• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.23-30
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• 2014

Purpose: The present study was aimed to figure out the correlation amongst the evaluation methods for critical micelle concentration, surface tension and protein cleaning efficacy to evaluate cleaning efficacy of contact lens care products. Methods: The critical micelle concentration of surfactants and the actual concentration of surfactants in contact lens care solutions were investigated by employing references published and related information. Surface tension of contact lens care solutions was measured by surface tension device at $25{\pm}1^{\circ}C$, and contact lenses made of lotrafilcon A, comfilcon A and balafilcon A were washed with contact lens care solutions after the incubation in artificial tears for 14 days and their cleaning efficacy was compared. Results: Among the 22 contact lens care products, 9 products provided the label of the concentration of surfactant, and 7 products showed higher concentration of surfactant than the critical micelle concentration reported in references. As a result of measuring surface tension, the surface tension of lens care products for soft contact lens was generally lower than other care products. When examined the removal effect of protein deposited on lens surface, it was known that the care products having lower surface tension showed higher protein removal efficiency. Conclusions: The surface tension is low when surfactant concentration in contact lens care solutions is high, and the removal effect of protein deposited is accordingly increased with the decrease of surface tension. Thus, these indicate the correlation amongst the evaluation methods for cleaning efficacy.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.1
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• pp.11-21
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• 2016

Purpose: The aim of this study was to analyze the difference in tear film stability according to the wearing time when wearing clear and circle soft contact lens(circle lens) made of same material. Methods: The clear and circle contact lenses of hilafilcon B and nelfilcon A materials were respectively applied on the subjects classified as normal and dry eyes depending on their tear volume, and their tear film stability was investigated by measuring the non-invasive tear film break-up times, lens centration and the first appearing area of tear breakup after 30 mins and 6 hrs of lens wearing. Results: Non-invasive tear film breakup time significantly reduced with increase of the wearing time for normal and dry eyes when wearing clear and circle contact lenses. The starting ratio of tear film break-up was higher at the peripheral area of clear and circle lenses in all two different materials, and higher at the peripheral area of dry eyes than normal eyes. Starting ratio of tear film break-up was higher at the peripheral area of nelfilcon A lenses compared with hilafilcon B lenses, however, its change with the increase of wearing time showed a different aspect. The number of tear film break-up per unit area when wearing circle lenses of nelfilcon A increased at the central area with the wearing time while its number was higher at the peripheral area when wearing circle lenses of hilafilcon B. The centration of clear lenses made of two materials was closer to pupil compared to circle lenses with the increase of wearing time, however, a larger decentration was shown in dry eyes compared with normal eyes. Conclusions: The research revealed that an effect on tear film stability may be changed by clear lenses as well as circle lenses with coloring process according to the increase of wearing time, and the factors affecting on tear film stability may also vary depending on lens materials. Thus, the appropriate lenses should be selected by the consideration of lens material as well as coloring method/dyes according to the wearers' habit such as daily wearing time and wearing period when trying to wear clear and circle lenses.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.2
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• pp.179-188
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• 2014

Purpose: The present study was aimed to investigate the cleaning efficacy of multi-purpose solutions containing different types and content of surfactants and their effect on the visible light transmittance of soft lens. Methods: Soft lenses made of different materials (etafilcon A and hilafilcon B) were deposited tear proteins by using the artificial tear and then compared the resulting cleaning efficacy and visible light transmittance after cleaning the lens with 6 types of multi-purpose solutions containing different content of surfactants. Results: The cleaning efficacy of multi-purpose solutions was variously shown as approximately 23~43% according to the active concentration of surfactants and surface tension in multi-purpose solution when etafilcon A lens cleaned with rubbing. The highest cleaning efficacy was detected when cleaned with the multi-purpose solution containing hydrogen peroxide besides surfactant however, the amount of remaining protein was still high on the lens. After washed with multi-purpose solution, the visible light transmittance of lens was in 89.8 to 90.8%. The amount of protein deposited on hilafilcon B lens was very small compared with it on etafilcon A lens even though it was incubated in artificial tears for 7 days, which showed 5~10% of protein amount in etafilcon A lens and the decrease of visible light transmittance was also not significant. In case of rubbing with multi-purpose solution, the cleaning efficacy on hilafilcon B lens was in 45.4 to 67.4% however, the order of cleaning efficacy of multi-purpose solution was different from it on etafilcon A lens. The visible light transmittance of hilafilcon B lens has been restored to the level of new lens. Conclusions: From the result, it is concluded that the appropriate multi-purpose solution should be selected according to the lens material and the amount of protein deposit on the basis of understanding surfactants and active principle for proper care of protein deposit on soft lens and the cleaning with rubbing is more efficient for lens care regardless of manufacturer's guideline.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.1
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• pp.43-49
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• 2015

