• Journal of the Korean Society for Precision Engineering
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• v.9 no.1
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• pp.82-95
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• 1992

There is the high interest for sensing of tool wear with the aim of controlling machine tools productivity from the point of view of qualitity. Difficulties in this measurement are also known. This study is on the development of measurement setup for crater wear by CCD image inturning. In this study, the crater wear measurement system consists of the He-Ne gas laser, diffraction grating. CCD camera, noise filter, slit, microcomputer, diverging lens, converging lens and so on. He-Ne laser beam passes through a diverging lens and a diffraction grating is positioned properly. A converging lens focuses so that the interference fringes can be obtained on the crater wear. Performance test revealed that the developed image technique provides precise, absolute tool-wear quantification and reduces human measurement errors. The results obtained are as follows 1. The digitizing of one image requires less than 2ses. 2. It can give detailed information on crater wear with limited times and errors 3. All parameters required by specification are easily obtained for several points of the cutting edge.

• Korean Chemical Engineering Research
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• v.55 no.1
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• pp.80-85
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• 2017

Recently, microalgae which can produce high-value products have attracted increasing attention for biological conversion of $CO_2$. However, low photosynthetic efficiency and productivity have limited the practical use of microalgae. Thus, we developed microdroplet photobioreactor for the analysis of photoautotrophic growth of model alga, Chlamydomonas reinhardtii. $CO_2$ transfer rate was increased by integrating micropillar arrays and adjusting height of microchamber. These results were identified by change of cell growth rate and fluorescence intensity. Lastly, the photoautotrophic growth kinetics of C. reinhardtii in microdroplet photobioreactor were investigated under different $CO_2$ concentrations and light intensities for 96 hours. As a result, microdroplet photobioreactor was efficient platform for isolation and rapid evaluation of microalgal strains which have enhanced productivity of high-value products and growth performance.

• KSBB Journal
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• v.20 no.6
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• pp.447-452
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• 2005

The hydrogen production using immobilized cellsl was conducted using fruit wastewaters at various culture conditions. Three kinds of fruit wastewaters, melon, watermelon and pear were used. Sodium alginate was used as immobilization material. Among them, concentration of reducing sugar which was one of the main components in fruit was the highest at watermelon wastewater, and also hydrogen production was the highest as 2319.2 mL/L in it. Although hydrogen production was not much changed according to sodium alginate concentration, its production was the most at 3%(w/v). As bead size as small, hydrogen production was higher. With inspection of interior, it confirmed that the cell grew well in bead. But the addition of amino acids using as agent for metabolite production had almost no affected on hydrogen productivity. The effective range of $FeSO_4$ addition on hydrogen production were up to 1.2 g/L, and above the concentration, it inhibited the productivity. Organic acids produced during watermelon fermentation were mainly lactic acid, butyric acid, abd acetic acid; and a little of propionic acid.

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.145-148
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• 2003

High concentration of glutathione(GSH) has been found in some species of yeast, of which Saccharomyces cerevisiae is used for commercial fermentative production. In this study, we have investigated the optimal conditions of production which could increase the GSH productivity and used it to maximize the production of GSH in fed-batch culture of Sacchromyces cerevisiae. Fermentation process have been also real time monitored by a 2-dimensional fluorescence sensor.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.66 no.2
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• pp.468-473
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• 2017

This paper presents an in-process measurement system for shaft radius measurement during grinding process. This system does not require to stop the grinding process, which can enhance productivity and quality. In order to measure the radius, the system employs an eddy current sensor that can measure without any contact with the shaft. This type of sensor is very appropriate because it is insensitive to interference such as cutting fluid, coolant, contact pressure, and wear. For data analysis, the measurement system is modeled as a linearized discrete form where the states with noise are estimated by an extended Kalman filter. This system has been validated through simulations and experiments.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.3
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• pp.711-718
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• 2003

