• Title/Summary/Keyword: linearity test

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A comparison of Multilayer Perceptron with Logistic Regression for the Risk Factor Analysis of Type 2 Diabetes Mellitus (제2형 당뇨병의 위험인자 분석을 위한 다층 퍼셉트론과 로지스틱 회귀 모델의 비교)

  • 서혜숙;최진욱;이홍규
    • Journal of Biomedical Engineering Research
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    • v.22 no.4
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    • pp.369-375
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    • 2001
  • The statistical regression model is one of the most frequently used clinical analysis methods. It has basic assumption of linearity, additivity and normal distribution of data. However, most of biological data in medical field are nonlinear and unevenly distributed. To overcome the discrepancy between the basic assumption of statistical model and actual biological data, we propose a new analytical method based on artificial neural network. The newly developed multilayer perceptron(MLP) is trained with 120 data set (60 normal, 60 patient). On applying test data, it shows the discrimination power of 0.76. The diabetic risk factors were also identified from the MLP neural network model and the logistic regression model. The signigicant risk factors identified by MLP model were post prandial glucose level(PP2), sex(male), fasting blood sugar(FBS) level, age, SBP, AC and WHR. Those from the regression model are sex(male), PP2, age and FBS. The combined risk factors can be identified using the MLP model. Those are total cholesterol and body weight, which is consistent with the result of other clinical studies. From this experiment we have learned that MLP can be applied to the combined risk factor analysis of biological data which can not be provided by the conventional statistical method.

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Performance Characteristic of the β-Human Chorionic Gonadotropin Assay on the Access 2 for Its Use in Doping Control

  • Kang, Min-Jung;Lee, Hye-Im;Shin, Sang-Mi;Yoo, Hye-Hyun;Kwon, Oh-Seung;Jin, Chang-Bae;Chung, Bong-Chul
    • Bulletin of the Korean Chemical Society
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    • v.31 no.10
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    • pp.2889-2892
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    • 2010
  • The objective of this study was to validate performance characteristics of the Access 2 (Beckman coulter) system for hCG assays for use as a confirmation test for doping control. The Access 2 assay was linear up to 500 IU/L. The correlation coefficient was higher than 0.999, and the sensitivity of the linearity was 0.82. There were no false positive or false negative cases. LOD was 0.59 IU/L. The method was robust when performed by different people. Repeatability and reproducibility were below 7%. We compared reproducibility and recoveries of Access 2 and Elecsys 2010. Access 2 demonstrated higher reproducibility than Elecsys 2010. Recoveries (accuracy) of Access 2 were between 85 and 105%. Recoveries for Elecsys 2010 were between 91 and 104%.

Mornitoring of non-steroidal anti-inflammatory drugs in livestock products (축산식품 중 비스테로이드성 항염증 약물의 잔류함량 모니터링)

  • Choi, Yoon-Hwa;Kim, Yoen-Joo;Shin, Bang-Woo;Lee, Jung-Hark
    • Korean Journal of Veterinary Service
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    • v.34 no.3
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    • pp.285-289
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    • 2011
  • This study was conducted to determine the content of non-steroidal anti-inflammatory drugs (NSAIDs) in meats available on the Korean markets. The analysis was carried out using following conditions; C18 column ($100{\times}2.1$ mm, 1.7 ${\mu}m$), mobile phase composed of DW (containing 0.1% formic acid): acetonitrile (containing 0.1% formic acid), binary pump at a flow rate of 0.3 ml/min and 5 ${\mu}l$ of injection volume, MS/MS detector with ESI positive mode. The calibration range of five NSAIDs showed linearity ($r^2{\geq}0.99$) at concentration range of 3.125~200 ${\mu}g$/kg. The recoveries in fortified muscle more than 78.7~100.3%. The detection limits for meloxicam, ketoprofen, flunixin, carprofen and tolfenamic acid were 3.5, 1.6, 1.7, 9.8 and 4.8 ${\mu}g$/kg, respectively. We also monitored NSAIDs residue in cattle muscle 51 samples. The test results, NSAIDs were all not founded.

