• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 춘계학술대회 논문집
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• pp.342-347
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• 2002

After the industrial revolution in 20 century, the world are preparing for new revolution that is society with knowledge for a basis such as IT(Information Technology), NT(Nano Technology) and BT(Bio Technology). Recently, NT is applied to various fields that are composed of science, industry, media and semiconductor-micro technology. It has need of IT that is ultra-precision positioning technology with strokes of many hundreds mm and maintenance of nm precision in fields of ultra micro process, ultra precision measurement, photo communication part and photo magnetic memory. Performance test of servo control system that is used ultra-precision positioning system with single plane X-Y stage is performed by simulation with Matlab. Analyzed for previous control algorithm and adapted for modern control theory, dual servo algorithm is developed by minimum order observer, and stability and priority on controller are secured. Through the simulation and experiments on ultra precision positioning, stability and priority on ultra-precision positioning system with single plane X-Y stage and control algorithm are secured by using Matlab with Simulink and ControlDesk made in dSPACE

• Journal of Pharmaceutical Investigation
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• 제33권4호
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• pp.267-272
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• 2003

Herpes simplex virus (HSV) thymidine kinase (TK) has been widely used for suicidal gene therapy in combination with nucleoside analogs such as ganciclovir (GCV). The use of HSV-TK is limited due to the side effect of GCV at high concentrations. Previous studies showed that stable transfectants of mutant HSV-TK with enhanced affinity to GCV were killed at lower GCV concentrations. In this study, we tested whether mutant HSV-TK can provide enhanced suicidal effect when transiently transfected with Epstein-Barr virus (EBV)-based plasmid. EBV-based plasmid which contains OriP and EBNA-1 sequence is well known for a stable episomal maintenance in human cells. Optimal transfection condition was assessed for SNU-638 gastric cancer cell line using polyetylnimine (PEI). Maximum transfection efficiency was achieved when DNA:PEI was 1:3 (w/v). Cytotoxicities of mutant and wild type HSV-TK were compared before and after partially selecting transfected cells. The cells were sensitive to $100\;{\mu}g/ml$ hygromycin. Following GCV treatment, more cells were killed after hygromycin selection than before selection. The mutant HSV-TK showed enhanced cytotoxicity compared with the wild type HSV-TK. Our results suggest that the EBV-based plasmid encoding mutant HSV-TK may be useful to treat the diseases caused by uncontrolled cell proliferation such as cancer and rheumatoid arthritis.

• 인터넷정보학회논문지
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• 제6권3호
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• pp.55-70
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• 2005

이동 통신망 환경에서 이동 호스트에게 멀티캐스트 서비스를 제공하기 위한 방안으로 본 논문에서는 기존의 Xcast++를 계층적 구조를 갖도록 화장한 HXcast++를 제안하였다. 이동 호스트들을 대신하여 DH(Designated Router)이 그룹에 가입하도록 함으로써 이동 호스트의 위치와 상관없이 최적화된 경로로 서비스를 받을 수 있도록 하였으며, 계층적 개념을 도입하여 빈번한 핸드오프로 인한 유지비용을 줄일 수 있도록 하였다. 핸드오프 시 IGMP Membership Query를 기다림 없이 즉각 그룹에 가입할 수 있는 GMA(Group Management Agent)기반 그룹 관리 메커니즘을 제안하였고, 핸드오프 시 발생하는 다량의 패킷손실을 줄이기 위해 Layer 2 Mobile Trigger를 이용하는 fast handoff 기법을 적용하였다. 그룹 가입 지연 동안 발생할 수 있는 패킷 손실은 buffering&forwarding 기법을 이용하여 손실을 줄였다.

