The purpose of this study is to analyze the relationship between logistics safety climate, logistics safety behavior, and logistics safety performance and the mediating effects of safety knowledge and safety motivation, and to suggest its strategic implications for the improvement of the logistics safety performance. Based on previous researches related to logistics safety, safety climate, safety knowledge, safety motivation, safety behavior and safety performance, research models and hypotheses were set up and questionnaires were conducted. For the hypothesis test, reliability analysis and validity analysis, confirmatory factor analysis, structural equation model analysis, and bootstrapping were applied. As a result of the empirical analysis, the logistics safety climate had a significant positive effect on logistics safety knowledge, logistics safety motivation, and logistics safety behavior, whereas logistics safety knowledge and logistics safety motivation had a meaningful positive effect on logistics safety behavior. Further, logistics safety behavior was found to have a significant positive effect on logistics safety performance. Safety behavior had a significant mediating effect, but safety knowledge and safety motivation did not. However, logistics safety climate, logistics safety knowledge, and logistics safety motivation did not have a significant effect on logistics safety performance.