• Journal of IKEEE
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• v.27 no.4
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• pp.567-572
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• 2023

In this paper, the breakdown voltage of Pi-LDMOS (Partial isolation lateral double diffused metal oxide semiconductor) was analyzed by simulation. Breakdown voltage variation is investigated under various settings of Parial buied oxide(P-BOX) parameters(length, thickness, location) and their mechanism is specified. In addition, the change in on-resistance in the breakdown voltage and trade-off relationship was analyzed according to the change in the P-BOX parameter, and the Figure-of-merit(FOM) was calculated and compared. In proposed structure, Lbox=5 ㎛, tbox=2 ㎛, and Lbc=2 ㎛ showed the highest breakdown voltage of 138V, and Lbox=5 ㎛, tbox=1.6 ㎛, and Lbc=2 ㎛ showed the highest FOM. Compared to conventional LDMOS, the breakdown voltage is 123% and FOM is 3.89 times improved. Therefore, Pi-LDMOS has a high breakdown voltage and FOM, which can contribute to the improvement of the stable operating range of the Power IC.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.2
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• pp.465-470
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• 2010

The charge pump in a phase-locked loop is a key block in determining reference spurs of the VCO output signal. To reduce reference spurs, the current mismatch in the charge pump must be minimized. This paper presents a dual compensation method to reduce the current mismatch. The proposed charge pump and PLL were realized in a $0.18{\mu}m$ CMOS process. Measured current matching characteristics were achieved with less than 1.4% difference and with the current variation of 3.8% in the pump current over the charge pump output voltage range of 0.35-1.35V at 1.8V. The reference spur of the PLL based on the proposed charge pump was measured to be -71dBc.

• Journal of electromagnetic engineering and science
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• v.4 no.3
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• pp.107-112
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• 2004

In this paper, the phase noise of 900 MHz VCO is improved using modified strip line square ring resonator. In order to demonstrate the phase noise improvement of the proposed VCO, the same circuit was manufactured using shorted-circuit resonator. In condition of the same bias current, the phase noise of the proposed VCO with modified square ring resonator is suppressed by 7 dB as - 103 dBc/Hz at 100 kHz offset compared to the conventional VCO with short-circuit resonator. From the proposed VCO, we achieved output power of - 4.8 dBm, harmonics suppression of 16 dB, and tuning bandwidth of 100 MHz. The proposed VCO consumed 5 mA at 3 V, and its size is 1.2 cm ${\times}$ 1.0 cm.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.34D no.10
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• pp.14-23
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• 1997

An MMIC downconverting mixer for cellular phone application has been successfully developed using an MMIC process including $1 \mu\textrm{m}$ ion implanted gaAs MESFET and passive lumped elements consisting of spiral inductor, $Si_3N_4$ MIM capacitor and NiCr resistor. The configuration of the mixer presented in this paper is single-ended dual-gate FET mixer with common-source self-bias circuits for single power supply operation. The dimension of the fabricated circuit is $1.4 mm \times 1.03 mm $ including all input matching circuits and a mixing circuit. The conversion gian and noise figure of the mixer at LO powr of 0 dBm are 5.5dB and 19dB, respectively. The two-tone IM3 characteristics are also measured, showing -60dBc at RF power of -30dBm. Allisolations between each port show better than 20dB.

• BMB Reports
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• v.40 no.1
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• pp.95-99
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• 2007

Bovine coding region single nucleotide polymorphisms located proximal to quantitative trait loci were identified to facilitate bovine QTL fine mapping research. A total of 692,763 bovine SNPs was extracted from 39,432 UniGene clusters, and 53,446 candidate SNPs were found to be a depth >3. In order to validate the in silico SNPs experimentally, 186 animals representing 14 breeds and 100 mixed breeds were analyzed. Genotyping of 40 randomly selected candidate SNPs revealed that 43% of these SNPs ranged in frequency from 0.009 to 0.498. To identify non-synonymous SNPs and to correct for possible frameshift errors in the ESTs at the predicted SNP positions, we designed a program that determines coding regions by protein-sequence referencing, and identified 17,735 nsSNPs. The SNPs and bovine quantitative traits loci informations were integrated into a bovine SNP data: BcSNPdb (http://snugenome.snu.ac.kr/BtcSNP/). Currently there are 43 different kinds of quantitative traits available. Thus, these SNPs would serve as valuable resources for exploiting genomic variation that influence economically and agriculturally important traits in cows.

