• 혜화의학회지
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• 제15권2호
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• pp.187-192
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• 2006

Objective : Atopic dermatitis is a prevalent disease. Taeyeol-go(TYG) is a herbal ointment which was expected to useful for treatment of atopic dermatitis. The aim of this study was to evaluate the effect of TYG on atopic dermatitis. Methods : Patients with atopic dermatitis applied TYG twice daily for 1 week. Clinical extent, intensity and subjective symptom were assessed by scoring atopic dermatitis (SCORAD) index before and after treatment. Results : 10 patients(4 male, 6 female), 3 to 37 years of age(mean 14.6${\pm}$9.52 years old), 2 to 31 years of onset(mean 11.4${\pm}$8.54 years), finished study. After treatment extent(p<0.01), intensity(p<0.005), subjective symptom(p<0.002) and total SCORAD index(p<0.002) was significantly decreased than before treatment. Conclusion : These results suggest that TYG is an effective therapeutic method for atopic dermatitis. Further studies in the form of randomized controled trail are needed.

• 한방안이비인후피부과학회지
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• 제28권4호
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• pp.196-207
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• 2015

Purpose : To observe effects of Korean Medicine treatment for genital warts.Methods : In a single private clinic from February 2014 to February 2015, we did retrospective chart review for 326 patients with genital warts who had been treated by Korean Medicine. Korean Medicine treatment included herbal treatment and herbal ointment.Results : A total of 326 patients were enrolled in this study: 62.7%(n=219) male, 32.8%(n=107) female. In the type of diagnosis, new diagnosis was 45.4%(n=148) and recurrent disease was 54.6%(n=178). Complete clearance was achieved 63.2%(n=206) and treatment period was 3.5 months(range:1-9). Partial clearance-good was 15%(n=49), partial clearance-poor was 4.9%(n=16), non response was 16.9%(n=55) and the average treatment period was 4.3 months(range:1-14). In complete clearance group, female and the prevalence of less than 1 year were statistically significant(p<0.05). There was no recurrence of genital warts after TKM treatment during follow-up period(4-13months).Conclusion : This study suggest that Korean Medicine may be an effective treatment for genital warts.

• 한국동물위생학회지
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• 제30권3호
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• pp.421-428
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• 2007

This study was conducted two kinds of aims: 1) to modify the analytical methods (conditions) by high performance liquid chromatography - fluorescence detector for the detection of residual ivermectin in raw milk, 2) to provide basic information for the evaluation of standard of the residual ivermectin in raw milk. It could be considerable that negative ion spectra can be better method in the LC/MS analysis for the detection of residues, Characteristic daughter ions were observed in negative ion spectra, however, linear line was not formed in positive ion one. Three Holstein cows ($500{\pm}10kg$) were applied to commercial ointment of ivermectin just one time at the first day of test, and residues in raw milk were examined for 20day after administration. The limit of detection (LOD) was 0.65ng (n=5) by HPLC/FLD, and recovery rates were $87.85%{\sim}99.47%$. The peak was observed at the 4th day, and residues lasted to the end. Thus ivermectin was prohibited when lactating.

• 한방안이비인후피부과학회지
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• 제20권1호통권32호
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• pp.285-293
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• 2007

Burn is a dermal injury mainly caused by heat. It occurs by flame, boiling water or liquid, steam, sparks, chemicals, radiation, and electricity. Burn is classified as four grades depending on how deep into the skin a person is burned. As the deep second-degree burns possibly leave scars, it can have various physical, psychological, and aesthetical effects with seriousness on the patient with a burn. This report is on the 50-year-old female patient who had a burn with boiling water and a mixture condition of superficial and deep second degree burn. The Korean medical treatments such as Herbal acupuncture, Herbal medication, Acupuncture, Herbal-ointment were used for 17 days to treat effectively the patient with a mixture of superficial and deep second degree burn. It is difficult to find out the report that treats a burn with Korean medical treatment. If more clinical treatments as in this report are proved to be effective, we are able to expect that Korean medical treatment should be a good treatment in burn.

• 한방안이비인후피부과학회지
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• 제29권2호
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• pp.180-186
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• 2016

Anal and perianal condyloma acuminatum(CA), which is a large cauliflower-like tumor, is a manifestation of human papillomavirus (HPV) infection. HPV may be acquired via sexual transmission, vertical transmission or nonsexual contact. It is an uncommon condition in children but the incidence in children has been increasing recently. There are many therapies for CA including chemical or physical destruction, immunological therapy, or a surgical excision. All these procedures have some degree of limitations such as limited clearance rate, high recurrence rate, pain, bleeding, release of potentially infectious aerosols and scar. It may be traumatic mentally to the children as well as physically. Korean Medicine included herbal treatment and herbal ointment for CA is no pain, and it doesn't need an anesthesia. We present a case of anal and perianal CA in a 2 years old boy that was treated successfully with Korean Medicine, with no recurrence during the follow up 3 months.

