Kwon, Chiheon;Kang, Koung Mi;Byun, Min Soo;Yi, Dahyun;Song, Huijin;Lee, Ji Ye;Hwang, Inpyeong;Yoo, Roh-Eul;Yun, Tae Jin;Choi, Seung Hong;Kim, Ji-hoon;Sohn, Chul-Ho;Lee, Dong Young
Investigative Magnetic Resonance Imaging
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v.25
no.3
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pp.164-171
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2021
Purpose: Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Brain atrophy in this disease spectrum begins in the medial temporal lobe structure, which can be recognized by magnetic resonance imaging. To overcome the unsatisfactory inter-observer reliability of visual evaluation, quantitative brain volumetry has been developed and widely investigated for the diagnosis of MCI and AD. The aim of this study was to assess the prediction accuracy of quantitative brain volumetry using a fully automated segmentation software package, NeuroQuant®, for the diagnosis of MCI. Materials and Methods: A total of 418 subjects from the Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer's Disease cohort were included in our study. Each participant was allocated to either a cognitively normal old group (n = 285) or an MCI group (n = 133). Brain volumetric data were obtained from T1-weighted images using the NeuroQuant software package. Logistic regression and receiver operating characteristic (ROC) curve analyses were performed to investigate relevant brain regions and their prediction accuracies. Results: Multivariate logistic regression analysis revealed that normative percentiles of the hippocampus (P < 0.001), amygdala (P = 0.003), frontal lobe (P = 0.049), medial parietal lobe (P = 0.023), and third ventricle (P = 0.012) were independent predictive factors for MCI. In ROC analysis, normative percentiles of the hippocampus and amygdala showed fair accuracies in the diagnosis of MCI (area under the curve: 0.739 and 0.727, respectively). Conclusion: Normative percentiles of the hippocampus and amygdala provided by the fully automated segmentation software could be used for screening MCI with a reasonable post-processing time. This information might help us interpret structural MRI in patients with cognitive impairment.
Purpose: To obtain regional blood flow and tissue-blood partition coefficient with time-activity curves from ${H_2}^{15}O$ PET, fitting of some parameters in the Kety model is conventionally accomplished by nonlinear least squares (NLS) analysis. However, NLS requires considerable compuation time then is impractical for pixel-by-pixel analysis to generate parametric images of these parameters. In this study, we investigated several fast parameter estimation methods for the parametric image generation and compared their statistical reliability and computational efficiency. Materials and Methods: These methods included linear least squres (LLS), linear weighted least squares (LWLS), linear generalized least squares (GLS), linear generalized weighted least squares (GWLS), weighted Integration (WI), and model-based clustering method (CAKS). ${H_2}^{15}O$ dynamic brain PET with Poisson noise component was simulated using numerical Zubal brain phantom. Error and bias in the estimation of rCBF and partition coefficient, and computation time in various noise environments was estimated and compared. In audition, parametric images from ${H_2}^{15}O$ dynamic brain PET data peformed on 16 healthy volunteers under various physiological conditions was compared to examine the utility of these methods for real human data. Results: These fast algorithms produced parametric images with similar image qualify and statistical reliability. When CAKS and LLS methods were used combinedly, computation time was significantly reduced and less than 30 seconds for $128{\times}128{\times}46$ images on Pentium III processor. Conclusion: Parametric images of rCBF and partition coefficient with good statistical properties can be generated with short computation time which is acceptable in clinical situation.
Journal of the Korean Institute of Traditional Landscape Architecture
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v.39
no.2
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pp.29-38
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2021
According to the theory of concentration recovery(ART), experiencing landscapes with healing properties can heal human mental fatigue caused by intentional concentration. The ART illustrates four healing qualities of the landscape. ART admits that various landscapes can have healing properties, the four healing properties of the landscape explained that the greater the perceptual strength, the stronger the healing effect. Until now, research on healing landscapes has been mainly done on natural and urban landscapes. The purpose of this study is as follows. First, eIt is intended to evaluate the healing characteristics of the Yangdong village landscape using RCS and investigate the impact of the healing characteristics on the visiting preference of the target landscape. Second, Evaluating the landscape image of Yangdong Village landscape, Investigating the effect of landscape images on the healing properties of landscape. This study was conducted in Yangdong Village, Gyeongju, 127 college students participated in the survey. SD 16 items to analyze landscape images and RCS 22 items from Laumann(2001) to evaluate healing properties were used as measurement tools. The findings are summarized as follows. First, The landscape image of Yangdong Village was analyzed through SD method, the analysis of the factors of Yangdong Village landscape image results in two factors: place and singularity. Second, It demonstrates the reliability and validity of RCS, Three factors were extracted from the factor analysis results. Third, Landscape images have a positive effect on the three healing characteristics of RCS. Fourth, Three healing properties of RCS have been shown to have a positive effect on visiting preferences, The order of influence on the relative visiting preferences was analyzed as attractiveness, fit, sense of escape, and sense of space. The findings suggest that future work requires research to re-validate the reliability of RCS. It is also necessary to analyze landscape images for various landscape types to specifically understand the effects on healing characteristics.
