• 제목/요약/키워드: reduction goal

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Effects of Moutan Cortex on Corticotropin-Releasing Factor, c-Fos and Tyrosine Hydroxylase in Forced Swimming Test (목단피(牧丹皮)가 강제수영부하시험에서 Corticotropin-Releasing Factor, c-Fos 와 Tyrosine Hydroxylase에 미치는 영향)

  • Sung, Young-Suk;Lee, Tae-Hee
    • Herbal Formula Science
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    • v.17 no.1
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    • pp.129-140
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    • 2009
  • Objectives : The goal of this study was to investigate the effect of Moutan Cortex as antidepressant in forced swimming test(FST) model. Methods : The expressions of corticotropin-releasing Factor(CRF), c-Fos and tyrosine hydroxylase(TH) were measured with immunohistochemical method at paraventricular nucleus (PVN), locus coeruleus(LC) and ventral tegmental area(VTA). Results : The duration of immobility in the forced swimming test was significantly decreased in the Moutan Cortex 100 mg/kg treated group in comparison with the control group(p<0.01). CRF and c-Fos expressions at PVN were decreased in the Moutan Cortex 100mg/kg treated group in comparison with the control group. But only the expression of c-Fos was shown the significance(p<0.05). TH expressions at LC and VTA were significantly decreased in the Moutan Cortex 100mg/kg and 400mg/kg treated group in comparison with the control group(p<0.001). Conclusion : According to the results, Moutan Cortex has the antidepressant effect by showing the reduced immobility through the reduction of c-Fos expression at PVN and the reduction of TH expression at LC and VTA.

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SELECTIVE REDUCTION OF ACTIVE METAL CHLORIDES FROM MOLTEN LiCl-KCl USING LITHIUM DRAWDOWN

  • Simpson, Michael F.;Yoo, Tae-Sic;Labrier, Daniel;Lineberry, Michael;Shaltry, Michael;Phongikaroon, Supathorn
    • Nuclear Engineering and Technology
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    • v.44 no.7
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    • pp.767-772
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    • 2012
  • In support of optimizing electrorefining technology for treating spent nuclear fuel, lithium drawdown has been investigated for separating actinides from molten salt electrolyte. Drawdown reaction selectivity is a major issue that requires investigation, since the goal is to remove actinides while leaving the fission products and other components in the salt. A series of lithium drawdown tests with surrogate fission product chlorides was run to obtain selectivity data with non-radioactive salts, develop a predictive model, and draw conclusions about the viability of using this process with actinide-loaded salt. Results of tests with CsCl, $LaCl_3$, $CeCl_3$, and $NdCl_3$ are reported here. Equilibrium was typically achieved in less than 10 hours of contact between lithium metal and molten salt under well-stirred conditions. Maintaining low oxygen and water impurity concentrations (<10 ppm) in the atmosphere was observed to be critical to minimize side reactions and maintain stable salt compositions. An equilibrium model has been formulated and fit to the experimental data. Good fits to the data were achieved. Based on analysis and results obtained to date, it is concluded that clean separation between minor actinides and lanthanides will be difficult to achieve using lithium drawdown.

A Study of Aesthetical Value of Composition principle on Security Guard Martial Arts (경호무도 구성 원리의 미학적 탐색)

  • Jeong, Yeon-Wan;Hong, Eun-Sun
    • Journal of the Society of Disaster Information
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    • v.5 no.2
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    • pp.108-122
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    • 2009
  • Purpose of this research about reduction the scholastic systematic triangular position of the security guard martial art which repeats a development is insufficient with demand of the while society to recognize and for the philosophic value research of security guard martial art composition principle puts out with the one method and from the reporter to search the aesthetics which appears does. In order to attain the goal of the research which sees the literature which relates with an security guard martial art widly, was an investigation and observed the aesthetics from concept and martial art of aesthetics and this the technical free use ability from actual site of the technical find which leads the practice voluntary repetition practice of security guard martial art with character and the body guard aesthetic integral part experience possibly did, there being will be able to acquire an aesthetic inspiration, confirmed. So the security guard martial art follows the composition principle of maximization central attitude and shock point breath control and mental intensive etc. of reinforcement of direction shock of relativity redundancy mental moral culture body agreement characteristic force and relaxation force and is completed and will be able to embody an aesthetic value with aesthetic elements of technical polishing process inside goes about reduction.

