• The Korean Journal of Physiology and Pharmacology
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• 제6권2호
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• pp.87-91
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• 2002

The aim of this study was to investigate the role of $Ca^{2+}-channel$ blockers in norepinephrine (NE) release from rat hippocampus. Slices and synaptosomes were incubated with $[^3H]-NE$ and the releases of the labelled products were evoked by 25 mM KCl stimulation. Nifedipine, diltiazem, nicardipine, flunarizine and pimozide did not affect the evoked and basal release of NE in the slice. But, diltiazem, nicardipine and flunarizine decreased the evoked NE release with a dose-related manner without any change of the basal release from synaptosomes. Also, a large dose of pimozide produced modest decrement of NE release. ${\omega}-conotoxin$ (CTx) GVIA decreased the evoked NE release in a dose-dependent manner without changing the basal release. And ${\omega}-CTxMVIIC$ decreased the evoked NE release in the synaoptosomes without any effect in the slice, but the effect of decrement was far less than that of ${\omega}-CTxGVIA.$ In interaction experiments with ${\omega}-CTxGVIA,\;{\omega}-CTxMVIIC$ slightly potentiated the effect of ${\omega}-CTxGVIA$ on NE release in the slice and synaptosomal preparations. These results suggest that the NE release in the rat hippocampus is mediated mainly by N-type $Ca^{2+}-channels,$ and that other types such as L-, T- and/or P/Q-type $Ca^{2+}-channels$ could also be participate in this process.

• The Korean Journal of Physiology and Pharmacology
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• 제11권1호
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• pp.21-30
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• 2007

The present study was designed to establish comparatively the inhibitory effects of cilnidipine(CNP), nifedipine(NIF), and $\omega$-conotoxin GVIA(CTX) on the release of CA evoked by cholinergic stimulation and membrane depolarization from the isolated perfused model of the rat adrenal medulla. CNP(3 ${\mu}M$), NIF(3 ${\mu}M$), and CTX(3 ${\mu}M$) perfused into an adrenal vein for 60 min produced greatly inhibition in CA secretory responses evoked by ACh($5.32{\times}10^{-3}M$), DMPP($10^{-4}M$ for 2 min), McN-A-343($10^{-4}M$ for 2 min), high $K^+(5.6{\times}10^{-2}M)$, Bay-K-8644($10^{-5}M$), and cyclopiazonic acid($10^{-5}M$), respectively. For the CA release evoked by ACh and Bay-K-8644, the following rank order of potency was obtained: CNP>NIF>CTX. The rank order for the CA release evoked by McN-A-343 and cyclopiazonic acid was CNP>NIF>CTX. Also, the rank orders for high $K^+$ and for DMPP were NIF>CTX>CNP and NIF>CNP>CTX, respectively. Taken together, these results demonstrate that all voltage-dependent $Ca^{2+}$ channels(VDCCs) blockers of cilnidipine, nifedipine, and $\omega$-conotoxin GVIA inhibit greatly the CA release evoked by stimulation of cholinergic(both nicotinic and muscarinic) receptors and the membrane depolarization without affecting the basal release from the isolated perfused rat adrenal gland. It seems likely that the inhibitory effects of cilnidipine, nifedipine, and $\omega$-conotoxin GVIA are mediated by the blockade of both L- and N-type, L-type only, and N-type only VDCCs located on the rat adrenomedullary chromaffin cells, respectively, which are relevant to $Ca^{2+}$ mobilization. It is also suggested that N-type VDCCs play an important role in the rat adrenomedullary CA secretion, in addition to L-type VDCCs.

• 대한수학회보
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• 제37권1호
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• pp.127-134
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• 2000

Let $\Omega$ be a bounded pseudoconvex domain in$C^{n}$ with smooth defining function r and let$z_0\; {\in}\; b{\Omega}$ be a point of finite type. We also assume that $\Omega$ is convex in a neighborhood of $z_0$. Then we prove that all the holomorphic sectional curvatures of the Bergman metric of $\Omega$ are bounded below by a negative constant near $z_0$.

• Korean Journal of Mathematics
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• 제32권1호
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• pp.15-25
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• 2024

In this paper, we obtain common fixed point theorems for three mappings of contractive type in the setting of generalized modular metric spaces. Our results generalize many results available in the literature including common fixed point theorems.

