• Nuclear Engineering and Technology
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• v.55 no.2
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• pp.452-459
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• 2023

The core power control is an important issue for the study of dynamic characteristics in China initiative accelerator driven subcritical system (CiADS), which has direct impact on the control strategy and safety analysis process. The CiADS is an experimental facility that is only controlled by the proton beam intensity without considering the control rods in the current engineering design stage. In order to get the optimized operation scheme with the stable and reliable features, the variation of beam intensity using the continuous and periodic control approaches has been adopted, and the change of collimator and the adjusting of duty ratio have been proposed in the power control process. Considering the neutronics and the thermal-hydraulics characteristics in CiADS, the physical model for the core power control has been established by means of the point reactor kinetics method and the lumped parameter method. Moreover, the multi-inputs single-output (MISO) logical structure for the power control process has been constructed using proportional integral derivative (PID) controller, and the meta-heuristic algorithm has been employed to obtain the global optimized parameters for the stable running mode without producing large perturbations. Finally, the verification and validation of the control method have been tested based on the reference scenarios in considering the disturbances of spallation neutron source and inlet temperature respectively, where all the numerical results reveal that the optimization method has satisfactory performance in the CiADS core power control scenarios.

• Journal of Digestive Cancer Research
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• v.4 no.1
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• pp.1-9
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• 2016

The abundance of multi-drug resistance ATPase binding cassette and deranged self-renewal pathways shown in cancer stem cells (CSCs) played a crucial role in tumorigenesis, tumor resistance, tumor recurrence, and tumor metastasis. Therefore, elucidation of CSCs biology can improve diagnosis, enable targeted treatment, and guide the follow up of GI cancer patients. In order to achieve chemoquiescence, seizing cancer through complete ablation of CSCs, CSCs are rational targets for the design of interventions that will enhance responsiveness to traditional therapeutic strategies and contribute in the prevention of local recurrence as well as metastasis. However, current cancer treatment strategies fail to either detect or differentiate the CSCs from their non-tumorigenic progenies mostly due to the absence of specific biomarkers and potent agents to kill CSCs. Recent advances in knowledge of CSCs enable to produce several candidates to ablate CSCs in gastrointestinal (GI) cancers, especially cancers originated from inflammation-driven mutagenesis such as Barrett's esophagus (BE), Helicobacter pylori-associated gastric cancer, and colitis-associated cancer (CAC). Our research teams elucidated through revisiting old drugs that proton pump inhibitor (PPI) and potassium competitive acid blocker (p-CAB) beyond authentic acid suppression, chloroquine for autophage inhibition, sonic hedgehog (SHH) inhibitors, and Wnt/β-catenin/NOTCH inhibitor can ablate CSCs specifically and efficiently. Furthermore, nanoformulations of these molecules could provide an additional advantage for more selective targeting of the pathways existing in CSCs just like current molecular targeted therapeutics and sustained action, while normal stem cells intact. In this review article, the novel approach specifically to ablate CSCs existing in GI cancers will be introduced with the introduction of explored mode of action.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.44 no.12
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• pp.1087-1094
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• 2016

The responsibility of the vehicle holding device (VHD) is to hold the launch vehicle while it is stayed on launch pad and release the holding mechanism to allow a lift-off of launch vehicle at a moment of lift-off. During a release of the holding mechanism, in order to prevent the Ka doing a doing a doing mode which is vertical oscillation of entire liquid propellant and very severe for vehicle structure, gradual release of holding force is required. Also, a release operation of all 4 VHD should be synchronized very precisely. In this study, to comply the "gradual release and synchronized operation requirement", concept of VHD hydraulic system using an accumulator, pyro valve and orifice to control speed of hydraulic cylinder is proposed instead of using complicated hydraulic components. Then through multi-body dynamic analysis and computational hydraulic analysis, a size of orifice to meet a target speed of hydraulic cylinder is calculated. Through this study, simple and reliable VHD hydraulic system complying requirements is designed.

• Korean Journal of Optics and Photonics
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• v.16 no.3
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• pp.248-253
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• 2005

We designed and fabricated a compact multi-mode interference (MMI) wavelength demultiplexer using the concept of 'Improved Quasi-State' modes. The output power and extinction ratio were improved by utilizing modal phase error which is specially occurred in low-index contrast. For a designed demultiplexer, the mode propagation analysis with effective index approximation shows significant improvement of extinction ratio to -25 dB for both $1.31{\mu}m\;and\;1.51{\mu}m$ wavelength region and the split-length was reduced about 1/5 of other MMI devices. The fabricated device shows successful characteristics for both 1.31 and $1.55{\mu}m$ wavelengths. These results demonstrate the potential of low-index materials system and the embossing process for photonic integrated circuits.