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Study in the integrated watershade management for conservation of water resources (II) - Water quality modeling and simulation of Oship stream - (수자원 보전을 위한 유역통합관리 방안에 관한 연구(II) - 오십천 수계의 수질모델링 및 수질 예측 -)

  • 허인량;정의호;권재혁
    • Journal of Environmental Health Sciences
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    • v.28 no.2
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    • pp.61-69
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    • 2002
  • Oship stream is located nearby south eastern coasts. This study was performed to find out waters quality modeling and then to predict water quality of Oship stream. Based on survey data, BOD, T-N, T-P calibration and verification result were in good agreement with measured value within mean coefficient variance(MSE) value, which were 13.9%, 9.0%, 26.5% and 19.5%, 12.0%, 16.5%, respectively. Sectional water quality predictions of the main stream of Oship stream are executed on the basis of the following cases 1) with sewage treatment of Dogye-eup 2) reduction of mine wastewater treatment of 80% in th basin. As a result, BOD, T-P improvement rates at down stream of Oship stream, case 1) were appeared 12.2%, 22.2%, case 2) maximum sulfate ion and conductivity reduction removal rate of Oship stream were 58%, 68%. The main pollution sources of Oship-stream were almost domestic wastewater and mine wastewater discharged from Dogye-eup which located in uppers stream. The large effects will appear after the construction of Dogye sewage water treatment plant which remove the organic matter and nutrients in these sewage water. The waste water from mine can not easily to treat for characteristics of effluence and economic problems. However, to achieve the goal of water quality in Oship-stream water system, treatments of those are necessary.

An Optimal Installation Strategy for Allocating Energy Storage Systems and Probabilistic-Based Distributed Generation in Active Distribution Networks

  • Sattarpour, Tohid;Tousi, Behrouz
    • Transactions on Electrical and Electronic Materials
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    • v.18 no.6
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    • pp.350-358
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    • 2017
  • Recently, owing to increased interest in low-carbon energy supplies, renewable energy sources such as photovoltaics and wind turbines in distribution networks have received considerable attention for generating clean and unlimited energy. The presence of energy storage systems (ESSs) in the promising field of active distribution networks (ADNs) would have direct impact on power system problems such as encountered in probabilistic distributed generation (DG) model studies. Hence, the optimal procedure is offered herein, in which the simultaneous placement of an ESS, photovoltaic-based DG, and wind turbine-based DG in an ADN is taken into account. The main goal of this paper is to maximize the net present value of the loss reduction benefit by considering the price of electricity for each load state. The proposed framework consists of a scenario tree method for covering the existing uncertainties in the distribution network's load demand as well as DG. The collected results verify the considerable effect of concurrent installation of probabilistic DG models and an ESS in defining the optimum site of DG and the ESS and they demonstrate that the optimum operation of an ESS in the ADN is consequently related to the highest value of the loss reduction benefit in long-term planning as well. The results obtained are encouraging.

A Study on the Planning Indicator for Carbon Neutral Green City (탄소중립 녹색도시 구현을 위한 계획지표 설정에 관한 연구)

  • Kim, You-Min;Lee, Joo Hyung
    • KIEAE Journal
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    • v.13 no.2
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    • pp.131-139
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    • 2013
  • The aim of this dissertation is establishing internal indicator list for achieving policy goal of Carbon Neutrality Green City. First of all, it started to construct the basic system of planning indicator based on through comprehension of current studies such as advanced researches, government guidelines and green building certifications. And then it was set up final indicator list through inspecting FGI (Focus Group Interview), Verification of suitability, and Analysis of importance). As a result of this research, the planning indicator divided three steps and there were classified four fields in the top-level; Green Land and Ecology, Green Energy, Green Resource and Transportation, Green Living and Institution. According to the data, it deducted four items (ratio of green land, site plan, heat island and management of climate, base of nature ecology) and twelve index in the field of green land and ecology, three item(energy conservation and self-supporting, energy efficiency, new regeneration energy) and twelve index in the field of green energy and regeneration, five items(water resources utilize and circulation, other resource reduction and circulation, public transportation, green transportation plan) and fifteen index. Totally, Planning Indicators of forty nine were deducted. Therefore, there was the result of importance analysis that the indicators of plan and maintain management as the side of space for carbon neutrality were more appreciated than carbon reduction of individual building.