Purpose: This study was to compare the habitual soft contact lens wear to recommended wearing schedule for subjects and suggest a clinical guideline for prescribing contact lens. Methods: 611 adults (39 men and 572 women) with contact lens experience took part in this study. The survey collected information about current wearing schedule (hours/day and days/week), types of lenses worn and awareness of recommended wear schedule. Results: The subjects wore the daily contact lens for $7.97{\pm}3.60$ hours/day in average. Of these, 247 subjects (40.4%) exceeded the recommended wear schedule and 36 (5.9%) wore for over 15 hours. It turned out that subjects with 3-month extended contact lenses and the ones with the conventional daily wear wore for $9.79{\pm}2.68$ hours and $8.98{\pm}3.30$ hours/day, respectively. For subjects wearing contact lenses longer than five days/week it tended to wear for over 9 hours. Those who were aware of the wear schedule were 293 (48.0%), and those not were 318 (52.0%). 56.7% of subjects who were aware of the wear schedule respected the recommendation whereas only 22.3% of those unaware of it were found to respect it. The possibility to respect the wear schedule was 4.55 times higher when wearers were aware of it. Conclusions: Korean office workers wearing contact lenses wore for $7.97{\pm}3.60$ hours/day. 247 (40.4%) of subjects wore contact lens longer than recommended wear schedule. This implies that it will need to educate contact lens wearer about recommended wear schedule and advice for the long time wearer.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.43-49
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• 2014

Purpose: The physical and optical characteristics of hydrophilic contact lens polymerized with addition of glycerin and PVP(polyvinylpyrrolidone) in the basic hydrogel contact lens material were evaluated. Methods: This study used glycerin and PVP(polyvinylpyrrolidone) with the cross-linker EGDMA (ethylene glycol dimethacrylate), HEMA (2-hydroxyethyl methacrylate) and the initiator AIBN (azobisisobutyronitrile) for copolymerization. Results: Measurements of the physical characteristics of the copolymerized material including PVP(polyvinylpyrrolidone) showed the refractive index of 1.4382~1.4288, tensile strength of 0.3446~2542 kgf and water content and contact angle of sample showed the increase of 13.49% and decrease of 21.44% independently. And also, the physical characteristics of the copolymerized material including glycerin showed the refractive index of 1.4330~1.4328, tensile strength of 0.2974~0.2854 kgf, water content 35.58~36.53% and contact angle of sample showed the decrease of 37.64%. Conclusions: Based on the results of this study, the produced copolymers is suitable for conventional lens with high wettability. Also, glycerin minimized the changes of water content and refractive index at the same time, increased the wettability of the hydrogel lens materials.

• The Korean Journal of Vision Science
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• v.20 no.4
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• pp.469-482
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• 2018

Purpose : We investigated the change of spherical and comma aberrations after wearing aspheric soft contact lens (ASCL) in young myopes. Methods : Fifty young myopes ($23.15{\pm}1.70years$, spherical equivalent: $-2.90{\pm}1.75D$) were recruited and refractive errors were corrected using ASCL (Biotrue, Bausch+Lomb, USA). High order aberrations were measured in the 4 mm pupil size using the wavefront analyze and pupil sizes were measured with a pupillometer at the modes of scotopic condition (light off) at 3.5 m in the 100 lx illuminance condition. Results : Spherical aberrations and coma aberration of the 20s myopes were $0.026{\pm}0.031{\mu}m$ and $0.078{\pm}0.039{\mu}m$ respectively, and $0.019{\pm}0.026{\mu}m$ and $0.082{\pm}0.038{\mu}m$ after ASCL wear that spherical aberration was decreased and coma aberration was increased. However, spherical aberration was decreased in the 68% of the subject have positive spherical aberration, and increased in the 11% of the subject have negative spherical aberration. Coma aberration was increased in the 53% of the subject, did not change in the 19% of the subjects, and decreased in the 28% of the subject. Spherical aberration was not different with the refractive errors in low and moderate myopies, however, coma aberrations was higher in the higher myopes. Conclusion : In a scotopic condition without accommodation stimuli, spherical aberration is decreased after wearing ASCL, however in the subject have negative spherical aberration spherical aberration could be increased, and which is thought to be the influence of contact lens design and pupil size.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.2
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• pp.137-144
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• 2010

