• BMB Reports
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• 제46권4호
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• pp.195-200
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• 2013

To understand the corneal regeneration induced by bevacizumab, we investigated the structure changes of stroma and basement membrane regeneration. A Stick soaked in 0.5 N NaOH onto the mouse cornea and 2.5 mg/ml of bevacizumab was delivered into an alkali-burned cornea (2 ${\mu}l$) by subconjunctival injections at 1 hour and 4 days after injury. At 7 days after injury, basement membrane regeneration was observed by transmission electron microscope. Uneven and thin epithelial basement membrane, light density of hemidesmosomes, and edematous collagen fibril bundles are shown in the alkali-burned cornea. Injured epithelial basement membrane and hemidesmosomes and edematous collagen fibril bundles resulting from alkali-burned mouse cornea was repaired by bevacizumab treatment. This study demonstrates that bevacizumab can play an important role in wound healing in the cornea by accelerating the reestablishment of basement membrane integrity that leads to barriers for scar formation.

• 품질경영학회지
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• 제35권1호
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• pp.1-9
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• 2007

Failure mode and effects analysis (FMEA) is a widely used technique to assess or to improve reliability of products at early stage of design and development. Traditionally, the prioritization of failures for corrective actions is performed by developing a risk priority number (RPN). In practice, due to insufficient evaluation criteria specific to related product and processes, RPN is not properly evaluated. This paper reestablishes an effective methodology for prioritization of failure modes in FMEA procedure. Revised evaluation criteria of RPN are devised and a refined FMEA sheet is Introduced. To verify the proposed methodology, it is applied to RPN evaluation for motors in household appliances.

• 한국임상약학회지
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• 제14권1호
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• pp.24-31
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• 2004

There was clinical study to support the efficacy that the anti-inflammatory and analgesic properties of deoxyribonuclease, bromelain helped to reduce symptoms of inflammation. The current study investigated the effects of deoxyribonuclease, bromelain on local traumatic edema. The author used a drug containing proteolytic and mucolytic enzymes, deoxyribonuclease and bromelain, into 61 patients from 16 to 89 years old. The therapeutic response and tolerance had been excellent, which was permitted to a swift resolution on local traumatic edema and a prompt functional reestablishment. These results demonstrated that the drug was effective in local edema symptoms, pains and improving general condition suffering from trauma. Consequently, the use of the proteolytic and mucolytic enzyme$(Deanase^{(R)})$ require improvement in the rehabilitation of the injured.

• 한국노년학
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• 제31권3호
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• pp.795-811
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• 2011

최근 양육스트레스에 따른 조손가족 조부모의 우울이 높아지면서 조부모의 양육스트레스를 조절하기 위한 관심이 증가하고 있다. 이에 본 연구는 조손가족 조부모의 양육스트레스가 우울에 미치는 영향에 있어 사회적 지지와 대처행동을 조절변수로 설정하여 이들의 조절효과를 파악하고자 했다. 이를 위해 전국 조손가족 중 사회복지서비스를 제공받고 있는 조부모 369명을 대상으로 조사했고, 그 중 334명의 조사결과를 토대로 SPSS 19.0 프로그램을 활용한 위계적 회귀분석과 구조방정식모형을 이용한 다집단분석을 실시하였다. 분석결과는 다음과 같다. 첫째, 양육스트레스, 우울, 사회적 지지, 그리고 대처행동 간에 양육스트레스가 높을수록 우울이 높고, 사회적 지지가 높을수록 양육스트레스가 낮은 관계가 있었다. 또 양육스트레스가 높을수록 대처행동 중 신앙의 의지, 부정적 감정표출, 수동적 회피의 정도가 높은 관계가 있었고, 문제 재정립은 낮은 관계가 있었다. 둘째, 사회적 지지 중 정서적 지지, 정보적 지지, 물질적 지지는 양육스트레스가 우울에 미치는 영향을 조절하는 효과가 있었다. 그러나 평가적 지지는 양육스트레스가 우울에 미치는 영향을 조절하는 데는 효과가 없었다. 셋째, 대처행동 중 신앙의지, 낮은 수동적 회피는 양육스트레스가 우울에 미치는 영향을 조절하는 효과가 있었다. 그러나 문제 재정립은 양육스트레스가 우울에 미치는 영향을 조절하는 데는 효과가 없었다. 한편, 감정표출은 양육스트레스와의 상호작용에서 조절효과를 설명하는데 무의미한 결과가 나왔다. 이를 통해 조손가족 조부모의 양육스트레스와 우울 간 사회적 지지와 대처행동의 조절효과를 높일 수 있는 사회복지실천적 함의를 도출하였다.

• 대한음성학회:학술대회논문집
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• 대한음성학회 1996년도 2월 학술대회지
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• pp.157-172
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• 1996

This study aims to suggest some theoretical methodology for analysis of the prosodic patterns in Korean Read Speech. The engineering effort relevant to the phonetic study has focused to the importance of prosodic phrasing which may play a major role in analyzing the phonetic DB. Before establishing the prosodic phrase as the prosodic unit, we should describe the features of the boundary signal in a target sentence. With this in mind, the general characteristics of Read Speech and the ToBI(tones and Break Indices), which has been currently in vogue with respect to the prosodic labelling system were presented as the first step. The concrete analysis was carried out with the fable 'North Wind and the Sun' Korean version, where about 25 prosodic units were discriminated by perceptual approach for 5 subjects. Establishing various informations which can be used for deciding a boundary position systematically, we can proceed to the next, viz. acoustic analysis of prosodic unit. The most important which we primarily study for improving the naturalness of synthetic speech may be, at first, detecting the boundary signals in the speech file and accordingly reestablishment it within the raw text.

