosol of Staphylococcus aureus (S. aureus) and murine coronavirus, a well-known surrogate for human coronaviruses. Methods: We collected six different kinds of commercial masks: two Korea Filter (KF)94 (KF94-1, KF94-2) masks, one surgical (Surgical-1) mask, one anti-droplet (KF-AD-1) mask, and two dust (Dust-1, Dust-2) face masks. S. aureus (ATCC 6538), a well-performing test bacteria and murine coronavirus (ATCC VR-764) were prepared under a suitable culture condition. Then, a mask biological filtration tester was used to examine the microbial filtration efficiencies of masks. Test microorganisms were quantitatively measured via cultivation methods and microbial filtration efficiencies were calculated appropriately. Results: All face masks showed over 99.6% filtration efficiency for S. aureus or murine coronavirus. There were no significant differences among the bacterial filtration efficiencies of the face masks. KF94-1 (99.97±0.08%) and Dust-1 mask (99.97±0.07%) showed the highest (over 99.9%) filtration efficiency for murine coronavirus. KF94-1 or Dust-1 masks showed a significant virus filtration efficiency compared to Surgical-1 mask (p<0.05; Mann-Whitney U test). Conclusions: All the commercially available face masks used in this study can filter S. aureus or murine coronavirus in bioaerosols efficiently, regardless of the mask type. Therefore, our results suggest that wearing a certified face mask is a reliable means to prevent the transmission of infectious airborne diseases via biological aerosols.

Preparation of Poly(N-vinyl-2-pyrrolidone) Microparticles Using Supercritical Anti-solvent (초임계 반용매법을 이용한 폴리비닐피롤리돈 미세입자의 제조)

  • Shin, Moon-Sam;Kim, Hwa-Yong
    • Clean Technology
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    • v.14 no.4
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    • pp.242-247
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    • 2008
  • Poly(N-vinyl-2-pyrrolidone) (PVP) has been used as biocompatible and biodegradable polymer in cosmetics, pharmaceuticals and electronics. Micro-particles of PVP were produced using an aerosol solvent extraction system (ASES). Dichloromethane (DCM) and supercritical carbon dioxide were used as solvent and antisolvent, respectively. The mean diameter of the obtained polymer particles ranged from 0.184 to $0.249\;{\mu}m$. The relationship between particle size and initial drop size was also considered.

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Morphological control and electrostatic deposition of silver nanoparticles produced by condensation-evaporation method (증발-응축법에 의해 발생된 은(silver) 나노입자의 구조제어 및 전기적 부착 특성 연구)

  • Kim, Whidong;Ahn, Ji Young;Kim, Soo Hyung
    • Particle and aerosol research
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    • v.5 no.2
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    • pp.83-90
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    • 2009
  • This paper describes a condensation-evaporation method (CEM) to produce size-controlled spherical silver nanoparticles by perturbing coagulation and coalescence processes in the gas phase. Polydisperse silver nanoparticles generated by the CEM were first introduced into a differential mobility analyzer (DMA) to select a group of silver nanoparticles with same electrical mobility, which also enables to make a group of nanoparticles with elongated structures and same projected area. These silver nanoparticles selected by the DMA were then in-situ sintered at ${\sim}600^{\circ}C$, and then they were observed to turn into spherical shaped nanoparticles by the rapid coalescence process. With the assistance of modified converging-typed quartz reactor, we can also produce the 10 times higher number concentration of silver nanoparticles compared with a general quartz reactor with uniform diameter. Finally, the spherical silver nanoparticles with 30 nm were electrostatically deposited on the surface of silicon substrate with the coverage rate of ~4%/hr. This useful preparation method of size-controlled monodisperse silver nanoparticles developed in this work can be applied to the various studies for characterizing the physical, chemical, optical, and biological properties of nanoparticles as a function of their size.

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Composition and Use of Biosafety Level 3 Facility (생물안전 3등급 연구시설의 구성 및 이용)

  • Kim, Changhwan;Hur, Gyeunghaeng;Lee, Wangeol;Jung, Seongtae
    • Journal of the Korea Institute of Military Science and Technology
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    • v.18 no.3
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    • pp.335-342
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    • 2015
  • Laboratory facilities for biology are designed as biosafety level 1, biosafety level 2, biosafety level 3, and biosafety level 4. Biosafety level designations are based on a composite of the design features, construction, containment facilities, equipment, practice and operation procedures required for working with agents from the various risk groups. Generally, biosafety level 3 means the facility that is appropriate for the experiments using pathogens which can cause serious diseases by aerosol transmission. The biosafety level assigned for the specific work to be done is driven by professional judgement based on a risk assessment, rather than by automatic assignment according to the particular risk group designation of the pathogenic agents to be used. In this paper, we introduced the biosafety level 3 facility operated in ADD(Agency for defense development). It contains the overview of facility, microbiological experiment, animal experiment, decontamination and waste disposal. Biosafety level 3 laboratory in ADD has served the vital role in the research of biological agents and antidote development.

