• Journal of the Korea institute for structural maintenance and inspection
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• v.8 no.3
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• pp.251-261
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• 2004

Recently, the corrosion and aging of bridge structures are of great concern impractical The uncertainties of the corroded reinforced bars in concrete influence not only the safety of the bridge structures, but also the flexural strength of reinforced concrete members. This paper considers these uncertainties by providing a reliability-based framework and show that the identification of the optimum maintenance scenario is a straightforward process. This is achieved by using a computer pro망am for Life Cycle Cost Analysis of Deteriorating Structures (LCCADS). This program can consider the effects of various types of actions on the reliability index profile of a deteriorating structures.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.50 no.9
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• pp.663-668
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• 2022

Since the early 2000s, the United States has applied TLCSM to reduce life cycle costs while maintaining the weapons system's combat readiness. With the application of TLCSM, the ILS concept centered on the acquisition stage shifted to IPS, a concept that manages life cycle costs throughout the entire life cycle. In addition, LSAR for developing ILS has switched to LPD for developing IPS. In this study, LSAR in Korea and LPD in the United States were compared and analyzed, and policies necessary for the introduction of LPD in Korea were proposed.

• The Journal of Society for e-Business Studies
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• v.3 no.1
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• pp.43-67
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• 1998

Logistics is by no means a new subject area. The concept of logistics goes way become more complex as technology advances, and logistics requirements have increased accordingly. In 1964, when ILS philosophy formally came into being, ILS was defined in general terms and did not describe what actions an ILS program should accomplish. ILS philosophy have been developed from 1964 through 1980. In 1982, United States Department of Defense formulated a new concept, CALS. CALS is the strategy that the US defense development to management the transition to integration and automated interchange in defense system engineering, manufacturing, and logistic support. Its goal is to use the inherent features of digitized data to revolutionize the function of data -gathering, data storage and data - transfer techologies associared with the development of defense systems. The Result will be systems that are cheaper, more reliable, and easier to maintain. To define CALS's character, the purpose of this papers compare two concepts - CALS and ILS. The elements of CALS consist of standads and EDI. The elements of ILS include LCC(Life Cycle Cost), LSA(Logistics Support Analysis), LSAR(Logistics Support Analysis Rcord), Aquisition Cycle.

• Journal of Korean Society of Steel Construction
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• v.20 no.2
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• pp.259-268
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• 2008

This paper proposes a method to establish an optical lifetime maintenance strategy for deteriorating bridges in consideration of life-cycle performance and cost. A program is developed based on the proposed method, which can generate optimum maintenance scenarios not only at the individual member level but also at the system level of the bridge. By applying the developed program is studied through the comparative analysis of maintenance strategies generated at each level. According to the results of comparison between maintenance strategies of the member-level analysis and system-level analysis. It is expected that the establishment of a maintenance strategy through the bridge system-level analysis considering target, members reflects practical and reasonable results.

• Land and Housing Review
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• v.3 no.4
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• pp.399-406
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• 2012

One-third of total energy and 50% of $CO_2$ emissions arise from construction phase. Because of this global amount of energy consumption and $CO_2$ emission, we must do our best to solve this problem. But our existing ways of meeting this problem has focused on the energy consumption saving of the construction and dwelling stage. On the other hand, we has been treated too lightly for handling the $CO_2$ emissions problem during the maintenance management and the demolition process so far,. In this paper, we quantitatively predicted and evaluated the environmental load in each construction step during all life cycle. And, we developed the environmental load assessment program for each construction step. And we proposed the reliable decision support model for objective and reliable environmental load assessment and reduction. This result must help the development of construction technology and low carbon & green growth.

