• Title/Summary/Keyword: integrated science

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Analysis of Case Studies of Treating Atopic Dermatitis - focusing on Korean Herbal Medicine Used in Cases - (아토피 피부염 증례 연구 분석 - 한약 처방을 중심으로 -)

  • Han, Chang-Yi;Park, Jung-Gun;Kang, Dong-Won;Park, So-Young;Kim, Bong-Hyun;Kim, Yoon-Bum;Kim, Kyu-Seok
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.3
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    • pp.151-163
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    • 2019
  • Objectives : The purpose of this study is to investigate the use of herbal medicine for the treatment of atopic dermatitis in cases and to find the general tendency of herbal medicine treatment and to establish the primary treatment direction of Atopic dermatitis. Methods : In the domestic databases, Oriental medicine Advanced Searching Integrated System(OASIS), Korean Traditional Knowledge Portal(KTKP), National Discovery for Science Leader(NDSL), Research Information Sharing Service(RISS), we selected among the papers published in the last 20 years using search terms related to "Atopic dermatitis & Cases". Reports based on Sasang constitutional medicine and Six meridian pattern identification were excluded and a total of 21 papers were finally selected. Results : 113 herbal medicines were retrieved from 21 papers. The most commonly used herbs are Scutellariae Radix(黃芩), Rehmanniae Radix(地黃), and Glycyrrhizae Radix et Rhizoma(甘草). Atractylodis Rhizoma(蒼朮), Akebiae Caulis(木通), Smilacis Rhizoma(土茯?), Paeoniae Radix(芍藥) used mostly when Oozing exists, Trichosanthis Radix (瓜蔞), Asparagi Radix(天門冬), Persicae Semen(桃仁), Carthami Flos(紅花) used mostly when Dryness, Lichenification, and Pigmentation exist. The average score of SCORAD index was improved after Herbal medicine treatment. Conclusion : Through this study, we could find out the tendency of herbal medicine to treat Atopic dermatitis along with Symptoms.

Nitric Oxide Delivery using Nanostructures and Its Biomedical Applications (나노 구조체를 이용한 산화질소 전달체에 대한 연구 및 바이오메디컬 응용)

  • Choi, Yunseo;Jeong, Hyejoong;Park, Kyungtae;Hong, Jinkee
    • Korean Chemical Engineering Research
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    • v.57 no.3
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    • pp.305-312
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    • 2019
  • The discovery of nitric oxide (NO) as a major signaling molecule in a number of pathophysiological processes - vasodilation, immune response, platelet aggregation, wound repair, and cancer biology - has led to the development of various exogeneous NO delivery systems. However, the development of ideal delivery system for human body application is still left as a challenge due to its high reactivity and short half-life in physiological condition. In this article, an overview of several nano-structures as potential NO delivery system will be presented, along with their recent research results and biomedical applications. Nano-size delivery system has immense advantages compared to others due to its high surface-to-volume ratio and capability for surface modification; thus, it has been proven to be effective in delivering nitric oxide with enhanced performance. Through this novel nano-structure delivery system, we are expecting to achieve sustained release of nitric oxide within adequate range of concentration, which ensures desired drug effects at the target site. Among different nano-structures, in particular, nanoparticle, microemulsion and nanofilm will be reviewed and compared to each other in respect of nitric oxide release profile. The proposed nano-structures for exogeneous NO delivery have a biological significance in that it can be further utilized in diverse biomedical fields as a highly promising therapeutic method.

Dredging Material Application Lightweight Foamed Soil Full Scale Test Bed Verification (준설토 활용 경량기포혼합토 실규모 현장 실증 연구)

