• Title/Summary/Keyword: skin improvement

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Preparation of Liquid Crystalline with Gemini Surfactant (제미니형 계면활성제를 사용한 액정기술의 제조방법)

  • Zhoh Choon-Koo;Kim In-Young;Han Chang-Giu
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.3 s.47
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    • pp.369-375
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    • 2004
  • In this study, liquid crystalline (LC) is formed using Gemini surfactant (GS) type and moisturizing effect in vivo is measured. $3.0\;wt\%$ of sodium dicocoyl ethylene diamine (PEG)-15 sulfate (SCD-PEG-15S) is used as GS and $4.0\;wt\%$ of hydrogenated dimer acid esters (HDAE) as booster. For stabilizers, $2.0\;wt\%$ of behenyl alcohol (BA) and $1.0\;wt\%$ of Iyso-lecithin (LyL) are utilized. It is stabilized in pH from 4.0 to 10.5 and the best condition is in pH 6.5. The value of viscosity is $8,000\pm500$ cP. The most excellent particles are formed within the range of 4.0 to 15.5 um. Formed LC is observed around LC particles using polarization microscope. It is also observed that lamellar gel network structure is formed around LC particles. Moisturizing effect is improved by $13.6\%$ (P<0.05) compared to control when measured 30 min later after coating samples. After 1 h, moisturizing effect is improved by 1$12.6\%$ (P<0.05) than control while showing $28.3\%$ (P<0.05) of improvement after 4 h. These results may be caused from that manufactured LC forms lamellar structure so that it has better water-holding ability and absorbance of oil increases. This formula could be utilized by delivery system (DS) on skin so that this technology can be applied for manufactuing pharmaceuticals and cosmetics.

Evaluate efficacy of fermented soybean(Bio-Peptone)cream in pruritus : Randomized, double-blinded, placebo-controlled, parallel-group clinical experiment study (피부 가려움증에 대한 대두(大豆) 발효물(Bio-Peptone)크림의 유효성 평가 : 무작위 배정, 양측 눈가림, 위약크림 대조, 평행 설계 연구)

  • An, Jae-Hyun;Jung, Hyun-A;Kim, Eun-Ju;Kim, Ae-Jung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.33 no.3
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    • pp.27-44
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    • 2020
  • Objectives : The authors conducted randomized, Double-blinded, and placebo-controlled parallel-group clinical experiment study to evaluate efficacy of fermented soybean(Bio-Peptone)cream in pruritus. Methods : The research had been conducted for 4 months from the date of IRB approval(May 26 in 2017) to Sept 2017. The experiment started by randomly distributing 25 subjects with pruritus into experimental group and control group, respectively. The experimental group applied fermented soybean(Bio-Peptone)cream twice a day, in the morning and evening, for one week on itchy area. The effect of the product was evaluated by comparing the PSS(Patient subjective score), moisture level by measuring skin moisture content(Corneometer) and transepidermal water loss(Tewameter), and the Korean version of Skindex-29(index of quality of life improvement) before applying the cream, after applying the cream for one week and after stop applying the cream for one week. The control group conducted identical experiment with the experimental group, except the control group applied placebo instead of the fermented soybean(Bio-Peptone)cream. Results : Pruritus, criterion of the first validation testing, indicates fermented soybean(Bio-Peptone)cream tend to reduce pruritus compare to placebo, although the result is not statistically noticeable. Significant difference in reduction of prutitus, the second validation test was not discovered in both groups. Corneometer and life quality tend to be improved with soy cream than placebo, but not statistically effective and both groups did not show any difference in terms of Tewameter measurement. Conclusions : The result of clinical experiment didn't prove that the fermented soybean(Bio-Peptone)cream is more effective in reducing pruritus than placebo, statistically. The clinical use of soybean product for pruritus requires further studies to be verified.