Wanpae-tang is suggested to have antitumor activity on lung cancer. This study was performed to investigate antitumor, immune response, and apoptotic effects by Wanpae-tang in the cancer cell lines and C57BL/6 mice. Experimental studies were progressed through the anticancer activities such as, survival time, cell cytotoxicity, natural killer cell activity, productivity of interleukins and apoptotio effects. The results were summarized as follows: 1. Median survival time of Wanpae-tang treated group was prolonged to 4.1%, as compared with control group, but was not significant. 2. On the MTT assay, half-maximal inhibitory concentration(IC50) of Wanpae-tang was 15.00 ㎎/㎖ in HeLa cell, and 4.158 ㎎/㎖ in HRT-18 cell. 3. Natural killer cell activity in Wanpae-tang treated group was decreased in case of 100:1 and 10:1 effect cell/target cell ratio. 4. Production of interleukin-2, 4, 12 in Wanpae-tang treated group were significantly increased. 5. On the studies of Wanpae-tang induced apoptosis, a DNA fragmentation patterns were not appeared.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.31 no.1
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• pp.45-55
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• 1998

Phytoplankton community and primary productivity have been investigated in a fall season in the southern coastal waters of the last Sea, Korea. A strong thermocline formed at the 20\~60\;m$ layer and a cold water mass also existed in the bottom around Yong-il Bay. The offshore of the surveyed area was likely to be influenced by relatively warmer water, whereas the inshore represented Higher primary productivity with lower water temperature and lower salinity. A total of 133 species of phytoplankton occurred, representing 107 spp. of diatom, 23 spp. of dinoflagellate 3 spp. of silicoflagellate. Skeletonema costatum and Asterionellepsis glacialis were most predominant with more than $30\%$ dominance ratio, while Leptocylindrus danicus was also dominant at all transect lines. Standing crops of phytoplankton ranged from $2.7{\times}10^3\;to\;141.6{\times}10^3\;cell^{\ell-1}$. Chlorophyll a concentration varied with stations and layers, but the $30\~50$ m layer showed maximun with about $1.18{\mu}g{\ell}^{-1}$ rather than at the surface layer. It is believed that the maximun in standing crops and chlorophyll of phytoplankton formed at the $20\~50$ m layer above the thermocline during the survey. Phytoplankton primary productivity ranged from 0.32 to 3.04 mgC $m^{-3}\;hr^{-1}$, showing higher at the inshore than at the offshore. The range of integrated primary productivity was $263.3\~1085.5 mgC\;m^{-2}\;day^{-1}$ for the euphotic layer. Photosysthesis rates varied with the range from 0.76 to 8.04 mgC mgChl $\alpha^{-1}\;hr^{-1}$. Phytoplankton photosynthesis at the inshore was saturated at lower irradiance ($15\~35\%$ of surface) and showed higher efficiency, Thus, it revealed that the phytoplankton community probably adapted to the middle of euphotic layer because the depth of mixing layer became thinner due to the formation of thermocline.

• The Journal of Health Technology Assessment
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• v.6 no.2
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• pp.123-132
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• 2018

Objectives: Maternal morbidity and mortality are important healthcare issues. However there have been few studies on cost of illness (COI) from maternal disorders. This study aimed to estimate the COI due to maternal disorders in Korea. Methods: By reviewing previous studies and consulting expert we determined the scope of maternal disorders. We operationally defined maternal disorders as maternal hemorrhage, maternal sepsis, hypertensive disorders of pregnancy, obstructed labor, and abortion for maternal disorders. The reference period of this study is the year 2015. Main source of data were the National Health Insurance Service claims data, cause of death statistics from the Korea National Statistical Office, and the Korea Health Panel study. We classified the total costs into direct and indirect costs. The direct costs cover healthcare costs and non-healthcare costs. The indirect costs consist of productivity losses due to morbidity and premature death. Results: The cost of maternal disorders in 2015 was 229.7 billion won. The direct and indirect costs of maternal disorders were 165.2 billion won and 64.5 billion won respectively. The largest cost item for maternal disorders was healthcare cost (138.3 billion won, 60.2%). By age groups, the COI in 30-39 years old women were the highest (165.1 billion won, 71.9%). Abortion was the disorder with the highest COI among maternal disorders (71.9 billion won, 31.3%). Conclusion: The COI due to maternal disorders in Korea is quite substantial. Economic burden of maternal disorder increased when being compared with the year 2012 data despite the continued low birth rate in Korea. Therefore, it is necessary to continuously monitor the social costs of the maternal disorders in Korea.