  • Kim, Dong-Chule;Yea, Gue-Guwen;Kim, Hong-Yeon;Kim, Sun-Bin;Choi, Han-Lim
    • Journal of Coastal Disaster Prevention
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    • v.5 no.4
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    • pp.163-172
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    • 2018
  • To propose the design technique and the execution manual of the LWFS(Lightweight Foamed Soil) method using dredged soil, the operation system for the test-bed integrated management, and to establish an amendment for the domestic quantity per unit and specifications, and a strategy for its internationalization. In order to utilize the dredged soil from the coastal area as a construction material, we constructed the embankment with LWFS on soft ground and monitored its behavior. As a result, it can be expected that the use of LWFS as an embankment material on the soft ground can improve the economic efficiency by reducing the depth and period of soil improvement as well as the uses of nearby dredged soil. To verify the utilization of the dredged soil as a material for light-weighted roadbed, soft ground and foundation ground, and surface processing, perform an experimental construction for practical structures and analyze the behavior. It is expected to be able to improve the soft ground with dredged soil and develop technique codes and manuals of the dredged soil reclamation by constructing a test-bed in the same size of the fields, and establish the criteria and manual of effective dredged soil reclamation for practical use. The application technology of the dredged soil reclamation during harbor constructions and dredged soil reclamation constructions can be reflected during the working design stage. By using the materials immediately that occur from the reclamation during harbor and background land developments, the development time will decrease and an increase of economic feasibility will happen. It is expected to be able to apply the improved soil at dredged soil reclamation, harbor and shore protection construction, dredged soil purification projects etc. Future-work for develop the design criteria and guideline for the technology of field application of dredged soil reclamation is that review the proposed test-bed sites, consult with the institutions relevant with the test-bed, establish the space planning of the test-bed, licensing from the institutions relevant with the test-bed, select a test-bed for the dredged soil disposal area.

Characteristics of the spatio-temporal distributions of water quality and phytoplankton communities in the Isa Stream systems (ISS) (이사천 수계의 수질환경과 식물플랑크톤 군집의 시·공간적 분포 특성)

  • Park, Jong Sick;Cheong, Cheong-Jo;Yoon, Yang Ho
    • Korean Journal of Environmental Biology
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    • v.39 no.3
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    • pp.273-288
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    • 2021
  • We analyzed the spatio-temporal distribution characteristics of water quality and phytoplankton communities in the Isa Stream systems (ISS) from Sangsa Lake to Suncheon Bay. Sangsa Lake showed relatively oligotrophic and mesotrophic conditions, but the freshwater and mixed brackish water zones showed more severe eutrophication than Sangsa Lake and Suncheon Bay due to the influence of industrial waste such as livestock waste. In terms of the phytoplankton community, the number of phytoplankton species was higher in freshwater and mixed brackish water zones than in Sangsa Lake and Suncheon Bay, but the cell density and Chlorophyll-a concentrations (Chl-a) were relatively high in Sanga Lake and Suncheon Bay. In particular, the mesotrophic species Fragilaria crotonensis and Asterionella formosa showed different dominance in the surface and bottom layers, and the influence of A. formosa was significant in the freshwater and mixed brackish water zones in spring and summer. However, Skeletonema costatum-ls, a eutrophic indicator species, dominated in mixed brackish water zones to seawater in autumn and winter. Thus, the severe eutrophication and rapid environmental changes in the ISS could seriously damage the coastal ecosystem in Suncheon Bay. These ecosystem changes are threatening in terms of conservation and management of the UNESCO Suncheon Biosphere Reserve and Yeoja Bay including Suncheon Bay, which recorded the first Ramsar wetland in Korea. Therefore, further research is needed to establish an in-depth management plan.

Conceptual eco-hydrological model reflecting the interaction of climate-soil-vegetation-groundwater table in humid regions (습윤 지역의 기후-토양-식생-지하수위 상호작용을 반영한 개념적인 생태 수문 모형)

  • Choi, Jeonghyeon;Kim, Sangdan
    • Journal of Korea Water Resources Association
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    • v.54 no.9
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    • pp.681-692
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    • 2021
  • Vegetation processes have a significant impact on rainfall runoff processes through evapotranspiration control, but are rarely considered in the conceptual lumped hydrological model. This study evaluated the model performance of the Hapcheon Dam watershed by integrating the ecological module expressing the leaf area index data sensed remotely from the satellite into the hydrological partition module. The proposed eco-hydrological model has three main features to better represent the eco-hydrological process in humid regions. 1) The growth rate of vegetation is constrained by water shortage stress in the watershed. 2) The maximum growth of vegetation is limited by the energy of the watershed climate. 3) The interaction of vegetation and aquifers is reflected. The proposed model simultaneously simulates hydrologic components and vegetation dynamics of watershed scale. The following findings were found from the validation results using the model parameters estimated by the SCEM algorithm. 1) Estimating the parameters of the eco-hydrological model using the leaf area index and streamflow data can predict the streamflow with similar accuracy and robustness to the hydrological model without the ecological module. 2) Using the remotely sensed leaf area index without filtering as input data is not helpful in estimating streamflow. 3) The integrated eco-hydrological model can provide an excellent estimate of the seasonal variability of the leaf area index.

