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The Extract of Aster glehni Leaves Rich in Caffeoylquinic Acids Prevents Atherogenic Index, Oxidative Stress, and Body Weight Increase in High-Fat Diet-induced Rats  

Kim, Myung-Hoe (Department of Pharmaceutical Engineering, Sangji University)
Nugroho, Agung (Department of Agro-industrial Technology, Lambung Mangkurat University)
Choi, Jong-Won (College of Pharmacy, Kyungsung University)
Park, Hee-Juhn (Department of Pharmaceutical Engineering, Sangji University)
Publication Information
Korean Journal of Pharmacognosy / v.42, no.1, 2011 , pp. 54-60 More about this Journal
Abstract
In an attempt to find the activity of Aster glehni (Compositae) leaves on the obesity in vivo, 30% ethanolic extract rich in caffeoylquinic acids was orally treated with 100 and 200 mg/kg for consecutive four weeks during feeding high-fat diet in rats for 6 weeks. This extract prevented the increase of atherogenic index and body weight and oxidative stress from dietinduced obese rats probably due to the pharmacological mechanism of the CQ complex.
Keywords
Aster glehni; Compositae; Caffeoylquinic acid; High-fat diet; Atherogenic index; Oxidative stress;
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