Isolation and Numerical Identification of Streptomyces Strains Producing Inhibitors of Fungal Cell Wall Synthesis

진균 세포벽 형성 저해물질 생성 Streptomyces속 세균의 분리 및 수리동정

  • Suh, Won-Na (Department of Biological Science, College of Natural Science, Ewha Womans University) ;
  • Park, Jung-Hee (Department of Biological Science, College of Natural Science, Ewha Womans University) ;
  • Lee, Ji-Young (Department of Biological Science, College of Natural Science, Ewha Womans University) ;
  • Kim, In-Seop (Department of Microbiology and Research Center for Molecular Microbiology, Seoul National University) ;
  • Lee, Kye-Joon (Department of Microbiology and Research Center for Molecular Microbiology, Seoul National University) ;
  • Bae, Moo (Department of Biological Science, College of Natural Science, Ewha Womans University)
  • 서원나 (이화여자대학교 자연과학대학 생물과학과) ;
  • 박정희 (이화여자대학교 자연과학대학 생물과학과) ;
  • 이지영 (이화여자대학교 자연과학대학 생물과학과) ;
  • 김인섭 (서울대학교 미생물학과) ;
  • 이계준 (서울대학교 미생물학과) ;
  • 배 무 (이화여자대학교 자연과학대학 생물과학과)
  • Published : 1996.02.01

Abstract

The aim of the present research program was to identify and develop strains of actinomycetes producing antifungal antibiotics which inhibit cell wall biosynthesis. 860 strains of Actinomycetes were isolated from various soil samples. Three isolates, EMS4, EMP22, and L234 were selected as the strains producing antifungal antibiotics inducing abnormal morphology against Penicillium cyclopium, Cryptococcus laurentii, and Aspergillus flavus, respectively. Taxonomic unit characters of the strains were tested and the data were analyzed numerically using TAXON program. EMS4, EMP22, and L234 were indentified to be a member of Streptomyces lavendulae, Streptomyces willmorei, and Streptomyces aburaviensis, respectively.

Keywords