• Title/Summary/Keyword: 탐색적연구

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An Analysis of the Policy Making Process of Contracting-out of Public Library Appeared in Municipal Ordinance on the Establishment and Operation of Cultural Foundation: Based on the Advocacy Coalition Framework (A시 B구 문화재단 설립 및 운영 조례에 대한 정책결정과정 분석 - 정책옹호연합모형(ACF)을 중심으로 -)

  • Hong, Bohyun;Kim, Giyeong
    • Journal of the Korean Society for Library and Information Science
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    • v.51 no.3
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    • pp.265-292
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    • 2017
  • The purpose of this study is to figure out the movements of policy actors in the policy process of the establishment of a local cultural foundation in B-gu(district), A-si (city), then to explore the way to contract out of the management of public libraries to the cultural foundation in the policy process. Data for the study were collected from various sources from newspapers and assembly minutes to blogs and SNS messages of the policy actors, then analysed based on Advocacy Coalition Framework (ACF). The results showed that 'agreement of contract-out' coalition only accepted public interest of the public libraries between the public interest and specialty of librarianship which were insisted by 'disagreement of contract-out' coalition's policy beliefs. The comparison between this case and a similar policy case showed that the specialty of librarianship as a core belief is effective in changing the beliefs of other coalition. Eventually, it is required to differentiate and to specialize library services among public services in a local area in order to keep the direct management of public libraries by the local government, and this means that everyday library services influence the decision making of library policies in the local area.

Effect of Zanthoxylum piperitum Extract on Human Skin Protection from UVB by Regulation of COP1 and PPAR-α (초피나무 열매 추출물의 COP1 및 PPAR-α 조절을 통한 자외선에 대한 피부 보호 효과)

  • Kim, Yun-Sun;Kim, Yumi;Lee, Sanghwa
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.4
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    • pp.393-401
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    • 2016
  • Ultraviolet (UV) irradiation from the sun is the primary environmental factor that causes skin damages including skin cancer and premature skin aging. Because, even the most powerful sunscreen can't always afford enough protection, it is necessary to enhance the defensive power of skin against UV. Recently, constitutive photomorphogenic protein-1 (COP1) has shown to contribute to the regulation of UVB response of keratinocytes. In this study, we represent that COP1 and its associated protein, de-etiolated 1 (DET1), might participate in photoaging process in human skin as Arabidopsis COP1 does sun-protective function in plants. After UVB irradiation, the decrease of COP1 and DET1 mRNA expression was followed by the increase of c-Jun total protein. Moreover, transfection with DNA vectors expressing COP1 and DET1 down-regulated the c-Jun total protein. We found that Zanthoxylum piperitum extract (ZE) up-regulated the expression of COP1 and DET1 on human keratinocytes, and inhibited the expression of MMP1 which is one of the genes regulated by c-Jun signal. In addition, ZE has been reported to stimulate PPAR-${\alpha}$ and strengthen the skin barrier. We found that ZE decreased the UVB-induced IL-6 and IL-8 in NHEK cells. In human study, ZE protected skin against UV-B induced erythema and erythema-induced pigmentation. These results indicate that ZE could be useful for the protection against the adverse effects of UV irradiation through various mechanisms.

Antimicrobial Effect of Phytochemicals to Listeria monocytogenes Isolated from Slaughterhouses

  • Kim, Hyeji;Oh, Hyemin;Lee, Heeyoung;Kim, Sejeong;Ha, Jimyeong;Lee, Jeeyeon;Choi, Yukyung;Lee, Yewon;Kim, Yujin;Yoon, Yohan;Lee, Soomin
    • Journal of Food Hygiene and Safety
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    • v.33 no.4
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    • pp.255-258
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    • 2018
  • The objective of this study was to investigate the inhibitory effect of natural antimicrobials on Listeria monocytogenes isolated from Korean slaughterhouses. A mixture of 15 strains of L. monocytogenes at low (3 Log CFU/mL) or high (7 Log CFU/mL) concentration was exposed to various extracts (grapefruit seed extract, citrus fruit extract, ginger extract, pear extract, Japanese apricot concentrate, balloon flower extract, jujube extract, and omija extract) at $0.001-4.0{\mu}g/mL$. Ginger extract, pear extract, Japanese apricot concentrate, balloon flower extract, jujube extract, or omija extract showed no antimicrobial effects on high-concentration of L. monocytogenes (7 Log CFU/mL). However, grapefruit seed extract and citrus fruit extract showed antibacterial effects against L. monocytogenes at 3 and 7 Log CFU/mL with MBCs of 0.001 and $0.002{\mu}g/mL$, respectively. These results indicate that grapefruit seed extract and citrus fruits extract can be used to control L. monocytogenes as natural antimicrobials.

