• The Korean Journal of Physiology and Pharmacology
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• v.20 no.1
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• pp.35-39
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• 2016

To conduct a kinetic study of paraquat (PQ), we investigated 9 patients with acute PQ intoxication. All of them ingested more than 20 ml of undiluted PQ herbicide to commit suicide and arrived at our hospital early, not later than 7 h after PQ ingestion. The urine dithionite test for PQ in all of the nine patients was strongly positive at emergency room. Blood samples were obtained every 30 min for the first 2~3 h and then every 1 or 2 h, as long as the clinical progression was stable among the patients for 30 h after PQ ingestion. The area under the plasma concentration-time curve ($AUC_{inf}$), which was extrapolated to infinity, was calculated using the trapezoidal rule. Toxicokinetic parameters, such as the terminal elimination half-life, apparent oral clearance, and apparent volume of distribution ($V_d/F$) were calculated. The maximum PQ concentration ($C_{max}$) and the time to reach maximum PQ concentration ($T_{max}$) were also obtained. Plasma PQ concentrations in nine patients were well described by a bi-exponential curve with a mean terminal elimination half-life of $13.1{\pm}6.8h$. $C_{max}$ and $AUC_{inf}$ were $20.8{\pm}25.7mg/l$ and $172.5{\pm}160.3h{\cdot}mg/l$, respectively. Apparent volume of distribution and apparent oral clearance were $50.9{\pm}61.3l/kg$ and $173.4{\pm}111.2l/h$, respectively. There were a significant correlation (r=0.84; p<0.05) between the PQ amount ingested and $C_{max}$. $AUC_{inf}$ also showed a significant correlation (r=0.83; p<0.05) with the PQ amount ingested. These correlations provide evidence that PQ has dose-linear toxicokinetic characteristics.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.04a
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• pp.635-639
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• 1997

In order to design a system a process or plant must be put into a mathematical form for analysis and evaluation, and an appropriate controller must be designed to attain the desired system response. In this paper, the mathematical model for an optical pickup actuator is proposed and an H .inf. controller is employed to obtain the optimal focusing/tracking servo system behavior. Simulation and experiments are carried out to verify the performance of the proposed model.

• Bulletin of the Korean Mathematical Society
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• v.27 no.2
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• pp.157-164
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• 1990

The purpose of this paper is to consider the inhomogeneous initial value problem (Fig.) in a Banach space X, where Z is the generator of an exponentially bounded C-semigroup in X, f9t) : [0, T].rarw.X and x.mem.X. Davies-Pang [1] showed the corresponding homogeneous equation, this is, the equation with f(t).iden.0, has a unique solution depending continuoously on the initial value x.mem.CD(z) in the $C^{-1}$-graph norm on CD(Z) when T=.inf..

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.5
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• pp.27-34
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• 1998

This paper is on the discrete model reduction method over disc-type analytic domains. We define hankel singular value over the disc that is mapped by standard bilinear mapping. And the generalized singular perturbation approximation and the direct truncation are generalized to GSPA and DT over a disc. Furthermore, it is shown that the reduced order model over a smaller domaing has a smaller .inf.-norm error bound. And the poposed reduction method is used to obtain the regional pole placement property.

• Kyungpook Mathematical Journal
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• v.53 no.3
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• pp.333-340
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• 2013

In this paper, we prove that on a K$\ddot{a}$hler spin foliatoin of codimension $q=2n$, any eigenvalue ${\lambda}$ of type $r(r{\in}\{1,{\cdots},[\frac{n+1}{2}]\})$ of the basic Dirac operator $D_b$ satisfies the inequality ${\lambda}^2{\geq}\frac{r}{4r-2}\;{\inf}_M{\sigma}^{\nabla}$, where ${\sigma}^{\nabla}$ is the transversal scalar curvature of $\mathcal{F}$.

• Bulletin of the Korean Mathematical Society
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• v.31 no.1
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• pp.45-54
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• 1994

Throughout this paper, the definitions and properities related to probabilistic normed spaces are followed as in [2]. Let R be the set of all real numbers. A mapping F:R .rarw. [0, 1] is called a distribution function on R if it is nondecreasing and left continuous with inf F = 0 and sup F = 1. We denote by L the set of all distribution functions on R.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.1456-1459
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• 1997

In this paper, a control system using robust H.inf. controller based on convex parametrization is presented for nonlinear system with uncertainty. accounting for the time delay, noise and linearization error by frequency analysis, the suboptmal controller is designed to meet robust stability and performance for uncertainty. The desinged control system is applied to a nonlimear boiler moderl to test its performances.

• Bulletin of the Korean Mathematical Society
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• v.51 no.3
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• pp.653-657
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• 2014

Let R be a commutative Noetherian ring, I and J two ideals of R, and M a finitely generated R-module. We prove that $$Ext^i{_R}(R/I,H^t{_{I,J}}(M))$$ is finitely generated for i = 0, 1 where t=inf{$i{\in}\mathbb{N}_0:H^2{_{I,J}}(M)$ is not finitely generated}. Also, we prove that $H^i{_{I+J}}(H^t{_{I,J}}(M))$ is Artinian when dim(R/I + J) = 0 and i = 0, 1.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10b
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• pp.565-568
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• 1996

In this paper, a solution method is proposed to calculate the optimum solution to discrete optimal H$_{.inf}$ control problem for feedback of linear time-invariant system states and disturbance variable. From the results of this study, condition of existence and uniqueness of its solution is that transfer matrix of controlled variable to input variable is left invertible and has no invariant zeros on the unit circle of the z-domain as well as extra geometric conditions given in this paper. Through a numerical example, the noniterative solution method proposed in this paper is illustrated.

• 제어로봇시스템학회:학술대회논문집
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• 1989.10a
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• pp.947-951
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• 1989

A Class of nonlinear distributed parameter control problems is first stated in a partial differential equation form in multi-index notion and then converted into an integral equation form. Necessary conditions for optimality in the form of maximum principle are then derived in Sobolev space W$^{l}$, p/(1 leq. p .leq. .inf.)..