한국동물위생학회지 (Korean Journal of Veterinary Service)

  • 제34권3호
  • /
  • Pages.285-289
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  • 2011
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  • 3022-7372(pISSN)
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  • 2287-7630(eISSN)
한국동물위생학회 (The Korean Society of Veterinary Service)
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축산식품 중 비스테로이드성 항염증 약물의 잔류함량 모니터링

Mornitoring of non-steroidal anti-inflammatory drugs in livestock products

  • 최윤화 (서울특별시보건환경연구원) ;
  • 김연주 (서울특별시보건환경연구원) ;
  • 신방우 (서울특별시보건환경연구원) ;
  • 이정학 (서울특별시보건환경연구원)
  • Choi, Yoon-Hwa (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Kim, Yoen-Joo (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Shin, Bang-Woo (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Lee, Jung-Hark (Seoul Metropolitan Government Research Institute of Public Health and Environment)
  • 투고 : 2011.08.08
  • 심사 : 2011.09.10
  • 발행 : 2011.09.30
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초록

This study was conducted to determine the content of non-steroidal anti-inflammatory drugs (NSAIDs) in meats available on the Korean markets. The analysis was carried out using following conditions; C18 column ($100{\times}2.1$ mm, 1.7 ${\mu}m$), mobile phase composed of DW (containing 0.1% formic acid): acetonitrile (containing 0.1% formic acid), binary pump at a flow rate of 0.3 ml/min and 5 ${\mu}l$ of injection volume, MS/MS detector with ESI positive mode. The calibration range of five NSAIDs showed linearity ($r^2{\geq}0.99$) at concentration range of 3.125~200 ${\mu}g$/kg. The recoveries in fortified muscle more than 78.7~100.3%. The detection limits for meloxicam, ketoprofen, flunixin, carprofen and tolfenamic acid were 3.5, 1.6, 1.7, 9.8 and 4.8 ${\mu}g$/kg, respectively. We also monitored NSAIDs residue in cattle muscle 51 samples. The test results, NSAIDs were all not founded.

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참고문헌

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