• Journal of Nutrition and Health
• /
• 제28권8호
• /
• pp.771-781
• /
• 1995

The present study was aimed to examine various factors related to serum total cholesterol, triglyceride, atherogenic index, lipoperoxides and vitamin E in 174 middle-aged men residing in Taegu. Body mass index was positively correlated with serum triglyceride, and waist-hip circumference ratio was positively correlated with serum total cholesterol, triglyceride, atherogenic index and vitamin E concentration. Total cholesterol, triglyceride and atherogenic index of the subjects who smoked more than 20 cigarettes per day were significantly higher than those with smoking less or non-smokers. drinking alcohol more than 5 times per week showed higher atherogenic index than drinking less frequently of non-drinking. Subjects doing exercise had higher HDL-cholesterol level than those with no exercise. The intakes of all nutrients were above 90% of RDA and the subjects with good food habit had lower of total cholesterol, triglyceride, atherogenic index and lipoperoxides. The study indicates that avoiding heavy smoking and drinking as well as obesity and keeping regular exercise, good food habit and diversity of foods will reduce risk of cardiovascular diseases in middle-aged men.

• 대한예방한의학회지
• /
• 제10권1호
• /
• pp.67-74
• /
• 2006

Objectives: This study was carried out to establish the normal values of Serum Total Cholesterol, HDL-cholesterol by age and sex for healthy adult and the frequency of dyslipidemia as a risk factor of coronary atherosclerosis. Methods: Total cholesterol, and HDL-cholesterol measured among 14,485 in general growing people (8,712 males and 5,773 females) aged 20 to 69 years and analyzed to use the auto-analyzer Hitach 7600 in enzyme method. Result: 1. The levels of total cholesterol, HDL-cholesterol and atherogenic index were slightly positively correlated with age in both sexes. The mean values of serum lipid profiles were $190{\pm}32.9mg/dl$ in men and $181{\pm}32.8mg/dl$ in women for cholesterol, $50.1{\pm}11.4mg/dl$ in men and $54.5{\pm}12.0mg/dl$ in women for HDL-cholesterol, $3.9{\pm}1.0$ in men and $3.4{\pm}0.8$ in women for atherogenic index. 2. Mean values of total cholesterol and atherogenic index higher in men than in women at the age 20-40 years but significantly higher in women than in men at the age group 60 years.(p<0.001) 3. The frequency of hypercholesterolemia(${\geq}200mg/dl$) and low HDL-cholesterol(<35mg/dl) were increased with age in both sexs, significantly higher in women at the age group 60 years. The frequency of hypercholesterolemia(${\geq}200mg/dl$) and low HDL-cholesterol(<35mg/dl) in men and women was 37.5%, 25.3%, and 5.5%, 2.8%. Their requencies were higher in men than in women. Conclusion: Theses findings suggest that the mean concentrations of total cholesterol and HDL-cholesterol in men and women vary with age. The frequency of hypercholesterolemia(${\geq}200mg/dl$) in men and women was about 31.4% and increased with age.

• 생약학회지
• /
• 제42권1호
• /
• pp.54-60
• /
• 2011

In an attempt to find the activity of Aster glehni (Compositae) leaves on the obesity in vivo, 30% ethanolic extract rich in caffeoylquinic acids was orally treated with 100 and 200 mg/kg for consecutive four weeks during feeding high-fat diet in rats for 6 weeks. This extract prevented the increase of atherogenic index and body weight and oxidative stress from dietinduced obese rats probably due to the pharmacological mechanism of the CQ complex.

• 대한약침학회지
• /
• 제16권3호
• /
• pp.23-29
• /
• 2013

Objectives: Dyslipidemia in diabetes mellitus is a significant risk factor for the development of cardiovascular complications. The aim of this study was to evaluate the effect of the ethyl-acetate fraction of an ethanolic extract from Streospermum suaveolens on lipid metabolism in streptozotocin (STZ)-induced diabetic rats. Methods: Diabetes was induced by intraperitonial injection of STZ (50 mg/kg). Diabetic rats were treated with an ethyl-acetate fraction orally at doses of 200 and 400 mg/kg daily for 14 days. On the $15^{th}$ day, serum lipid profiles, such as total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL), were estimated in experimental rats. The atherogenic (AI) and the coronary risk (CRI) indices were also evaluated. Results: The ethyl-acetate fraction at doses of 200 and 400 mg/kg significantly (P < 0.001) and dose-dependently reduced serum cholesterol, triglycerides and LDL, but increased HDL towards near normal levels as compared to diabetic control rats. The fraction also significantly (P < 0.001) lowered the atherogenic index (AI) and coronary risk index (CAI) in a dose-dependent manner. Conclusion: The present study demonstrated that the ethyl-acetate fraction of Stereospermum suaveolens exhibits a potent antihyperlipidemic activity in hyperglycemic rats and suggests that the plant may have therapeutic value in treating the diabetic complication of hyperlipidemia.

