• 대한수학회보
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• 제50권6호
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• pp.1827-1840
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• 2013

This paper is concerned with the positive steady states of a diffusive Holling type II predator-prey system, in which two predators and one prey are involved. Under homogeneous Neumann boundary conditions, the local and global asymptotic stability of the spatially homogeneous positive steady state are discussed. Moreover, the large diffusion of predator is considered by proving the nonexistence of non-constant positive steady states, which gives some descriptions of the effect of diffusion on the pattern formation.

• 호남수학학술지
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• 제17권1호
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• pp.141-147
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• 1995

We find a method finding the steady-state probabilities of M/M/3/3 retrial queueing system.

• Bulletin of the Korean Chemical Society
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• 제27권10호
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• pp.1618-1622
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• 2006

Bacteriophage T7 gp4A' is a ring-shaped hexameric DNA helicase that catalyzes duplex DNA unwinding using dTTP hydrolysis as an energy source. To investigate the effect of single-stranded DNA (ssDNA) on the kinetic pathway of dTTP hydrolysis by the T7 DNA helicase complexed with ssDNA, we have first determined optimal concentration of long circular M13 single-stranded DNA and pre-incubation time in the absence of $Mg^{2+}$ which is necessary for the helicase-ssDNA complex formation. Steady state dTTP hydrolysis in the absence of $Mg^{2+}$ by the helicase-ssDNA complex provided $k_{cat}$ of $8.5\;{\times}\;10^{-3}\;sec^{-1}$. Pre-steady state kinetics of the dTTP hydrolysis by the pre-assembled hexameric helicase was monitored by using the rapid chemical quench-flow technique both in the presence and absence of M13 ssDNA. Pre-steady state dTTP hydrolysis showed distinct burst kinetics in both cases, indicating that product release step is slower than dTTP hydrolysis step. Pre-steady state burst rates were similar both in the presence and absence of ssDNA, while steady state dTTP hydrolysis rate in the presence of ssDNA was much faster than in the absence of ssDNA. These results suggest that single-stranded DNA stimulates dTTP hydrolysis reaction by T7 helicase by enhancing the rate of product release step.

• 한국수의병리학회지
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• 제2권2호
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• pp.127-138
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• 1998

Transmissible venereal tumor(TVT) is a naturally occurring contagious neoplasm which can be transmitted by mechanical contact during mating in dogs and transplanted as intact viable cells to dogs and other members of canine family such as coyotes, jackals, wolves, and foxes. The incidence of this tumors tends to increase in Korean native Jindo dogs. This is probably due to the high density and unrestrained management system. With time, TVT reaches the maximum size and then tends to regress spontaneously unless individuals are immunologically compromised. It consists of different types of cells depending on the stage. In this study, 10 tumors were selected from Jindo dogs. These were histologically calssified into three stages; progressive, steady-state, and regressive. Mitotic figures were counted, and their histological appearance at each stage is compared with their DNA ploidy. Histologically, 5 tumor cases were calssed as the progressors, 3 cases as the steady-state tumors, and 2 cases as regressors. Progressors were composed of round cells with large nuclei containing conspicuous nucleoli and frequent mitotic figures. A few spindle-shaped cells and inflammatory cells including mainly lymphocytes, a few neutrophils and macrophages were also seen. In the steady-state tumors, there was an increased number of spindle shaped cells and mitotic figures were rare. Six tumors were diploid and four were aneuploid with the variation coefficient of 7.02. Two of five progressive tumors were aneuploid. Two of three steady-state tumors were aneuploid while both tumors at the regressive stage were diploid. Progressive and steady-state tumors had a much larger S/G2M fraction and a higher mitotic index than regressive tumors. Two tumors which persisted for more than one year were aneuploid. These results suggest that the progressive and steady-state tumors had more active cell division than the regressive neoplasms.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 제37회 하계학술대회 논문집 D
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• pp.1854-1855
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• 2006

In this paper, the Takagi-Sugeno (TS) fuzzy state estimation scheme, which is suggested for a steady state estimator using standard Kalman filter theory with uncertainties. In that case, the steady state with uncertain can be represented by the TS fuzzy model structure, which is further rearranged to give a set of uncertain linear model using standard Kalman filter theory. And then the unknown uncertainty is regarded as an additive process noise. To optimize fuzzy system, we utilize the genetic algorithm. The steady state solutions can be found for proposed linear model then the linear combination is used to derive a global model. The proposed state estimator is demonstrated on a truck-trailer.

