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http://dx.doi.org/10.15616/BSL.2017.23.4.321

Cherry Tomato Supplementation Reduces Cardiovascular Risk  

Koh, Jong-Ho (Department of Bio-Food Analysis, Bio-campus, Korea Polytechnics College)
Lim, Young-Hee (Department of Public Health Science (BK21 PLUS Program), Graduate School, Korea University)
Hwang, Dahyun (Department of Biomedical Laboratory Science, College of Life and Health Sciences, Hoseo University)
Abstract
Tomatoes are rich in nutrients and have many beneficial advantages on human health. Four cherry tomato supplementation diets (CTSDs) were prepared from the juice and cake of fresh and processed (heat-treated) cherry tomatoes. Rats were fed CTSDs for 28 days and the changes in health indices in the serum were analyzed. CTSDs significantly decreased (P < 0.05) food efficiency ratio compared with the control. CTSD feeding significantly increased (P < 0.05) the high-density lipoprotein cholesterol level compared with the control, which resulted in a significant (P < 0.05) decrease in coronary artery risk index and atherogenic index. Furthermore, CTSD feeding increased serum serotonin level. These results indicate that CTSD shows antihyperlipidemic effect.
Keywords
Cherry tomato; Atherogenic index; Coronary artery risk index; Serotonin;
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1 Alberghina D, Giannetto C, Visser E, Ellis A. Effect of diet on plasma tryptophan and serotonin in trained mares and geldings. Veterinary Record. 2010. 166: 133-136.   DOI
2 Berrougui H, Momo CN, Khalil A. Health benefits of high-density lipoproteins in preventing cardiovascular diseases. Journal of Clinical Lipidology. 2012. 6: 524-533.   DOI
3 Bornet F, Brouns F, Tashiro Y, Duvillier V. Nutritional aspects of short-chain fructooligosaccharides: natural occurrence, chemistry, physiology and health implications. Digestive and Liver Disease. 2002. 34: S111-S120.   DOI
4 Cunniff P. AOAC international: Gaithersburg. 1997.
5 Abbott RD, Wilson PW, Kannel WB, Castelli WP. High density lipoprotein cholesterol, total cholesterol screening, and myocardial infarction. The Framingham study. Arteriosclerosis, Thrombosis, and Vascular Biology. 1988. 8: 207-211.   DOI
6 Adeneye AA, Adeyemi OO, Agbaje EO. Anti-obesity and antihyperlipidaemic effect of hunteria umbellata seed extract in experimental hyperlipidaemia. Journal of Ethnopharmacology. 2010. 130: 307-314.   DOI
7 Duenas M, Hernandez T, Estrella I. Changes in the content of bioactive polyphenolic compounds of lentils by the action of exogenous enzymes. Effect on their antioxidant activity. Food Chemistry. 2007. 101: 90-97.   DOI
8 Fki I, Bouaziz M, Sahnoun Z, Sayadi S. Hypocholesterolemic effects of phenolic-rich extracts of chemlali olive cultivar in rats fed a cholesterol-rich diet. Bioorganic and Medicinal Chemistry. 2005. 13: 5362-5370.   DOI
9 Barter P. The role of HDL-cholesterol in preventing atherosclerotic disease. European Heart Journal Supplements. 2005. 7: F4-F8.   DOI
10 Hokanson JE, Austin MA. Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: A metaanalysis of population-based prospective studies. Journal of Cardiovascular Risk. 1996. 3:213-219.
11 Mackinnon E, Rao A, Josse R, Rao L. Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker n-telopeptide of type i collagen in postmenopausal women. Osteoporosis International. 2011. 22: 1091-1101.   DOI
12 Hussein L, El-Tohamy M. Vitamin a potency of carrot and spinach carotenes in human metabolic studies. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin-und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition. 1990. 60: 229-235.
13 Ilic D, Misso M. Lycopene for the prevention and treatment of benign prostatic hyperplasia and prostate cancer: A systematic review. Maturitas. 2012. 72: 269-276.   DOI
14 Tecott LH, Sun LM, Akana SF, Strack AM, Lowenstein DH, Dallman MF, Julius D. Eating disorder and epilepsy in mice lacking 5-ht2c serotonin receptors. Nature. 1995. 374: 542-546.   DOI
15 Jo SP, Kim JK, Lim YH. Antihyperlipidemic effects of stilbenoids isolated from morus alba in rats fed a high-cholesterol diet. Food and Chemical Toxicology. 2014. 65: 213-218.   DOI
16 Kim KY, Park CW, Kim HM, Kang IC, Jeong HJ. Effects of acanthopanax divaricatus var. Albeofructus in mice submitted to protein restriction. Oriental Pharmacy and Experimental Medicine. 2011. 11: 15-23.   DOI
17 Koh JH, Kim Y, Oh JH. Chemical characterization of tomato juice fermented with bifidobacteria. Journal of Food Science. 2010. 75: 428-432.   DOI
18 Leibowitz SF, Alexander JT. Hypothalamic serotonin in control of eating behavior, meal size, and body weight. Biological Psychiatry. 1998. 44: 851-864.   DOI
19 Nouri MHK, Abad ANA. Comparative study of tomato and tomato paste supplementation on the level of serum lipids and lipoproteins levels in rats fed with high cholesterol. Iranian Red Crescent Medical Journal. 2013. 15: 287.   DOI
20 Sato R, Helzlsouer KJ, Alberg AJ, Hoffman SC, Norkus EP, Comstock GW. Prospective study of carotenoids, tocopherols, and retinoid concentrations and the risk of breast cancer. Cancer Epidemiology and Prevention Biomarkers. 2002. 11:451-457.