Fast Food Consumption Pattern and Food Habit by Fast Food Intake Frequency of Middle School Students in Wonju Area (원주지역 중학생의 패스트푸드 섭취정도에 따른 패스트푸드 이용태도 및 식습관 비교)

  • Kim, Bok-Ran
    • Journal of Korean Home Economics Education Association
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    • v.21 no.4
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    • pp.19-33
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    • 2009
  • The purpose of this study was to investigate fast food consumption, awareness of fast food and food habit of middle school students in Wonju area according to their intake frequency of fast foods. Subjects were categorized into 3 groups according to intake frequency of fast foods : frequent users($\geq$ 1 times/week, 29.5%) users(2~3 times/month, 50.7%), non-users($\leq$ 1 time/month, 19.8%). As for the purpose of eating fast food, many ate fast food between meals. The most favorite fast food was chicken regardless of intake frequency, followed by pizza, hamburger, the reason being that it tasted good. Regarding if there was any room for improvement, the largest number of the students asked for inexpensive price, irrespective of fast food intake frequency. Compared to users, non-users intake more diverse foods, vegetables, dairy products, fruits, protein foods and seaweed. Users or frequent users of fast food more felt drowsy, cold in the hand and foot, rough skin symptoms than non-users. In conclusion, frequent consumption of fast foods can lead unbalanced diet intakes for middle school students, and those who consumed fast foods frequently showed undesirable food habits in their daily meal.

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Analysis of Crash Load in Crash Impact Test for Fuel Tank of Rotorcraft (항공기용 연료탱크 Phase I 충돌충격시험 충격하중 분석)

  • Kim, Hyun-gi;Kim, Sung Chan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.6
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    • pp.3736-3741
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    • 2015
  • Crash impact test is conducted to verify the crashworthiness of fuel tank. Success of the crash impact test means the improvement of survivability of crews by preventing post-crash fire. But, there is a big risk of failure due to huge external load in the crash impact test. The failure of crash impact test can result in serious delay of a entire rotorcraft development because of the design complement and re-production of the test specimens requiring a long-term preparation. Thus, the numerical simulations of the crash impact test has been required at the early design stage to minimize the possibility of trial-and-error in the real test. Present study conducts on the numerical simulation of phase I crash impact test using SPH supported by crash simulation software, LS-DYNA. Test condition of MIL-DTL-27422 is reflected on analysis and material data is acquired by specimen test of fuel cell material. As a result, the crash load on the skin material, overlap area and metal fitting is estimated to confirm the possibility of acquisition of the design load for the determination of the overlap area and adhesive strength.

Postharvest Handling and Marketing Management for Making High Salability of Sweetpotatoes (상품성 제고를 위한 고구마 수확 후 관리 및 출하기술)

  • Jeong, Byeong-Choon
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2001.06a
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    • pp.51-64
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    • 2001
  • The qualities including taste of sweetpotato stored during the winter which can display in the spring market in Korea are affected by availability of storage for the roots. In order to make high storage availability of sweetpotato, the postharvest handlings should be done thoroughly from the moment of harvest until shipping them to the market. A lot of procedures that must be handled carefully for improving postharvest management are as follows; digging, trimming, gathering, putting in storage containers, carrying them from field to house, curing, storing, washing, drying, selecting marketable roots, packing and shipping to the market, etc.. Sweetpotatoes have a high moisture content, and a relatively thin and delicate skin, and are sensitive to chilling, so careless postharvest handling can lead to both quantitative and qualitative losses which may be extremely high in some circumstances. From now on research has concentrated on the improvement of postharvest conditions to increase yield and lower disease rates. Storage, which makes sweetpotatoes available through out the year, benefits both the producer and the consumer. Seven very important points must be needed in order to get the best quality marketable roots in the storing of sweetpotatos : $\circled1$The storage house must be clean and sanitary, $\circled2$The crop must be harvested before the first frost to avoid low-temperature injury, $\circled3$Particular care must be taken to avoid cutting, bruising, or other injuries of the sweetpotatoes during digging, picking up, grading, placing in containers, and moving to the storage house, $\circled4$Select sound, disease-free roots for storage $\circled5$Sweetpotatoes should be stored in properly stacked containers $\circled6$Cure immediately after harvest, preferably at 32∼33$^{\circ}C$ and 90 to 95 percent relative humidity for 4 to 7 days, After curing the temperature should be reduced to 13$^{\circ}C$ to 16$^{\circ}C$ by ventilating the storage with outside air. $\circled7$Store at 12$^{\circ}C$ to 14$^{\circ}C$ and a relative humidity of 80 to 85 percent. Storage houses should be located on suitable sites and should be tightly constructed and insulated so that temperature and humidity will be uniform. Sweetpotatoes are usually not washed and graded, and lately sometimes washed, graded, waxed, before being shipped to market. Consumer packaging of sweetpotatoes in paper boxes(10-15kg) or film bags is done mainly to aid marketing. The shelf life of washed roots in consumer packs in only 1 to 2 weeks. Weight loss of roots during marketing is much less in perforated film bags than in mesh and paper bags. Perforation of 0.8 to 1kg polyethylene bags with about six 6mm holes is essential ; to lower the internal relative humidity and avoid excessive sprouting, rooting, and dampness. Development and use of better postharvest handling with good storage facilities or marketing methods can minimize sweetpotate losses and has an effect of indirectly increasing productivity and farmer’s income.