Control of Discoloration of Cedar Wood (Cryptomeria japonica) by Heat and UV Treatment (열처리와 자외선처리를 이용한 삼나무 재색제어)

  • Yoon, Kyung-Jin;Eom, Chang-Deuk;Park, Jun-Ho;Lee, Yang-Woo;Choi, In-Gyu;Lee, Jun-Jae;Yeo, Hwanmyeong
    • Journal of the Korean Wood Science and Technology
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    • v.36 no.6
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    • pp.33-40
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    • 2008
  • Normally, cedar heartwood has a red color. However, it frequently changes black color (blackening phenomenon). It is reported that blackening phenomenon of cedar has been caused by oxidation of phenolics and norlignan extractives under weak alkaline conditions. In this study, heat treatment and UV irradiation were carried out to reduce the difference of color value between blackened wood and bright sap wood. Effects of temperature, moisture content, treatment time and light on decrease of color difference between blackened heartwood and sapwood were evaluated in each treatment. A decrement of different color value between blackened heartwood and bright sapwood by hot-water treatment was bigger than others. An effect of the vacuum drying was similar to that of the kiln drying. UV irradiation decreases the color difference between dried blackened heartwood and bright sapwood. It is suggested that UV irradiation could be used as final treatment to reduce the color difference on wood during drying process. Determination of optimum conditions and development of hybrid process for control of discoloration will be needed in a further study.

Evaluation of Antimicrobial, Antithrombin, and Antioxidant Activity of Dioscorea batatas Decne (마(Dioscorea batatas Decne)의 항균, 항산화 및 항혈전 활성 평가)

  • Kim, Jee-In;Jang, Han-Su;Kim, Jong-Sik;Sohn, Ho-Yong
    • Microbiology and Biotechnology Letters
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    • v.37 no.2
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    • pp.133-139
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    • 2009
  • Yam (Dioscorea batatas Decne) has been recognized as healthy food due to its various biological activities, such as anti-obesity, anti-constipation, anti-proliferation, anti-mutagenic activity, and decrease of blood glucose and cholesterol level. In this study, the methanol extract and its organic solvent fractions were prepared from dried Dioscorea batatas Decne, and their antimicrobial, antithrombin, and antioxidant activity were evaluated, respectively. The 66.7% of methanol extract was fractioned into water residue, and most of total-polyphenol/total-flavonoids were found in ethylacetate fraction. This ethylacetate fraction at $500\;{\mu}g/disc$ concentration showed strong antibacterial activity against gram-negative and gram-positive bacteria, except Staphylococcus aureus. Antifungal activity was not observed in methanol extract and its fractions. But, strong antithrombin activity was found in methanol extract. At 4.8 mg/mL concentration, thrombin time was 99.5 sec, which is coincides with 30% activity of aspirin, a commercial available antithrombosis agent. The ethylacetate fraction showed strong DPPH scavenging activity ($IC_{50}$ of $80.5\;{\mu}g/mL$), compared to vitamin C ($IC_{50}$ of $15.2\;{\mu}g/mL$). Also, the ethylacetate fraction showed strong SOD-like activity and reducing power, which are coincide with 43% of vitamin C and 82.7% of butylated hydroxytoluene activity, respectively.

Analysis of Knit Item Trend Appeared in Foreign Fashion Collections - Analysis for the Proposal of Knit Item Category List and Practical Use - (해외 패션 컬렉션에 나타난 니트 아이템 경향 분석 - 니트 아이템 분류목록의 제안과 실용화를 위한 탐색적 분석 -)

