• 한국임상수의학회지
• /
• 제28권6호
• /
• pp.603-606
• /
• 2011

11년 령의 중성화된 수컷 코커 스파니엘견이 구취, 식욕부진과 좌측 안면부의 부종 증상을 보여 내원하였다. 신체 검사 상에서 좌측 구강점막의 단단한 종괴가 확인되었다. 가는 침 흡인 세포검사 결과 악성의 중간엽 유래 종양이 가장 의심되어 생검을 실시하였고 조직검사 결과 섬유육종으로 진단되었다. 보호자의 거부로 수술적인 치료가 아닌 카보플라틴 (carboplatin, 300 $mg/m^2$, IV, q 21 days)을 이용한 항암치료를 실시하였다. 항암치료 시작 후 육안적으로 종양의 크기가 현저히 줄어들어 약 89일 후에는 육안적으로 완전 경감되었다. 총 4회의 항암치료 이후 항암치료를 중단하였고 종양의 재발은 일어나지 않았다. 본 증례보고는 개의 구강 섬유육종에서 carboplatin을 이용한 항암 치료가 육안적인 종양의 완전 경감을 유도할 수 있음을 보여준다.

• 한국의학물리학회:학술대회논문집
• /
• 한국의학물리학회 2002년도 Proceedings
• /
• pp.17-18
• /
• 2002

Last year, a three-year research program was started in order to establish an external audit system to radiotherapy QA in Japan. It consists of questionnaire surveys, mailed (off-site) dosimetry and visited (on-site) dosimetry at radiotherapy facilities in Japan. The first questionnaire was sent to all Japanese radiotherapy facilities in October 2001, surveying basic QA procedures at each facility. 628 answers were returned with the return rate of 87%. In February 2002, the second questionnaire was sent. Off-site and on-site dosimetry have been tested in several facilities, and will be started soon. We anticipates that this program will gradually grow to a radiotherapy quality control center similar to Radiological Physics Center at MD Anderson Hospital.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1995년도 하계학술대회 논문집 A
• /
• pp.451-454
• /
• 1995

Increasing the transfortation efficiency is very important issue in railway system. Speed-up of train and shortage of headway can be its solution. Headway can vary with blocksection length, characteristics of the railway and signalling systems. Safety braking distance needed for passenger's safety is very important factor in block section division method. In this study, basic block section division program was developed with the differential ratio of braking distance resulted by grade value of the track. More complete block section division program is going to be developed by the help of experienced experts.

• 한국임상보건과학회지
• /
• 제10권2호
• /
• pp.1600-1606
• /
• 2022

Objective: This study was to compares and analyzes programs applied to improve cognitive function in patients with mild cognitive impairment and early dementia in the community to find out their effectiveness. Methods: In this study, 12 papers were finalized by searching for "elderly", "cognitive", "community", and "program" using the database of the Research Information System (RISS), National Assembly Library, and Korean Studies Information (KISS). Results: Programs for cognitive function were in the order of cognitive stimulation program, arts and crafts, and exercise program. In the program, rather than applying the cognitive stimulation program alone, the program was operated by combining leisure or exercise, music, art, and handicraft. The time was shown to be 30 minutes. The most frequently used evaluation tool was MMSE, followed by GDS and BBS. By cognitive domain, cognitive stimulation program and memory, satisfaction in psychology, and balance ability in exercise were evaluated the most. In the cognitive area, various cognitive stimulation areas were included, and in the exercise area, basic exercise, muscle strength exercise, joint exercise, and balance exercise were applied. Conclusion: Therefore, developing a program to improve cognitive function for mild cognitive impairment, it will be possible to prepare guidelines to establish and development.

• 정보교육학회논문지
• /
• 제21권3호
• /
• pp.351-360
• /
• 2017

본 연구는 디자인 사고를 적용한 SW교육이 초등학교 예비교사의 창의성에 미치는 효과를 분석하였다. 제주 소재 한 대학교 초등컴퓨터교육 강좌를 신청한 학부 1학년 22명의 초등학교 예비교사들을 대상으로 연구를 실시하였다. 연구대상인 예비교사들은 SW교육에 대한 기본적인 이해를 하지 못하고 있을 뿐만 아니라 연구에 사용할 EPL 도구인 스크래치 프로그램에 대한 기초적인 지식을 갖추지 못하였다. 따라서 창의성 사전검사 이전에 18차시에 걸쳐 SW교육에 대한 기본 교육과 스크래치 프로그램의 기본 기능을 학습하는 시간을 가졌다. 창의성 사전검사를 실시하고 21시간에 걸쳐 디자인 사고를 적용한 SW교육을 진행한 후 창의성 사후검사를 실시하였다. 창의성 검사도구로는 Torrance의 TTCT 도형 검사지 A, B형을 사용하여 분석하였다. 검증 결과, 디자인 사고를 적용한 SW교육이 초등학교 예비교사들의 창의성 향상에 효과적인 것으로 나타났다.