• 동서간호학연구지
• /
• 제10권1호
• /
• pp.41-52
• /
• 2004

Purpose: The purpose of this research was to compare the effects of Danjeon Breathing exercise and walking exercise on blood lipids, physical symptoms and hemoglobin of middle-aged women to determine which of these two exercises was more beneficial. Methods: The Danjeon breathing exercise group(20) took health management counseling and performed an eighty-minute Danjeon breathing exercise three times a week for 12 weeks while the walking exercise group(25) took health management counseling and performed a walking exercise seven hours per week for 12 weeks. The control group(20) received only health management counseling. The groups were homogeneous on age, religion, marital status, education, profession, monthly income per household, menopause, smoking, drinking, fat intake and cholesterol intake. Likewise, the groups were homogeneous on total cholesterol, HDL-cholesterol,atherogenic index, hemoglobin and physical symptoms. The collected data were analyzed by using the SPSS PC program and $x^2$-test, ANOVA, repeated measures of ANOVA and LSD. Results: 1. Total cholesterol of the Danjeon breathing exercise group and the walking exercise group were lower than that of the control group. 2. HDL- cholesterol of the Danjeon breathing exercise group and the walking exercise group were not higher than that of the control group. 3. Atherogenic index of the Danjeon breathing exercise group was lower than that of the control group, but atherogenic index of the walking exercise group was not lower than that of the control group. 4. Hemoglobin of the Danjeon breathing exercise group and the walking exercise group were not higher than that of the control group. 5. Physical symptom score of the Danjeon breathing exercise group was lower than those of the walking exercise group and the control group, but Physical symptom score of the walking exercise group was not lower than that of the control group. Conclusion: Danjeon breathing exercise and walking exercise are effective for decreasing total cholesterol of middle-aged women. Danjeon breathing exercise is more effective for decreasing atherogenic index and physical symptoms of middle-aged women than walking exercise.

• 한국컴퓨터정보학회논문지
• /
• 제27권4호
• /
• pp.193-203
• /
• 2022

본 연구는 앱을 이용한 홈 트레이닝이 비만중년여성의 대사증후군 위험이자 및 동맥경화지수 변화를 분석하여 COVID-19의 펜데믹 시대에 비만 개선의 하나의 중재방법으로 제시하고자 실시되었다. 연구의 대상자는 비만중년여성 33명을 대상으로 앱 홈트레이닝 그룹(AHTG) 15명, 통제그룹 (CG) 18명을 모집하여 8주간의 앱을 이용한 홈트레이닝을 주 3회 실시하였다. 이 연구 결과 AHTG의 대사증후군 위험요인 중 WC(p<.001)는 유의하게 감소하고 HDL-C(p<.05)는 유의하게 증가하였으며, 동맥경화지수는 LDL-C/HDL-C(p<.01) 유의하게 증가하였다. 따라서 COVID-19 펜데믹 시대에 PA는 여러 만성질환에 대한 개선 효과 외에도 심각한 COVID-19 대유행을 완화 하는데 중요한 역할을 하며 앱을 이용한 홈트레이닝이 비만 및 대사증후군을 예방에 효율적인 중재 방법이 될 수 있는 가능성을 확인하였다.

• 한국식품영양학회지
• /
• 제15권4호
• /
• pp.289-294
• /
• 2002

본 연구에서 선발된 17종의 천연물을 Sprague-Dawleyra rat에 급여한 결과, 체중증가, 에너지 소비, fat pads 중량, 간의 triglyceride함량, atherogenic index 그리고 혈중 글루코오스의 함량 등이 감소하는 경향을 나타내었다. 특히 동아를 구강으로 섭취시킨 결과, 체중증가, 에너지 소비, fat pads 중량, 그리고 혈중 글루코오스의 함량 등이 감소하였으나, 간의 triglyceride 함량은 오디와 송엽의 열수 추출물보다 적게 감소하였다. 동아, 오디, 그리고 송엽을 혼합하여 사용한 결과, 각각의 원효를 사용할 경우보다 비만이 개선되는 것으로 나타났다.

