Objective : The Orthodox Transmission of Medicine(醫學或問) in Yi Xue Zheng Chuan(醫學正傳) are inventive and important in medical opinions of Yu Tuan. Methods : The 51 provisons of Orthodox Transmission of Medicine(醫學或問) are researched with overall and some important theories about San jiao (三焦) and Ming men(命門) are examined in detail that Yu Tuan insist. Result & Conclusion : Yu Tuan insist that San jiao-celom theory(腔子三焦說), Both kidney-Ming men theory (兩腎皆爲命門說) and inventive Harmful hyperactivityand respondinginhibition theory (亢害承制論) in The Orthodox Transmission of Medicine(醫學或問).

Objectives : Clinical data in traditional medicine, such as Korean medicine, traditional Chinese medicine have a long history of accumulating evidence and these rich data are recorded in classic literature. We have conducted a study of developing an algorithm that support clinical diagnosis with composing both users knowledge and data obtained from literature. In order to define necessary information and required steps in diagnosis procedure, we have established a clinical diagnostic procedure including a step of collecting patients symptoms, a step of determining candidates, a step of diagnostic decisions, a step of deciding of treatment and a step of adjusting medicinal treatment. Methods : Our study have been based on the following premises. 1. Using data obtained from literature contributes to accurate diagnosis 2. Displaying the data before users request contributes to accurate conclusion. Displaying before users request enable users to recognize their overlooking a fact on purpose or not. 3. Checking symptoms that are commonly accompanied with a group of diseases that accompany symptoms appealed by a patient contributes to accurate conclusion. These symptoms are worthy of checking. 4. Comparing more than two candidates contributes to accurate conclusion. Users can compare their accompanied symptoms with patients symptoms and this helps users to make a decision. Results : Based on the above premises, we have developed an literature based algorithm to provide various functions, such as recommending symptoms to check, comparing groups of symptoms, differential diagnosis, recommending medicinal materials to prescribe, and more. Conclusions : By the results of simulation with virtual diagnostic scenario, we concluded this algorithm is useful helping clinician in diagnosis procedure.

Objectives : This report describes the original references of 154 formulas related to the use of Rhei Rhizoma main blended from Dongeuibogam. Methods : This study analyzes the original references of 154 formulas including Rhei Rhizoma as a key component in Dongeuibogam. Results : There were five types as follows: 1.There is no exact match between 154 formulas in Dongeuibogam and the original formulas in references. 2. Case that could not found the original formula in reference: 22%. 3. Case that the citation is the similar to the original reference: 4%. 4. Case that the citation is not same to expression but contents basically: 73%. 5. Case of addition of content: 1% Conclusions : Most formulas related to the use of Rhei Rhizoma main blended from Dongeuibogam are similar to the contents in the original references. But we can find that Heo Jun, who writes Dongeuibogam, modifies the contents for his intention of editing, idea and situation in Korea.

This study is based on "Hoesamgyeong(會三經)", the interpretation of the Lecture on Truth of "Samilshingo(三一神誥:Korea's national scripture)". And the goal of this study is to arrange theoretical system of Korean traditional qigong training by doing research on the principles of qigong that are contained in Yookdaesungsang(六大成象) on the basis of Traditional Korean Medicine. Yookdaesungsang(六大成象) is the ideas that appeared for the first time in "Hoesamgyeong(會三經)". Yookdaesungsang(六大成象) refers to Kong(空), Yol(熱), Jin(震), Seup(濕), Han(寒) and Ko(固), which mean six elements of nature. And they correspond with Sung(性), Myoung(命), Jung(精), Sim(心), Ki(氣) and Shin(身) respectively, which are fundamental components of human beings according to the Lecture on Truth of "Samilshingo(三一神誥)". This has a thread of connection with the ideas of 'the unity of nature and human beings(天人合一)' or 'the correspondence between nature and human beings(天人相應)' in Traditional Korean Medicine. From the standpoint of modern science, what are more tangible such as Seup(濕), Han(寒), and Ko(固) are considered as changes in states of matter by activities, while what are relatively intangible such as Kong(空), Yol(熱), and Jin(震) are regarded as wave energy. And in the ideas of three yin(三陰) and three yang(三陽), on which the meridian system of Traditional Korean Medicine is based, Taeyang(太陽)-Soeum(少陰), Yangmyung(陽明)-Taeeum(太陰), and Soyang(少陽)-Gweoleum(厥陰) are respectively ins and outs of the human body and they keep the balance between yin and yang such as cold(寒)-hot(熱), dry(燥)-wet(濕), and slow(緩)-fast(急). As these cold(寒)-hot(熱), dry(燥)-wet(濕), and slow(緩)-fast(急) correspond with Han(寒)-Yol(熱), Jin(震)-Seup(濕), and Kong(空)-Ko(固), the correlation between Yookdaesungsang(六大成象) and the meridian system can be ascertained. As mentioned above, the principles of Qigong in "Hoesamgyeong(會三經)" are based on traditional ideas and accord closely with the principles of Traditional Korean Medicine. Therefore, further researches on the correlations between principles of Qigong unique to Korean tradition and Traditional Korean Medicine are required.