• 현장농수산연구지
• /
• 제11권1호
• /
• pp.21-33
• /
• 2009

The agricultural tourism is something that urban people can have an experience of the traditional culture and knowledge of the agriculture, so that it result the improvement of the agricultural profit and keep the special agricultural system. Recently, the demand of the agricultural tourism was increasing, but it was not really enough today that the practice of the tourism for essential farm experience or physical plan. The experiments were practiced by a land in Sucheong-li, Namjong-myun, Gwangju-si, Gyeonggi-do which provides the program for the basic plan and management of the experiential farm, so it shows a developmental model of that typical farm. The basic design of developmental model was formed by the analysis of the natural, civilized and visual environments. The site plan for the experiential farm was composed of a parking lot, public facilities, resting place, experiential site, sports facilities and pedestrian space. There was an examination that the activation of experiential farm should change the concept of the big production or labor-focused farm from a tourism-focused form.

• Molecules and Cells
• /
• 제25권4호
• /
• pp.559-565
• /
• 2008

Members of the TGA family of basic domain/leucine zipper transcription factors regulate defense genes through physical interaction with NON-EXPRESSOR OF PR1 (NPR1). Of the seven TGA family members, TGA4/octopine synthase (ocs)-element-binding factor 4 (OBF4) is the least understood. Here we present evidence for a novel function of OBF4 as a regulator of flowering. We identified CONSTANS (CO), a positive regulator of floral induction, as an OBF4-interacting protein, in a yeast two-hybrid library screen. OBF4 interacts with the B-box region of CO. The abundance of OBF4 mRNA cycles with a 24 h rhythm under both long-day (LD) and short-day (SD) conditions, with significantly higher levels during the night than during the day. Electrophoretic mobility shift assays revealed that OBF4 binds to the promoter of the FLOWERING LOCUS T (FT) gene, a direct target of CO. We also found that, like CO and FT, an OBF4:GUS construct was prominently expressed in the vascular tissues of leaf, indicating that OBF4 can regulate FT expression through the formation of a protein complex with CO. Taken together, our results suggest that OBF4 may act as a link between defense responses and flowering.

• Journal of Korean Biological Nursing Science
• /
• 제19권3호
• /
• pp.141-150
• /
• 2017

Purpose: The purpose of this study was to investigate the effects of the Korean Dietary Approaches to Stop Hypertension (DASH) education program on oxidative stress, antioxidant capacity, and serum homocysteine (Hcy) level in elderly Korean women. Methods: This was a quasi-experimental study employing non-equivalent control group pretest-posttest design. The DASH group (n= 27) underwent the DASH education program for 12 weeks, whereas the control group (n= 21) was provided one education session. The survey was conducted before and after the intervention period. Results: In DASH group, monounsaturated fatty acid (MUFA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) intakes significantly increased after the intervention as compared to prior to the intervention. No significant differences were found in the control group. After the intervention, thiobarbituric acid reactive substance (TBARS) and Hcy levels significantly decreased in the DASH group but not in the control group. Conclusion: The DASH education program was effective in reducing oxidative stress and Hcy levels in elderly Korean women.

• 공학교육연구
• /
• 제20권4호
• /
• pp.21-27
• /
• 2017

The purpose of this study is to provide basic data and guideline to STEM(Science, Technology, Engineering, Mathematics) educators who prepare engineering education in elementary and secondary school. For this, this study develops a composition model for engineering education program of elementary and secondary school. To do this, a literature research, experts interview and Delphi survey were conducted. Through the literature research, we extracted the components of model for engineering education program of elementary and secondary school and then made a first draft of the model. The draft was revised by experts while Delphi survey was used to validate the model based on Delphi panels' opinions. The panels for the Delphi survey consisted of 51 experts in the STEM education field. The survey was conducted three different times and importance survey was included in the third stage. The conclusions of this study were as follows: First, the model consist of definition, 4 directions, 4 characteristics, 3 educational goals according to school level, educational contents area and element, teaching and learning method and evaluation method. The educational contents area and element consist of 2 major areas, 7 areas and 18 elements. Second, all components of the developed model were valid in most of the statistics such as mean, standard deviation, the degree of consensus and convergence, and CVR(Content Validity Ratio). Third, importance for education contents area and element according to the school level are analyzed.

• 한국도서관정보학회지
• /
• 제39권1호
• /
• pp.219-244
• /
• 2008

이 연구는 현재 실시되고 있는 국내 외 공공도서관의 문화프로그램 현황을 조사, 분석하여 그 결과를 토대로 도서관 문화프로그램의 활성화 방안을 제시하는 데 목적이 있다. 이 연구를 위해 사용한 연구방법은 문헌연구, 설문조사, 사례분석을 주로 실시하였으며, 연구의 타당성 검토와 활성화 방안 모색을 위해 전문가회의도 실시하였다. 본 연구의 결과, 도서관 문화프로그램 활성화 방안으로는 다섯 가지를 제안하였다. (1) 도서관 문화프로그램의 정체성 확립과 국가수준의 독서문화프로그램 개발 및 보급, (2) 특수 공공도서관 및 타 문화 및 교육시설과의 연계 및 협력 프로그램 개발, (3) 지역별 특화 프로그램의 개발, (4) 소외계층 대상별 전문화된 프로그램 개발, (5) 사서의 역량강화가 필요하다.