• Title/Summary/Keyword: Basic Research Program

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Successful Carboplatin Chemotherapy for Oral Fibrosarcoma in the Buccal Mucosa of a Dog (개의 구강점막에 발생한 구강 섬유육종에서 카보플라틴의 성공적인 항암치료 효과)

  • Jung, Dong-In;Kim, Ju-Won;Lim, Chae-Young;Han, Sung-Kuk;Kim, Ha-Jung;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.28 no.6
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    • pp.603-606
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    • 2011
  • An 11-year-old castrated male cocker spaniel presented with halitosis, anorexia, and swelling of the left face. Upon physical examination, a firm mass was detected in the left buccal mucosa. Fine needle aspiration cytology revealed a malignant tumor of mesenchymal origin. We performed biopsy, which gave a diagnosis of oral fibrosarcoma. The client refused surgical treatment, and carboplatin chemotherapy (300 $mg/m^2$, IV, q 21 days) was initiated. The mass gradually decreased in size and disappeared about 89 days after the initial chemotherapy. Complete remission was attained, and the tumor did not relapse. This case report shows that a single carboplatin chemotherapy session can achieve macroscopic complete remission of oral fibrosarcoma.

A new research program that aims to establish an external audit system to radiotherapy QA in Japan

  • Shimbo, Munefumi;Tabushi, Katsuyoshi;Endo, Masahiro;Ikeda, Hiroshi
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.17-18
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    • 2002
  • Last year, a three-year research program was started in order to establish an external audit system to radiotherapy QA in Japan. It consists of questionnaire surveys, mailed (off-site) dosimetry and visited (on-site) dosimetry at radiotherapy facilities in Japan. The first questionnaire was sent to all Japanese radiotherapy facilities in October 2001, surveying basic QA procedures at each facility. 628 answers were returned with the return rate of 87%. In February 2002, the second questionnaire was sent. Off-site and on-site dosimetry have been tested in several facilities, and will be started soon. We anticipates that this program will gradually grow to a radiotherapy quality control center similar to Radiological Physics Center at MD Anderson Hospital.

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Development of Block Section Division Program (폐색구간 설계 프로그램 개발)

  • Ryu, Sang-Hwan;Shin, Hyung-Sup
    • Proceedings of the KIEE Conference
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    • 1995.07a
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    • pp.451-454
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    • 1995
  • Increasing the transfortation efficiency is very important issue in railway system. Speed-up of train and shortage of headway can be its solution. Headway can vary with blocksection length, characteristics of the railway and signalling systems. Safety braking distance needed for passenger's safety is very important factor in block section division method. In this study, basic block section division program was developed with the differential ratio of braking distance resulted by grade value of the track. More complete block section division program is going to be developed by the help of experienced experts.

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Literature Review on the Development of Cognitive Function Improvement Program for the Elderly in Community (지역사회 노인의 인지기능 향상 프로그램 개발에 대한 문헌적 고찰)

  • Lee, Sun-myung;Chae, Joo-Hyun
    • Journal of Korean Clinical Health Science
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    • v.10 no.2
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    • pp.1600-1606
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    • 2022
  • Objective: This study was to compares and analyzes programs applied to improve cognitive function in patients with mild cognitive impairment and early dementia in the community to find out their effectiveness. Methods: In this study, 12 papers were finalized by searching for "elderly", "cognitive", "community", and "program" using the database of the Research Information System (RISS), National Assembly Library, and Korean Studies Information (KISS). Results: Programs for cognitive function were in the order of cognitive stimulation program, arts and crafts, and exercise program. In the program, rather than applying the cognitive stimulation program alone, the program was operated by combining leisure or exercise, music, art, and handicraft. The time was shown to be 30 minutes. The most frequently used evaluation tool was MMSE, followed by GDS and BBS. By cognitive domain, cognitive stimulation program and memory, satisfaction in psychology, and balance ability in exercise were evaluated the most. In the cognitive area, various cognitive stimulation areas were included, and in the exercise area, basic exercise, muscle strength exercise, joint exercise, and balance exercise were applied. Conclusion: Therefore, developing a program to improve cognitive function for mild cognitive impairment, it will be possible to prepare guidelines to establish and development.

The effect of SW education applying Design Thinking on creativity of elementary school pre-service teachers (디자인 사고를 적용한 SW교육이 초등학교 예비교사의 창의성에 미치는 효과)

  • Seo, Youngho;Kim, Jonghoon
    • Journal of The Korean Association of Information Education
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    • v.21 no.3
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    • pp.351-360
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    • 2017
  • The purpose of this study is to analyze the effect of SW education applying design thinking on the creativity of elementary school pre-service teachers. We conducted research on 22 elementary school pre-service teachers who applied for a lecture on elementary computer education at a university in Jeju city. The pre-service teachers who did not have basic understanding of SW education and basic knowledge about scratch program which is an EPL tool for research. Therefore, we had time to learn the basic education of SW education and the basic functions of the scratch program over 18 periods before the pre-test of creativity. After conducting pre-test of creativity and conducting SW education applying design thinking over 21 hours, we conducted post-test of creativity. As a creativity test tool, TTCT pattern test forms A and B of Torrance were used. As a result of the verification, it was found that SW education applying design thinking was effective in improving creativity of elementary school pre-service teachers.

