• Title/Summary/Keyword: primary-grade

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Intrinsic Tumour Factors Affecting Recurrence in Non Muscle Invasive Bladder Cancer: a Hospital Based Study from India

  • Mehta, Nisarg;Rathore, Ranjeet Singh;Pillai, Biju S;Sam, Mohan P;Moorthy, Krishna
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2675-2677
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    • 2015
  • Background: Depending on various pathological factors, non muscle invasive bladder cancer (NMIBC) shows varying degrees of recurrence. The aim of this study was to determine the incidence of recurrence of NMIBS in our centre, study the influence of intrinsic tumour characteristics like grade, stage, size and number, and compare our results with data in the published literature. Materials and Methods: A hospital based retrospective study was conducted on patients who underwent treatment for NMIBC from 2011 to 2014. The factors studied were number, size, grade, stage and site for correlation with recurrence. Statistical analysis was performed using Medcalc version 12, using Pearson's Chi square test to ascertain associations between variables. Results: A total of 73 patients with NMIBC were studied of which 48 (65.8%) had low grade and 25 (34.2%) had high grade tumours. Some 38 patients (52.1%) had Ta tumours, 34 (46.6%) had T1 and one had CIS. Mean follow up was 34.3 months. Recurrence rates were found to be 33.3% in low grade and 52.0% in high grade tumours. The overall recurrence rate in our centre was 39.7%. Significant correlations were seen between stage and recurrence, with a rate of 15% for Ta and 63.3% for T1 tumours. Fourteen out of 21 bladder cancers (66.6%) with multiple tumours demonstrated recurrence (p=0.006). Grade, size and site had no influence. Conclusions: In our study, recurrence of NMIBC was found to be directly proportional to stage and number of primary tumours, but not grade, size and site. The incidence of recurrence of NMIBC both stage wise and grade wise in our centre was also low compared to the data in the published literature.

Quality Characteristics by Grade of Commercial Frozen Surimi (냉동수리미의 등급에 따른 품질특성)

  • Ahn, Byeong-Soo;Kim, Byeong-Gyun;Jeon, Eun-Bi;Lee, In-Seok;Oh, Kwang-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.52 no.6
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    • pp.555-561
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    • 2019
  • We examined the quality characteristics of four kinds of Alaska pollack Theragra chalcogramma surimi (APS), five kinds of golden threadfin bream Nemipterus virgatus surimi (GTS), and two kinds of giant squid Ommastrephes bartrami surimi (GSS) used in Korea. The volatile basic nitrogen contents of APS, GTS, and GSS increased with decreasing grade to 6.8-9.8, 5.5-8.3, and 143.5-177.7 mg/100 g, respectively. The Ca2+-ATPase activities of APS and GTS decreased with decreasing grade to 0.63-0.83 and 0.60-0.80 pi μmole/min/mg, respectively. The Ca2+-ATPase activity of RA-grade GSS was 0.82-0.91 pi μmole/min/mg. The whiteness values of APS, GTS, and GSS heat-induced gels were 54.0-71.4, 53.9-71.0, and 52.2-70.3, respectively, and that of both APS and GTS decreased with decreasing grade. The gel strengths of APS and GTS heat-induced gels were 412.3-769.4 and 280.2-456.5 g·cm, respectively, and decreased with decreasing grade. The total amino acid contents of SA-grade APS, SSA-grade GTS, and RA-grade GSS were 17,328.1, 17,965.0, and 14,846.8 mg/100 g, respectively, and the major amino acids were glutamic acid, aspartic acid, arginine, leucine, lysine, proline, alanine, and phenylalanine. The primary minerals were sodium (136.6-164.9 mg/100 g), potassium (45.7-160.4 mg/100 g), phosphorus (35.0-73.5 mg/100 g), sulfur (22.8-56.4 mg/100 g), and calcium (18.0-203.4 mg/100 g).

A case of Primary Hard Palate Adenocarcinoma Metastasizing to Cervical Lymph Nodes 9 Years after Resection of Primary Lesion (원발병소의 외과적 절제 9년 후 경부 림프절에 전이된 경구개 선암종 1예)

  • Lee Hyung-Seok;Jeon Sung-Ha;Hong Dong-Kyun;Cho Seok-Hyun;Tae Kyung
    • Korean Journal of Head & Neck Oncology
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    • v.20 no.1
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    • pp.44-48
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    • 2004
  • Primary malignancies of hard palate are rare, espicially adenocarcinoma of minor salivary gland in hard palate. The clinical stage of the tumor and its histologic grade at the time of treatment were significant predictors of survival. A 33-year-old woman was diagnosed with stage II, polymorphous low-grade adenocarcinoma of the hard palate and treated with surgery. We thougt that she would have excellent prognosis. After that, there was no definite evidence of recurrence during 3 months. Since then, the patient herself decided to discontunue follow-up. 9 years after that she came to the hospital due to both submandibular mass without any sign of local recurrence. CT scan and biopsy of the mass revealed multiple cervical metastatic adenocarcinoma without distant metastasis and the histologic findings were similar to that of the primary hard palate adenocarcinoma. So, we present this case with the review of literature.