• 정보과학회 논문지
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• 제41권10호
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• pp.745-761
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• 2014

기존 교통정보 수집시스템의 낮은 확장성과 높은 비용 등의 문제를 해결하기 위해 WSN 기반의 교통정보 수집 시스템이 최근 많이 연구되고 있다. WSN 기반 시스템은 기존 시스템에 비해 높은 확장성과 낮은 유지보수 비용을 가지는 장점이 있다. 최근에는 자기장센서, 가속도센서, 음향센서 등 다양한 센서를 이용하여 WSN 기반 교통정보수집 시스템 연구가 진행되고 있다. 하지만, 초음파센서를 이용한 WSN 기반 시스템은 아직 연구가 부족한 실정이다. WSN 기반 시스템은 배터리 동작, 낮은 컴퓨팅 파워와 같은 고유 특징으로 인해 에너지절약과 알고리즘의 경량화가 필요하다. 본 논문에서는 상세 모델링과 분석을 통해 도로환경에 따른 초음파 센서의 이상적인 에너지절약 방법을 제시한다. 또한 초음파 데이터를 이용한 차량인식 알고리즘의 경량화를 위한 방법을 제시한다. 제안된 방법은 초소형 마이크로프로세서에 실제 구현되었으며 성능평가를 통해 높은 차량인식 정확성을 보임을 확인하였다.

• Archives of Plastic Surgery
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• 제39권2호
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• pp.138-142
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• 2012

Background : Electrical burns are one of the most devastating types of injuries, and can be characterized by the conduction of electric current through the deeper soft tissue such as vessels, nerves, muscles, and bones. For that reason, the extent of an electric burn is very frequently underestimated on initial impression. Methods : From July 1999 to June 2006, we performed 15 cases of toe tissue transfer for the reconstruction of finger defects caused by electrical burns. We performed preoperative range of motion exercise, early excision, and coverage of the digital defect with toe tissue transfer. Results : We obtained satisfactory results in both functional and aesthetic aspects in all 15 cases without specific complications. Static two-point discrimination results in the transferred toe cases ranged from 8 to 11 mm, with an average of 9.5 mm. The mean range of motion of the transferred toe was $20^{\circ}$ to $36^{\circ}$ in the distal interphalangeal joint, $16^{\circ}$ to $45^{\circ}$ in the proximal interphalangeal joint, and $15^{\circ}$ to $35^{\circ}$ in the metacarpophalangeal joint. All of the patients were relatively satisfied with the function and appearance of their new digits. Conclusions : The strategic management of electrical injury to the hands can be both challenging and complex. Because the optimal surgical method is free tissue transfer, maintenance of vascular integrity among various physiological changes works as a determining factor for the postoperative outcome following the reconstruction.

• 한국도로학회논문집
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• 제12권1호
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• pp.61-69
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• 2010

본 연구에서는 신뢰성 개념을 도입하여 최근 10년간의 수원과 의정부 지역의 일반국도 아스팔트 포장구간의 수명 데이터를 기반으로 적합한 모수적 수명분포 선정과 헤저드 함수 및 생존확률을 추정하였다. 최적 수명분포형을 찾기 위해 확률지 개념을 이용하여 모수를 추정하였으며 적정 확률분포형태의 결정은 Anderson-Darling 통계값을 이용하였다. 그 결과 분석 대상 지역 포장의 수명 데이터를 가장 잘 설명하는 수명분포는 대수정규(Lognormal)분포인 것으로 분석되었다. 또한 본 연구에서 제안한 대수정규분포에 의해 추정된 생존확률함수는 실제 관측값과 차이가 거의 없음을 확인하였다. 본 연구에서 제안한 신뢰성 개념을 이용한 분석 방법은 포장관리 및 유지보수 데이터가 축적되어감에 따라 비교적 용이하게 계속 update가 가능하며 따라서 보다 정확한 포장수명에 대한 신뢰도 값에 접근해 갈 수 있는 이점이 있다.

• 전기학회논문지
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• 제63권3호
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• pp.409-413
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• 2014

GIS partial discharge that occurred in the UHF band signal is effectively detected by the method to IEC60270 5pc the apparent minimum discharge can be detected over the GIS arrangement of the sensor interior and exterior of the UHF in accordance with the optimized position signal by considering the damping ratio is selected so that the signals can be obtained to be mounted. 362kV, 800kV GIS is installed on the internal and external sensors are UHF band signal attenuation is set by measuring the reference value, but the operation, 170kV case 362kV, 800kV on the basis of the measurement data and to be installed and operated. When 170kV per 1Bay by installing the built-in sensor 1 for detecting a partial discharge signal, But, GIS signal attenuation is large in the case of an internal partial discharge signal is not detected in some cases. Where the attenuation is great UHF signal of the sensor by increasing the quantity of partial discharge signals were acquired to allow relocation. The greater the spacing between the sensor and the sensor is applied simplifies the installation and reduces the cost in terms of maintenance of appropriate optimal position is calculated to detect the partial discharge signal is needed. Thus 170kV GIS signal power attenuation of a partial discharge by measuring the UHF sensor, and by relocating the proper position is calculated in accordance with the sensor signal decay rate and minimize the error of omission in detecting a partial discharge signal was optimized.