• Journal of Plant Biotechnology
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• v.29 no.3
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• pp.151-159
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• 2002

Genetic map and molecular marker have a great importance in improving and facilitating crop breeding program as well as in genome analysis and map-based cloning of genes representing desirable characters. This study aimed at developing RAPD markers and constructing a genetic linkage map using 82 BC$_1$F$_1$individuals originated from the cross between '835' and B$_2$in radish (Raphanus sativus L.). One of the parents for genetic linkage map construction, '835'(P$_1$) of egg type is susceptible to Fusarium wilt and have medium resistance to virus infection and the other parent, B$_2$(P$_2$) of round type, is susceptible to Fusarium wilt and virus, Screening of 394 RAPD primers in BC$_1$F$_1$) population resulted in selecting 128 polymorphic markers which displayed 1:1 segregation pattern. Two markers failed to display 1:1 segregation and showed the segregation ratio skewed to maternal genotype. Selected markers were categorized into 14 linkage group based on LOD score represented by MAPMAKER/EXP program. Five groups composed of single marker among them were excluded from the linkage map, and consequently, the remaining groups are well matched with the number of radish chromosome (n＝9). The linkage map constructed with 128 markers covers 1,688.3 cM and the average distance between markers was 13.8 cM. For developing STS marker, we determined the partial nucleotide sequence of OPE10 marker at both ends and designed a oligonucleotide primer pair based on this sequence. STS PCR using the primer pair displayed a single, clear band of which segregation is perfectly matched with that of OPE10 marker. This implies that RAPD markers could readily convert into clear and reliable STS markers.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2003.10a
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• pp.120-120
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• 2003

고능력 젖소와 보통능력 젖소의 번식능력을 비교하기 위하여 progesterone을 분석하여 분만후 초발정일을 추정하였고, 번식자료를 통하여 분만 후 번식성적을 조사하였으며, 또한 비유능력 및 Body condition score(BCS) 에 따른 $PGF_2a + PGF_2a+CIDR$ program 투입 효과를 구명하기 위하여 분만 후 40일째에 $PGF_2a$를 1차 처리한 후 발정이 발현되지 않은 개체에 대하여 1 차 처리후 14일째에 다시 2차 $PGF_2a$를 처리하였고 2차 $PGF_2a$ 처리후에도 발정이 발현되지 않은 개체에 대하여 2차 $PGF_2a$ 처리후 5일째에 CIDR plus를 처리하여 발정유기율을 조사분석하였던 바, 그 결과를 요약하면 다음과 같다. 가. 보통능력우와 고능력우의 분만후 progesterone peak를 나타내는 일수는 각각 $38.8 \pm 11.1$ 및 $39.6 \pm 9.7$일로 거의 비슷한 경향을 나타내었음 나. 보통능력우와 고능력우의 분만후 발정재귀일수는 각각 $99.4 \pm 71.6$ 및 $117 7 \pm 78.6$일로 고능력우에서 18.3일 늦어지는 경향이었음 다 보통능력우와 고능력우의 분만후 수태일수에 있어서 각각 $145.9 \pm 102.8$및 $165.9 \pm 100.8$일로 고능력우에서 20일 늦어지는 경향이었음 라. 보통능력우와 고능력우의 분만간격에 있어서 각각 421.5 \pm 107.2$ 및 $448.4 \pm 108.7$일로 고능력우에서 26.9일 늦어지는 경향을 나타내었음 마 보통능력우와 고능력우에 있어서 1차 $PGF_2a$ 처리시 각각 39.1% 및 60.0%, 2차 $PGF_2a$ 처리시 각각 42.9% 및 70.0%, CIDR plus 처리시 50.0% 및 66.7%의 발정 유기율을 나타내었음 바. BCS에 따라 $PGF_2a + PGF_2a+CIDR$ plus program을 투입한 결과 BCS 2.5 이하와 BCS 2.75-3.50에 있어서 1차 $PGF_2a$ 처리시 각각 47.4% 및 48.3%, 2차 $PGF_2a$ 처리시 각각 40.0% 및 66.7%, CIDR plus 처리시 각 각 50.0% 및 80.0%의 발정 유기율을 나타내었음

• Journal of Electrical Engineering and Technology
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• v.1 no.3
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• pp.396-405
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• 2006

The visual analysis of buried channel (Be) devices such as buried channel MOSFETs and CCDs (Charge Coupled Devices) is investigated to give better understanding and insight for their electrical behaviours using a 3-dimensional (3-D) numerical simulation. This paper clearly demonstrates the capability of the numerical simulation of 'EVEREST' for characterising the analysis of a depletion mode MOSFET and BC CCD, which is a simulation software package of the semiconductor device. The inverse threshold and punch-through voltages obtained from the simulations showed an excellent agreement with those from the measurement involving errors of within approximately 1.8% and 6%, respectively, leading to the channel implanted doping profile of only approximately $4{\sim}5%$ error. For simulation of a buried channel CCD an advanced adaptive discretising technique was used to provide more accurate analysis for the potential barrier height between two channels and depletion depth of a deep depletion CCD, thereby reducing the CPU running time and computer storage requirements. The simulated result for the depletion depth also showed good agreement with the measurement. Thus, the results obtained from this simulation can be employed as the input data of a circuit simulator.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.4089-4093
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• 2016

