• 한국항공우주학회지
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• 제33권4호
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• pp.79-84
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• 2005

평판 표면에 충돌하는 축대칭, 과소팽창 제트에 대한 실험적 연구가 수행되어졌으며, 벽압력 및 단열 벽온도 분포가 자세히 측정되어졌다. 벽온도 분포 결과에 대한 설명을 위하여 자유제트 내에서의 전온도 값을 전온도 탐침을 사용하여 측정하였다. 본 연구에서 실험 변수로는 과소팽창비와 노즐-평판간 거리가 고려되었다. 노즐-평판 간 거리에 따라 제트 경계 및 충돌면에서의 에너지 박리에 의해 서로 다른 형태의 단열 벽온도 분포가 나타났으며, 과소팽창비가 큰 경우, 중심영역에서의 저온 유체 입자의 고립효과로 정체점의 회복계수가 크게 낮아지는 현상 또한 관찰되었다.

• 한국재난정보학회 논문집
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• 제14권2호
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• pp.107-114
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• 2018

연구목적 : 본 연구는 전통시장의 화재확산 방지를 위해 지붕 위에 적용한 벽면녹화 기술을 활용한 벽체개발이다. 연구방법 : 개발한 벽면에서 설치된 살수헤드는 평상시에 식물을 위해 사용하다가 화재발생시 인접 건물로 화재가 확산되지 않도록 할 수 있도록 살수배관 겸용 사용이 가능하도록 설계하였다. 또한, 벽면에 식재된 식물의 생장을 위하여 최 상층부 및 일부 구간에 살수헤드를 부착하여 필요시 살수 할 수 있는 시스템을 구축하였으며, 화재발생과 같은 유사시에 보다 많은 양의 물을 살수하여 화재확산방지효과를 극대화 할 수 있도록 설계하여 객관성을 입증하고자 하였다. 연구결과 : 이러한 기술을 통해 전통시장과 같이 밀접건물 상층부에 설치 가능한 벽체개발을 제안하였으며, 구조물과 스프링클러와의 일체형으로 별도의 차단설비가 불필요하게 설계하였다. 그리고 스프링클러가 식물의 살수와 화재확산방지 기능을 동시에 수행이 가능하다. 이는 국내에서 유일하게 제안한 화재확산방지용 대안기술이라 판단된다. 결론 : 본 연구에서는 화재확산 저감효과의 정량화 성능 도출을 위해 직접 디자인한 벽체설계를 통해 벽면시스템의 화재진압 방법, 그리고 벽면자체의 내구성 및 난연성능을 검증하였다.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 춘계학술대회논문집
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• pp.383-386
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• 2005

Low frequency heavy-weight impact noise is the most irritating noise in Korean high-rise reinforced concrete apartment buildings. This low frequency noise is generated by foot traffic due to the fact that Koreans do not wear shoes at home. The transmission of the noise is facilitated by a load bearing wall structural system without beams and columns which is used in these buildings. In order to control low frequency heavy-weight impact noise, floating floors using isolation materials such as glass-wool mat and poly-urethane mat are used. However, it was difficult to control low frequency heavy-weight impact sound using isolation material. In this study, reinforcement of concrete slab using beams and plate was conducted. Using the FEM analysis, the effect of concrete slab reinforcement using FRP(fiber-glass reinforced plastic) on the bang machine impact vibration acceleration level and sound were conducted at the standard floor impact sound test building. The $3{\sim}4dB$ floor impact vibration acceleration level and impact sound pressure level were reduced and the natural frequency of slabs were changed.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2004년도 춘계학술대회논문집
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• pp.308-311
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• 2004

It is reported that there is a limit in increasing heavy-weight impact noise isolation performance of the load bearing wall system apartments to meet the regulation of the Ministry of Construction and Transportation (MOCT). To increase the heavy-weight impact noise isolation performance, improvement in structural systems such as increasing concrete slab thickness and application of rahmen structure were proposed. In this study floor impact sound levels from toil apartments with two rahmen structure multi-story residential buildings were measured before the construction of the buildings finished. Measurements were made at living room and two bedrooms at each apartment when the finishing processes were finished. The average value of light-weight impact sound level from ten apartments was 56dB (L'$\sub$n,Aw/). The heavy-weight impact sound level was 44dB (L'$\sub$i.Fmax.Aw/) and the impact sound level of the impact ball was 41dB(L'$\sub$i.Fmax.Aw/), As a result floor impact noises at the rahmen structure system were lower than the regulation level.

• Journal of Plant Biotechnology
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• 제42권2호
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• pp.93-103
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• 2015

The isolation, cloning, and characterization of an R2R3-MYB transcription factor gene (MtMYB70) from the model legume Medicago truncatula is reported. MtMYB70 consists of a 768-bp coding sequence corresponding to 255 amino acids. Sequence alignment revealed that MtMYB70 cDNA contains conserved R2R3-type MYB domains with highly divergent C terminal regions. MtMYB70 was found to have relatively low sequence homology with known R2R3-MYB genes. Phylogenetic analysis placed the R2R3-MYB domain of MtMYB70 closest to PtMYB1, a known activator of lignin biosynthesis. Overexpression of MtMYB70 under the control of the 35S promoter in transgenic poplar did not cause a significant difference in total lignin content relative to the control, but glucan content was significantly increased in transgenic poplar. Therefore, MtMYB70 might have regulatory role in the biosynthesis of cell wall structural carbohydrates.