Sensitivity-based finite element model updating with natural frequencies and zero frequencies for damped beam structures

  • Min, Cheon-Hong;Hong, Sup;Park, Soo-Yong;Park, Dong-Cheon
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.6 no.4
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    • pp.904-921
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    • 2014
  • The main objective of this paper is to propose a new Finite Element (FE) model updating technique for damped beam structures. The present method consists of a FE model updating, a Degree of Freedom (DOF) reduction method and a damping matrix identification method. In order to accomplish the goal of this study, first, a sensitivity-based FE model updating method using the natural frequencies and the zero frequencies is introduced. Second, an Iterated Improved Reduced System (IIRS) technique is employed to reduce the number of DOF of FE model. Third, a damping matrix is estimated using modal damping ratios identified by a curve-fitting method and modified matrices which are obtained through the model updating and the DOF reduction. The proposed FE model updating method is verified using a real cantilever beam attached damping material on one side. The updated result shows that the proposed method can lead to accurate model updating of damped structures.

Effect of Capsaicin on the Formalin-induced Fos-like Immunoreactivity in the Spinal Cord of Rat (Formalin에 의해 흰쥐의 척수에서 유도된 Fos-like Immunoreactivity에 미치는 Capsaicin의 영향)

  • 곽지연;오우택
    • YAKHAK HOEJI
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    • v.43 no.3
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    • pp.404-410
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    • 1999
  • Administration of capsaicin produces acute pain and subsequent long-lasting antinociception. The antinociceptive action site of capsaicin is primarily small afferent nerve fibers. However, the effect of capsaicin on the neural activity of dorsal horn neurons are not well understood. The goal of the present experiment was to study the action of capsaicin on activity of dorsal horn neurons using c-fos immunoreactivity in the spinal cord. Intradermal injection of formalin in the hindpaw produced inflammation in the foot pad and increased the number of cells exhibiting Fos-like immunoreactivity (FLI) in the dorsal horn of the spinal cord, suggesting the hyperalgesia because of the apparent inflammation. Intradermal injection of capsaicin prior to formalin injection significantly reduced the number of cells exhibiting FLI induced by formalin and increased the paw-withdrawal latency, suggesting the hypoalgesic effect of capsaicin. Coadministeration with capsaicin of capsazepine and ruthenium red, antagonists of capsaicin receptor reversed the reduction of formalin-induced FLI by capsaicin. he antagonists also partially antagonized the antinociceptive effect of capsaicin in the paw-withdrawal test. These results further suggest that capsaicin reduces prsponses of dorsal horn neurons to the inflammatory nociceptive stimuli in the periphery. Thus, the reduction of FLI subserves the neural mechanisms underlying analgesia produced by capsaicin.

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Probabilistic penalized principal component analysis

  • Park, Chongsun;Wang, Morgan C.;Mo, Eun Bi
    • Communications for Statistical Applications and Methods
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    • v.24 no.2
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    • pp.143-154
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    • 2017
  • A variable selection method based on probabilistic principal component analysis (PCA) using penalized likelihood method is proposed. The proposed method is a two-step variable reduction method. The first step is based on the probabilistic principal component idea to identify principle components. The penalty function is used to identify important variables in each component. We then build a model on the original data space instead of building on the rotated data space through latent variables (principal components) because the proposed method achieves the goal of dimension reduction through identifying important observed variables. Consequently, the proposed method is of more practical use. The proposed estimators perform as the oracle procedure and are root-n consistent with a proper choice of regularization parameters. The proposed method can be successfully applied to high-dimensional PCA problems with a relatively large portion of irrelevant variables included in the data set. It is straightforward to extend our likelihood method in handling problems with missing observations using EM algorithms. Further, it could be effectively applied in cases where some data vectors exhibit one or more missing values at random.

Impact of Balance between Productivities on Repetitive Construction Projects

  • Shim, Euysup;Yoo, Wi Sung
    • Journal of the Korea Institute of Building Construction
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    • v.13 no.4
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    • pp.360-371
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    • 2013
  • Fast delivery of construction projects provides more value to project owners. Batch production, which is production not in single pieces, but in batches, is a common approach in repetitive construction projects such as multi-unit residential building construction projects. In batch production, the use of a small batch size allows the early start of subsequent activities, and thus can lead to early completion of projects. In addition to batch size, balance between productivities in construction activities can affect project duration. However, the impact of the balance between productivities with regard to their order on project duration has not been studied. The main goal of this study is to test a hypothesis, which is that the order of construction activities' unbalanced productivities affects the amount of time reduction that can be achieved by using a small batch size. A computer-based simulation model was developed, and five different cases were simulated to test the hypothesis. The conclusion of the simulation result is that the order of productivities does not affect the time reduction achieved by using a small batch size. It is expected that the findings of this study can help general contractors make decisions in terms of batch size.