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Composition and Use of Biosafety Level 3 Facility

생물안전 3등급 연구시설의 구성 및 이용

  • Kim, Changhwan (The 5th Research and Development Institute, Agency for Defense Development) ;
  • Hur, Gyeunghaeng (The 5th Research and Development Institute, Agency for Defense Development) ;
  • Lee, Wangeol (The 5th Research and Development Institute, Agency for Defense Development) ;
  • Jung, Seongtae (The 5th Research and Development Institute, Agency for Defense Development)
  • 김창환 (국방과학연구소 제5기술연구본부) ;
  • 허경행 (국방과학연구소 제5기술연구본부) ;
  • 이완걸 (국방과학연구소 제5기술연구본부) ;
  • 정성태 (국방과학연구소 제5기술연구본부)
  • Received : 2014.10.06
  • Accepted : 2015.05.22
  • Published : 2015.06.05

Abstract

Laboratory facilities for biology are designed as biosafety level 1, biosafety level 2, biosafety level 3, and biosafety level 4. Biosafety level designations are based on a composite of the design features, construction, containment facilities, equipment, practice and operation procedures required for working with agents from the various risk groups. Generally, biosafety level 3 means the facility that is appropriate for the experiments using pathogens which can cause serious diseases by aerosol transmission. The biosafety level assigned for the specific work to be done is driven by professional judgement based on a risk assessment, rather than by automatic assignment according to the particular risk group designation of the pathogenic agents to be used. In this paper, we introduced the biosafety level 3 facility operated in ADD(Agency for defense development). It contains the overview of facility, microbiological experiment, animal experiment, decontamination and waste disposal. Biosafety level 3 laboratory in ADD has served the vital role in the research of biological agents and antidote development.

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References

  1. Health Canada, "The Laboratory Safety Guidelines (3rd edition) 2004.
  2. World Health Organization, Laboratory Biosafety Manual(3rd edition), 2004.
  3. Korea Center for Disease Control, "Guideline for Laboratory Biosafety," 2008.
  4. Korea Center for Disease Control, "Safety Guideline for Biosafety Level 3 Facility," 2008.
  5. Korea Center for Disease Control, "Validation of Biosafety Level 3 Facility," 2013.