• Journal of the Korean Home Economics Association
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• v.49 no.2
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• pp.51-62
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• 2011

The purpose of this study was to develop field programs to activate family volunteering and thereby promote healthy family life. The programs were based on a review of family ecological theories of family volunteering activities. A focus group interview was conducted about satisfaction of the program with five volunteers who were experiencing the same family life cycle. The results of study showed that growing sprouts, which are environmentally friendly activities in family, and family volunteer activities lead to family leisure, table, community sharing cultures and cooperation culture between the family and the community. These effects can ultimately contribute to the creation of a healthy family culture.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1996.11a
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• pp.567-571
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• 1996

The objective of STEP is to provide neutral mechanism capable of describing product data through the life cycle of a product, independent form any particular systems. This paper describes an STEP application program that can display the three-dimensional shape based on b-spline surface and the data which defines configuration of the product. The developed program is based on the STEP part 203 “Configuration controlled design”.

• Molecules and Cells
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• v.38 no.1
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• pp.40-50
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• 2015

In the interaction between plants and pathogens, carbon (C) resources provide energy and C skeletons to maintain, among many functions, the plant immune system. However, variations in C availability on pathogen associated molecular pattern (PAMP) triggered immunity (PTI) have not been systematically examined. Here, three types of starch mutants with enhanced susceptibility to Pseudomonas syringae pv. tomato DC3000 hrcC were examined for PTI. In a dark period-dependent manner, the mutants showed compromised induction of a PTI marker, and callose accumulation in response to the bacterial PAMP flagellin, flg22. In combination with weakened PTI responses in wild type by inhibition of the TCA cycle, the experiments determined the necessity of C-derived energy in establishing PTI. Global gene expression analyses identified flg22 responsive genes displaying C supply-dependent patterns. Nutrient recycling-related genes were regulated similarly by C-limitation and flg22, indicating re-arrangements of expression programs to redirect resources that establish or strengthen PTI. Ethylene and NAC transcription factors appear to play roles in these processes. Under C-limitation, PTI appears compromised based on suppression of genes required for continued biosynthetic capacity and defenses through flg22. Our results provide a foundation for the intuitive perception of the interplay between plant nutrition status and pathogen defense.

• Journal of National Security and Military Science
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• s.2
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• pp.261-283
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• 2004

To build up the military strength based on information oriented armed forces, the Korean ministry of national defense (MND) promotes the defense CALS (Continuous Acquisition and Life cycle Support) initiative for the reductions of acquisition times, improvements of system qualities, and reductions of costs. These defense CALS activities are the major component of the underlying mid and long term defense digitization program and the ultimate goal of program is to bring a quick victory by providing real-time battlefield intelligence and the economical operations of the military. The concept of defense CALS is to automate the acquisition and disposition of defense systems throughout their life cycle. For implementing defense CALS, the technology for exchange and sharing CALS standard data that is created once and used many times should be considered. In order to develop an efficient CALS information exchange and sharing system, it is required to integrate distributed and heterogeneous data sources and provide systematic search tools for those data. In this study, we developed a content based search engine technology which is essential for the construction of integrated data environments. The developed technology provides the environment of sharing the CALS standard data such as SGML(Standard Generalized Markup Language) and STEP(Standard for The Exchange of Product model data). Utilizing this technology, users can find and access distributed and heterogeneous data sources without knowing its actual location.

• BMB Reports
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• v.57 no.1
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• pp.30-39
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• 2024

Directed evolution (DE) of desired locus by targeted random mutagenesis (TRM) tools is a powerful approach for generating genetic variations with novel or improved functions, particularly in complex genomes. TRM-based DE involves developing a mutant library of targeted DNA sequences and screening the variants for the desired properties. However, DE methods have for a long time been confined to bacteria and yeasts. Lately, CRISPR/Cas and DNA deaminase-based tools that circumvent enduring barriers such as longer life cycle, small library sizes, and low mutation rates have been developed to facilitate DE in native genetic environments of multicellular organisms. Notably, deaminase-based base editing-TRM (BE-TRM) tools have greatly expanded the scope and efficiency of DE schemes by enabling base substitutions and randomization of targeted DNA sequences. BE-TRM tools provide a robust platform for the continuous molecular evolution of desired proteins, metabolic pathway engineering, creation of a mutant library of desired locus to evolve novel functions, and other applications, such as predicting mutants conferring antibiotic resistance. This review provides timely updates on the recent advances in BE-TRM tools for DE, their applications in biology, and future directions for further improvements.