• Fisheries and Aquatic Sciences
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• 제2권2호
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• pp.155-160
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• 1999

Studies on detoxification of Paralytic Shellfish Poison (PSP)-infested oyster, Crassostrea gigas were carried out using available processing resources. Changes of paralytic shellfish toxin components and specific toxicity during canning process were also investigated with high performance liquid chromatography (HPLC). Toxic oysters collected at Hachong in Koje Bay were used for experimental samples. The toxicity of oysters with range of 185-778 ug/100g was reduced below the quarantine limit of 80 ug/100g or not detected level by the mouse bioassay after canning process. The mole $\%$ of toxin components in the shucked oyster was in the order of 25.1 mole $\%$ of gonyautoxin 1, 19.2 mole $\%$ of gonyautoxin 3, 17.2 mole $\%$ of gonyautoxin 4 and 14.6 mole $\%$ of gonyautoxin 2. This sample had tracing amounts of Cl, C2, saxitoxin and neosaxitoxin. In the case of specific toxicity, the major toxins were consisted of gonyautoxin 1-4. The sum of gonyautoxin 1, 2, 3 and 4 was 80% of total toxicity of oyster. Saxitoxin and decarbamoylsaxitoxin were the more thermostable than any other toxin components.

• 복식
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• 제61권9호
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• pp.74-83
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• 2011

In the sense that it performs a function of communication with public, fashion illustration, which visualizes fashion information in an illustrated way, shares similar characteristics with graffiti, which represents the society of its time while having a value as a modern art itself. Therefore, the study aims to seek possibility of graffiti expression of fashion illustration, and to establish theoretical research systems for reestablishment of practical development methods of the graffiti expressions. The concrete contents of this study include followings: First, it examines the methods and characteristics of the graffiti expressions by analyzing the works of graffiti artists in order to understand the concept of graffiti and to find out the theoretical approach to it. Second, it investigates the characteristics of graffiti, and proposes concepts associated with graffiti after analyzing examples of fashion illustration which graffiti expressions are reflected. Third, it draws meanings that the use of graffiti expressions has in fashion illustration. In conclusion, graffiti expressions in fashion illustration are used in brand logos and text, human body deformation and omissions, autonomous expressions of variety of materials, symbolism, amusement, and autonomy as they are characterized by strong colors to express significance.

• 전기전자학회논문지
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• 제10권2호통권19호
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• pp.123-127
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• 2006

인프라가 없는 Ad-hoc 네트워크에서 트래픽 집중은 시스템 성능에 영향을 준다 이에 트래픽을 고르게 분배하여 자원을 효율적으로 소비하는 것이 필요하다. Ad-hoc 네트워크는 경로가 설정되고 통신이 시작되면 링크의 단절이 생기지 않는 한, 경로의 재설정이 이루어지지 않는다. 본 논문에서는 부하증가에 따른 처리능력이 우수한 AODV 라우팅 프로토콜을 수정 개선하여 네트워크의 트래픽 변화에 능동적으로 부하분산을 할 수 있도록 하였다. 수정된 AODV 라우팅 프로토콜은 트래픽이 집중된 노드가 자신의 프래픽 집중을 메시지로 알리고, 이 메시지를 받은 노트들은 대체 노드가 존재하면 경로 변경 후 데이터를 전송한다 수정한 프로토콜의 동작과 성능은 ns2 시뮬레이터를 이용하여 실험 평가하였다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.5-5
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• 2017

Too little and too much water due to climatic events is a significant cause of global food insecurity. Crops are less productive under water-limited conditions and all major crops, with the exception of rice (Oryza sativa), die within a few days of complete submergence. To complement our studies on genes such as SUB1A, (an ERF-VII transcription factor that provides robust submergence tolerance) and AG1 (a TREHALOSE 6-P PHOSPHATASE that promotes establishment of young seedlings underwater), we have retooled INTACT (${\underline{I}}solation$ of ${\underline{N}}uclei$ ${\underline{TA}}gged$ in specific ${\underline{C}}ell$ ${\underline{T}}ypes$) and TRAP (${\underline{T}}ranslating$ ${\underline{R}}ibosome$ ${\underline{A}}ffinity$ ${\underline{P}}urification$) for rice. These technologies enable us to follow dynamics in chromatin, nuclear pre-mRNAs and ribosome-bound mRNAs in meristems and diverse cell types. With these technologies we can better interpret responses to stresses and reestablishment of homeostasis. These include stress acclimation strategies involving changes in metabolism and development, such as dynamics in suberin deposition in sub-epidermal layers of roots that limit water loss under drought and oxygen escape during waterlogging. Our new data uncover dynamic and reversible regulation at multiple levels of gene regulation and provide new insights into processes of stress resilience. Supported by US NSF-PGRP Plasticity (IOS-1238243), Secretome (IOS-1546879) and REU (DBI-146129) grants.

• 건축역사연구
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• 제21권1호
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• pp.47-63
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• 2012

This research aims to demonstrate the sociocultural significance of architectural journals produced in the 1970s during which a fundamental reconsideration of architectural discipline has been made. To this end, we established a method of analysis adapted to the characteristics of architectural journals of that period. In this formulation, the relative autonomy of architectural journal with regard to various actors and institutions involved in its production emerged as a major criterion for the analysis of a journal. From this methodological reflection, we analyzed two French architectural journals, AMC published between 1973 and 1981 and l'Architecture d'Aujourd'hui between 1974 and 1977, which were produced both in close relation with parisian architectural schools (UPA) in the context of reestablishment of architectural education and beginning of architectural research in France after the events of May 1968. If these journals reflected and strengthened the architectural reality and especially the social network of their protagonists, it is equally important to note that they have transformed it into cultural network, and this by the mechanism proper to their preparation and their textual organization.