• 동의생리병리학회지
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• 제20권5호
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• pp.1359-1363
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• 2006

It is estimated that 60-80% of menstruating women experience some degree of premenstrual symptom. but there is no accurate treatment guide line about P.M.S. patient who has vomiting. The purpose of this study is to report the effect of oriental treatments for the P.M.S. with vomiting symptom. A 16 years old women, who suffered from vomiting relation with P.M.S., was enrolled in this study. she received oriental treatments such as herbal medicine, acupuncture, cupping therapy for 5 months. The patient was improved in P.M.S. with vomiting symptom. As the result of this study, We found that The patient of P.M.S. with vomiting symptom would be treated in oriental medicine.

• 동서간호학연구지
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• 제16권1호
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• pp.1-10
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• 2010

Purpose: This study tested the effects of Nei-Guan acupressure on nausea, vomiting, and anorexia of lung cancer patients on chemotherapy. Methods: A nonequivalent control group pre-post test design was used to identify the effect of Nei-Guan acupressure on nausea, vomiting, and anorexia of lung cancer patients on chemotherapy. The participants were 60 patients who were admitted to a hospital for chemotherapy from February 1 to October 28, 2009. The patients were randomly assigned to the control group (n=30) or experimental group (n=30). The data were analyzed using Mann-Whitney test. Results: Nausea, vomiting, and anorexia were significantly decreased in the experiment group compared to the control group on the day of discharge from the hospital. However, the levels of nausea, vomiting, and anorexia between two groups were not statistically significant seven days after the discharge. Conclusions: Nei-Guan acupressure is effective in decreasing nausea, vomiting and anorexia of the patients with lung cancer on chemotherapy on the on the day of the discharge while the effectiveness is not certain 7 days after the discharge. Further study is needed to confirm these findings.

• 대한간호학회지
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• 제30권3호
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• pp.720-730
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• 2000

Malnutrition is a common problem in cancer patients. In addition anticancer drugs used in chemotherapy as a major therapeutic mode are famous as the side effect like nausea, vomiting, which lead the patients to malnourished state. This study was to determine the relationship of anorexia, nausea, vomiting and oral intake and identify the influence these side effects on the nutritional status in patients receiving chemotherapy. To assess the nutritional status, anthropometry such as weight, height, body mass index(BMI), body fat proportion, and triceps skinfold thickness, and biochemistry test such as hemoglobin and lymphocyte were measured at the pre- and post- chemotherapy and the readmission time, all three times. During chemotherapy, anorexia, nausea, and vomiting using a VAS or 5-point scale and 24 hour oral intake using a food record were measured daily. Forty-nine patients knowing their diagnosis and receiving chemotherapy were recruited from an oncological ward in a general hospital for 5 months and they were reduced 31 at readmission time for a next chemotherapy. The results were as follows. Most subjects (93.6%) were in the 4th stage of cancer and 57.1% of subjects were in the first or the second chemotherapy. In most subjects(82.6%), their weight was decreased 10.7% than as usual. The degree of anorexia, nausea, and vomiting was significantly higher and the amount of oral intake was significantly less during the chemotherapy than at the pre-chemotherapy. Weight, BMI, triceps skinfold were reduced more at the post- chemotherapy than the pre-chemotherapy and were recovered the nearly same but less level at the readmission time. Body fat proportion was increased at the post chemotherapy and then decreased at the readmission phase. Hemoglobin and the number of lymphocyte were below normal at the pre-chemotherapy and more reduced at the readmission time. Anorexia, nausea, and vomiting were related positively and oral intake was negatively related with nausea and vomiting. The nutritional status at the post- chemotherapy and the readmission time was explained 20% over by the side effect like anorexia, nausea, vomiting and oral intake during the chemotherapy. The significant nutrition predictors at the post- chemotherapy were vomiting and the significant predictors at the readmission time were anorexia, vomiting, and oral intake. These results indicated the patients receiving chemotherapy were continued to deteriorate the nutritional status. Therefore nurse should have knowledge how much the nutritional status can be affected and assess the nutritional status periodically and try to find out the intervention for side effects from the series of chemotherapies.