This research is an attempt to establish a basic material in discovering the subjective types of the dental coordinators occupational consciousness, utilizing the Q-Method Theory, which is capable of measuring the subjective nature of human being by scientific and systematic method. The characteristics of each type were analyzed so as to have the dental coordinator to possess the desirable understanding of the occupational view together for them to have self-confidence as a lifetime specialty occupation. Upon completion of the study, it was found that there are three types of subjective views pertaining to the occupational consciousness on the dental coordinator. The result on the analysis of the characteristics is as follows : Type 1 is the Taking Serious View on the Patient Service, which priority is placed on kindness and looking after any difficulties of the patient, namely, it is the type that puts the importance on the high level medical examination and treatment based on good service. Because of the kind service to the patient, those under this category considered their job satisfaction have been improved. It goes without saying that they were developing the services, which satisfy themselves, and it was confirmed that they thought that they should make things smooth for any development of problems that may arise between the patient and the dentist. Type 2 is the Taking Serious View on Career and Organizational Strength. This is a type that aims on the systematic nature of the internal job, namely, organizational strength itself viewed from the stand point thai either self-confident or work merit is proportional to experience. This type is to actively treat the problem and endeavor to solve the issue when dissatisfaction is held by the dental hospital system, which is either followed according to the work responsibility or by an organization having an appropriate system on remuneration, Type 3 is the Placing of Importance on the Overall Circumstances. This is the type that places importance on the overall now of the dental hospital, and it is the type, that most greatly recognizes the importance of the role of the dental coordinator. The dental coordinator should provide the sense of reliability to both the dentist and to the staff of the medical examination and treatment and should be able to adjust smoothly the overall now of the medical treatment. The dental coordinator is expected to be a medical service specialist, who is capable to solve the problems of the staff of the medical treatment intuitively and to adjust the relation between the employees. With the above result, it was found that although there was no mutual exclusiveness between the respective types, there are particular characteristics among each type. Therefore, this research has discovered and analyzed the subjective view types relative to the occupational consciousness of the dental coordinator for the proper understanding on the characteristics of each type to enable the dental sanitary students and the graduates of the Dental Sanitary Department, who are aspiring to become dental coordinator, as the basic guide material to be actively utilized.
The sense of crisis on seriousness of earth environment is gradually getting greater and the importance of environment education followed by this trend is being highlighted. As an environment friendly New Environmental Paradigm opposed to the human Dominant Social Paradigm on the existing environment is on the rise, the environment education considers not only the perceptive field, but the definitive field and behavioral pattern to follow as important values. Accordingly, the basic awareness of students on environment was found out in order to perform a proper environment education and tried to find out the behavior pattern that the students have on environment on this basis. For the research tool of this study, the one that has revised the Revised NEP Scale for elementary school students which Geum, Ji Hun Kim, Jin Mo have validated the feasibility and reliability while the test paper was prepared by dividing into recycling behavior, energy preservation behavior and source of information. The target of this study was 600 students in sixth grade of elementary school residing in Kimhae, Gyeongsangnamdo while the mean, average, standard deviation, independent t-test and correlation analysis were performed using SPSS 15.0 statistics program for a total of 462 copies including 235 copies from male students and 227 copies from female students. The results of this study are as follows. First, everyone had high pro-NEP tendencies on the environmental problem with 4.14. On the other hand, the anti-NEP did not have high awareness standard with 2.98. Second, the awareness level on resource recycling was shown as being quite high with 4.05. Between NEP and resource recycling, a positive correlation of r=.155 was shown so that the awareness level on resource recycling was getting quite high as the awareness on environment problem was getting higher. Third, the awareness level on energy saving activity was shown as being very high with 3.0. Between NEP and resource recycling, a positive correlation of r=.210 so that the awareness level on energy saving was getting quite high as the awareness on environment problem was getting higher. Fourth, for the source of information on environmental problems of region, our country and global village, the television and internet were shown as main sources of information while the ratio of positive answers on teachers and region as sources of information was shown as quite low.
Seo, Kyung-Hwa;Hwang, Jung-Hyun;Lee, Eun-Yong;Lee, Soo-Bum
Culinary science and hospitality research
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v.19
no.1
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pp.12-25
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2013
This study conducted an empirical analysis on the hypothesis of structural relationship that the resources of diversification foodservice corporations develop into resource sharing about creating synergy on the basis of resource based view. Based on the questionnaire answered by 237 foodservice employees over three years, this study examined its validity and reliability by using SPSS 16.0 and AMOS 5.0 for hypothesis. The result of study modelling were GFI=0.910, NFI=0.915, CFI=0.952, RMSEA=0.070 at the level of $x^2$=179.797(df=83, p<0.001). First, intangible resources 0.180(t=2.371, p<0.05), tangible resources 0.127(t=2.028, p<0.05) and human resources 0.263(t=2.542, p<0.05) of diversification foodservice corporations had positive effects on resource sharing. And resource sharing 0.264(t=3.158, p<0.001) had a positive effect on synergy. Also, between resource sharing and synergy identified moderating effects by synergy implementation cost.
Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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v.22
no.4
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pp.1-12
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2008
The aim of this study is to investigate the sensitivity evaluation of human beings in reacting to the correlated color temperature of the optical properties of white LED lighting. For the sake of this study, white light-emitting diode modules have been fabricated their correlated color temperature have been measured, test cabinets for the sensitivity evaluation have been constructed with the white LED modules, and their sensitivity reactions on the test cabinets have been evaluated and analyzed. The sensitivity reaction has been evaluated by the semantic differential method with 15 selected questions, and the reliability and the content validity of their lighting have been analyzed to 3 factors which foe the activity as the first factor, the stability as the second one, the potency as the third one, respectively. For the data analysis on the sensitivity reaction, the dependent variable is the score of the sensitivity evaluation and the independent one is the correlated color temperature of the test module. The results of this study is as follows: In the case of the sensitive evaluation on the activity and the potency in the white LED lighting compared with the fluorescent lamp, the subjects have made higher mark on $MA_3$ with 8,300[K], and in the factor of the stability, they have made higher mark on $MA_1$ with 3,800[K].
This study is conducted to analyse the process and the pattern of motivation for musical expression in clinical music therapy for the adults in the mental health center. The participant were 8 adults purposive sampling who had more than one year music therapy experience in the mental health center and their age ranged from 27 to 53. A major category derived and analysed from the grounded theory method by Strauss and Corbin. The qualitative analysis indicated that motivation for musical expression in music therapy, which was the central phenomenon in this study, was determined by the music therapist and songs used in the sessions. The central phenomenon was caused by the therapist's friendly attitude, high musical capacity, the familarity of the selected songs and the significancy of the lyrics of selected songs. The levels of reliability about the therapist's personality and musical ability as a professional music therapist and the positive arousal of the songs used in sessions affected as the contextual condition. Spontaneous musical expression in music therapy brought the escape from reality, release of stress and sharing by the intervening condition 'empathy' and this resulted in mood regulation, the instillation of hope and group cohesion. It has been found that there were three types of motivation in music therapy: intrinsic motivation, relationship dependent extrinsic motivation and evasive motivation.
In this study, we described a paper-based neuraminidase assay sensor (PNAS) which can be applied to detect the infection by influenza viruses. The PNAS was designed and manufactured to quantitatively identify the levels of neuraminidase in the sample, which is based on colorimetric analysis using the X-Neu5Ac substrate. The limit of detection of the PNAS was determined as 0.004 U/mL of neuraminidase. According to the amount of neuraminidase in human serum, the PNAS could monitor the enzyme activity with a good linearity ($R^2$ > 0.99). In addition, the initial performance of the PNAS has been maintained up to 70 days in the $4^{\circ}C$. Finally, we demonstrated whether the Michaelis-Menten kinetics is applied to the PNAS, which can show the reliability of the enzyme reactions. The kinetic studies indicated that the PNAS provides the good condition for enzyme reactions ($K_m=8.327{\times}10^{-3}M$), but they were performed on paper chip nonetheless. The paper-based neuraminidase assay sensor may be useful in a wide range of rapid and safe detection of influenza virus.
This study investigated the relationship among home care nurses' perception of ethical values and conflicts and job satisfaction. The subjects of the study were 257 home care nurses working at 101 institutions involved in home care practice, the data were collected between December 28, 2004 February 14, 2005. The instruments were perception of ethical values, ethical conflicts, and job satisfaction and it was revised by the author. The reliability of Cronbach's a was .74, .93, .85, respectively. SAS 8.0 program was used to analyze the data, and frequency, percentage, unpaired t-test, ANOVA, $Scheff\`{e}$ test, and Pearson's Correlation Coefficient were calculated for data analysis. Followings are the results of the study: The scores of home care nurses' perception of ethical values were average 3.8points (5points scale). There was no significant difference between the groups according to general characteristics such as age (P=.001), religions (P=.001), ethical standard (P=.018), and current job satisfaction (P=.000). The scores of home care nurses' ethical conflicts were average 2.9points (5points scale). There was significant difference according to pay (P=.008) and employment status (P=.001) of general characteristics; conflicts was showed to go up with higher pay and temporary employment status. The scores of home care nurses' job satisfaction were average 3.3points (5points scale). There was significant difference among the groups according to age (P=.023), pay (P=.001), job career of home care (P=.030), and current job satisfaction (P=.000) of the general characteristics. There was significant positive correlation between subject's perception of ethical values and ethical conflicts (P=.004) and perception of ethical values and job satisfaction (P=.005). However, ethical conflicts and job satisfaction (P=.772) showed negative correlation, but it was not significant. With the results, home care nurses showed firm perception of ethical values and relatively higher job satisfaction. However, they showed ethical conflicts regarding the lack of administrative support and dignity of human life. In conclusion, It requires some alternative measures to solve the ethical conflicts and to enhance job satisfaction of home care nurses through the support in policy, continuous ethics education, rewarding system, and introducing laws to protect individual home care nurses.
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