• Natural Product Sciences
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• 제26권4호
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• pp.279-282
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• 2020

Chemical investigation of the methanol extract of Koordersiodendron pinnatum Merr. leaves resulted a new naphthalene derivative, (Z)-4-(tetradec-3-enyl)naphthalene-1,2,7-triol (1), together with three known compounds, ��-sitosterol (2), 20-epibryonolic acid (3), and scopoletin (4). The structure of the new compound was elucidated based on spectroscopic evidence. The isolated compounds (1-4) were tested their cytotoxic activities against the P-388 murine leukemia cell line and compound 1 has highest activity with IC50 1.94 μM.

• 한국임상약학회지
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• 제20권2호
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• pp.107-113
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• 2010

서 론: 중환자실에서 집중적 인슐린 요법에 의한 평균혈당강하는 사망률을 감소시키는 것으로 나타났으나 이로 인한 저혈당 및 혈당변동은 새로운 문제로 대두되고 있다. 본 연구에서는 혈당과 관련한 여러 요인들이 사망에 미치는 영향을 규명하고 적정 혈당치를 확인하고자 하였다. 연구방법: 2008년 2월부터 7월 사이인 6개월 동안 서울아산병원 외과계 중환자실에서 4일 이상 재실한 18세 이상의 성인 환자를 대상으로 전자 의무기록 조사를 통해 후향적으로 연구가 진행되었다. 연구를 위해 환자의 인구학적 특성, 수술의 종류, 중환자실에서의 재실기간, 사망여부, 스테로이드 사용 유무, 기계적 인공호흡기의 사용유무, 신대체요법의 사용유무, 혈당치, 재실기간 중 스테로이드 사용유무와 인슐린 양, 입원 후 첫 24시간 동안의 포도당 주입속도, 입원 후 2일 이내와 그 이후에 발생한 균혈증 감염, APACH II와 SOFA 점수를 조사하였다. 혈당수치는 각각의 환자에서 중환자실 입실 후 가장 처음 측정된 혈당, 재실기간 중 가장 높은 혈당과 가장 낮은 혈당수치를 조사하였고 중환자실 전체 재실기간 동안 혈당수치의 평균과 변동계수를 계산하였다. 이상의 혈당관련지표를 포함한 인자들이 일차 종속변수인 사망에 어떠한 영향을 주는지를 환자를 생존군과 사망군으로 나누어 분석하였고 ROC (receiver operator characteristic) 곡선을 사용하여 혈당지표와 APACH 및 SOFA 점수의 cut-off치를 구하여 이로부터 단변량 및 다변량 분석을 시행하였다. 결 과: 연구에 포함된 환자는 170명 이었고 그 중 23명이 연구 기간 중 중환자실에서 사망하였다. 생존자에 비해 사망자의 최대혈당은 유의적으로 높았고 최소혈당치는 유의적으로 낮아 높은 변동계수를 보였다. ROC곡선으로부터 산출된 혈당치들의 cut-off 수치는 최소혈당치 70 mg/dL, 변동계수 25%, 최대혈당치 250 mg/dL, 평균혈당치 150 mg/dL이었다. 다변량분석에서 최소혈당이 70 mg/dL 보다 큰 경우가 낮은 경우에 비해 오즈비가 0.922(95% 신뢰구간 0.881-0.965)로 유의성 있게 낮았으며 변동계수가 25% 보다 높은 집단의 경우 그보다 낮은 집단에 비해 오즈비가 1.121(95% 신뢰구간 1.017-1.236)로 유의성 있게 높았다. Kaplan-Meier 생존분석 결과 최소혈당치 70 mg/dL와 변동계수 25%에 따라 생존기간에 유의성 있는 차이가 나타났다.(각각 P < 0.001, P < 0.05) 결 론: 고혈당 발생의 감소뿐 아니라 최소혈당치를 70 mg/dL 이상으로 유지하면서 변동을 최소화하는 것이 외과계 중환자실에서의 사망률감소를 위한 중요한 요인임을 알 수 있었다.