Therapeutic Intervention to Reduce Spasticity (경련성 감소를 위한 치료적 중재 연구)

  • Lee, Jung-Ho
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.5
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    • pp.427-436
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    • 2019
  • This study investigated the effect of extracorporeal shock wave therapy on the knee angle, MAS, and TUG of the affected side in patients with hemiplegic strokes. This study selected 20 patients who received rehabilitation treatment at a hospital after having been diagnosed with stroke. The control group (n=10) received the general physiotherapy (proprioceptive neuromuscular facilitation), and the experimental group (n=10) applied the extracorporeal shock wave therapy (ESWT) to the injured limb after PNF treatment. This study used an integrated kinematics analyzer (4D-MT, Relive, Korea) to analyze walking, timed up and go test to evaluate the dynamic balance ability of patients, and MAS to evaluate the spasticity. In the study results, knee angle were significantly different in all groups(p<0.05) but there was no significant difference between the groups(p>0.05). In the study results, TUG were significantly different in all groups(p<0.05) but there was no significant difference between the groups(p>0.05). Based on the results of this study, I hope that more detailed research will proceed.

A Study on the Land-Use Related Assessment Factors in Korean Environmental Impact Assessment (환경영향평가 토지환경 분야의 토지이용 평가항목 고찰 연구)

  • Park, Sang-Jin;Lee, Dong Kun;Jeong, Seulgi
    • Journal of Environmental Impact Assessment
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    • v.30 no.5
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    • pp.297-304
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    • 2021
  • The environmental impact assessment(EIA) project in Korea has undergone changes and revisions in various evaluation items for about 30 years after the introduction of the Environmental Conservation Act (1997). However, despite the importance of land use evaluation items under the current EIA Act, there are insufficient studies to consider. Therefore, this study focused on the land-use evaluation items based on the EIA guidelines, reviewed 90 of the evaluation documents and consultation documents, and tried to suggest implications and supplementary points forthe domestic EIA land-use evaluation items. As a result, the paradigm was changing from land efficiency centered on development in the past to land efficiency centered on the natural environment and resource conservation. However, in spite of the manual for fitting the paradigm change, opinions on the conservation of the natural environment are still being drawn in the consultation document, so it needs improvement. Two improvements in the impact assessment process suggested in this study are the establishment of standardized spatial data and a quantitative impact and reduction method evaluation tool based on it. In particular, there is a need for a plan evaluation tool for land use arrangement and distribution that can solve the needs of minimizing damage to the natural environment and securing green space and a green network.

Pollution characteristics of PM2.5 observed during January 2018 in Gwangju (광주 지역에서 2018년 1월 측정한 초미세먼지의 오염 특성)