A study of basic developmental model for experiential farm - Case study on the farm of Sucheong Village located in Gyeonggi Province - (농촌체험농장 개발모형 연구 - 수청마을농장을 중심으로 -)

  • Bark, JS;Kwon, Y.H
    • Journal of Practical Agriculture & Fisheries Research
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    • v.11 no.1
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    • pp.21-33
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    • 2009
  • The agricultural tourism is something that urban people can have an experience of the traditional culture and knowledge of the agriculture, so that it result the improvement of the agricultural profit and keep the special agricultural system. Recently, the demand of the agricultural tourism was increasing, but it was not really enough today that the practice of the tourism for essential farm experience or physical plan. The experiments were practiced by a land in Sucheong-li, Namjong-myun, Gwangju-si, Gyeonggi-do which provides the program for the basic plan and management of the experiential farm, so it shows a developmental model of that typical farm. The basic design of developmental model was formed by the analysis of the natural, civilized and visual environments. The site plan for the experiential farm was composed of a parking lot, public facilities, resting place, experiential site, sports facilities and pedestrian space. There was an examination that the activation of experiential farm should change the concept of the big production or labor-focused farm from a tourism-focused form.

Isolation of CONSTANS as a TGA4/OBF4 Interacting Protein

  • Song, Young Hun;Song, Na Young;Shin, Su Young;Kim, Hye Jin;Yun, Dae-Jin;Lim, Chae Oh;Lee, Sang Yeol;Kang, Kyu Young;Hong, Jong Chan
    • Molecules and Cells
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    • v.25 no.4
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    • pp.559-565
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    • 2008
  • Members of the TGA family of basic domain/leucine zipper transcription factors regulate defense genes through physical interaction with NON-EXPRESSOR OF PR1 (NPR1). Of the seven TGA family members, TGA4/octopine synthase (ocs)-element-binding factor 4 (OBF4) is the least understood. Here we present evidence for a novel function of OBF4 as a regulator of flowering. We identified CONSTANS (CO), a positive regulator of floral induction, as an OBF4-interacting protein, in a yeast two-hybrid library screen. OBF4 interacts with the B-box region of CO. The abundance of OBF4 mRNA cycles with a 24 h rhythm under both long-day (LD) and short-day (SD) conditions, with significantly higher levels during the night than during the day. Electrophoretic mobility shift assays revealed that OBF4 binds to the promoter of the FLOWERING LOCUS T (FT) gene, a direct target of CO. We also found that, like CO and FT, an OBF4:GUS construct was prominently expressed in the vascular tissues of leaf, indicating that OBF4 can regulate FT expression through the formation of a protein complex with CO. Taken together, our results suggest that OBF4 may act as a link between defense responses and flowering.

The Effects of Korean DASH Diet Education Program on Oxidative Stress, Antioxidant Capacity, and Serum Homocysteine Level among Elderly Korean Women (한국형 DASH 교육 프로그램이 여성노인의 산화스트레스, 항산화능력과 호모시스테인 농도에 미치는 효과)

  • Choi, Seung-Hye;Choi-Kwon, Smi;Kwak, Chung-Sil;Lee, Haeyoung
    • Journal of Korean Biological Nursing Science
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    • v.19 no.3
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    • pp.141-150
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    • 2017
  • Purpose: The purpose of this study was to investigate the effects of the Korean Dietary Approaches to Stop Hypertension (DASH) education program on oxidative stress, antioxidant capacity, and serum homocysteine (Hcy) level in elderly Korean women. Methods: This was a quasi-experimental study employing non-equivalent control group pretest-posttest design. The DASH group (n= 27) underwent the DASH education program for 12 weeks, whereas the control group (n= 21) was provided one education session. The survey was conducted before and after the intervention period. Results: In DASH group, monounsaturated fatty acid (MUFA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) intakes significantly increased after the intervention as compared to prior to the intervention. No significant differences were found in the control group. After the intervention, thiobarbituric acid reactive substance (TBARS) and Hcy levels significantly decreased in the DASH group but not in the control group. Conclusion: The DASH education program was effective in reducing oxidative stress and Hcy levels in elderly Korean women.

The Development of Composition Model for Engineering Education Program of Elementary and Secondary School (초·중등 공학교육 프로그램 구성 모형 개발)

  • Kim, Young-min;Kim, Ki-soo
    • Journal of Engineering Education Research
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    • v.20 no.4
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    • pp.21-27
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    • 2017
  • The purpose of this study is to provide basic data and guideline to STEM(Science, Technology, Engineering, Mathematics) educators who prepare engineering education in elementary and secondary school. For this, this study develops a composition model for engineering education program of elementary and secondary school. To do this, a literature research, experts interview and Delphi survey were conducted. Through the literature research, we extracted the components of model for engineering education program of elementary and secondary school and then made a first draft of the model. The draft was revised by experts while Delphi survey was used to validate the model based on Delphi panels' opinions. The panels for the Delphi survey consisted of 51 experts in the STEM education field. The survey was conducted three different times and importance survey was included in the third stage. The conclusions of this study were as follows: First, the model consist of definition, 4 directions, 4 characteristics, 3 educational goals according to school level, educational contents area and element, teaching and learning method and evaluation method. The educational contents area and element consist of 2 major areas, 7 areas and 18 elements. Second, all components of the developed model were valid in most of the statistics such as mean, standard deviation, the degree of consensus and convergence, and CVR(Content Validity Ratio). Third, importance for education contents area and element according to the school level are analyzed.

A Study on Analysis and Improvement of Cultural Programs in Public Libraries (공공도서관 문화프로그램 현황 분석과 활성화 방안)

  • Hoang, Gum-Sook;Kim, Soo-Kyoung;Park, Mi-Young
    • Journal of Korean Library and Information Science Society
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    • v.39 no.1
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    • pp.219-244
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    • 2008
  • The Aim of this study lead to facilitating schemes of cultural program in public libraries. In order to present schemes, We analyzed status of operating cultural programs in domestic and outside the country. Research methods are literature investigation, survey and case analysis. As a result of this research, facilitating for cultural programs in public libraries is presented five schemes. We would like to use the result of this research as basic data for supporting policy of cultural program in public libraries.

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