• Archives of Plastic Surgery
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• 제35권1호
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• pp.7-12
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• 2008

Purpose: Since the report of artificial dermis manufacturing method using collagen by Yannas in 1980, collagen has been effectively used as dermal substitute with its merits such as, lower antigeneicity, controllable biodegradation rate, and minimal inflammatory cytotoxic properties in the dermal tissue engineering field. However, weak mechanical durability was the main drawback of collagen dermal substitute. To improve its stability, mechanical or chemical cross-linking was used. Despite of such process, its clinical use was restricted due to weak durability. To improve the durability of collagen matrix, we designed elastin-incorporated collagen matrix and compared its durability with conventional collagen matrix. Methods: 15mm diameter with 4mm thick collagen dermal matrix was made according to Yannas protocol by mixing 0.5% bovine collagen and chondroitin-6-sulfate followed by degassing, freeze drying, dehydrodermal cross-linking and chemical cross-linking procedure. In elastin incorporated collagen matrix, same procedure was performed by mixing elastin to previous collagen matrix in 4:1 ratio(collagen 80% elastin 20%). In comparison of the two dermal matrix in vitro tests, matrix contracture rate, strain, tensile strength, was measured and stiffness was calculated from comparative analysis. Results: In terms of matrix contracture, the elastin-incorperated added collagen dermis matrix showed 1.2 times more contraction compared to conventional collagen matrix. However, tensile strength showed 1.6 times and stiffness showed 1.6 times increase in elastin-incorporated matrix. Conclusion: Elastin incorperated collagen matrix manufactured by our team showed increased durability due to improvement in tensile strength and stiffness compared to previous collagen matrix($Integra^{(R)}$).

• 한국소음진동공학회논문집
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• 제26권2호
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• pp.179-186
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• 2016

This paper presents a numerical method that can evaluate the effect of crack for the in-plane bending vibration of Timoshenko beam. The method is a transfer matrix method that the element transfer matrix is deduced from the element dynamic stiffness matrix. An edge crack is expressed as a rotational spring, and then is formulated as an independent transfer matrix. To demonstrate the accuracy of this theory, the results computed from the present are compared with those obtained from the commercial finite element analysis program. Based on these comparison results, a parametric study is performed to analyze the effects for the size and locations of crack.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2006년도 한국컴퓨터종합학술대회 논문집 Vol.33 No.1 (A)
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• pp.400-402
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• 2006

Matrix multiplication is an important problem in linear algebra. its main significance for combinatorial algorithms is its equivalence to a variety of other problems, such as transitive closure and reduction, solving linear systems, and matrix inversion. Thus the development of high-performance matrix multiplication implies faster algorithms for all of these problems. In this paper. we present a quantitative comparison of the theoretical and empirical performance of key matrix multiplication algorithms and use our analysis to develop a faster algorithm. We propose a Hybrid approach on Winograd's and Strassen's algorithms that improves the performance and discuss the performance of the hybrid Winograd-Strassen algorithm. Since Strassen's algorithm is based on a $2{\times}2$ matrix multiplication it makes the implementation very slow for larger matrix because of its recursive nature. Though we cannot get the theoretical threshold value of Strassen's algorithm, so we determine the threshold to optimize the use of Strassen's algorithm in nodes through various experiments and provided a summary shown in a table and graphs.

• Current Optics and Photonics
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• 제5권3호
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• pp.322-328
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• 2021

In this paper, a pretreatment method for a matrix in convex optimization is proposed to optimize the spectral reconstruction process of a disordered dispersion spectrometer. Unlike the reconstruction process of traditional spectrometers using Fourier transforms, the reconstruction process of disordered dispersion spectrometers involves solving a large-scale matrix equation. However, since the matrices in the matrix equation are obtained through measurement, they contain uncertainties due to out of band signals, background noise, rounding errors, temperature variations and so on. It is difficult to solve such a matrix equation by using ordinary nonstationary iterative methods, owing to instability problems. Although the smoothing Tikhonov regularization approach has the ability to approximatively solve the matrix equation and reconstruct most simple spectral shapes, it still suffers the limitations of reconstructing complex and irregular spectral shapes that are commonly used to distinguish different elements of detected targets with mixed substances by characteristic spectral peaks. Therefore, we propose a special pretreatment method for a matrix in convex optimization, which has been proved to be useful for reducing the condition number of matrices in the equation. In comparison with the reconstructed spectra gotten by the previous ordinary iterative method, the spectra obtained by the pretreatment method show obvious accuracy.

• Journal of Pharmaceutical Investigation
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• 제31권1호
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• pp.37-41
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• 2001

Various characteristics of polyethylene oxide (PEO) are useful for drug delivery systems. In this study, PEO was used as a sustained release matrix system containing cefatrizine propyleneglycol (Cefa-PG) which is a new semi-synthetic broad-spectrum and orally active cephalosporin. Five kinds of sustained release matrix tablets were formulated with various content of PEO and other ingredients. And three types of matrix tablets were formulated of which compositions were the same but the hardness was different. It was found that PEO content influenced drug release rate. Increasing PEO content, the drug release rate from matrix tablets was decreased. In addition, Avicel, one of the ingredients of matrix components, changed the drug release from the sustained release PEO matrix tablets. With increasing Avicel content, the rate of drug release was increased. For the effect of hardness of matrix tablets, the rate of drug release is decreased with increasing hardness. In comparison of bioavailability parameters after oral administration of Cefa-PG PEO matrix tablets and general Cefa-PG capsule in beagle dog, the sustained release PEO matrix tablets is more useful than a general dosage form. $AUC^{0-12}$ of the sustained release PEO matrix tablet and the general dosage form was 1.16 and 0.644 respectively.

