• Title/Summary/Keyword: 알코올의존

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The Analysis on Psychological Changes of Unemployed according to the Unemployment Period (실업자의 실업기간별 심리적 변화분석)

  • Park, Hye-Gyeong;Kim, Byeong-Suk;Choi, Jeong-Eun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.7
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    • pp.423-442
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    • 2018
  • This study observes the psychological changes of unemployed people according to their unemployment period. With this what psychological changes they face according to their unemployment period and what psychological characteristics they show, whether if psychological changes and job hunting activities are in relation, and whether if psychological changes affect job hunting activities. The study subjects received unemployment wage and were divided according to before employment, 1~3 months unemployed, and 4 months or more unemployed. An in-depth research of 8 people was conducted within the period of 2017.05~08. The psychological characteristics of people, in the period from when they first sense unemployment possibilities until three months of unemployment, are anger, anxiety, fear, which is a mixed characteristic that does not disappear but continues deepening. In study there was no significant difference in depression, anxiety, anger, social phobia, alcohol, religion factors, low self-esteem, and low self-efficacy in before employment, 1~3 months unemployed, and 4 months or more unemployed. However, the average levels of anger anxiety, depression, and social phobia were higher when the unemployment period was longer and the results of low self-esteem and low self-efficacy support further research.

Motivation for Alcohol Use, Problem Drinking, Family Alcohol Use and Dating Violence among College Students (음주 동기, 문제음주 및 음주 가족력과 대학생의 데이트 폭력)

  • Kyung Hyun Suh
    • Korean Journal of Culture and Social Issue
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    • v.9 no.2
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    • pp.61-78
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    • 2003
  • The researcher examined the relationship between dating violence and drinking behaviors. Study participants included 440 Korean College students(184 males and 256 females) currently involved in heterosexual dating relationships. Participants' ages ranged from 17 to 30(M=20.08, SD=1.89). Questionnaires and psychological tests used included: Straus' Conflict Tactics Scale, Alcohol Use Disorder Identification Test(AUDIT), Cooper's Revised Drinking Motives Questionnaire(DMQ), and Index of Family Alcohol Use. Research designs were 2(gender) × 2(experience of inflicting dating violence), i.e. 2-way MANOVAs. Results suggest students who drink one or more times a week are more likely to commit acts of violence toward their dating partners than students drinking less often. The study revealed males tend to drink with higher social, enhancement, conformity and coping motives than females. The study also showed that students inflicting dating violence drank with higher coping motives than students who did not. Males showed more hazardous, dependent and harmful drinking patterns than females. Also, students who had inflicted dating violence showed a higher degree of these characteristics (hazardous, dependent and harmful drinking patterns) along with a greater family history of alcohol use than participants who had not inflicted dating violence. The findings showed significant 2-way interactions in dependent and harmful drinking patterns. Simple main effect analysis revealed that differences in dependent and harmful drinking patterns in males are more significant than the same differences in females.

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α-Glucosidase, Tyrosinase, and Elastase Inhibitory Effects of Enzymatic Extracts from Ecklonia cava and its Alcohol Metabolizing Activity (감태(E. cava Kjellman) 효소분해산물의 항당뇨 및 알코올 분해능과 미용효과)

  • Kim, Hye-Youn;Cho, Eun-Kyung;Kang, Su-Hee;Bae, Jeong-Mi;Choi, Young-Ju
    • Journal of Life Science
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    • v.22 no.6
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    • pp.751-759
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    • 2012
  • Microbulbifer sp. was used to acquire the degrading products from Ecklonia cava (DPEC) and the products were investigated to determine the physiological activities. Firstly, 2,2-diphenyl-1-picrylhydrazyl (DPPH) activity and superoxide dismutase (SOD) assay were about 84.1% and 89.6% at 2.5 mg/ml, respectively. In addition, nitrite scavenging ability was shown to be 56.3% at 0.5 mg/ml on pH 1.2. ${\alpha}$-Glucosidase inhibitory activity was increased in a dose-dependent manner and was about 58.7% at 2.5 mg/ml. To determine the influence of DPEC on alcohol metabolism, the generating activity of reduced-nicotinamide adenine dinucleotide (NADH) by alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) were measured. Facilitating rates of ADH and ALDH activities by DPEC were 123.3% and 215.2% at 2.5 mg/ml, respectively. For analyses of anti-wrinkling and whitening effects, its elastase and tyrosinase inhibitory activities were measured and were about 73.1% and 42.2% at 2.5 mg/ml, respectively. These results indicated that DPEC has valuable biological attributes owing to its antioxidant, nitrite scavenging, and alcohol metabolizing activities and ${\alpha}$-glucosidase, elastase, and tyrosinase inhibitory activities.

