• The Korean Journal of Food And Nutrition
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• v.28 no.5
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• pp.774-781
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• 2015

The objective of the present study was to determine the total phenol and flavonoid contents and to evaluate the antioxidant potential, of different solvent extracts (ethyl acetate, n-butanol, chloroform, and water) from Robus idaeus in various radical scavenging models (DPPH activity, superoxide dismutase (SOD) activity, reducing power, and nitrite scavenging activity), along with their antimicrobial potential. Measurement of total phenol and flavonoid content of the ethyl acetate extract of R. idaeus was found to be significantly higher than those of the other extracts. The ethyl acetate extract (at a concentration of $1,000{\mu}g/mL$) showed significantly higher reducing power and DPPH radical scavenging activity as compared to the other extracts. Results were dose-dependent. Moreover, the ethyl acetate extract of R. idaeus ($1,000{\mu}g/mL$) showed potent antioxidant efficacy ($85.5{\pm}1.18%$) as evidenced by nitrite scavenging ability at pH 1.2. All solvent extracts of R. idaeus showed lower SOD-like activity (13.72~20.54%). In addition, the antimicrobial activity of all solvent extracts except water extract showed strong inhibition (inhibitory zones in mm) of Staphylococcus aureus ($19.40{\pm}1.00mm$) and Bacillus cereus ($20.50{\pm}0.21mm$) growth. In particular, ethyl acetate extracts (100 mg/mL) showed antimicrobial activity comparable to that of tetracycline (0.01 mg/mL), which was used as a positive control. The results of this study indicate that the ethyl acetate extract of R. idaeus is a natural antioxidant and antimicrobial, with enriched phenols and flavonoids concentration, that has potential in the development of health-enhancing food products.

• Biomedical Science Letters
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• v.20 no.3
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• pp.156-161
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• 2014

It has been reported that safflower seeds have preventive effects against osteoporosis. Recently, safflower buds (SB) were found to have more useful functional ingredients than safflower seeds. In the current study, we evaluated the anti-osteoporosis effects of SB diet in ovariectomized (OVX) rats. The rats were divided into five groups; sham operated group, OVX alone group, OVX plus $17{\beta}$-estradiol ($E^2$ $10{\mu}g/kg$, i.p.) and OVX plus SB diet feeding group (0.3% or 1%). Feeding of SB diet (0.3% or 1%) to OVX rats markedly increased bone mineral density (BMD) of femurs, compared to the OVX group. The OVX rats exhibited a marked increase in trabecular separation (Tb.Sp) and this change was inhibited by the feeding of SB diet, similar to that seen with OVX+E2 group. Moreover, feeding of SB diet to OVX rats decreased the markers of bone turnover, including osteocalcin and alkaline phosphatase (ALP). These results suggest that SB extract has a bone sparing effect in OVX-induced trabecular bone loss and prevents deterioration of bone microarchitecture by suppressing the rate of bone turnover. Therefore, SB may be useful for preserving bone mass and structure in estrogen deficient women with a potential role in reducing postmenopausal osteoporosis.

• Journal of the Korea Convergence Society
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• v.9 no.2
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• pp.33-42
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• 2018

The purpose of this study is to identify the degree of dating violence experience, violence tolerance, and social problem solving ability of nursing college students and to investigate the relationship between them. 219 college students from nursing in 5 universities of Chungcheong region were convenience selected for the study. Data were collected through self-report questionnaires. Data were analyzed by t-test, ${\chi}^2$ test and Partial correlation coefficients using the SPSS 20.0 program. As a result, nursing college student's the more experience dating violence, the higher the tolerance for dating violence(r=0.31, p<.001), the higher the tolerance of dating violence is, the more negative the ability to solve social problems(r=-0.26, p<.001), and the degree of their departmental satisfaction and drinking are related to the violence of dating violence. Therefore, it provided a rational basis for the establishment of a dating violence preventive education and training program to raise awareness of dating violence tolerance and social problem solving abilities in order to prevent dating violence.