A LONG-TERM FIELD TEST OF A LARGE VOLUME IONIZATION CHAMBER BASED AREA RADIATION MONITORING SYSTEM DEVELOPED AT KAERI

  • Kim, Han-Soo;Ha, Jang-Ho;Park, Se-Hwan;Kim, Jung-Bok;Kim, Young-Kyun;Jin, Hyung-Ho
    • Journal of Radiation Protection and Research
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    • v.34 no.2
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    • pp.77-81
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    • 2009
  • An Area Radiation Monitoring System (ARMS) ionization chamber, which had an 11.8 L active volume, was fabricated and performance-tested at KAERI. Low leakage currents, linearities at low and high dose rates were achieved from performance tests. The correlation coefficients between the ionization currents and the dose rates are 1 at high dose rate and 0.99 at low dose rate. In this study, an integration-type ARMS ionization chamber was tested over a year for an evaluation of its long-term stability at a radioisotope (RI) repository of the Young-gwang nuclear power plant. The standard deviation of dose rate of 1 day data and over a 100-days mean value were 6.2 $\mu$R/h and 2.9 $\mu$R/h, respectively. The fabricated ARMS ionization chamber showed stable performance from the results of the long-term tests. Design and performance characteristics of the fabricated ionization chamber for the ARMS from performance-tests are also addressed.

Possibility of Chaotic Motion in the R&D Activities in Korea

  • Loh, Jeunghwee
    • Journal of Information Technology Applications and Management
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    • v.21 no.3
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    • pp.1-17
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    • 2014
  • In this study, various characteristics of R&D related economic variables were studied to analyze complexity of science and technology activities in Korea, as reliance of R&D activities of the private sector is growing by the day. In comparison to other countries, this means that it is likely to be fluctuated by economic conditions. This complexity characteristic signifies that the result of science and technology activities can be greatly different from the anticipated results - depending on the influences from economic conditions and the results of science and technology activities which may be unpredictable. After reviewing the results of 17 variables related to science and technology characteristics of complex systems intended for time-series data - in the total R&D expenditure, and private R&D expenditure, numbers of SCI papers, the existence of chaotic characteristics were. using Lyapunov Exponent, Hurst Exponent, BDS test. This result reveals science and technology activity of the three most important components in Korea which are; heavy dependence on initial condition, the long term memory of time series, and non-linear structure. As stable R&D investment and result are needed in order to maintain steady development of Korea economy, the R&D structure should be less influenced by business cycles and more effective technology development policy for improving human resource development must be set in motion. And to minimize the risk of new technology, the construction of sophisticated technology forecasting system should take into account, for development of R&D system.

A Novel Finite Element Technique for analyzing Saturated Rotating Machines Using the Domain Decomposition and TLM Method (영역분할법 (domain decomposition)과 TLM법을 이용한 회전기의 비선형 유한 요소 해석)

  • Joo, Hyun-Woo;Im, Chang-Hwan;Lee, Chang-Hwan;Kim, Hong-Kyu;Jung, Hyn-Kyo
    • Proceedings of the KIEE Conference
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    • 2000.07b
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    • pp.623-625
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    • 2000
  • For the finite element analysis of highly saturated rotating machines involving rotation of a rotor such as dynamic analysis. cogging torque analysis and etc, so much time is needed because a new system matrix equation should be solved for each iteration and time step. It is proved in this paper that. in linear systems. the computational time can be greatly reduced by using the domain decomposition method (DDM). In nonlinear systems. however. this advantage vanishes because the stiffness matrix changes at each iteration especially when using the Newton-Raphson (NR) method. The transmission line modeling (TLM) method resolves this problem because in TLM method the stiffness matrix does not change throughout the entire analysis. In this paper, a new technique for FEA of rotating machines including rotation of rotor and non-linearity is proposed. This method is applied to a test problem. and compared with the conventional method.

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High Strain-rate Deformation Behavior of NiAl/Ni Micro-laminated Composites (NiAl/Ni 미세적층복합재료의 고속변형거동)

  • Kim Hee-Yeoun;Kim Jin-Young;Jeong Dong-Seok;Enoki Manabu;Hong Soon-Hyung
    • Proceedings of the Korean Society For Composite Materials Conference
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    • 2004.04a
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    • pp.237-240
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    • 2004
  • High strain-rate deformation behavior of NiAl/Ni micro-laminated composites was characterized by split hopkins on pressure bar(SHPB). When the strain rate increased, the compressive stress of micro-laminated composites were increased a little. When the intermetallic volume fraction increased, the compressive stress of micro-laminated composites increased linearly irrespective of strain rate. Absorbed energy during the quasi-static and SHPB tests was calculated from the integrated area of stress-strain curve. Absorbed energy of micro-laminated composites deviated from the linearity in terms of the intermetallic volume fraction but merged to the value of intermetallic as the strain rate increased. This was due to high tendency of intermetallic layer for the localization of shear deformation at high strain rate. Microstructure showing adibatic shear band(ASB) confirmed that the shear strain calculated from the misalignment angle of each layer increased and ASB width decreased when the intermetallic volume fraction. Simulation test impacted by tungsten heavy alloy cylinder resulted that the absorbed energies multiplied by damaged volume of micro-laminated composites were decreased as the intermetallic volume fraction increased. Fracture mode were changed from delamination to single fracture when the intermetallic volume fraction and this results were good matched with previous results[l] obtained from the fracture tests.