Utilization Plan of primary 3-4 grade mathematics textbooks for 'Flipped Classroom' (수학과 '거꾸로 교실' 수업을 위한 교과서 활용 방안 탐색 - 초등학교 3-4학년 군을 중심으로)

  • Kim, Soo Cheol
    • Education of Primary School Mathematics
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    • v.17 no.3
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    • pp.265-276
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    • 2014
  • In this study, we aim to search the utilization plan of primary 3-4 mathematics textbooks for 'Flipped Classroom' practice. In the flipped classroom, students are required to manipulate more rigorous concepts, deal with realistic problems and various activities, and discussions. Researcher analyzed the new mathematics textbooks of primary 3-4 grade that is applied 2014. The criteria of analysis was made of the instructional model for 'Flipped Classroom' that was set up by previous researcher. To practice the flipped classroom, teachers need to design their classes carefully for using selectively many materials of the textbooks to make students participate discussion in the classroom actively and to consider their interests and levels.

The Status and Attitudes on Drug Abuse in Primary School Students (초등학교 학생의 약물남용에 대한 실태와 태도)

  • Park, In-Hyae;Cho, In-Sook;Ryu, Hyun-Sook
    • Journal of the Korean Society of School Health
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    • v.16 no.1
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    • pp.121-133
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    • 2003
  • The purpose of this study was to find out the status of and attitudes on drug abuse in primary school students, to provide basic data for preventing the youth from their drug abuse and contributing to improve their health. 36.0% of the students had an experience of the education to prevent from drug abuse, the students wanted to have an education on drug abuse in primary school, 71% of the subjects preferred to school nurses as the education about drug abuse, and 2.9% of the students show their intention to use drug when their friends recommend to take drug. For the experience of drinking, there was a significant difference to the degree of satisfaction at their school($x^2$=23.29, p=.001), their association with father's smoking ($x^2$=13.16, p=.001), and mother's ($x^2$=5.60, p=.018) smoking. The experience of drinking showed no significant differences according to the grade and the experience of prevention education on drug abuse. Attitudes on drug abuse according to the general characteristics showed significant differences according to the grade (t=4.10, p=.007), the degree of satisfaction at the school(t=8.86, p=.000), their association with any father's drinking(t=3.18, p=.002) and mother's(t=5.23, p=.000), father's smoking(t=3.21, p=.001) and mother's(t=31.87, p=.000), the state of drug use during the pain(t=7.18, p=.000).

Stereotactic body radiation therapy for liver oligo-recurrence and oligo-progression from various tumors

  • Cha, Yu Jin;Kim, Mi-Sook;Jang, Won-Il;Seo, Young Seok;Cho, Chul Koo;Yoo, Hyung Jun;Paik, Eun Kyung
    • Radiation Oncology Journal
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    • v.35 no.2
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    • pp.172-179
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    • 2017
  • Purpose: To evaluate the outcomes of stereotactic body radiation therapy (SBRT) for patients with liver oligo-recurrence and oligo-progression from various primary tumors. Materials and Methods: Between 2002 and 2013, 72 patients with liver oligo-recurrence (oligo-metastasis with a controlled primary tumor) and oligo-progression (contradictory progression of a few sites of disease despite an overall tumor burden response to therapy) underwent SBRT. Of these, 9 and 8 patients with uncontrollable distant metastases and patients immediate loss to follow-up, respectively, were excluded. The total planning target volume was used to select the SBRT dose (median, 48 Gy; range, 30 to 60 Gy, 3-4 fractions). Toxicity was evaluated using the Common Toxicity Criteria for Adverse Events v4.0. Results: We evaluated 55 patients (77 lesions) treated with SBRT for liver metastases. All patients had controlled primary lesions, and 28 patients had stable lesions at another site (oligo-progression). The most common primary site was the colon (36 patients), followed by the stomach (6 patients) and other sites (13 patients). The 2-year local control and progression-free survival rates were 68% and 22%, respectively. The 2- and 5-year overall survival rates were 56% and 20%, respectively. The most common adverse events were grade 1-2 fatigue, nausea, and vomiting; no grade ${\geq}3$ toxicities were observed. Univariate analysis revealed that oligo-progression associated with poor survival. Conclusion: SBRT for liver oligo-recurrence and oligo-progression appears safe, with similar local control rates. For liver oligo-progression, criteria are needed to select patients in whom improved overall survival can be expected through SBRT.