• Food Science and Biotechnology
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• 제15권6호
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• pp.877-883
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• 2006

The immunostimulatory activities of Lactobacillus plantarum, the major microorganism in kimchi fermentations were investigated. Five strains of L. plantarum exhibited weak immunopotentiating activity, but L. plantarum PS-21 showed as strong a mitogenic activity as Bifidobacterium adolescentis M101-4, a known positive strain. It is of interest that, L. plantarum PS-21 stimulated proliferation of Peyer's patch cells, one of the most important tissues in the gut-associated lymphoreticular system. Cell' wall fractions from L. plantarum PS-21 also showed strong mitogenic activity compared with the soluble cytoplasmic fraction. A peptidoglycan fraction (PG) extracted from the cell wall of L. plantarum PS-21 was identified as an active mitogenic component when used in murine lymph node and spleen cell test systems. PG showed dose-dependent mitogenic activity and significantly enhanced antibody production in lymph node cells when studied in vitro. The lysosomal enzyme activity of murine peritoneal macrophages was increased when analyzed following injection of PG to the host animal. Furthermore, PG enhanced the production of cytokines such ($TNF-{\alpha}$ and IL-6) in the in vitro culture of RAW 264.7 macrophage cells.

• 한국미생물·생명공학회지
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• 제24권1호
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• pp.27-36
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• 1996

The aim of the present research program was to identify and develop strains of actinomycetes producing antifungal antibiotics which inhibit cell wall biosynthesis. 860 strains of Actinomycetes were isolated from various soil samples. Three isolates, EMS4, EMP22, and L234 were selected as the strains producing antifungal antibiotics inducing abnormal morphology against Penicillium cyclopium, Cryptococcus laurentii, and Aspergillus flavus, respectively. Taxonomic unit characters of the strains were tested and the data were analyzed numerically using TAXON program. EMS4, EMP22, and L234 were indentified to be a member of Streptomyces lavendulae, Streptomyces willmorei, and Streptomyces aburaviensis, respectively.

• 약학회지
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• 제52권6호
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• pp.494-499
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• 2008

The role of antibody in the fungal infections is controversial. However, our previous reports showed a certain epitope in Candida albicans cell wall (CACW) induces protective antibody. A major problem is that the epitope isolation requires tremendous time with high cost. This aspect led us to investigate a simple way inducing protective antibodies against C. albicans. In the present study, we determined if $18{\beta}$-glycyrrhetinic acid ($18{\beta}$-GA) from Glabrae Radix (a family of Leguminosae) has immunoadjuvant activity. Data displayed that the $18{\beta}$-GA suppressed proliferations of both T- and Blymphocytes at high concentrations, whereas below 20 ${\mu}M$ concentration the compound supported the proliferations. These observations indicate that $18{\beta}$-GA has immunoregulatory activity. Based on this observation, an immunoadjuvant effect was examined at the low concentration. Results from animal experiments showed that CACW combined with or without $18{\beta}$-GA produced the anti-C. albicans antiserum in mice. Nevertheless, the CACW combined with $18{\beta}$-GA formula only protected mice against disseminated candidiasis (P<0.05). These data implicate that $18{\beta}$-GA has immunoadjuvant activity, which may provoke the CACW antigen to induce protective antibody. Currently, we are investigating possible mechanism of how the $18{\beta}$-GA provokes such protective immunity against the disseminated disease.

• Archives of Pharmacal Research
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• 제14권4호
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• pp.298-304
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• 1991

Isoprinosine, an antiviral agent with a bitter taste, has been clinically used up to a maximum of 4 g daily in 4-8 doses. In this investigation, isoprinosine was microencapsulated with ethylcellulose 22 cps, 50 cps and 100 cps by means of polymer deposition from cyclohexane through temperature change. Complete removal of cyclohexane from the microcapsules was necessary, since ethylcellulose-coated microcapsules obtained from cyclohexane medium were heavily solvated with cyclohexane and formed lumps even after drying. The displacement of cyclohexane by n-hexane during isolation of microcapsules (Method III) or the freezing of the anal-washed microcapsules before drying (Mothod II) provided the dried products which were more discrete microcapsules than those which were simply dried in the air overnight (Method I). Method III was especially the most effective procedure in preparing finer and more discrete microcapsules. The drug-release from microcapsules was influenced by the ratio of core to wall, the viscosity grade of ethylcellulose and the overall microcapsule size. The release rate was adequately fitted to both the first-order and the diffusion-controlled processes. It is therefore possible to design the release-controlled microcapsules with ethylcellulose of different viscosity along with various core to wall ratio.

• Restorative Dentistry and Endodontics
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• 제6권1호
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• pp.93-103
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• 1980

Streptococcus mutans were isolated from dental plaques of carious lesions of 4 patients on mitis-salivarius agar medium. Three patients known to harbor S. mutans in their dental plaques. Identification of the isolated S. mutans was established by colonial morphology on mitis-salivarius agar medium, the fermentation of mannitol and sorbitol, and confirmed by agglutinating reaction with home made anti-S. mutans NCTC 10449 (serotype c) antiserum. Of the isolated S. mutans, one strain (P2-1) showed strong agglutinating reaction with antiserum, another strain (P1-2) showed weak agglutinating reaction. P2-1 strongly adhered to the wall of the test tube containing 5% sucrose broth, while p1-2 weakly colonized on the wall of the test tube. Biotyping of the isolated S. mutans based on the fermentation of mannitol, sorbitol, raffinose and melibiose, and the production of ammonia from L-arginine, and the inhibition of acid production by bacitracin. Biochemical characteristics of P2-1 strain correlated with the recognized biotype c, pl-2 strain resembled biotype d of S. mutans.