• 방송공학회논문지
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• 제28권2호
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• pp.213-229
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• 2023

본 논문에서는 가상환경에 위치한 청취자의 움직임에 대응하여 실시간으로 6DoF 공간음향을 제공하는 공간음향 렌더링 시스템에 대해 소개한다. 본 시스템은 MPEG-I Immersive Audio CfP 대응을 위하여 MPEG-I AEP를 개발환경으로 사용하여 구현되었으며 인코더와, 디코더를 포함하는 렌더러로 구성된다. 인코더는 인코더 입력 포맷(EIF) 파일에 포함된 가상공간 장면의 공간적 오디오 파라미터와, SOFA 파일로 제공되는 음원의 지향성 정보 등의 메타데이터를 오프라인으로 부호화하여 비트스트림으로 전달하는 역할을 하며, 렌더러는 전달된 비트스트림을 수신하여 청취자의 위치에 따라 실시간으로 6DoF 공간음향 렌더링을 수행한다. 개발된 렌더링 시스템에 적용한 주요 공간음향 처리 기술로는 음원 효과 및 장애물 효과 처리 기술이 있으며, 그 외 시스템 동작에 필요한 기술로는 도플러 효과 및 음장효과 처리 기술 등이 있다. 개발된 시스템에 대한 성능평가 결과로서 자체 주관평가 결과를 소개한다.

• 한국실내디자인학회논문집
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• 제27권2호
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• pp.128-142
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• 2018

This study is to analyze a case of US Bravo TV program, Interior therapy with Jeff Lewies, based on analytical psychology by Carl Jung, to understand characteristics of interior therapy in psycho-therapeutic viewpoint. Case study among descriptive observation approaches was chosen as a study method while the study range was set as 8 episodes in 2012 and 8 episodes in 2013. As a result of study, future application of therapy to domestic interior design was suggested as 3 types the following; a) Paranoid and storage disorder type that pursues space design by horizontal elements with a sense of comfortable, starting from throwing things away, and suggests whiteness based on desire to be cleaned; b) Individual taste type starting from give and take between members and recognizing one another. e.g., aligning the U-shaped sofa and giving a sense of comfort by using the achromatic colors; and c) Workroom type involved with the face-to-face type of space design and arrangement of mild grey and brown colors. Finally, this study has its significance in suggesting the direction for new occupational clusters in the field of domestic space design (interior, architecture, environment design, etc.), which could be utilized as a basic data for training program development to foster interior therapy professionals.

• 대한가정학회지
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• 제42권11호
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• pp.31-45
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• 2004

The purpose of this study was to provide basic information about the facility planning to reduce elderly isolation and to improve their rehabilitation ability. Four re%archers observed the using behavior of the elderly residents in the corridor and lounge of 5 facilities. The results of the study were as follows. The using rate of the lounge wis higher than that of the corridor since most of the elderly were controlled by the staffs at the lounge. The facility could decrease the crowd of the lounge by arranging the sofa at the corridor-especially surrounding the atrium. The use rate in the lounge was very dependent on the time of the day, because its use was influenced mainly by daily schedule, and this resoled in it being largely inactive most of the time. A counter plan is needed to encourage natural interaction among the elderly. Individual or small group activities are required in addition to the regular programs. Since the furniture arrangements_(sofas and tables) at the corridor could induce elderly isolation and inactivity, various equipments should be arranged for the self-controlled activities. The indirect participation in the regular activities, which are usually conducted in the lounge, should also be considered in the corridor so that the elderly could observe them at any places.

• 한국가구학회지
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• 제28권4호
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• pp.326-331
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• 2017

The survey of consumers' recognition of home furniture colors was conducted targeting 32 males and 68 females from 20's to 60's. The results are as follows. The first, in terms of colors, when they were asked of where was the most important place in a house, the first place they thought of was the color of wallpaper and the second was the color of furniture. The second, in terms of home furniture colors, a sofa was put the most importance on and a living room dresser was the next. The third, they preferred natural wood color as home furniture and the next color was achromatic colors. The forth, the most preferred wood color was a walnut and the next was a ginkgo tree color. The fifth, the most preferred color was white and the next was tertiary colors when they were asked to paint their home furniture. The sixth, 88% participants in the survey responded that home furniture colors would much influence on our lives. In conclusion, most consumers recognize the importance of furniture colors and they prefer the use of hardwood for a natural feeling as long as they can afford.