• 한국실내디자인학회논문집
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• 제27권1호
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• pp.58-67
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• 2018

This study aims to analyze the cases of storage space outside housing unit and propose the activation plan. The issue of storage in residential complex has continued to be reported. This is more salient due to the recent preference trend for small houses, the constant increase of living goods and the limitation of the available space inside housing unit. Although more apartment houses are trying to have individual storage in the exterior space to address these issues, there is still a paucity of the related studies and more studies are required. In this study, we conducted on-site investigation and user interview of each case to propose active usage of the storage space outside housing unit. Result of this study shows that the most crucial factor to improve is 'accessibility' in order to activate the storage space. Storage room should be located close to each household or the individual parking space. The second factor is the size and the structure of the storage room. The sufficient space for keeping and taking large objects out are required. The front of the storage room should have a clogged structure to insure privacy. The third is the provision of suitable support programs such as the system that occupants can check remotely what items are in their storage rooms, garage sale, laundry service, auto cleaning system and rental program. Those programs are required for efficient management and activation of space. Another requirement is to improve environmental factors which include maintenance of optimal temperature and humidity, automatic ventilation system, control of individual lights, and security enhancement. Based on the results of the survey, we provide basic data which can be used for practical space planning to activate exterior storage space of the housing unit. Further surveys are required to develop this study by obtaining more data for generalization.

• 한국환경복원기술학회지
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• 제23권2호
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• pp.33-47
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• 2020

With population losses and stagnant or depressed economies, the local governments embrace shrinkage and accept having a significantly smaller population. Both the initial and ongoing causes of shrinkage hold dramatic effects on the city and its remaining residents. In this context, vacant land increases as an overabundance of unused infrastructure is demolished and municipalities become burdened with increasing maintenance costs of this land. The result is that vacant land often experiences minimal management relative to social norms and have chance to provide a setting for ecological processes with urban rightsizing strategy. Therefore, urban ecosystems undergo major shifts in structure and function. We need to better understand the possibilities of where and how much of houses and land will be abandoned to assist land planners and policymakers to mitigate conflict between optimal ecological and sociological outcomes. This article, therefore, aims to identify distributional characteristics of vacant houses and lands with case study of Mokpo. The study found and verified affecting factors of vacant houses and lands by type through the use of a Maxent model and spatial data that explained housing choice and preference theory. We can predict the vacancies with the spatial variables such as land price, the population ratio over 65, and the distance from security facility. Based on the analysis, the ways of managing housing and land vacancy for sustainable development and ecological restoration method are discussed.

• 한국안전학회지
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• 제33권5호
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• pp.141-149
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• 2018

In a PCB factory, there is a corrosive chemical substance supply system that can causes major leakage accidents. These accidents can give rise to shut down the factory and do residents damage that cause enormous loss of properties. To mitigate these risks, it is necessary to provide a chemical disaster prevention system. Moreover, after considering the situation and environment of the production site, it is of great importance to build an optimal chemical accident prevention system by reflecting risk reduction measures from the point of process design and by assessing quantitative risk based on reliability data. However, because there was no established database of the reliability about facilities and equipment that can be used in the domestic, the business site and consulting organization had being used the reliability data such as USA CCPS(Center for Chemical Process Safety). In these days, Korean institutes are studying on reliability data utilization method of quantitative risk assessment for preventing chemical accidents and domestic utilization algorithms and storage bed of reliability data. This study presents samples of reliability database about the chemical substance supply system that constructed from the history data such as failure, maintenance for 10 years at a PCB factory. Also, this work proposes the safety design criteria for supply facilities of corrosive chemical substance by assessing quantitative risk on the basis of the reliability data.