Prediction Model of User Physical Activity using Data Characteristics-based Long Short-term Memory Recurrent Neural Networks

  • Kim, Joo-Chang;Chung, Kyungyong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.4
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    • pp.2060-2077
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    • 2019
  • Recently, mobile healthcare services have attracted significant attention because of the emerging development and supply of diverse wearable devices. Smartwatches and health bands are the most common type of mobile-based wearable devices and their market size is increasing considerably. However, simple value comparisons based on accumulated data have revealed certain problems, such as the standardized nature of health management and the lack of personalized health management service models. The convergence of information technology (IT) and biotechnology (BT) has shifted the medical paradigm from continuous health management and disease prevention to the development of a system that can be used to provide ground-based medical services regardless of the user's location. Moreover, the IT-BT convergence has necessitated the development of lifestyle improvement models and services that utilize big data analysis and machine learning to provide mobile healthcare-based personal health management and disease prevention information. Users' health data, which are specific as they change over time, are collected by different means according to the users' lifestyle and surrounding circumstances. In this paper, we propose a prediction model of user physical activity that uses data characteristics-based long short-term memory (DC-LSTM) recurrent neural networks (RNNs). To provide personalized services, the characteristics and surrounding circumstances of data collectable from mobile host devices were considered in the selection of variables for the model. The data characteristics considered were ease of collection, which represents whether or not variables are collectable, and frequency of occurrence, which represents whether or not changes made to input values constitute significant variables in terms of activity. The variables selected for providing personalized services were activity, weather, temperature, mean daily temperature, humidity, UV, fine dust, asthma and lung disease probability index, skin disease probability index, cadence, travel distance, mean heart rate, and sleep hours. The selected variables were classified according to the data characteristics. To predict activity, an LSTM RNN was built that uses the classified variables as input data and learns the dynamic characteristics of time series data. LSTM RNNs resolve the vanishing gradient problem that occurs in existing RNNs. They are classified into three different types according to data characteristics and constructed through connections among the LSTMs. The constructed neural network learns training data and predicts user activity. To evaluate the proposed model, the root mean square error (RMSE) was used in the performance evaluation of the user physical activity prediction method for which an autoregressive integrated moving average (ARIMA) model, a convolutional neural network (CNN), and an RNN were used. The results show that the proposed DC-LSTM RNN method yields an excellent mean RMSE value of 0.616. The proposed method is used for predicting significant activity considering the surrounding circumstances and user status utilizing the existing standardized activity prediction services. It can also be used to predict user physical activity and provide personalized healthcare based on the data collectable from mobile host devices.

An overview of the regulatory effect of vitamin D supplementation on atopic dermatitis (비타민 D의 기능성: 아토피피부염의 조절에 미치는 영향 연구)

  • Sung, Dong Eun
    • Korean Journal of Food Science and Technology
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    • v.53 no.2
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    • pp.139-148
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    • 2021
  • Atopic dermatitis is a chronic, recurrent, inflammatory skin disease that is a well-known allergic disease with severe itching, making daily life difficult. Since the immunomodulatory action of vitamin D has been reported, several researchers have attempted to determine the correlation between vitamin D and atopic dermatitis. In this review, 41 articles meeting the inclusion criteria were selected and reviewed from the articles published to date. Several studies have reported that low vitamin D levels are associated with the onset of atopic dermatitis and severe atopic dermatitis, but the opinions remain conflicting. Similarly, there are conflicting opinions on the improvement effect of oral vitamin D supplementation on atopic dermatitis, but some possibilities have been suggested. To apply vitamin D as a therapeutic agent for atopic dermatitis, a more systematically designed experiment should be conducted, and an appropriate intake dose for an immunomodulatory function should be obtained.