• 한국소음진동공학회논문집
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• 제26권1호
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• pp.75-81
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• 2016

In this study, a transfer matrix method in which can produce an infinite number of accurate natural frequencies using a single element for the bending vibration of rotating Bernoulli-Euler beam with linearly reduced width, is developed. The roots of the differential equation in the proposed method are calculated using the Frobenius method in the power series solution. To demonstrate the accuracy of the method, the calculated natural frequencies are compared with the results given by using the commercial finite element analysis program(ANSYS), and the comparison results between these two methods show the excellent agreement. Based on the comparison results, a parametric study is performed to investigate the effect of the centrifugal forces on the non-dimensional natural frequencies for rotating beam with the variable width.

• 한국지리정보학회지
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• 제21권2호
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• pp.44-55
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• 2018

기후변화에 대응하기 위한 정책 수립과 이행을 위해 온실가스 인벤토리 작성의 중요성이 대두되고 있다. 이에 따라, 토지이용 항목과 변화들에 대해 공간 명시적으로 나타낸 Approach 3 수준의 Land Use, Land-Use Change and Forestry(LULUCF) 매트릭스 구축 필요성이 제기되고 있다. 본 연구에서는 LULUCF 매트릭스의 산림 항목을 중심으로 연속지적도, 중분류 토지피복지도, 임상도, 도시생태현황지도를 활용하여 LULUCF 매트릭스 구축에 적합한 공간정보를 검토하였다. 각 공간정보에 대한 분류 속성 비교를 실시하였고 충청남도 보령시를 대상으로 양적(면적) 비교, 질적(특성) 비교를 실시하였다. 양적 비교 결과 산림의 면적이 임상도에서 최고 50.42%($303.79km^2$), 지적도에서 최저 46.09%($276.65km^2$)의 차이를 보였다. 질적 비교 결과 자료 구축 범위 차이, 자료 구축 목적 차이, 분류 항목 차이, 일필일목의 원칙 적용 여부의 차이, 자료구축 시기 차이 등 5가지 질적 특성의 차이를 확인하였다. 연구 결과 도시생태현황지도가 LULUCF 매트릭스 구축에 가장 적합한 공간 정보로 판단되었으나 전국구축이 되어있지 않은 한계로 토지피복지도가 가장 적합한 것으로 검토되었다. 또한, 도시생태현황지도, 임상도, 토지피복지도 등을 서로 종합하여 LULUCF 매트릭스를 구축하게 될 경우 각 공간정보의 한계를 보완할 수 있을 것으로 사료된다. 추후 전국토를 대상으로 하는 1:5,000 수준의 세분류 토지피복지도 및 도시생태현황지도가 완료될 경우 LULUCF 매트릭스 작성의 정밀도를 향상시킬 수 있을 것으로 판단된다.

• 전자공학회논문지B
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• 제31B권5호
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• pp.1-11
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• 1994

In computer graphics since objects atre constructed by lines and curves, the high-speed curve generator is indispensible for computer aided design and simulatation. Since the functions of graphic generation can be represented as a series of matrix operations, in this paper, two kind of the high-speed Bezier curve generator that uses matrix equation and a recursive relation for Bezier polynomials are designed. And B-spline curve generator is designed using interdependence of B-spline blending functions. As the result of the comparison of designed curve generator and reference [5], [6] in the operation time and number of operators, the curve generator with 1-dimensional systolic array processor for matrix vector operation that uses matrix equation for Bezier curve is more effective.

• 한국세라믹학회지
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• 제30권6호
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• pp.457-468
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• 1993

In oxide matrix-SiC(W) composites, instability and glassy phase formation due to oxidation at the high temperature and the diffusion of Si, respectively, cause brittle fracture and low reliability for ceramic materials. The mode of contribution in each mechanisms induced by matrix-whisker debonding, varies with the morphology of matrix-whisker interfaces. This work has described the dispersion behaviours and stabilization mechanisms in slip systems, and multiple toughening mechanisms by dint of two second phase different from each other when spherical ZrO2 and chemically stable Al2O3(W) is respectively added in Al2O3 matrix. To obtain complexshaped components, slip casted bodies were sintered at 1$600^{\circ}C$, 2hrs up to 98~99% R.D.. Multiple toughening mechanisms in comparison with theories reported until now will be discussed as a result of the phase analysis of ZrO2 by athermal behaviours and microstructural characterizations as well as measured mechanical properties.

• 제어로봇시스템학회논문지
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• 제1권2호
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• pp.78-82
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• 1995

In this paper, we consider the robustness analysis problem in state space models with linear time invariant perturbations. Based upon the discrete-time Lyapunov approach, sufficient conditions are derived for the eigenvalues of perturbed matrix to be located in a circle, and robustness bounds on perturbations are obtained. Spaecially, for the case of a diagonalizable hermitian matrix the bound is given in terms of the nominal matrix without the solution of Lyapunov equation. This robustness analysis takes account not only of stability robustness but also of certain types of performance robustness. For two perturbation classes resulting bounds are shown to be improved over the existing ones. Examples given include comparison of the proposed analysis method with existing one.