Anxiety, Impulsiveness, and Drinking Problems in Employed Women (직장 여성의 불안, 충동성과 음주문제)

  • Lee, Hyun Jae;Han, Doug Hyun;Lee, Young Sik;Kee, Baik Seok;Kwon, Hye Jin;Park, Doo Byung
    • Anxiety and mood
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    • v.7 no.2
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    • pp.73-78
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    • 2011
  • Objectives : This study examined drinking habits, anxiety, and impulsiveness in employed women. Methods : We sampled 925 residents aged over 20 years in Gwanak-gu of Seoul. In the process, we divided subjects into employed women and unemployed women groups and then used the Korean Version of Alcohol Use Disorder Identification Test (AUDIT-K), State-Trait Anxiety Inventory (STAI), and Barratt Impulsiveness Scale (BIS) to identify patterns in subjects' alcohol drinking, anxiety and impulsiveness. Results : Among the 925 respondents, 95.7% drank alcohol, and after the analysis, female problematic drinking ($12{\leq}AUDIT-K{\leq}25$) and alcohol dependence ($AUDIT-K{\geq}26$) was apparent in 61 (9.5%) and 2 respondents (0.3%), respectively. Female respondents who had jobs tended to drink more and exhibit higher ratios of problematic drinking, with a higher exposure to alcohol than those that were unemployed. The psychological attributes related to female respondents' alcohol problems related to state of anxiety and impulsiveness. Employed women respondents also showed a higher state of anxiety and impulsiveness than unemployed women. Conclusion : Controlling the frequency of exposure to alcohol, anxiety, and impulsiveness in employed women should be considered to be crucial controlling factors related to the hazards of excessive drinking.

Preparation of $SiO_2-TiO_2$ Porous Composite Pigments Using a Pickering Emulsion Method as Template (피커링 에멀젼을 형판으로 하는 $SiO_2-TiO_2$ 다공성 분체의 제조)

  • Lee, Sang-Gil;Kim, Young-Ho;Hong, Jun-Ki;Pyo, Hyeong-Bae;Lee, Dong-Kyu
    • Journal of the Korean Applied Science and Technology
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    • v.29 no.3
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    • pp.377-392
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    • 2012
  • It has been known that small solid particles act as a stabilizer in pickering emulsion system. In this study, we successfully prepared stable pickering emulsion in n-hexylalcohol and water system with $TiO_2$ whose surface was treated by alkylsilane. The optimum condition to prepare pickering emulsion stabilized by $TiO_2$ particles was determined by amount of $TiO_2$ particles and ratio of water and oil phase. The type of pickering emulsion was dependent on wettability of particles for water and n-hexylalcohol. When the amount of $TiO_2$ particles increased up to 5.00 wt%, the stability of pickering emulsion was showed to be improved. The most stable pickering emulsion was prepared in the case of W/O type which has the ratio of oil and water phase (3 : 7). We tried to prepare porous $SiO_2-TiO_2$ composite pigments using a pickering emulsion as template at the optimal condition. Porous pigments were synthesized with Ludox HS-30 as an inorganic material by sol-gel process. The characteristics and shape of porous pigments were measured by optical microscope, SEM, BET, XRD and EDS.