The Effects of a Staged Smoking Prevention Program for Primary School Children (초등학생을 위한 단계별 흡연예방 프로그램의 효과)

  • Kim, Jae-Hee;Lee, Yu-Jeong;Kang, Seong-Mi;Oh, Yu-Mi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.8
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    • pp.5131-5139
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    • 2014
  • The subjects of this study were 415 children in the first to third grade selected from 4 primary schools. Among them, 212 children belong to the experimental group, and 203 children were in the control group. The program was provided respectively to first, third and fifth grade children for 2, 4 and 6 teaching-hours from 2013.1.1 to 2013.12.19. To measure the effects of the program, the knowledge and attitudes on/toward smoking, self-concept were used as the research tools. Before and after program-implementation, there were significant differences in knowledge of smoking, but no differences in attitudes and self-concept. A smoking prevention program for primary school children should be applied step-by-step in conjunction with the regular education curriculum. In addition, the program should aim for long-term effects rather than short-term effects.

A study en the preference and food behavior of the children in primary school foodservice II (아동의 기호도와 식습관에 관한 조사연구 ( II ))

  • Lee, Won-Myo;Bang, Hyeong-Ae
    • Journal of the Korean Dietetic Association
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    • v.2 no.1
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    • pp.69-80
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    • 1996
  • This study was performed to investigate the food preference trends of the children according to age increase and change of the times. The subjects were 1,450 children who are fifth grade of primary school and 2,000 juveniles who are senior high school in 1993. This survey data were compared with the Food preference study of the primary school aged children in 1987.' The results of this study can be summarized as follows 1. State of the general taste The subject had a high preferences to bulgogi(roast beef), panbroiled cuttlefish, steamed egg, fried sausage and donuts among the all sorts of 165 principal and subsidiary foods. But, fried beef liver, pancake, sweet potato with syrup, spinach soup and boiled rice with red bean didn't suit for their taste. Compared with survey data done in 1987, in present study significantly increased preferences to steamed food, pan frying and parboiled vegetables were shown. Particularly, food preference was changed with the cooking methods rather than materials. 2. Differences of the preference according to change of the times In present study, except the rice cakes preferences to all sorts of foods were improved and markedly increased preferences to steamed food, parboiled vegetables and mixed with seasonings were observed. Compared with 87's study deviation of the preference to cooking materials was decreased considerably. Preferences to salty tasted foods as like as stew and salted food were low no better than before. 3. Changes of preference according to age increase Among the principal foods, increased preferences to boiled rice and cereals were shown but to one-dish meal, bread and rice cake were decreased. Among the subsidiary foods, significantly decreased preference to frying was observed. Irrespectively of the cooking methods, preferences to fish and vegetables were improved. And in the frying and panbroiled foods, deviation of preferences to cooking materials were considerable, which means the fixation of food behavior.

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Hydrogen Production by Catalytic Decomposition of Methane over Rubber-Grade Carbon Blacks (고무용 카본블랙 촉매를 이용하는 메탄분해에 의한 수소 생산)

  • Yoon Ki June;Ryu Bo Hyun;Lee Sang Yup;Han Gui Yong
    • 한국신재생에너지학회:학술대회논문집
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    • 2005.06a
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    • pp.223-226
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    • 2005
  • For $CO_2-free$ hydrogen production and better utilization of the produced carbon, catalytic decomposition of methane over rubber-grade carbon blacks manufactured from coal tar was carried out. The catalytic activities of several domestic carbon blacks were compared. A pelletized carbon black exhibited considerably lower activity and activation energy than the fluffy( loose) carbon black of the same grade. This difference is considered due to the binder that was added during pelletization. For pelletized carbon blacks, a tendency was observed that the activity per unit mass of catalyst increased with the specific surface area of the carbon black. Another tendency was also observed that the activation energy increased with the primary particle size or decrease of the specific surface area.

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Primary Paravertebral Low-Grade Fibromyxoid Sarcoma

  • Lee, Woo-Jin;Park, Chong-Oon;Yoon, Seung-Hwan;Chu, Young-Chae
    • Journal of Korean Neurosurgical Society
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    • v.48 no.5
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    • pp.461-464
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    • 2010
  • The authors report a 58-year-old woman with low-grade fibromyxoid sarcoma primarily located in the right paravertebral area with extension to L4 neural foramen. The patient complained lower back pain with radiating pain along the posterolateral aspect of the right lower leg. She underwent subtotal surgical removal and Cyber Knife therapy. Diagnosis was made by strikingly characteristic microscopic appearance of a bland spindle cell sarcoma which contained numerous giant collagen rosettes and was also supported by immunohistological findings. The diagnostic image findings and literatures are reviewed and discussed.