• 한국주거학회논문집
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• 제16권2호
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• pp.91-98
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• 2005

The purpose of this study was to explore behaviors of spatial usages such as patterns of spatial usages, perception on residential spaces, and furniture arrangement. A questionnaire survey and interview were adopted in this study, and 146 residents living in apartment with 3 bedrooms, stairway access, and 3-bay style in the City of Gwangju. The major findings of this study were that 1) dining-kitchen (DK) was conceived and used as a space not only for dining but also family gathering and guest reception. Dining table without refrigerator was frequently found in furniture arrangement of DK, and refrigerator has been relocated in utility room facing DK. The results imply the need for social interaction that has been growing. Anbang (master bedroom) has been perceived and used as couples' private area, aside from the traditional function of family interaction. A coordination of both bed and wardrobe out of different furniture arrangements was popular in anbang. Living room was used as a multi-purpose room carrying out various activities such as family gathering, guest reception, and housekeeping. Sofa and cabinet were the most common furniture arrangement in living room. The research results are a basis for development residential open housing system.

• 한국주거학회논문집
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• 제5권2호
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• pp.99-108
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• 1994

The purpose of this study was to present basic data for better space plan of the apartment housing. It attempted to examine the possession and space usage of furniture and housing goods in three type floor plan. It also studied in relation to socidemographic variables and physical variables. The major findings were as follows :1) Housewife age, educational level, family income, number of family members were affected variables to the possession of housing goods and furniture except furniture possession to housewife age.2) It appeared similarity in the furnishing of housing goods and furniture in case of same floor plan.3) Generally, the space of living room was used often in furnishing of furniture and housing goods. 4) Linear arrangement of sofa set and corner arrangement of Anbang furniture are a tendency to get a effective space for activities in living room.5) The size of floor plan space was the most powerful variable to explain the possession and space usage of housing goods and furniture.6) The scarce of space result in pressing the household living space hard. The storage space should be planned and chosen after consideration of human factors according to the tastes, character of the users, and the space factors according to the composition of unit plan and the size of each living space. In case of the small size plan, particularly, it needed to the Built-in furniture as a effective method.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2004년도 춘계학술발표대회 논문집
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• pp.49-55
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• 2004

The purpose of this study was to explore typical behaviors of spatial usages such as patterns of spatial usages, perception on residential spaces, and furniture arrangement. A questionnaire survey and interview were adopted in this study, and 146 residents living in apartment with 3 bedrooms, stairway access, and 3-bay style in the City of Gwangju. The major findings of this study were that 1) dining-kitchen (DK) was conceived and used as a space not only for dining but also family gathering and guest reception. Dining table without refrigerator was frequently found in furniture arrangement of DK, and refrigerator has been relocated in utility room facing DK. The results imply the need for social interaction that has been growing. Anbang (master bedroom) has been perceived and used as couples' private area, aside from the traditional function of family interaction. A coordination of both bed and wardrobe out of different furniture arrangements was popular in anbang. Living room was used as a multi-purpose room carrying out various activities such as family gathering, guest reception, and housekeeping. Sofa and cabinet were the most common furniture arrangement in living room. The research results are a basis for residential open housing system.

• 한국가구학회지
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• 제27권4호
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• pp.343-351
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• 2016

This study was jointly conducted by the department of nursing science in a college of natural sciences and the furniture design department in the art and physical education to research the critical factors for the furniture development for the Elderly in consideration of the surging number of senior citizens not only in Korea but also globally. On the basis of the Elderly's physical and mental characteristics investigated by the department of nursing science, the furniture design guideline for the Elderly was presented. The following points should be considered at designing the furniture for the Elderly. First, multiple functions like chair with removable toilet bowl and part lighting in bed are advantageous. Second, the dimension of furniture such as chair, bed and sofa should be ergonomically thought in terms of structure for the Elderly's convenience. Third, the bright and vivid color of furniture should be chosen from the aspect of the design, while the different kinds of blue should be avoided. Small patterns and high glossy are not recommendable, but various kinds of feelings in different shapes are suggested. Forth, the material should contribute to the fracture prevention and for that sponge, fabric and leather smoothing the surface of furniture are recommendable as the finishing treatment in a wide variety of colors.