Anti-Diabetic, Alcohol Metabolizing Enzyme, and Hepatoprotective Activity of Acer tegmentosum Maxim. Stem Extracts (산겨릅나무 줄기 추출물의 항당뇨, 알코올 대사 효소 및 간 보호 활성)

  • Cho, Eun Kyung;Jung, Kyung Im;Choi, Young Ju
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.12
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    • pp.1785-1792
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    • 2015
  • This study was carried out to investigate the antidiabetic, alcohol metabolism, anti-inflammatory, and hepatoprotective effects of Acer tegmentosum extracts (ATE). A. tegmentosum has been traditionally used as a folk medicine to treat hepatic disorders. The antioxidative activities of ATE were measured by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and superoxide (SOD) assay. DPPH radical scavenging and SOD activities of ATE were about 89% and 82.9% at $0.5{\mu}g/mL$, respectively. Alcohol dehydrogenase and acetaldehyde dehydrogenase activities were 118.0% and 177% at 2 mg/mL, respectively. ${\alpha}-Glucosidase$ inhibitory activity of ATE was 75% higher at $50{\mu}g/mL$ and remarkably increased in a dose-dependent manner. Nitric oxide productions in macrophage RAW 264.7 cells stimulated by lipopolysaccharide was reduced to 16.7% by addition of ATE at 1 mg/mL. ATE showed significant protective effects against tacrine-induced cytotoxicity in Hep G2 cells at $100{\mu}g/mL$. Based on our results, we conclude that ATE may be used as a major pharmacological agent and anti-diabetic, anti-hepatitis, and anti-inflammatory remedy.

Study on the Selection of Solvent for Purificatino of p-Dioxanone by Crystallization Method (결정화에 의한 파라디옥산온의 정제를 위한 용매선정에 관한 연구)

  • kim, Sung-Il;Koh, Joo-young;Kim, Chul-Ung;Koh, Jae-Cheon;Park, So-Jin;Seo, Young-Jong;Choi, Byung-Ryul
    • Applied Chemistry for Engineering
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    • v.16 no.4
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    • pp.581-587
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    • 2005
  • In order to obtain a highly purified p-dioxanone (PDX) as monomer of biodegradable polymer, suitable solvent must be selected. The selection was based on the solubility of impurities, and partial layer melt crystallization were carried out under the presence of solvent. The solubility of PDX in various solvents such as ethyl acetate, tetrahydrofuran, acetone, alcohols (methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol) were measured over the temperature range of $-10{\sim}15^{\circ}C$. As solubility parameters, the mixing and dissolution enthalpy between the PDX and the solvents was studied based on empirical equations and the regular solution theory. The solubility and the temperature dependency of the solubility with the solvents of acetone, ethylacetate, and tetrahydrofuran of PDX were shown to have relatively high values compared to the alcohol type solvents. Also, in same alcohols, the smaller molecules and higher polarity gave higher solvency. In partial layer melt crystallization, small amount of ethylacetate selectively dissolved impurities and gave highly purified p-dioxanone, over 99.9% purity.

The Hepatoprotective Effects of Hep G2 Cells and the Alcohol-Metabolizing Enzyme Activities of Lemon-Myrtle (Backhousia citriodora) Leaf Extracts (레몬 머틀 잎 추출물의 Hep G2 세포에서의 간 보호 효과 및 알코올대사 효소활성)

  • Jung, Kyung Im;Kim, Pan Kil;Gal, Sang Wan;Choi, Young Ju
    • Journal of Life Science
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    • v.27 no.11
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    • pp.1262-1268
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    • 2017
  • Lemon myrtle (Backhousia citriodora), a plant in the Myrtaceae family, is native to the semitropical rain-forests of Queensland and is presumably the most commercialized native spice. In Australian thousands of lemon-myrtle trees are under tillage. This study was carried out to investigate the alcohol metabolism, hepatoprotective effects and antidiabetic, tyrosinase inhibitory activity of hot-water (LMW) and 80% ethanol (LME) extracts from lemon-myrtle leaves. The alpha-glucosidase (${\alpha}$-glucosidase) inhibitory activities of the LMW and LME extracts were 7.66% and 40.29% at 1 mg/ml (p<0.05), respectively. The tyrosinase inhibitory activity of the LME extract was about 38.26 % at 1 mg/ml. The effects the LMW and LME extracts had on alcohol-metabolizing activities were determined by measuring the generation of reduced nicotinamide-adenine dinucleotide (NADH) by acetaldehyde dehydrogenase (ALDH) and alcohol dehydrogenase (ADH). The ADH activities of the LMW and LME extracts significantly increased in a dose-dependent manner and were about 154.40% and 192.03% at 1 mg/ml, respectively (p<0.05). The ALDH activities of the LMW and LME extracts also significantly increased in a dose-dependent manner and were about 151.14% and 192.34% at 1 mg/ml, respectively (p<0.05). At $100{\mu}g/ml$, the LMW and LME extracts showed significant protective effects against tacrine-induced cytotoxicity in Hep G2 cells. The results suggested that Backhousia citriodora leaf extracts have the potential to be significant sources for natural health products.