  • Yu, Geun-Hye;Park, Seung-Shik;Jung, Sun A;Jo, Mi Ra;Jang, Yu Woon;Lim, Yong Jae;Ghim, Young Sung
    • Particle and aerosol research
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    • v.15 no.3
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    • pp.91-104
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    • 2019
  • In this study, hourly measurements of $PM_{2.5}$ and its major chemical constituents such as organic and elemental carbon (OC and EC), and ionic species were made between January 15 and February 10, 2018 at the air pollution intensive monitering station in Gwangju. In addition, 24-hr integrated $PM_{2.5}$ samples were collected at the same site and analyzed for OC, EC, water-soluble OC (WSOC), humic-like substance (HULIS), and ionic species. Over the whole study period, the organic aerosols (=$1.6{\times}OC$) and $NO_3{^-}$ concentrations contributed 26.6% and 21.0% to $PM_{2.5}$, respectively. OC and EC concentrations were mainly attributed to traffic emissions with some contribution from biomass burning emissions. Moreover, strong correlations of OC with WSOC, HULIS, and $NO_3{^-}$ suggest that some of the organic aerosols were likely formed through atmospheric oxidation processes of hydrocarbon compounds from traffic emissions. For the period between January 18 and 22 when $PM_{2.5}$ pollution episode occurred, concentrations of three secondary ionic species ($=SO{_4}^{2-}+NO_3{^-}+NH_4{^+}$) and organic matter contributed on average 50.8 and 20.1% of $PM_{2.5}$, respectively, with the highest contribution from $NO_3{^-}$. Synoptic charts, air mass backward trajectories, and local meteorological conditions supported that high $PM_{2.5}$ pollution was resulted from long-range transport of haze particles lingering over northeastern China, accumulation of local emissions, and local production of secondary aerosols. During the $PM_{2.5}$ pollution episode, enhanced $SO{_4}^{2-}$ was more due to the long-range transport of aerosol particles from China rather than local secondary production from $SO_2$. Increasing rate in $NO_3{^-}$ was substantially greater than $NO_2$ and $SO{_4}^{2-}$ increasing rates, suggesting that the increased concentration of $NO_3{^-}$ during the pollution episode was attributed to enhanced formation of local $NO_3{^-}$ through heterogenous reactions of $NO_2$, rather than impact by long-range transportation from China.

An Exploration of Learning Environment for Promoting Conceptual Understanding, Immersion and Situational Interest in Small Group Learning Using Augmented Reality (증강현실을 활용한 소집단 학습에서 개념 이해 및 몰입, 상황 흥미를 촉진할 수 있는 학습 환경 탐색)

  • Shin, Seokjin;Noh, Taehee;Lee, Jaewon
    • Journal of the Korean Chemical Society
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    • v.64 no.6
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    • pp.360-370
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    • 2020
  • This study explored the learning environment for promoting conceptual understanding, immersion, and situational interest in small group learning using augmented reality, according to the level of students' self-regulation. 95 ninth-grade students from a coed high school in Seoul participated in this study. Students were divided into a group of four and each group was randomly assigned to three learning environments that provide one marker and one smart device(1-1), two markers and two smart devices(2-2), and four markers and four smart devices(4-4) for a group. Small group learning using augmented reality was conducted for two class periods about the chemical bonding concept from the Integrated Science subject. Two-way ANOVA results revealed that students in the 4-4 learning environment scored significantly higher than those in the 1-1 or 2-2 learning environment in a conception test. Changes in the learning environment have affected students with a low level of self-regulation. In an immersion test, students in the 4-4 learning environment scored significantly higher than those in the 1-1 learning environment, and changes in the learning environment have affected students with a high level of self-regulation. As a result of situational interest test, students in the 4-4 and 2-2 learning environments scored significantly higher than those in the 1-1 learning environment, and changes in the learning environment have affected students with a low and a high level of self-regulation. Based on the results, the educational implications of the learning environment for promoting conceptual understanding, immersion, and situational interest in small group learning using augmented reality are discussed.

A Study on the Trends of Korean Juvenile Gambling (청소년 도박의 국내 연구동향 분석)

  • Ko, Do-Hyun;Kim, Sang-Mi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.1
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    • pp.660-671
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    • 2021
  • This paper analyzed the research trends of juvenile gambling, which is increasing due to recent changes in the internet environment. The number of domestic studies on juvenile gambling has increased, but there are few studies that analyzed both degrees and academic papers in a more comprehensive manner than addiction to the Internet, games, and drugs related to youth. The current state of juvenile gambling can lead to secondary crimes, such as illegal loans and thefts for gambling funds beyond the level of addiction, school violence and money extortion, which have been a major shock to Korean society. Therefore, it is urgent to prepare social measures because the age of adolescents who are exposed to gambling is becoming lower. Accordingly, this study analyzed 52 dissertations, 86 academic papers, and three other research reports published in Korea from 2003 to March 2020. As a result, quantitative research, research subjects, and research topics were concentrated, and there was a limit to generalization. In addition, these results will provide rich information to future studies by confirming the academic characteristics according to the times and interdisciplinary research trends that transcend individual science areas.