• 전기학회논문지
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• 제59권10호
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• pp.1748-1753
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• 2010

This paper suggests an improved technique to establish the modeling regarding steady and transient state on three phase-in one cryostat type HTS(High Temperature Superconducting) cable. The proposed modeling is established using EMTP/ATPDraw and TACS and MODELS provided by that. It has higher accuracy than the conventional method, as the actual HTS cable is modelled. Steady and transient state analysis performed by EMTP/ATPDraw calculate the current of conductor, shield and former, respectively. In case of the transient state modeled quench state occurred by a single line-to-ground fault, current of conductor shield and former are also calculated, respectively. Especially, various fault resistances and angles are considered to improve the reliability during transient state analysis. Analysis results reveal that the proposed technique improves the accuracy of modeling.

• Journal of Microbiology and Biotechnology
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• 제8권1호
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• pp.8-13
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• 1998

Animal cells in culture typically convert most of the glucose they consume into lactate. The accumulation of lactate, however, is commonly cited as one of the factors that inhibit cell growth and limit the maximum cell concentration that can be achieved in culture. The specific production of lactate and the amount of glucose converted to lactate can be reduced when cells are grown in a fed-batch culture in which the residual glucose concentration is maintained at low levels. Such a fed-batch culture was used to grow and adapt hybridoma cells into a low-lactate-producing state before changing into continuous culture. The cells reached and maintained a high viable cell concentration at steady state. In a similar manner, cells that were initially grown in batch culture and a glucose-rich environment reached a steady state with a cell concentration that is much lower. The feed composition and dilution rates for both cultures were similar, suggesting steady state multiplicity. From a processing perspective the desired steady state among those is the one with the least metabolite production. At such seady state nutrient concentration in the feed can be further increased to increase cell and product concentrations without causing the metabolite inhibitory effect typically seen in a cell culture. Controlling cell metabolism in a continuous culture to reduce or eliminate waste metabolite production may significantly improve the productivity of mammalian cell culture processes.

• 한국지반공학회논문집
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• 제38권6호
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• pp.29-39
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• 2022

도심지 원형 수직구 굴착 시 주변 지반의 침하는 포장 하부에 설치된 인프라시설의 안정성 뿐만 아니라 상부구조의 안정성에 큰 영향을 미친다. 배면지반의 침하량을 예측하는 방법은 지반조건, 벽체 변위, 해석 방법 등에 따라 달라지므로 근접시공 설계자는 합리적으로 침하량을 예측해야한다. 본 연구에서는 3차원 유한요소해석을 활용하여 굴착심도별로 지하수의 침투에 따른 영향을 고려하기 위해 비정상류, 정상류, 지하수를 고려하지 않은 조건으로 배면지반의 침하와 벽체의 변위 그리고 토압분포를 검토하였다. 수치해석결과, 배면지반의 침하량과 침하영향범위는 비정상류 상태가 정상류 상태보다 크게 발생하였으나 벽체의 수평변위는 반대로 정상류 상태가 비정상류 상태보다 크게 나타났다. 침하량의 크기는 굴착 깊이에 따라 다르게 나타났으며 굴착 깊이 별로 토사층에서 가장 크고 풍화암층, 연암층 순으로 감소하였다. 또한 수압을 포함한 수평응력값을 기존의 Rankine 토압식과 비교했을 때 토사지반에서는 유사한 경향을 보이나 암반층에서는 수치해석 결과보다 작은 토압형태가 나타남을 확인 할 수 있었다.

• 대한산업공학회지
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• 제8권2호
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• pp.15-21
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• 1982

This paper offers an alternative to the common probability generating function approach to the solution of steady state equations when a Markovian queue has a multivariate state space. Identifying states and substates and grouping them into vectors appropriately, we formulate a two - dimensional Markovian queue as a Markov chain. Solving the resulting matrix equations the transition point steady state probabilities (SSPs) are obtained. These are then converted into arbitrary time SSPs. The procedure uses only probabilistic arguments and thus avoids a large and cumbersome state space which often poses difficulties in the solution of steady state equations. For the purpose of numerical illustration of the approach we solve a Markovian queue with one server and two classes of customers.

• 한국환경과학회지
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• 제4권1호
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• pp.71-80
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• 1995

생화학적 산소요구량(BOD) 및 용존 산소(DO)을 이용하여 여러구간이 있는 강에 대한 이산 상태공간모델은 설정하였다. 상호작용 예측방법을 이용하여, 상태변수에 시간지연이 존재하는 대규모 시스템에 적용가능한 계층적 최적화 방법을 기술하였다. 정상상태 오차를 해석적으로 구하고, 상수 목표티 추적문제에 있어서 정상상태 오차가 발생하지 않을 필요충분조겆을 규명하였다. 수질오염 모델에 대한 컴퓨터 모사를 통하여 기술한 알고리듬의 타당성을 확인하였다.