Objective : The aim of this study is identify major trend and characteristics of studies on aromatherapy in Korea. Methods : We searched the three electronic database(RISS, NDSL, KTKP) and manually checked related Korean journals and reference lists 2000 up to June 2014. The studies were analyzed based on publication year, type of paper, intervention method, type of disease, type of aroma. Results : We included 79 articles in this study. 1. 5 papers were published annually on average. 2. After classifying papers by the speciality of thesis and journal, continuous study was followed not only nursing, but also in many specialities like alternative medicine, korean medicine. 3. Aroma therapy is effect of stress, anxiety, insomnia. 4. Many used interventions are inhalation. 5. The most commonly used in aromatherapy is lavender. Conclusions : These results suggest that Aromatherapy research is insufficient in korean medicine. But more research is needed to relieve stress, anxiety in the future.

Objectives : This study aimed to investigate the medical contents of Korean medical textbooks and intervention usage in clinical practice. Method : We conducted an email survey of Doctors of Korean Medicine(DKMs) registered with the Association of Korean Medicine and analyzed the 259 responses that we received. Results : 1, The study showed that most DKMs used western medical knowledge concerning "history taking and diagnosis"(96.5%), "management and prevention"(95.8%), "causes and overview"(91.9%), and "prognosis"(90.3%). DKMs did not usually use western medical knowledge with regard to "diagnosis and treatment evaluation tools"(40.9%) or "western medical treatments"(25.1%) in their clinical practice. 2. Of the DKMs surveyed, 39.0% usually used traditional and western medical terms at similar levels of frequency in explaining their patients' conditions, while 35.9% used western medical terms more often and 20.8% used Korean traditional medical terms more often. 3. Most DKMs usually used acupuncture, herbal medicine, cupping therapy, Moxibustion in their practice and used herbal prescriptions presented in Dongeuibogam(57.1%), Bangyakhappyeon(52.9%), and Sa-Sang Constitutional Medicine(36.7%), although 27.8% used their own herbal prescriptions in creating for patients. In practice, DKMs usually used meridian acupuncture(64.1%), needling myofascial trigger points(54.8%), sa-am acupuncture(42.1%), dong-shi acupuncture therapy(24.7%), and constitutional acupuncture therapy(8.5%). Conclusions : We found that most DKMs use western medical contents as well as Korean medical contents in clinical practice. New Korean medical contents should be establish based on these results.

Glycyrrhizae Radix et Rhizoma has been extensively used by human beings as a medicinal herb as well as natural sweetener. In this study, we performed quantification analysis of three major constituents including liquiritin, glycyrrhizin, and glycyrrhetinic acid in the 70% ethanol extracts of non-processed Glycyrrhizae Radix et Rhizoma and processed Glycyrrhizae Radix et Rhizoma using a high-performance liquid chromatography coupled with photodiode array detector. The analytical column for separation of the 3 constituents used a Gemini C18 column kept at $40^{\circ}C$ by the gradient elution of two mobile phase. The amounts of liquiritin, glycyrrhizin, and glycyrrhetinic acid in non-processed Glycyrrhizae Radix et Rhizoma were 2.57%, 3.52%, and not detected. After processing by roasting, the best roasting temperature and time of iquiritin, glycyrrhizin, and glycyrrhetinic acid were $160^{\circ}C$-15 min (2.46%), $160^{\circ}C$-15 min (3.67%), and $240^{\circ}C$-15 min (0.76%), respectively.

Objectives : In this study, the antioxidant activities of the 80% ethanol and hot water extracts of Euphorbia supina Rafinesque were investigated. Methods : We measured total phenol contents, flavonoid contents, 2,2-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay, 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging assay. The production of reactive oxygen species was measured in LPS-induced RAW 264.7 cells using flow cytometry system. Results : The content of phenol in the hot water extract was $65.529{\pm}0.462mg/g$ and $126.932{\pm}1.894mg/g$ in the 80% ethanol extract, and that of flavonoid in the hot water extract was $16.063{\pm}0.471mg/g$ and $29.159{\pm}1.963mg/g$ in the ethanol extract. The 80% ethanol extract also showed higher DPPH and ABTS radical scavenging activities ($90.8{\pm}1.0%$ and $92.5{\pm}0.7%$) than the hot water extract ($81.5{\pm}0.5%$ and $91.5{\pm}0.2%$). The production of reactive oxygen species(ROS) was reduced dose-dependently by 80% ethanol and hot water extract at concentration of 1, 10 and $100{\mu}g/m{\ell}$ of RAW 264.7 cells. Conclusion : According to these results, the 80% ethanol extract of Euphorbia supina Rafinesque has a good anti-oxidative effects than the hot water extract. Thus, the 80% ethanol extract of Euphorbia supina Rafinesque may serve as useful natural antioxidants.