• The Journal of Internal Korean Medicine
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• v.24 no.2
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• pp.315-328
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• 2003

This study was performed to investigate the effect of Bunsimgieum on antitumor effect after sarcoma-180 cells transplantation into peritoneal cavity or left groin and immune responses on the depressed immunity induced by methotrexate in mice. The Bunsimgieum extract of 10mg/kg was orally administered 14 days for antitumor effects and 21 days for immune responses. 50% inhibitory concentration($IC_{50}$) of SUN-1, SUN-C4, and SUN-396 cancer cell, mean sunvival days and body weight of tumor bearing mice, and growth of tumor mass for antitumor effect; delayed type hypersentivity, hemagglutinin titer, hemolysis titer, rosette forming cells, natured killer cell activity, lymphocyte transformation, productivity of interleukin-2, and phagocytic activity for their immune responses were measured in ICR mice. Significance in antitumor effect is noted in the enlongation of mean life days and inhibition of tumor growth(p<0.01, respectively). Significance of immune responses is also noted in hemolysis titer, lymphocyte transfumotion, IL-2 productivity, phagocytic activity, and natural killer cell activity at E/T ratio 100:1(p<0.01, respectively). Significant in rosette cell formation was seen at dosage of 20mg/kg(p<0.01). However, Difference of body weight as antitumor effect, delayed type hypersensitivity, and hemagglutinin titer were not shown significantly. According to the above results, it could be suggested that Bunsimgieum has prominent antitumor and immunity enhancing effect.

• Journal of The Korean Society of Grassland and Forage Science
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• v.12 no.3
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• pp.185-192
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• 1992

This experiment was conducted to compare the productivity of five silage corn varieties. Corn varieties were Pioneer 3144(P 3144), 3160(P 3160), 3282(P 3282), 3352(P 3352) and Suweon 19(S 19) and were seeded on May 2 and harvested on August 15. Ratios of stalk, leaf and ear, chemical composition and yields of nutrients were investigated in respective corn part. Experimental design was accepted by Latin square arrangement with five replicates and each plot had twenty two plants. The results obtained were as follows: 1. Crude portein, crude ash and nitrogen free extract(NFE) contents of whole plant ranged from 6.32 to 7.18%, 5.16 to 7.43% and 52.62 to 57.90%, respectively, and there were no significant(P>.Ol) differences between varieties. Crude protein and NFE content were the highest in ear between corn parts. 2. Crude fiber conent of whole plant ranged from 18.98 % to 24.01 %, and was the highest in suweon 19 and the lowest in P 3352(P<.01). Crude fiber content was the highest in stem and the lowest in ear, However, crude fat content(2.03-3.66 %) vice versa. 3. Yields of organic matter, crude protein, crude fat, NFE and TDN per 10a were the greatest(P< .01) in P 3282, however crude fiber yield was the highest(P<.Ol) in P 3352. 4. Ratios of different part to total dry matter yield ranged from 12.7 %(P 3352) to 17.8 %(P 3160) for leaf, 44.5(P 3352) to 66.9 %(P 3160) for stem and husks, and 16.9 %(P 3282) to 42.8 %(P 3352) for ear, and there were significant differences between corn varieties(P<.Ol). Consequently, P 3352 has the greatest nutrient yields, particularly by ear, and P 3282 has a great nutrient yield by stem. This result suggested that could be appear a better character of silage corn by hybridization of this two corn varieties.