• Journal of Industrial Convergence
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• v.20 no.4
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• pp.39-46
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• 2022

This descriptive survey study identified the factors influencing the abiliy of healthcare perceived by high school students. The survey was conducted from May 7, 2020, to Sep. 17, 2020 for 119 high school students in City D. SPSS WIN 22.0 program was used to for t-test and one-way ANOVA with Pearson's correlation coefficients and hierarchical regression analysis. The ability of healthcare perceived by high school students had a static correlation with the sub-domains of family function, that is, family cohesion(r=.65, p<.001) and family adaptability(r=.54, p<.001). For male students(β=.17, p=.012), those who reported a high level of perceived health status showed a high level of ability of healthcare(β=.25, p<.001). Significant influencing factors on high school students' health management ability were identified as gender (β=.17), their own health status perception (β=.23), and family cohesion (β=.45), and the explanatory power of the model was 50%. appear. Further research is hereby suggested for validation of the mediating role and effects of health care education programs to improve the family function perceived by high school students, encourage their practicing of health care management and help them to enter into healthy adulthood.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.1135-1141
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• 2023

The purpose of this study was to investigate the effect of Grit and Self-elasticity on Carrer Identity of nursing students. Data were collected among 193 nursing students in G city, from Sep 4 to 15 2023. The collected data was analyzed a using t-test, One way ANOVA, Pearson correlation coefficient and Stepwise multiple regression using SPSS 20.0 WIN program. The results revealed that the average score for Self-elasticity was 3.42±0.45, Grit was 3.63±0.60, Carrer Identity was 4.06±0.79. students acquired Self-elasticity by gender as per general characteristics. The Carrer Identity showed statistically significant differences in gender. There was a statistically significant positive correlation between the Carrer Identity of Self-elasticity(r=.370, p=.000), and Grit(r=.283, p=.000). Carrer Identity showed Models including the variables, Self-elasticity, Gender, Grit explained 22.6% of the variance in the Carrer Identity stress. Based on the outcome of this study, steps should be taken to design intervention program that emphasize a improve Carrer Identity for nursing students.

• The Journal of Society for e-Business Studies
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• v.20 no.3
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• pp.29-46
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• 2015

Examined how it varied the knowledge network of the country along with R&D changes in planning policy for the research and development of government. Therefore, in this study, chronological Analysis analyzed separately the network between each entity of participate in the industry fusion source technology development business of industry trade and Energy. Planning policy of industrial fusion source technology development business, to change the starting point before and after 2012, before 2012 from selected planning issues at the center "planning committee" and in 2012 'PD' changes to a system for planning issues around. First of all, an attempt to analyze the R&D network based on the "planning committee" current situation of 2009~2011, from 2012 to analyze the variation of the R&D network with the introduction of the 'PD' system after it was analyzed by dividing the time in the current state of up to 2013. The results of the analysis, since the PD system was introduced, such as self-relationship (the form of planning user to run directly challenges the person was planning to challenge participants)is greatly improved, I was able to grasp the effect became clear. The more the self-relation, and the budding scholars considering that there is inequality of the planning, the introduction of the PD scheme, it can be seen to have resulted in a positive effect. These studies, quantitatively analyzed to improve the results to the effects associated with changes in the planning policy of the government, I think that there is a meaning in terms of presenting the future direction of R&D policy.

• Journal of Korean Clinical Nursing Research
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• v.27 no.1
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• pp.66-76
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• 2021

Purpose: This descriptive study aimed to explore the performance, nurses' perception, and influencing contexts of intentional rounding (IR), and to identify the factors influencing the performance of IR. Methods: 498 questionnaire responses were collected from clinical nurses with more than six months of work experiences in general wards performing IR in a general hospital. Results: The mean scores of the performance, nurses' perception, and influencing contexts of IR were 3.81(±0.68), 3.46(±0.42), and 3.79(±0.51) out of 5.00, respectively. There were significant differences in performance (F=20.51, p<.001) and nurses' perception (F=4.96, p=.001) based on the work department. There were significant differences in the influencing contexts based on age (F=6.02, p=.003) and the length of clinical experience in the ward (F=3.36, p=.010). Performance and nurses' perception(r=.42, p<.001), performance and influencing contexts (r=.46, p<.001), and nurses' perception and influencing contexts (r=.58, p<.001) showed a statistically positive correlation. Work unit (F=10.45, p<.001), nurses' perception of the benefits to patients (F=-2.46, p=.014) and to nurses (F=4.34, p<.001), and influencing contexts at the individual (F=7.77, p<.001) and department levels (F=2.99, p=.003) were found to be significant factors on the performance of IR. Conclusion: It is necessary to support the education programs and active participation of nurses in their role as leaders to raise their awareness regarding the benefits of IR. Furthermore, there is a need to adapt the IR protocol according to the unique characteristics of each unit and evaluate the effectiveness.