• Journal of Energy Engineering
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• v.20 no.3
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• pp.185-190
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• 2011

This paper describes design, fabrication, and evaluation of the conduction cooled high temperature superconducting (HTS) magnet for superconducting magnetic energy storage (SMES). The HTS magnet is composed of twenty-two of double pancake coils made of 4-ply conductors that stacked two Bi-2223 multi-filamentary tapes with the reinforced brass tape. Each double pancake coil consists of two solenoid coils with an inner diameter of 500 mm, an outer diameter of 691 mm, and a height of 10 mm. The aluminum plates of 3 mm thickness were arranged between double pancake coils for the cooling of the heat due to the power dissipation in the coil. The magnet was cooled down to 5.6 K with two stage Gifford McMahon (GM) cryocoolers. The maximum temperature at the HTS magnet in discharging mode rose as the charging current increased. 1 MJ of magnetic energy was successfully stored in the HTS magnet when the charging current reached 360A without quench. In this paper, thermal and electromagnetic behaviors on the conduction cooled HTS magnet for SMES are presented and these results will be utilized in the optimal design and the stability evaluation for conduction cooled HTS magnets.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.17 no.8 s.111
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• pp.773-787
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• 2006

An airborne radar is an essential aviation electronic system for the aircraft to perform various civil and/or military missions in all weather environments. This paper presents the design, development, and test results of the multi-mode X-band pulsed Doppler radar system test model for helicopter-borne flight test. This radar system consists of 4 LRUs(Line-Replacement Unit), which include antenna unit, transmitter and receiver unit, radar signal & data processing unit and display Unit. The developed core technologies include the planar array antenna, TWTA transmitter, coherent I/Q detector, digital pulse compression, MTI, DSP based Doppler FFT filter, adaptive CFAR, moving clutter compensation, platform motion stabilizer, and tracking capability. The design performance of the developed radar system is verified through various ground fixed and moving vehicle test as well as helicopter-borne field tests including MTD(Moving Target Detector) capability for the Doppler compensation due to the moving platform motion.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.4
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• pp.475-483
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• 2012

This paper presents new type of the hybrid supply modulator for the next reconfigurable transmitters. The efficiency of the hybrid supply modulator is one of the most important performance. For enhancement the efficiency, multi-switching structure in the hybrid supply modulator is employed. Additionally, input envelope signal sensing stage is employed for implementation multi-mode operation. To compare the performance of the proposed hybrid supply modulator, the conventional hybrid supply modulator is also designed. The measured efficiency of the proposed hybrid supply modulator is 85 %/84 %/79 % for EDGE/WCDMA/LTE signals which have 384 kHz/3.84 MHz/5 MHz bandwidth, respectively. The efficiency of the proposed hybrid supply modulator is higher than the conventional hybrid supply modulator. Therefore, this structure shows good candidate for the reconfigurable transmitters.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.34 no.6
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• pp.713-719
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• 2001

The aim of this study is to check the application criteria of the conventional techniques and clarify the effects of breaker depth, seabed conditions on the stability in relation to the effects of uncertainty of storm duration and directional irregular waves. The typical damage modes were divided by the direct wave force on the armor unit and by the local scouring around the toe of a breakwater head by the model experiments. The destruction modes are defined, and some criteria on the damage modes and scouring/deposition at the toe of a breakwater head in relating the wave-bottom-structural conditions can be checked using the multi-directonal irregular wave generator system. According to the results, it is emphasized that the 3-D effects on the stability should be analyzed in the design of multi-purpose/function coastal structures in consideration of the evaluation of spatial variation of damage modes and hydraulic characteristics as well as the wave distribution along the structures.

• Journal of IKEEE
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• v.24 no.1
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• pp.161-169
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• 2020

In order to reduce the manufacturing cost of MCU chips used in applications such as wireless chargers and USB-C, compared to DP-EEPROM (Double Poly EEPROM), which requires 3 to 5 additional process masks, it is even more necessary MTP(Multi-Time Programmable), which is less than one additional mask and have smaller unit cell size. In addition, in order to improve endurance characteristics and data retention characteristics of the MTP memory cell due to E/P(Erase / Program) cycling, the distribution of the V_TP(Program Threshold Voltage) and the V_TE(Erase Threshold Voltage) needs to be narrow. In this paper, we proposed a current-type BL S/A(Bit-Line Sense Amplifier) circuit, WM(Write Mask) circuit, BLD(BL Driver) circuit and a algorithm, which can reduce the distribution of program and V_T and erase V_T, through compare the target current by performing the erase and program pulse of the short pulse several times, and if the current specification is satisfied, the program or erase operation is no longer performed. It was confirmed that the 256Kb MTP memory fabricated in the Magnachip semiconductor 0.13㎛ process operates well on the wafer in accordance with the operation mode.

• Journal of the Korean earth science society
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• v.21 no.6
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• pp.719-733
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• 2000

Normally, a digital geologic map can be defined as mappable one whose spatial information with geographic information details and geologic database attribute, recorded in a digital format that is readable by computer. It shows fundamentally two different conceptual perspectives: cartography for digital mapping and analysis for geo-data processing. While, as both aspects basically relate to natural entities and their interpretation of complex features fused with multi-sources, digital geo-data mapping or geologic mapping, it should be distinguished from digital mapping in engineering such as UIS(Urban Infomation System) and AM/FM(Automated Mapping/Facilities Management). Furthermore, according to short-cycled development of GIS(Geographic Information System) software architecture based on IT(Information Technology) and wide expansion of GIS applications' fields, the importance of domain analysis and application model is emphasized at digital geologic informatizaion. In this paper, first terms and concepts of geo-data model with general data modeling aspects are addressed, and then case histories for geo-data modeling and several approaches for data modeling in GIS application fields are discussed. Lastly, tentative conceptual geo-data modeling by using UML(Unified Modeling Language) of OO(Object-oriented) concepts with respect to USGS/AASG geo-data mode is attempted. Through this approach, the main benefits for standardization and implementation lineage with conceptual model in consideration to reusability are expected. Conclusively, it is expected that geo-information system and its architecture by UML is the new coming key approach for the GIS application in geo-sciences.