Objectives : There are plenty of medical record of acupuncture & moxibustion in Traditional East Asian medicine(TEAM). We performed this study to find out the hidden criteria lies on this record to choose proper acupoints. Methods : "Zhenjiuzishengjing", ancient TEAM book was analysed using document clustering techniques. Corpus was made from this book. It contained 196 texts driven from each symptoms. Each texts converted to vector representing frequency of 349 acupoints. Distance of vectors calculated by weighted Euclidean distance method. According to this distances, hierarchical clustering of symptoms was builded. Results : The cluster consisted of five large groups. they had high corelation with body part; head and face, chest, abdomen, upper extremity, lower extremity, back. Conclusions : It assumes that body part of symptom is the most importance criteria of acupoints selecting. some high similar symptom vectors consolidated this result. the other criteria is cause and pathway of illness. some symptoms bound together which had common cause and pathway.

Objectives : The purpose of this study is to detect the change of pattern according to phase and to identify the associated factors with depression in stroke patients. Methods : The study was designed as a longitudinal study. Data was collected from 90 subjects, who were diagnosed with stroke using a brain MRI. The instruments included rehabilitation will, social support, FIM(Functional Independence Measure), NIHSS(National Institute of Health Stroke Scale), and BDI(Beck Depression Index). The collected data were analyzed using by SPSS 19.0 program package. Results : There were significant differences of depression pattern among the three phases. The most depression associated factor was the level of FIM. Conclusion : These results will support strategies for intervention to improve depression of stroke patients. Most affecting factors should be considered for depression intervention.

Objective : This is clinical about the Wei syndrome(痿證)-patient diagnosed as Guillian-Barre Syndrome(GBS). GBS, What is called acute inflammatory plolyneuritis, is a disorder in which the body's immune system attacks parts of peripheral nerve system. It is characterized by the rapid onset of weakness, paralysis of the legs, arms, breathing muscles and face. But the analysis of CSF and electical tests on nerve and muscle function can be performed to confirm the diagnosis. Most cases occur shortly after a viral infection. Methods & Result : This is the clinical report about the one patient diagnosed as Guillain-Barre Syndrome. The patient, 46-year-old men had weakness in both legs and arms after divertculitis. His weakness and general condition improved after oriental medical treatment and acupuncture. As a result, symptoms were improved remarkably. Conclusion : We report that we had good effects of oriental medical treatment on Guillain-Barre Syndrome.

A 30 year old female patient suffering from metabolic syndrome, who was diagnosed with hyperglycemia, dyslipidemia and diabetes 2 years ago, was treated with Traditional Korean Medicine including acupuncture, herbal medicine and tuina for one month. After the treatments, her fasting blood sugar level was remarkably decreased (from $304mg/d{\ell}$ to $74mg/d{\ell}$). And the levels of blood lipids were decreased as well ; the level of TG was decreased from $330mg/d{\ell}$ to $90mg/d{\ell}$, the level of total cholesterol was decreased from $217mg/d{\ell}$ to $111mg/d{\ell}$, the level of LDL was decreased from $119mg/d{\ell}$ to $53mg/d{\ell}$). The waist circumference was also decreased from 96 cm to 90.5 cm. Korean Medical therapies may bring a new clue for the treatment of metabolic syndrome with diabetes.

상완골 간부 골절에 동반된 요골신경 손상을 가진 1명의 환자를 대상으로 "내경(內經)"의 독취양명치법(獨取陽明治法)에 따라 침구치료, 약침치료, 물리치료와 한약치료를 병행하였다. 손목관절의 하수 및 근력약화에 대한 치료성적으로 평가하기 위해 완관절의 운동범위와 능동저항검사를 통한 상대적인 지수를 평가하였으며, 요골신경마비로 인한 장악력의 약화정도는 악력측정기를 사용하여 평가하였다. 수지의 비증의 정도는 Numeric Rating Sclae(NRS) 사정법에 따라 평가하였다. 환자는 발병일로부터 약 6주째에 첫 회복징후를 보이기 시작하였으며, 발병이로부터 약 11.5주째에 가벼운 물건에 대한 집게운동이 가능하며 일상생활을 하는데에 큰 지장이 없는 수준으로 회복되었다. 이는 상완골 간부 골절이 동반된 요골신경손상의 자연회복시기보다 빠른 것으로, "내경(內經)"의 독취양명치법(獨取陽明治法)에 따른 한방치료요법이 상완골 골절에 동반된 요골신경손상의 치료에 효과가 있음을 알 수 있었다.

Purpose : The purpose of this report is to record the effects of oriental treatments for the abnormal uterine bleeding Methods : This is a case report of a 16 year old female patient suffering from abnormal uterine bleeding for eight months. She was treated by Herb therapy for 3 months. During the treatments, we checked changes of symptoms. Results : After Herb therapy, abnormal uterine bleeding was disappeared and recovered the normal menstrual cycle. Conclusion : This clinical case shows that Herb therapy has potentially effective for abnormal uterine bleeding. More clinical data and studies are required for the treatment of abnormal uterine bleeding.