• Journal of Korean Academy of Nursing Administration
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• v.13 no.3
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• pp.285-292
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• 2007

Purpose: The purpose of this study was to identify the factors influencing the nursing professional values(NPV) of college nursing students. Methods: A convenience sample of 274 subjects was recruited from the department of nursing at a college. The survey was conducted from May 29 to Jun 20 2006. The data was analyzed using descriptive statistics, Pearson correlation coefficients, and stepwise multiple regression with SPSS/WIN 10.1. Results: The average item score of NPV, satisfaction, socialization, self-esteem were 3.60, 3.00, 2.74, and 2.71. The NPV of nursing students showed a significantly positive correlation to speciality satisfaction(r=.28-.46), socialization(r=.13-.46), and self-esteem(r=.12-.15). The significant factors influencing NPV of nursing students were service, curriculum satisfaction, social perception satisfaction, leadership & popularity, and sociability, which explained about 37.5%. Conclusions: Therefore, on the basis of this study's result, when nursing educational programs are developed to make positive NPV, these factors need to be considered.

• Fisheries and Aquatic Sciences
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• v.14 no.3
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• pp.174-178
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• 2011

This study aimed to determine the degree of hydrolysis and angiotensin-I-converting enzyme (ACE)-inhibitory activity of Giant Jellyfish Nemopilema nomurai (jellyfish) hydrolysates. The degree of hydrolysis using six proteolytic enzymes (Alcalase, Flavozyme, Neutrase, papain, Protamex, and trypsin) ranged from 13.1-36.8% and the inhibitory activities from 20.46-79.58%. Using papain hydrolysate, we newly isolated and characterized ACE-inhibitory peptides with a molecular weight of 3,000-5,000 Da that originated from jellyfish collagen. The purified peptide (FII-b) was predicted to be produced from an alpha-2 fragment of the type IV collagen of jellyfish. The N-terminal sequence of FII-b was Asp-Pro-Gly-Leu-Glu-Gly-Ala-His-Gly- and showed 87% identity to the collagen type IV alpha-2 fragment of Rattus norvegicus and a predicted protein from Nematostella vectensis, indicating that the ACE-inhibitory peptide originated from the collagen hydrolysate and had an $IC_{50}$ value of 3.8 ${\mu}g$/mL. The primary structure of the fragment is now being studied; this peptide represents an interesting new type of ACE inhibitor and will provide knowledge of the potential applications of jellyfish components as therapies for hypertension.

• Journal of Life Science
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• v.20 no.10
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• pp.1427-1432
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• 2010

This study was carried out to evaluate neutralization effects against WSSV using antiserum produced from recombinant envelop protein, rVP466 of WSSV. The VP466 gene of WSSV was cloned into pCold I expression vector and rVP466 was expressed in E. coli RIPL. The antiserum against rVP466 was produced in white rabbits (New Zealand white rabbit). The specific immunoreactivity to the antigen, rVP466, was confirmed by Western blot. The constant amounts of WSSV at $1{\times}10^4$ diluted stocks were mixed with various antiserum concentrations and then injected to the muscle of shrimp, Penaeus chinensis, for the neutralization challenge. The shrimps challenged with WSSV as a positive control and those with the mixture of WSSV and preimmune serum as a preimmune control showed 100% cumulative mortality at 17 days post challenge and 83% at 25 days post challenge, respectively. The shrimps challenged with 3 different mixtures of WSSV and rVP466 antiserum at ratios of 1:0.01, 1:0.1 and 1:1 showed 73%, 53% and 46% cumulative mortalities at 25 days post challenge, respectively. These results indicated that WSSV could be neutralized by the rVP466 antiserum. These results suggest that envelop protein VP466 is involved in the initial step of WSSV infection in shrimp.