• 한국산학기술학회논문지
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• 제12권2호
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• pp.835-840
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• 2011

본 연구에서는 직경이 50mm, 두께가 4.5mm인 디스크형 압전 변압기의 구동부와 발전부의 전극에 대한 대칭성을 고려하여 2, 4 및 8등분으로 각각 분할하였다. 이렇게 분할된 압전 변압기에 부하저항을 변화($100{\Omega}{\sim}10_{K\Omega}$)시키면서 전기적 특성을 측정하고, 이를 토대로 한 압전변압기의 승압비 및 효율에 관한 메카니즘을 정량적으로 해석하였다.

• 대한수학회보
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• 제54권3호
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• pp.993-1002
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• 2017

Let ${\Omega}$ be a bounded, uniformly totally pseudoconvex domain in ${\mathbb{C}}^2$ with the smooth boundary b${\Omega}$. Assuming that ${\Omega}$ satisfies the negative ${\bar{\partial}}$ property. Let M be a positive, finite area divisor of ${\Omega}$. In this paper, we will prove that: if ${\Omega}$ admits a maximal type F and the ${\check{C}}eck$ cohomology class of the second order vanishes in ${\Omega}$, there is a bounded holomorphic function in ${\Omega}$ such that its zero set is M. The proof is based on the method given by Shaw [27].

• 대한수학회보
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• 제53권6호
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• pp.1805-1821
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• 2016

In this paper, we are concerned with the nonlinear elliptic equations of the p(x)-Laplace type $$\{\begin{array}{lll}-div(a(x,{\nabla}u))+{\mid}u{\mid}^{p(x)-2}u={\lambda}f(x,u) && in\;{\Omega}\\(a(x,{\nabla}u)\frac{{\partial}u}{{\partial}n}={\lambda}{\theta}g(x,u) && on\;{\partial}{\Omega},\end{array}$$ which is subject to nonlinear Neumann boundary condition. Here the function a(x, v) is of type${\mid}v{\mid}^{p(x)-2}v$ with continuous function $p:{\bar{\Omega}}{\rightarrow}(1,{\infty})$ and the functions f, g satisfy a $Carath{\acute{e}}odory$ condition. The main purpose of this paper is to establish the existence of at least three solutions for the above problem by applying three critical points theory due to Ricceri. Furthermore, we localize three critical points interval for the given problem as applications of the theorem introduced by Arcoya and Carmona.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 1997년도 춘계학술대회논문집
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• pp.165-170
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• 1997

The study presents an computer-aided analysis and its design for the forming process of $\Omega$-type bellows tube. Finite element analysis was carried out to perform the process simulation. Based on the analytic results of various conditions, the forming conditions used for angled U-type bellows tube were settled. The 3D modeling was constructed by I-DEAS and PAM-STAMP was used for process simulation. It is concluded that the spring back of formed bellows influences $\Omega$-shape and these results can be used for the process design.

• 한국정밀공학회지
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• 제14권10호
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• pp.85-90
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• 1997

The study presents a computer-aided analysis and its design for the forming process of .OMEGA. -type bellows tubes. Finite element analysis was carried out to perform the process simulation. Bsed on the analytic results of various conditions, the forming conditions used for angled U-type bellows tubes were determined. The 3-D modeling was constructed by I-DEAS and the process simulation was constructed by PAM- STAMP. It is concluded that the difference of height between die and bellows during the forming process causes a non-uniform shape of the bellows and also influences .OMEGA. -shape. These results can be utilized for the process design.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2001년도 추계학술대회 논문집 Vol.14 No.1
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• pp.197-200
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• 2001

In this letter, we report on the investigation of Ni/Si/Ni Ohmic contacts to n-type 4H-SiC. Ohmic contacts have been formed by a vacuum annealing and $N_2$ gas ambient annealing method at $950^{\circ}C$ for 10 min. The specific contact resistivity ( $\rho_{c}$ ), sheet resistance($R_s$), contact resistance($R_c$), transfer length($L_T$) were calculated from resistance($R_T$) versus contact spacing(d) measurements obtained from 10 TLM(transmission line method) structures. The resulting average values of vacuum annealing sample were $\rho_{c}=3.8{\times}10^{-5}\Omega cm^{3}$, $R_{c}=4.9{\Omega}$, $R_{T}=9.8{\Omega}$ and $L_{T}=15.5{\mu}m$, resulting average values of another sample were $\rho_{c}=2.29{\times}10^{-4}\Omega cm^{3}$, $R_{c}=12.9{\Omega}$ and $R_{T}=25.8{\Omega}$. The physical properties of contacts were examined using X-Ray Diffraction and Auger analysis, there was a uniform intermixing of the Si and Ni, migration of Ni into the SiC.