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NEW DIGITAL H$\alpha$ OBSERVATION BY SOLAR FLARE TELESCOPE AT BOAO

  • LEE C.-W.;MOON Y.-J.;PARK Y.D.;JANG B.-H.;KIM KAP-SUNG
    • Journal of The Korean Astronomical Society
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    • v.34 no.2
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    • pp.111-117
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    • 2001
  • Recently, we have set up a new digital CCD camera system, MicroMax YHS-1300 manufactured by Roper Scientific for Ha observation by Solar Flare Telescope at Bohyunsan Optical Astronomy Observatory. It has a 12 bit dynamic range, a pixel number of 1300$\times$1030, a thermoelectric cooler, and an electric shutter. Its readout speed is about 3 frames per second and the dark current is about 0.05 e-/p/s at $-10^{\circ}C$. We have made a system performance test by confirming the system linearity, system gain, and system noise that its specification requires. We have also developed a data acquisition software which connects a digital camera con-troller to a PC and acquires H$\alpha$ images via Microsoft Visual C++ 6.0 under Windows 98. Comparisons of high quality H$\alpha$ images of AR 9169 and AR 9283 obtained from SOFT with the corresponding images from Learmonth Solar Observatory in Australia confirm that our H$\alpha$ digital observational system is performed properly. Finally, we present a set of H$\alpha$ images taken from a two ribbon flare occurred in AR 9283.

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An ionization Chamber for a Steel Sheet Thickness Measurement

  • Kim, Han-Soo;Park, Se-Hwa;Kim, Yong-Kyun;Ha, Jang-Ho;Cho, Seung-Yeon
    • Journal of Radiation Protection and Research
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    • v.31 no.3
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    • pp.149-153
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    • 2006
  • An ionization chamber is still widely used in many fields by virtue of its' simple operational characteristics and the possibility of its' various shapes. A parallel type of an ionization chamber for a steel sheet thickness measurement was designed and fabricated. High pure xenon gas, which was pressurized up to 6 atm, was chosen as a filling gas to increase the current response and sensitivity for a radiation. A high pressure gas system was also constructed. The active volume and the incident window size of the fabricated ionization chamber were $30\;cm^3\;and\;12\;cm^2$, respectively. Preliminary tests with a 25 mCi $^{241}Am$ gamma-ray source and evaluation tests in a standard X-ray field were performed. The optimal operation voltage was set from the results of the collection efficiency calculation by using an experimental two-voltage method. Linearity for a variation of the steel sheet thickness, which is the most important factor for an application during a steel sheet thickness measurement, was 0.989 in this study.

Design, Fabrication and Performance Test of A Non-Vacuum Packaged Single Crystalline Silicon MEMS Gyroscope (대기압형 단결정 실리콘 MEMS 각속도계의 설계, 제작 및 성능 측정)

  • Jung, Hyoung-Kyoon;Hwang, Young-Seok;Sung, Woon-Tahk;Chang, Hyun-Kee;Lee, Jang-Gyu;Kim, Yong-Kweon
    • Proceedings of the KIEE Conference
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    • 2006.07c
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    • pp.1635-1636
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    • 2006
  • In this paper, a non-vacuum packaged single crystalline silicon MEMS gyroscope is designed, fabricated and tested. To reduce air damping of the gyroscope structure for non-vacuum packaging, air damping model is used and damping is minimized by analysis. The inner and outer spring length is optimized by ANSYS simulation for rigid body motion. The gyroscope is fabricated by SiOG(Silicon On Glass) process. The performance of the gyroscope is measured to evaluate the characteristic of the gyroscope. The sensitivity, non-linearity, noise density and the bias stability are measured to 9.7693 mV/deg/s, 04265 %, 2.3 mdeg/s/rtHz and 16.1014 deg/s, respectively.

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