A Study of a Relapse Prevention Program for Alcoholics focused on Action Methods (행위기법을 중심으로 한 알코올의존 재발방지 프로그램 개발에 관한 연구)

  • No, In-Suk;Kim, Seong-Jae
    • Journal of East-West Nursing Research
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    • v.10 no.1
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    • pp.27-40
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    • 2004
  • Relapse is one of the most series problems in alcoholics treatment. Previous studies have shown that significant proportions of treated alcoholics show an early relapse and go through a chronic phase. It is necessity to find more effective relapse prevention program. The Purpose of this study was to develop a relapse prevention program that emphasis on group activities using various action methods. Previous studies revealed that there was no effective therapeutic strategy to prevent relapse and proposed that action methods were more practical ways to be able ti cope with high-risk situation than verbal methods such as discussions and lectures. The special attempt of this program was the application of various actions methods and the integration of many psychosocial therapeutic strategies as compared with many relapse prevention programs. The theoretical framework of this relapse prevention program was based on mainly the Marlatt's Relapse Prevention model and Prochescha and DiClemente's Transtheoretical model. This Program consists of eight structure sessions. Every session has three phase: Warm-up phase, action phase, and sharing phase as sociodrama structure. Sociodrama is based on many of the principles of adult learning. And sociodrama looks at how groups work through an understanding of systems and role theory. Therefore, in working with a group a therapist might explore with them the roles that people play, roles that are missing at present such a visionary and how people can develop new roles or new ways of playing existing roles. The researchers explained the purpose of this study to all participants after their agreement to participate. Voluntary informed consent was obtained from all participants. Every session allows participants to recognize personal specific high-risk situation and to examine possible coping behaviors creatively. Multiple solutions can be proposed, tested and evaluated dramatically, giving new insights or breakthroughs in thinking. This is vital for the initiation of change, and if appropriate, expanding new role development. The first two sessions aim at understanding of relapse process and recognize of high-risk situations focused on orientation about action methods. The next four sessions deal with high-risk situations. The last two sessions give participants opportunities to venture new life-styles. The methods and approaches used in this program utilized as a tool to explore and practice possible coping strategies. and this program can contribute to prevent relapse episode if tune with the particular high-risk situation by using active practices in safe environment.

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Protective effects of Carthamus tinctorius L. seed on C6 glial cells treated with ethanol (홍화씨 추출물의 in vitro 항산화 및 ethanol로 손상을 유도한 C6 신경교세포 보호 효과)

  • Choi, Seung Hak;Park, Chan Hum;Cho, Eun Ju;Kim, Ji Hyun;Seo, Weon Taek
    • Journal of Applied Biological Chemistry
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    • v.64 no.1
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    • pp.69-74
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    • 2021
  • Chronic alcohol is responsible for oxidative stress and neurodegenerative diseases such as dementia. In the present study, we investigated the antioxidant activity and protective effects of seed of Carthamus tinctorius L. on ethanol-induced C6 glial cells. Antioxidant effect of seed of C. tinctorius L. was measured by scavenging activity of 1,1-diphenyl-2-prcrylhydrazy (DPPH), hydroxyl radical (·OH), superoxide radical, and nitric oxide. The seed of C. tinctorius L. extract showed significant radical scavenging activities in a concentration-dependent manner. In particular, it revealed strong DPPH and ·OH scavenging activity, displaying more than 80% at 500 and 100 ㎍/mL, respectively. Treatment of 500 mM ethanol to C6 glial cell led to decline of cell viability and elevation of reactive oxygen species (ROS) generation. However, seed of C. tinctorius L.-treated groups significantly increased cell viability and decreased ROS levels, compared to ethanol-induced control group. These results suggest that seed of C. tinctorius L. would have protective effect against neuronal oxidative stress induced by alcohol.