The effect of plasma treatment to improve adhesion strength of parylene-C coated medical grade SUS304 (Parylene-C 코팅된 의료용 SUS304 소재의 결합력 향상을 위한 플라즈마 처리 효과)

  • Kim, Dong-Guk;Song, Tae-Ha;Jeong, Yong-Hoon;Kang, Kwan-Su;Yoon, Deok-kyu;Kim, Min-Uk;Woo, Young-Jae;Seo, Yo-Han;Kim, Kyung-Ah;Roh, Ji-hyoung
    • Journal of Surface Science and Engineering
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    • v.55 no.6
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    • pp.390-397
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    • 2022
  • Parylene-C which was mainly used for industries such as electronics, machinery and semiconductors has recently been in the spotlight in the medical field due to its properties such as corrosion resistance and biocompatibility. In this study we intend to derive a plan to improve the bonding strength of Parylene-C coating with the SUS304 base material for medical use which can be applied to various medical fields such as needles, micro needles and in vitro diagnostic device sensors. Through plasma pretreatment the bonding strength between Parylene-C and metal materials was improved. It was confirmed that the coated surface was hydrophobic by measuring the contact angle and the improvement of the surface roughness of the sample manufactured through CNC machining was confirmed by measuring the surface roughness with SEM. Through the above results, it is thought that it will be effective in increasing usability and reducing pain in patients by minimizing friction when inserting medical devices and in contact with skin. In addition it can be applied to various application fields such as human implantable stents and catheters, and is expected to improve the performance and lifespan of medical parts.

Impacts of stream water quality and fish histopathology by effluents of wastewater treatment plant (하수종말처리장 배출수에 의한 하천 수질 특성 및 어류의 조직병리학적 영향)

  • Kim, Hye-Jin;An, Kwang-Guk
    • Korean Journal of Environmental Biology
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    • v.38 no.4
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    • pp.678-690
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    • 2020
  • In this study, the histological changes of Zacco platypus exposed to discharge from a Wastewater Treatment Plant (WTP), which is a point source, for a long time (2 to 3 years) were compared to the same species at a reference site (Ref.). Overall, tissues displayed various lesions in samples obtained at the point where discharge water from the point source was mixed. In the skin tissue, mucus cells from the epithelial layer expanded to the multilayered epithelium, indicating the immune system was activated. Epithelial cell detachment and proliferation were most prominent in the gills, which may have adversely affected circulation and respiration. Our data suggest immune system collapse was due to stimulation by aquatic substances. Both the fish phase analysis and the water quality analysis demonstrated depreciated conditions at the point source as compared to the reference stream, supporting the histological health evaluation results. These data together suggest a histological approach can also be used to assess water quality, and to an even higher degree when combined with other existing methods. Given the presented evaluation, improvement in the water quality of water discharged from WTP's is required.

Comparison of morphometric traits between small yellow croaker (Larimichthys polyactis) and yellow croaker(L. crocea) (참조기(Larimichthys polyactis)와 부세(L. crocea) 간의 외부계측형질 비교)

  • Park, In-Seok;Oh, Ji Su
    • Korean Journal of Environmental Biology
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    • v.38 no.4
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    • pp.507-517
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    • 2020
  • Several methods including morphometric analysis were used to distinguish small yellow croaker (Larimichthys polyactis) from yellow croaker (Larimichthys crocea), which have very similar external shapes. Morphometric analysis showed four considerable differences (p<0.05) among the total 48 morphometric dimensions, but no differences were seen in the classical dimensions (p>0.05). Rather, significant differences were seen in two truss dimensions: Insertion of dorsal fin base - origin of pectoral fin base and origin of anal fin base - origin of pectoral fin base, and two head part dimension: most anterior extension of the head - above of eye and above of eye - posterior aspect of operculum(p<0.05). However, the yellow croaker had higher values than the small yellow croaker in the other three morphometric dimensions except for the head part dimension of above of eye - posterior aspect of operculum of the four morphometric dimensions (p<0.05). The X-ray photographs indicated that the small yellow croaker (45.1±2.34°) had 8.4% more curved vertebral column than the yellow croaker(38.4±1.82°). A diamond-shaped cranium was found when the skin was peeled off from both fish but the commonly held fact that only the small yellow croaker has a diamond-shaped cranium is not accurate. Our results confirmed that the two fish could be definitely distinguished by their external body shape.