Purpose: This study was to evaluate the clinical performance of 1-Day disposable toric soft contact lenses (TSCL) and to compare the visual performance with glasses and TSCL. Methods: In a two-week investigation of 'prism ballast' designed TSCL, occular refractions in 15 (30 eyes) healthy subjects were within the range of -2.75 D TO -8.00 D spherical power and -0.75 DC to -2.25 DC cylinderical power (with-the-rule). Subjects were assessed the clinical performance (orientation, centration, movement, tightness, rotation recovery, symptoms) of TSCL and compared binocular vision and contrast sensitivity with corrected glasses and TSCL at initial and two-week follow-up visits. Results: The prism-ballast design TSCL achieved better orientation, rotation recovery and symptoms over 2 week period. There was no statistically significant difference between spectacles and TSCL with respect to measuring binocular vision and contrast sensitivity. Conclusions: The clinical performance was good with prism-ballast design toric soft contact lenses. Evaluation of binocular vision and contrast sensitivity did not show the differences between spectacles and TSCL correction. This study suggests that TSCL wearers can be achieved similar visual performance for spectacles wearers.

• Journal of the Korean Applied Science and Technology
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• v.36 no.1
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• pp.305-311
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• 2019

The acrylic copolymer was designed and prepared for soft lens with high content. The copolymers were prepared using 2-hydroxyethyl methacrylate(HEMA) as a monomer and ethylene glycol dimethacrylate(EGDMA), glycerol dimethacrylate(GD), or glycerol 1,3-diglycerolate diacrylate (GDD) as a cross linking agent. The water content for high water content lens was 46%, which was higher compared to general purpose of 36%. The contact angle decreased from 38.6 to 34.4, which appears hydrophilic surface. The tensile strength decreased from 0.1 Mpato 0.08, then again to 0.05 as hydrophilic properties of cross linking agents increased. No phase separation was observed in the cross section of lens using scanning electron microscope. The real-time infrared technique was used in photo-polymerization. The initial polymerization rate increased from 0.6 to 0.9, depending on crosslinking agent.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.1
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• pp.51-60
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• 2011

Purpose: This study was to investigate visual performance and subjective satisfaction with multifocal soft contact lenses at near works in university students. Methods: In a cross-over study design, 26 students (6 male, 20 female) who did not have any ocular disorder with at least 20/20(1.0) binocular vision were fitted with singlevision lenses (SofLens$^{TM}59$, Bausch + Lomb Co. USA) or multifocal lenses (SofLens Multifocal, Bausch + Lomb Co. USA). After 2 weeks, visual performance assessments included visual acuity, stereoacuity and contrast sensitivity function at distance and near. Near point of accommodation, accommodative facility, near point of convergence, vergence facility and near range of clear vision at near were examined. Students' satisfaction and preference were measured using survey questionaries. Results: Subjects maintained at least 20/20 binocular vision with multifocal and single-vision lenses at distance and near. There was no difference between multifocal and single-vision lenses in stereoacuity, contrast sensitivity function and vergence facility at far and near. The near point of accommodation, accommodative facility, near point of convergence and the near range of clear vision with multifocal lenses were better than single-vision lenses. On the survey questionaries, subjects reported that they preferred and satisfied with multifocal lenses with near works, and single-vision lenses with distance works. Conclusions: The majority of university students preferred multifocal to single vision lenses because multifocal lenses provided better visual performance at near works. This study suggests that multifocal lens is helpful for young adult in prolonged near works.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.117-124
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• 2015

Purpose: The purpose of this study was to compare the accommodative function of young adult in their 20s wearing monovision, modified monovision, and aspheric multifocal contact lenses at near task. Methods: Thirty young adults ($23.53{\pm}2.37years$) were fitted with monovision, modified monovision (the application of single vision contact lenses and center-near low addition aspheric multifocal contact lenses), and aspheric center-near multifocal contact lenses. After wearing these modalities during a week for adaption, and after watching visual display at computer for inducing accommodative pressure for 1 hour. The following assessments of accommodative function were made: contrast visual acuity (VA) at distance and near; accommodative response; near accommodative facility; and negative relative accommodation (NRA)/positive relative accommodation (PRA). All measurements were carried out binocularly. Results: In binocular distance VA with contrast of 10%, monovision was the worst among the four modalities (p=0.005). In accommodative response at 1 m (1.00 D), monovision was the lowest (p<0.05) and accommodative response at 40 cm (2.50 D) with monovision was lower than that of modified monovision and multifocal contact lens (p<0.05). We also found that there were no significant differences in accommodative facility and NRA/PRA among the four modalities. Conclusions: In young adult (20s), monovision with low add reduced the accommodative response at near task, however, modified monovision and multifocal lens with center-near type did not affect accommodative relaxation.