• 대한핵의학회지
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• 제35권3호
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• pp.198-204
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• 2001

Cyclic Vomiting Syndrome (CVS) is characterized by recurrent, periodic, self-limiting vomiting. However, its pathogenesis is not yet established. We investigated the changes of the cerebral glucose metabolism using F-18 FDG during the vomiting attack and symptom free period in two children with CVS. FDG PET study showed the markedly increased metabolism in both temporal lobes and also in the medulla and cerebellum during the vomiting period. Also, FDG PET showed the decreased metabolism un the parieto-occipital and occipital areas during the vomiting period. The area with decreased metabolism seemed to be related with the region showing abnormalities in EEG and perfusion SPECT studies. We expect that what we observed would be a helpful finding in clarifying the pathogenesis of the CVS.

• The Korean Journal of Pain
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• 제14권2호
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• pp.176-180
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• 2001

Background: The aim of our study was to evaluate the antiemetic effects of intravenous dexamethasone in preventing continuously infused epidural morphine-related nausea and vomiting. Methods: Twenty-seven patients requiring general anesthesia for gastrectomy were enrolled in a randomized, double-blinded, and placebo-controlled study. At the end of surgery, all patients received epidural morphine 3 mg and were connected to an epidural morphine infusion pump for 2 days in order to relieve postoperative pain. Before the morphine injection, the dexamethasone group (n = 12) received IV dexamethasone 10 mg, whereas the saline group (n = 15) received IV saline. The incidence of nausea & vomiting, pruritus, back pain and VAS scores were assessed in the recovery room, and at 24 h and 48 h postoperatively. Results: There was no significant difference in the total incidence of nausea and vomiting, pruritus, back pain or in the VAS scores. However, there was no vomiting and no back pain in the dexamethasone group. Conclusions: Intravenous dexamethasone did not significantly decrease the total incidence of nausea or vomiting in patients receiving continuous epidural morphine for postoperative pain control. However, IV dexamethasone appears to decrease the severity of nausea, vomiting and back pain.

• Clinical and Experimental Pediatrics
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• 제50권4호
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• pp.386-389
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• 2007

주기성 구토증(cyclic vomiting syndrome, CVS)은 예측 불가능한 심한 구토가 특별한 원인 없이 시작되어 각 개인마다 일정한 임상 양상을 보이며 수 시간에서 수일간 지속되다가 저절로 호전되는 것을 반복하는 질환으로서, 그 임상 양상은 편두통과 많은 공통점을 보이며 그 병리생리학적 원인이 편두통과 유사한 것으로 추정되어지고 있다. 저자들은 만 3세 경부터 시작된 발작적이고 반복적인 주기적 구토를 주소로 내원한 5세 남아에서 주기적 구토증을 진단하였으며, 이 환아에서 대규모의 임상 연구를 통해 단독 요법으로 편두통의 예방에 효능이 있음이 인정된 광범위 항경련제인 topiramate(TPM)를 투여하여 그 증상이 호전됨을 경험하고 이를 보고하는 바이다.

• Child Health Nursing Research
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• 제6권1호
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• pp.60-68
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• 2000