• 대한의생명과학회지
• /
• 제23권4호
• /
• pp.321-326
• /
• 2017

Tomatoes are rich in nutrients and have many beneficial advantages on human health. Four cherry tomato supplementation diets (CTSDs) were prepared from the juice and cake of fresh and processed (heat-treated) cherry tomatoes. Rats were fed CTSDs for 28 days and the changes in health indices in the serum were analyzed. CTSDs significantly decreased (P < 0.05) food efficiency ratio compared with the control. CTSD feeding significantly increased (P < 0.05) the high-density lipoprotein cholesterol level compared with the control, which resulted in a significant (P < 0.05) decrease in coronary artery risk index and atherogenic index. Furthermore, CTSD feeding increased serum serotonin level. These results indicate that CTSD shows antihyperlipidemic effect.

• Nutrition Research and Practice
• /
• 제7권6호
• /
• pp.430-438
• /
• 2013

Increased oxidative stress in obese diabetes may have causal effects on diabetic complications, including dyslipidemia. Lipopolysccharides (LPS) along with an atherogenic diet have been found to increase oxidative stress and insulin resistance. Cranberry has been recognized as having beneficial effects on diseases related to oxidative stress. Therefore, we employed obese diabetic animals treated with an atherogenic diet and LPS, with the aim of examining the effects of cranberry powder (CP) on diabetic related metabolic conditions, including lipid profiles, serum insulin and glucose, and biomarkers of oxidative stress. Forty C57BL/KsJ-db/db mice were divided into the following five groups: normal diet + saline, atherogenic diet + saline, atherogenic diet + LPS, atherogenic diet + 5% CP + LPS, and atherogenic diet + 10% CP + LPS. Consumption of an atherogenic diet resulted in elevation of serum total cholesterol and atherogenic index (AI) and reduction of high density lipoprotein (HDL)-cholesterol. However, with 10% CP, the increase in mean HDL-cholesterol level was close to that of the group with a normal diet, whereas AI was maintained at a higher level than that of the group with a normal diet. LPS induced elevated serum insulin level was lowered by greater than 60% with CP (P < 0.05), and mean serum glucose level was reduced by approximately 19% with 5% CP (P > 0.05). Mean activity of liver cytosolic glutathione peroxidase was significantly increased by LPS injection, however it was reduced back to the value without LPS when the diet was fortified with 10% CP (P < 0.05). In groups with CP, a reduction in mean levels of serum protein carbonyl tended to occur in a dose dependent manner. Particularly with 10% CP, a reduction of approximately 89% was observed (P > 0.05). Overall results suggest that fortification of the atherogenic diet with CP may have potential health benefits for obese diabetes with high oxidative stress, by modulation of physical conditions, including some biomarkers of oxidative stress.

• 대한영양사협회학술지
• /
• 제8권3호
• /
• pp.250-259
• /
• 2002

The purpose of this study was to confirm that calcium intake and healthy status play a role in reducing the risk of cardiovascular disease, to assure that calcium intake and regular exercise are important in reducing serum lipid levels in middle-aged women. Daily nutrient intakes were analyzed by convenient method. Anthropometric measurement such as body weight and height and blood pressure were measured. The subjects divided into two groups : women in group I under 50 years of age($\leq$49 yr group) and those in group II 50 years up($\geq$50 yr group). Average ages of group I and II were 43.87 and 53.46 years. The nutrients intake of subjects were higher than Korean recommended dietary allowances(KRDA) except calorie, iron, calcium, vitamin B1. They showed significant difference each other in vitamin B2(p<0.05), calcium(p<0.01) intake. Mean daily calcium intake was 540.88mg in $\leq$49 yr group and 519.50mg in $\geq$50 yr group. The levels of serum cholesterol, triglyceride, blood pressure, Atherogenic Index(AI), LDL/HDL and Cardiac Index(CI) were increased with age. The triglyceride and total cholesterol concentrations and LDL/HDL in $\geq$50 yr group were significantly higher than those of $\leq$49 yr group. There was a highly significantly positive correlation between age and triglyceride, total cholesterol and Atherogenic Index(AI). Triglyceride, total cholesterol, LDL-cholesterol concentration and Atherogenic Index(AI) were positively correlated with body weight and WHR(waist-hip ratio). Also ther was a significantly negative correlation between exercise and Cardiac Index(CI). Also a significantly negative correlation was found between Ca intake and LDL-cholesterol. Exercise and Cardiac Index(CI) also had a significantly negative relation. The results suggest that increased habitual physical activity and calcium intake should be recommended as a way of decreasing blood lipids and blood pressure in middle-aged women.