• 한방안이비인후피부과학회지
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• 제30권4호
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• pp.25-36
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• 2017

Objectives : The aim of this study is to report the effect of Capsosiphon fulvescens(Maesangi) extract(MSE) on contact dermatitis(CD). Methods : CD induced by Dermatophagoides farinae body(Dfb) in NC/Nga mice. 4% sodium dodecyl sulfate(SDS) $150{\mu}l$ and Dfb(10mg/ml) ointment 100mg were topically treated twice a week for four weeks. MSE 200 mg/kg was topically treated every 4weeks. Every week, we examined the skin lesions, weight of spleen and lymph node, epidermal thickness, production of Tumor necrosis factor-alpha($TNF-{\alpha}$) and interleukin-6(IL-6). Results : MSE reduced features of Dfb-induced skin lesions, weight of spleen and production of $TNF-{\alpha}$. MSE significantly reduced weight of lymph node, epidermal thickness, number of mast cells and production of IL-6. Conclusions : MSE may have a potential therapeutic effects for CD by suppressing allergic inflammation.

• 생약학회지
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• 제43권1호
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• pp.59-65
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• 2012

Atopic dermatitis (AD) is a common chronic inflammatory disease of preceding the development of allergic disorders. The incidence of AD is increasing and it causes problems with administrative costs. Therefore, no side effects, easyto- use development of AD treatment is needed. The aim of this study was to evaluate whether PBMCAT, a functional extract from herbal complex was effective to treat the AD mice. AD was induced by patching ovoalbumin on the backside in BALB/ c mouse and then mice were topically treated with PBMCAT. Elidel $cream^{(R)}$ (pimecrolimus, PL) was used as a control. Scratching counts (SC) and clinical skin severity (CSS) were measured, and total serum IgE level was also measured. After inducing AD, SC and CSS were increased. The total serum IgE level was also increased in AD-induced mice. Treatment with PBMCAT significantly decreased SC, CSS, and serum IgE concentration in mice. Especially, treatment of PBMCAT 0.1% in BALB/c mice more effected than PL. These results suggest that the ointment of PBMCAT may enhance the process of AD healing by influencing phase of allergic reacting.

• 대한수의학회지
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• 제23권1호
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• pp.123-128
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• 1983

This study was conducted to evaluate the modified drug sensitivity test for the shortening of detection time and clinical application. The results obtained were summarized as follows. 1. Inhibitory zone in 6 strains of Staphylococcus and Escherichia coli tested to sensitivity teat were reached at 100% between 2 and 6 hours. 2. The sensitivity test of Staphylococcus A, B and E. coli No. 2, No. 3 to antibacterial ointment drugs were strong positive(+++), but Staphylococcus A. A. and E. coli No. 1 were mild resistant(+). 3. The sensitivity test of Staphylococcus A. B and E. coli No. 2, No. 3 to antibacterial injection drugs in 6 hours after treatment were strong positive(+++), and Staphylococcus A. A. and E. coli No. 1 were moderate positive(++). 4. This modified method was detected 86% degree of sensitive between 7 to 12 hours after treatment. 5. We think this modified method was more practical compare to other methods.

• 대한한방부인과학회지
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• 제20권3호
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• pp.229-237
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• 2007

Purpose: The purpose of this study was to report the clinical application of traditional korean medicine(TKM) treatment to hyeolheopungyeol type of dermatoses gravidarum. Methods: We experienced four patients who had been suffering from itching, plaque, erythema during pregnancy. They had already been treated with antihistamine or ointment, but they were not improved. We diagnosed their case as hyeolheopungyeol type of dermatoses gravidarum, and treated with sopungsan-gaml. Results: After TKM treatment, itching, plaque and erythema were alleviated or resolved. And they gave birth to a healthy baby. Conclusion: The results indicate that TKM, sopungsan-gami can be effective for the management of hyeolheopungyeol type of dermatoses gravidarum.

• 한방안이비인후피부과학회지
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• 제24권2호
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• pp.87-95
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• 2011

Objective : Subcorneal pustular dermatosis is a rare, chronic neutrophilic dermatoses that was first described in 1956. The eruption is characterized by flaccid pustules grouped in a circinate pattern on normal or erythematous skin. We treated a case of subcorneal pustular dermatosis in one patient; there have been no former reports of this disease treated by oriental medicine. We present this case because we considered it to be useful as a possible Oriental medicine treatment for subcorneal pustular dermatosis, and something that canbe used for further study of neutrophilic dermatoses. Method : We used herbal medication, acupuncture, herbal wet dressing, herbal ointment, cupping therapy and phototherapy during treatment. We assessed symptoms during treatment and also carried out blood tests through out. Result : We observed and treated a case of subcorneal pustular dermatosis patient and after treatment the patient's objective and subjective symptoms showed noticeable improvement. Conclusion : We suggest that subcorneal pustualr dermatosis can be treated by Oriental medicine therapy effectively. We expect these study results will help provide useful evidence of Oriental medicine as an effective treatment for subcorneal pustualr dermatosis.