  • Kim, Hye-Young;Lee, Shin-Young
    • The Research Journal of the Costume Culture
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    • v.14 no.5
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    • pp.813-827
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    • 2006
  • In this investigation, the following study was carried out for an experimental proposal of the knit item lists which were not actualized due to lack of studies. First of all, we have put the knit item titles that have been used through the document investigation, into the lists in order to clarify the original item list. Furthermore, we have pointed out the problems and the areas to be developed in the original item lists, and proposed twenty new knit item lists. By defining the design traits of each item, we have established item list which could be classified more systematically. As a result, the knit item titles of twenty newly proposed item titles are knit pull over, knit pull over top, knit top, knit t shirt, knit shirt, knit polo shirt, knit blouse, knit vest, knit hood, knit jumper, knit jacket, knit coat, knit cardigan, knit ensemble, knit cape, knit shawl, knit bikini, knit one-piece, knit pants, and knit skirt. Secondly, in order to investigate the possibility of practical use of twenty knit item lists proposed by this study, we have applied anova with repeated measurement for foreign fashion collection knit item trends of the past 10 years based on the proposed item lists. As a result, four items classified as top, shirt, cardigan, and pants had similar changes in the trend for last 10 years in S/S season while eleven items classified as pull over, pull over top, blouse, vest, jacket, coat, cardigan, ensemble, cape, shawl, and one-piece had similar trend changes for F/W season. The first significance of this study is on the experimental proposal of knit item list which could be used in the actual clothing industry and academic field. Furthermore, by defining the design traits of each knit item, it sublated the confusions brought by vocabularies in design of knit products and distribution in the industry perspective, and it made it possible to categorize the knit items correctly in knit design analysis and knit design education in academic field. The second significance shows that this study brought about positive results in the possibility of industrial academic practical use of proposed list by indicating that most of the knit designs appeared in the foreign collections in the past ten years could be correctly classified through investigational analysis.

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Screening of Inhibitory activities on Angiotensin Converting Enzyme from Medicinal plants (약용식물의 Angiotensin Converting Enzyme 저해활성 탐색)

  • Choi, Geun-Pyo;Chung, Byung-Hee;Lee, Dong-Il;Lee, Hyeon-Yong;Lee, Jin-Ha;Kim, Jong-Dai
    • Korean Journal of Medicinal Crop Science
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    • v.10 no.5
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    • pp.399-402
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    • 2002
  • Angiotensin converting enzyme(ACE) belongs to the class of zinc protease and plays an important role in the regulation of blood pressure. In this experiment, we investigated the inhibitory activities of medicinal plant extracts on ACE. Fifty medicinal plants were selected and the extracts were prepared by refluxing with 70% methanol. Among the extracts, eleven medicinal plant extracts such as Sedum sarmentosum Bunge, Petasites japonicus(s.et z.) Max, Rubus coreanus, Morus bombycis Koidz, Acorus calamus var. angustatus, Glycyrhiza glabra, Equisetum hyemale, Portulaca oleracea L., Prunella vulgaris var. lilacina Nakai, Sorbus commixta Hedl, Allium thunbergii showed more than 50% inhibitory activities, and Paeonia suffruticosa Andr., lnula helenium, Acanthopanax senticosus Harms, Dendrobium moniliforme, Juglans mandshurica, Zizyphus jujuba, Leonurus artemisia, Aster scaber Thunb, Vitex rotundifolia, Platycodon grandiflorum, Prunus persica, Ligularia fischeri showed $40{\sim}49%$ inhibitory activities. Therefore these extracts which contain high ACE inhibitory activities may be useful as antihypertension agents and to the treatment of hypertension.

Exploratory Study on Developing Model for Smoking Cessation Process (금연 과정의 모델 개발을 위한 탐색적 연구)

  • 오현수;김영란
    • Journal of Korean Academy of Nursing
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    • v.27 no.1
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    • pp.71-82
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    • 1997
  • In this paper, the study model, which presents the patterns of how the changing mechanisms are adopted to the changing stages of smoking cessation, was developed by modifying the integrative model of Prochaska et al. (1983) with including seven changing mechanisms which were identified by Oh and Kim(1996). Then the developed study model was exploratively tested with 155 University student between 20 and 29 years of age as subjects. According to the study results. among the five mechanisms. which are significant in explaining the differences between stages. DUNCAN post-comparison showed that the least applied ones were Stimulus Control, Self Determinism, Cognitive Restructuring in the precomplation stage, and Reinforcement and Dramatic Relief. in the relapsed stage. In the comtemplation stage. it was observed that Dramatic Relief is used most frequently and that the other two mechanisms, Information Management and Cognitive Restructuring, showed different results from those inferred in the study hypothesis. In the case of Information Management, it was excluded from the analysis it was not included in explaining significant difference among changing stages, but Cognitive Reconstruction turns out to be a more frequently used mechanism in the action stage rather than in the comtemplation stage. Helping Relationship was also excluded in the post-comparison analysis since it was not included in explaining significant difference among changing stages and Reinforcement was a more frequently used mechanisms in the comtemplation stage. Stimulus Control turns out to be the connecting mechanism which was most frequently used in both the contemplation and action stages. Self Determination was most frequently used in the action stage rather than in both the comtemplation stage and action stage, differing from the presumption of the model. Lastly, subjects in the relapsed stage were utilizing Stimulus Control and Self Determination at the same level as subjects in the precontemplation stage. and the utilization of both Reinformcement and Dramatic Relief was lower than that of the precomtemplation stage, that is, at the lowest level. Only Cognitive Restructuring was used of the same level as the comtemplation stage. The relapsed stage in this study did not represent the preparation for action stage as presumed in the model of Prochaska et. al. (1983) but did show a pattern similar to the initial stage of smoking cessation. However, since this interpretation about the relapser was based on only a small number of relapsers(n=5), this conclusion may not be reliable.