Purpose: This study aimed to explore the association of ${\beta}-catenin$ expression pattern with pathological response after neoadjuvant chemotherapy in breast cancer (BC) patients. Materials and Methods: In this retrospective exploratory study, data for 50 BC patients who received neoadjuvant chemotherapy were recorded. ${\beta}-catenin$ expression in tumours was assessed using immunohistochemistry and classified as either membranous or cytoplasmic according to the pattern of staining. Distributions of different clinico-pathological parameters according to ${\beta}-catenin$ expression were assessed using the Chi-square test. Logistic regression analysis was used to assess any relation of the pattern of ${\beta}-catenin$ expression with the pathological response. Results: Cytoplasmic ${\beta}-catenin$ expression was detected in 34% of BCs. Among our cases, 52% were hormonal receptor (HR)-positive, 24% were HER2-positive, 74% were clinical stage III and 74% received both anthracycline and taxane-based chemotherapy. Patients with cytoplasmic expression were more commonly younger than 40 years at diagnosis (cytoplasmic, 41.2% vs. no cytoplasmic expression, 12.1%, p=0.03). By doing t-test, cytoplasmic ${\beta}-catenin$ expression was linked with a higher body mass index compared to membranous-only expression ($mean{\pm}SD$ $33.0{\pm}4.47$ vs. $29.6{\pm}6.01$, respectively, p=0.046). No significant associations were found between ${\beta}-catenin$ expression and other parameters such as HR and HER2 status, or clinical stage. Complete pathological response (pCR) rate was twice as great in patients with membranous expression but without statistical significance (membranous-only, 33.3% vs. cytoplasmic, 17.6%, OR= 2.3, 95% CI= 0.55-9.87, p=0.24). Conclusions: This study suggests that cytoplasmic ${\beta}-catenin$ expression may be linked with lower probability of achieving pCR after neoadjuvant chemotherapy. These data need to be validated in a larger cohort of patients.

• Journal of the East Asian Society of Dietary Life
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• v.4 no.1
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• pp.1-18
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• 1994

This study is designed to delve into the measuring systems of different periods so as to help with more exact representations of cultures of different periods. The basis of the measuring system in china stems from the huangjong (Huangzhong : the yellow bell) of the period of Huangdi, the length of the bell being the width of 90 black millet grains. Do (Du : width) ; 1 bun=the width of one black millet grain, 1 Chon=10 Buns, 1 Chuk=10 Chons, 1 Jang=10 Cheoks, 1 In=10 Jangs. Ryang (Lyang : volume) ; 1 Yak=the weight of 1,200 grains in the yellow bell, 1 Hab=2 Yaks, 1Seung=10 habs, 1 Du=10 Seungs, 1 Gok=10 Dus. Hyung (Hung : weight) ; 12 Jus=the weight of 1 Yak, 1Yang=24 Jus are equal 1 Hab in weight, 1 Geun=16 Ryangs, 1 Jo=30 Geuns, 1 Seo=4 Jo. In the era of Eun (In) it was decided that the 9-chon length of the Yellowbell shall be 1 Cheok. The Cheok of Ju was set at 4/5 of the length of the yellow bell. The Cheok of Ju breaks into Yongjocheok, Joryegicheok, Pogeumcheok. Yongjocheok, arising from Rohbancheok of the Ju period, is part of Gokcheok also used as a measuring tool for wooden works. The Han cheok has the same length as the yellow bell. The Sang Cheok is 4/5 of the length of the yellow bell. The Tang Cheok was originally the same as the Sang cheok but became longer and longer to be the Long cheok (31.3cm). The length-measuring system used in the three-nation era of Korea includes the gijeom cheil (35.52cm), Ju cheok (25.45cm), sunje Cheok (23.5cm), the Long Tang Cehok (29.706 cm), making 10 Bun 1 Chon and 10 Chon 1 Cheok. The volume-measuring system(Seung) was 198.81 ㎤ before 681 BC in the shilla Dynasty and was 596.42 ㎤ after that. In the seventh year of Kng Munjong of the Koryo dynasty the standard measuring system with the Long Tang Cheok as its basis was adopted, and the standard volume-measuring tools were used under the name of Migok, Daesodugok, Mijangdu, (29.706 cm), making 10 Bun 1 Chon and 10 Chon 1 Cheok. The volume-measuring system(Seung) was 198.81㎤ before 681 BC in the shilla dynasty and was 596.42 ㎤ after that. In the seventh year of King Munjong of the Koryo dynasty the standard measuring system with the Long Tang Cheok as its basis was adopted, and the standard volume-measuring tools were used under the name of Migok, Daesodugok, Kijangdu, Habseung and gokseok. The 1 Seung volumes of theses toolas were 596,447,927 and 1053㎤, respectively. were called Migok, Daesodugok, Mijangdu, Habseung and Gokseok, being respectively 596,447,927, 1053 ㎤, respectively. In the Chosun Dynasty the length of the Yeongjocheos was 27.6 cm or 31.220 in the Sejong era, 29.8 from Heonjong through Gojong, and 30.3 cm after the 6th year of King Kwangmu, and the volume of Du(Mal) also changed like 4.121 or 5.964, 5.187, 23.08 $\ell$, and the 1-Jeonjung also changed like 2.66 or bout 4, 3.45, 3.75 in line with the changes of the length system.