The purpose of this study is to assess the effect of progressive muscle relaxation therapy on nausea, vomiting and anxiety experienced by children who were histologically diagnosed as malignancy and have received cancer chemotherapy. Twenty subjects with 10 in experimental group and 10 in control group, between the age of 7 to 12 years participated in this study. All subjects were admitted for inpatients chemotherapy at the S hospital between April to August 1998. The methods used for interventional muscle relaxation were both the 16 items of the progressive muscle relaxation therapy developed by Jacobson and the 4 items of the muscle relaxation therapy by Wolpe. The method for assessing nausea, vomiting was the Index of Nausea and Vomiting by Rhodes et al and that for anxiety was State-Trait Anxiety Inventory for Children by Spielberger. The data was analysed by repeated measures ANOVA and Scheffe test using SAS program. The results were as follows : 1. On measurement of nausea, vomiting, in the experimental group, the mean values of the second and the third measurements showed tendency to slightly decrease compared with the first measurement, but there was no statistically significance. And in the control group, there were no significant differences among first measurement, second measurement and third measurement. Also there was no significant difference in the mean values assessing nausea, vomiting between experimental and control group (F=1.33, p=0.2645). 2. The results assessing state anxiety showed, in the experimental group, progressive decrease in mean values at each measurement, while the control group showed no significant differences between the mean values of each measurement. Also there was statistically significant difference in state anxiety measurements between experimental and control group(F=4.36, p=0.05). In conclusion, muscle relaxation therapy for school-aged children with chemotherapy could not be effective to decrease nausea, vomiting, but it could be effective to decrease anxiety.

• 대한한의학방제학회지
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• 제21권2호
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• pp.158-164
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• 2013

Objectives : "The purpose of this study is to report the effectiveness of Soshiho-tang(小柴胡湯)" on the patient suffered from nausea, retching, vomiting and postprandial fullness. Methods : We diagnosed the symptoms and the signs of the patient as Soshiho-tang syndrome(小柴胡湯證) according to "Treatise on Cold Damage Disease(傷寒論)". We prescribed Soshiho-tang with acupuncture and moxibustion for about 2 weeks. Results : The subjective assessments of the nausea and postprandial fullness had improved. And the frequencies of the retching and vomiting had decreased. Conclusions : We suggest that Soshiho-tang has effectiveness on nausea, retching, vomiting and postprandial fullness in patient diagnosed as Soshiho-tang symptom.

• 성인간호학회지
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• 제26권3호
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• pp.330-340
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• 2014

Purpose: The aim of this study was to identify the effects of auricular acupressure on nausea, vomiting and serum serotonin level in gynecological cancer patients with chemotherapy. Methods: The research was a randomized control group pretest-posttest design. Participants were 26 patients for the experimental group, and 26 patients for the control group. Auricular acupressure in Shen men, Occiput, Stomach and Sympathetic points was administered to those in the experimental group. Data were analyzed using ${\chi}^2$-test, t-test, ANCOVA, and repeated measures of ANOVA. Results: The experimental group had reported significantly lower mean nausea NRS (Number Rating Scale), INVR (Index of Nausea, Vomiting, and Retching), and serum serotonin level than those in the control group. Conclusion: Results of the study show auricular acupressure is an effective nursing intervention for reducing chemotherapy-induced nausea, vomiting and serum serotonin level of gynecological cancer patients.

• 대한간호학회지
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• 제35권1호
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• pp.177-185
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• 2005

purpose: The purpose of this study was to identify the effects of foot reflexology on nausea, vomiting and fatigue in breast cancer patients undergoing chemotherapy. Method: The research was a quasi-experimental study using a non-equivalent pre-post design and was conducted from Jan. 26, to Mar. 20, 2004. The subjects consisted of 34 patients with 18 in the experimental group and 16 in control group. A pretest and 2 posttests were conducted to measure nausea, vomiting and fatigue. For the experimental group, foot reflexology, which was consisted of 4 phases for 40 minutes, was given by a researcher and 4 research assistants. The collected data were analyzed by repeated measures ANOVA using the SPSS WIN 10.0 program. Results: There was a statistically significant decrease in nausea, and vomiting in the experimental group compared to the control group over two different times. In addition, there was a statistically significant decrease in fatigue in the experimental group compared to the control group over two different times. Conclusion: Foot reflexology was effective on nausea, vomiting and fatigue in breast cancer patients receiving chemotherapy in this study. Therefore, foot reflexology can be usefully utilized as a nursing intervention in the field of cancer nursing for breast cancer patients receiving chemotherapy.