Efficiency test Evaluation Method for Nebulizer & Medicinal Nonventilatory Nebulizer (의료용 흡입기 및 분무기의 성능 평가 연구)

  • Kim, S.M.;Jeong, J.H.;Lee, J.H.;Rho, S.G.
    • Journal of Biomedical Engineering Research
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    • v.30 no.5
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    • pp.438-443
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    • 2009
  • Nebulizer is designed to atomize medicinal fluid for patient with small particles(0.5-$5{\mu}m$) and also able to deliver particles from devices to the lungs when patient inhales air. Several particle size measurements are currently used to size aerosol particles. The most commonly used test is the cascade impactor method in as a standard. But, other methods for comparative particle size distribution data such as the particle size range and reproducibility are acceptable. Therefore, in this study a new test methode is suggested for nonventilatory nebulizer evaluation equipment.

Control Methods for Aerosols and Airborne Spreading Theory of SARS-CoV-2 (사스-코로나바이러스-2 공기 중 부유 전파이론과 에어로졸 제어기술)

  • Lee, Byung Uk
    • Journal of Environmental Health Sciences
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    • v.47 no.2
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    • pp.123-130
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    • 2021
  • Objectives: Control methods against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosols have been introduced. Airborne spreading theories for SARS-CoV-2 were analyzed in this study. Methods: Control methods for airborne microorganisms were discussed. Studies on theoretical estimations for airborne spreading of SARS-CoV-2 were presented and analyzed. Analytic calculations were conducted for explaining control techniques for airborne microorganisms. Results: Control methods for SARS-CoV-2 aerosols can include physical or biological procedures. Characterization of SARS-CoV-2 aerosols and massive clustering infection cases of COVID-19 support the airborne spreading theories of SARS-CoV-2. It is necessary to consider the disadvantages of control methods for airborne microorganisms. Conclusions: A study on control methods against bioaerosols is necessary to prevent the spreading of viruses. Airborne spreading theories of SARS-CoV-2 were supported by the current evidence, but further studies are needed to confirm these theories.

Promises and Risks of Unsaturated Volatile Organic Compounds: Limonene, Pinene, and Isoprene

  • Jin, Kyong-Suk;Jun, Mi-Ra;Park, Min-Ji;Ok, Seon;Jeong, Jae-Han;Kang, Hye-Sook;Jo, Wan-Keun;Lim, Ho-Jin;Jeong, Woo-Sik
    • Food Science and Biotechnology
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    • v.17 no.3
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    • pp.447-456
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    • 2008
  • Limonene, pinene, and isoprene are abundant and ubiquitous volatile organic compounds (VOCs) which are found in various natural products and also produced from various manufacture processes. Limonene and pinene are major components of food additives and household products for enrichment of good flavors and elimination of malodors, and isoprene is a basal motif of monoterpenes such as limonene and pinene. They have shown many beneficial effects such as chemopreventive, chemotherapeutic, and antioxidant activities. Upon certain conditions, however, adverse effects of these compounds on human health have also been reported. Although they do not seem to have acute and severe toxicity to human, they can easily generate secondary organic aerosols (SOAs) when they react with oxygen and/or ozone, which have shown certain toxic effects on experimental animal models as well as on humans. Numerous household and scented products containing limonene, pinene, and isoprene are widely used in these days. However, biological consequences upon exposure to these products are largely unknown. The aim of this review is to summarize and analyze the current understanding on the biological effects of VOCs, in particular limonene, pinene, and isoprene, as well as their SOAs.

Numerical Analysis on the Flow Characteristics Considering the Inspiratory Flow Rate in a Human Airway (수치해석 기법을 이용한 호흡 유량에 따른 사람의 기도 내 유동 특성 연구)

  • Sung, Kun Hyuk;Ryou, Hong Sun
    • Journal of Biomedical Engineering Research
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    • v.33 no.4
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    • pp.177-183
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    • 2012
  • The inspiratory flow rate of a human is changed with the amount of the workload. The flow characteristic is affected by the inspiratory flow rate. In the flow field of airway, the both of turbulence intensity and secondary flow affect the deposition pattern of particles which is important for the drug-aerosol targeting. Thus the analysis of the flow characteristic in a human airway is important. The purpose of this study is to investigate the effects of the inspiratory flow rate on the flow characteristics in a human airway. The tubular airway is consistent with the oral cavity, pharynx, larynx and trachea. The relatively inspiratory flow rate is used at each case of human states regarding the workload. By the effect of geometric airway changes, transition to turbulent airflow after the larynx can occur with relaminarization further downstream. The low Reynolds number k-${\omega}$ turbulence model is used for analysis with flow regime. As the inspiratory flow rate is larger, the turbulence kinetic energy and secondary flow intensity increase in airway. On the other hand, the area of recirculation zone is smaller.