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Effects of the Extracts from Gyrophora esculenta and Coriolus versicolor judae Mycelia on the Growth of Intestinal Bacteria (석이버섯과 운지버섯 균사체 추출물이 장내 세균의 생육에 미치는 영향)

  • Park, Kyoung-Ran;Lee, Woon-Jong;Cho, Min-Gyu;Park, Eui-Seok;Jeong, Jun-Young;Kwon, Oh-Sung;Yoon, Hyang-Sik;Kim, Kwang-Yup
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.6
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    • pp.820-825
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    • 2010
  • The functional food components from various Basidiomycota were investigated to improve human intestinal microflora, especially associated with obesity. EtOH extract from Gyrophora esculenta fruit body and Coriolus versicolor judae mycelia showed antimicrobial activities on Eubacterium limosum, Clostridium perfrigens, Clostridium paraputrificum, Clostridium difficile and Clostridium ramosum, and on Bacteroides fragilis, respectively. Although the 80% EtOH extract from G. esculenta fruit body and hot-water extract from C. versicolor judae mycelia did not reduce weight of the rats in the high fat diet, these extracts showed stability at high temperatures and at wide pH ranges. In the rat group of feeding 80% EtOH extract from G. esculanta fruit body, Bifidobacterium spp. were increased and Clostridium spp. and Eubacterium spp. were decreased compared to the high fat feeding group. Also sensory evaluation was carried out for the development of prototype drink product. These results demonstrated the possibilities of C. versicolor judae and G. esculenta as a functional food components to control intestinal microbial flora.

An Exploratory Study for Identifying Factors Related to Breakfast in Elementary, Middle and High School Students ($\cdot$$\cdot$고 학생의 아침식사와 관련된 요인들에 대한 탐색적 연구)

  • Yi, Bo-Sook;Yang, Il-Sun
    • Korean Journal of Community Nutrition
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    • v.11 no.1
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    • pp.25-38
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    • 2006
  • This study was carried out to identify factors related to breakfasts in elementary, middle and high school students. This study was surveyed by questionnaires and data was analyzed by SPSS program. Exploratory analysis was conducted according to three school student groups (elementary children, middle school students, and high school students). The subjects were 1,886 school students (female 893, male 959) of 51 schools in the nationwide region. The distribution of subjects was elementary school children 544, middle school students 661 and high school students 681. The results are summarized as follows. Only sixty percent of the subjects had breakfast regularly. About one fourth of the subjects had the habit of skipping breakfast or eating it 2$\sim$3 times per week. Frequency of having breakfast and reasions of skipping breakfast were significantly different according to school student groups (p < 0.001 respectively). The rate of skipping breakfast was $14.4\%$ in elementary school, $16.1\%$ in middle school, and $25.0\%$ in high school. The main reason for skipping breakfast was 'not delicious or poor appetite' in elementary school ($42.5\%$), but 'busy' in middle ($50.2\%$) and high school ($61.1\%$). There was no significant difference in frequency of having breakfast according to living areas (rural and urban). There were not significant differences between frequency of having breakfast and BMI and degree of satisfaction on body weight. But there were significant difference in frequency of having breakfast according to economical status (p < 0.05). There were significant differences in degree of school performance according to frequency of having breakfast (p < 0.001) There was significant relationship between the time of attending school and the frequency of having breakfast. But there were significant relationships between frequency of having breakfast and time of rising. These findings suggested that the time of rising was controlled by having enough time that students eat breakfast. And mother (or person who prepares meals) must have more concerns about preparing breakfast for children and students.