The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Pattern of Cerebral Glucose Metabolism on F-18 FDG Brain PET during Vomiting and Symptom Free Periods in Cyclic Vomiting Syndrome

주기성 구토 증후군 환아에서 보인 F-18 FDG PET에서의 뇌 포도당 대사 소견

  • Kim, Yu-Kyeong (Department of Nuclear Medicine, College of Medicine, Seoul National University) ;
  • Lee, Dong-Soo (Department of Nuclear Medicine, College of Medicine, Seoul National University) ;
  • Kang, Eun-Joo (Department of Nuclear Medicine, College of Medicine, Seoul National University) ;
  • Seo, Jeong-Kee (Department of Pediatrics, College of Medicine, Seoul National University) ;
  • Yeo, Jeong-Seok (Department of Nuclear Medicine, College of Medicine, Seoul National University) ;
  • Chung, June-Key (Department of Nuclear Medicine, College of Medicine, Seoul National University) ;
  • Lee, Myung-Chul (Department of Nuclear Medicine, College of Medicine, Seoul National University)
  • 김유경 (서울대학교 의과대학 핵의학교실) ;
  • 이동수 (서울대학교 의과대학 핵의학교실) ;
  • 강은주 (서울대학교 의과대학 핵의학교실) ;
  • 서정기 (서울대학교 의과대학 소아과학교실) ;
  • 여정석 (서울대학교 의과대학 핵의학교실) ;
  • 정준기 (서울대학교 의과대학 핵의학교실) ;
  • 이명철 (서울대학교 의과대학 핵의학교실)
  • Published : 2001.06.28
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Abstract

Cyclic Vomiting Syndrome (CVS) is characterized by recurrent, periodic, self-limiting vomiting. However, its pathogenesis is not yet established. We investigated the changes of the cerebral glucose metabolism using F-18 FDG during the vomiting attack and symptom free period in two children with CVS. FDG PET study showed the markedly increased metabolism in both temporal lobes and also in the medulla and cerebellum during the vomiting period. Also, FDG PET showed the decreased metabolism un the parieto-occipital and occipital areas during the vomiting period. The area with decreased metabolism seemed to be related with the region showing abnormalities in EEG and perfusion SPECT studies. We expect that what we observed would be a helpful finding in clarifying the pathogenesis of the CVS.

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