• Title/Summary/Keyword: health technology assessment

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The Change of the Fracture Risk by a Fracture Risk Factor in the FRAX Tool (FRAX Tool에서 골절위험인자에 따른 골절위험도의 변화)

  • Song, Hyeon-Seok;Lee, Hyo-Yeong;Yun, Jong-Jun;Lee, Hwa-Jin;Lee, Moo-Seok;Park, Sae-Yoon;Jeong, Ji-Wook
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.3
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    • pp.132-136
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    • 2009
  • Purpose: WHO(world health organization) announced the FRAX Tool(fracture risk assessment) of new software in the beginning of 2008. FRAX Tool was considered various risk factor, being different from existing fracture risk. In this study, we wanted to know the fracture risk of following the changing of the risk factor of fracture. Materials and Methods: A total of 50 women aged 50~60 were studied. We measured BMD at the part of femur neck which was based on the age, weight, height of individual with GE, Lunar-prodigy. The control group is fracture risk without considering fracture risk factor. The experimental group is previous fracture, parent fracture, current smoking, glucocorticoid, rheumatoid arthritis, secondary osteoporosis, alcohol. if each items makes one 'existence', others are all 'nothing'. and the results produced major osteoporotic region and hip fracture risk in 10-years. Statistics used t-test of SPSS 12.0. Results: The average rate of increment of major osteoporotic region between control group and experimental group, previous fracture-74% increase, parent fracture-96% increase, current smoking-2% increase, glucocorticoid-61% increase, rheumatoid arthritis-29% increase, alcohol-20% increase, secondary osteoporosis-0.18% decrease. The average rate of increment of hip region between control group and experimental group, previous fracture-84% increase, parent fracture-5% increase, current smoking-72% increase, glucocorticoid-84% increase, rheumatoid arthritis-40% increase, alcohol-52% increase, secondary osteoporosis-1.69% decrease. Conclusions: Each fracture risk factor has different rate of increment between major osteoporotic and hip region while in occasion of the second osteoporosis it has little relation because of low P-value. We could know that a contribution of the risk factor is different between major osteoporotic and hip region.

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Changes of Radiation Dose and Image Quality Due to Additional Filtration Material in Computed Radiography (Computed Radiography에서 Additional Filtration Material에 따른 Radiation Dose와 Image Quality의 변화)

  • Kwon, Soon-Mu;Cho, Hyung-Wook;Kang, Yeong-Han;Kim, Boo-Soon;Kim, Jung-Su
    • Journal of radiological science and technology
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    • v.37 no.4
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    • pp.239-246
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    • 2014
  • Filter absorbs low-energy X-ray to increase the average energy and reduces patient exposure dose. This study investigates if the materials of Mo and W could be used for the digital imaging device CR by conducting image assessment and dose measurement of SNR, FOM and histogram. In addition, measurement of beam quality was conducted depending on the material of the filter, and at the same time, a proper combination of filters was examined depending on the change in tube voltage (kVp). In regard to entrance skin dose, Mo filter showed the dose reduction by 42~56%, compared to Cu filter. Moreover, Mo filter showed higher transmission dose by around 1.5 times than that of Cu filter. In image assessment, it was found that W was unsuitable to be used as a filter, whereas Mo could be used as a filter to reduce dose without decline in image quality at the tube voltage of 80 kVp or higher. As tube voltage increased, 2.0 mm Al+0.1 mm Mo almost had a similar histogram width to that of 2.0 mm Al+0.2 mm Cu. Therefore, Mo filter can be used at relatively high tube voltage of 80 kVp, 100 kVp and 120 kVp. The SNR of 2.0 mm Al+0.1 mm Mo did not show any significant difference from those of 2.0 mm Al+0.2 mm Cu and 2.0 mm Al+0.1 mm Cu. As a result, if Mo filter is used to replace Cu filter in general radiography, where 80 kVp or higher is used for digital radiation image, patient exposure dose can be reduced significantly without decline in image quality, compared to Cu filter. Therefore, it is believed that Mo filter can be applied to chest X-ray and high tube voltage X-ray in actual clinical practice.

Assessment of dust exposure and personal protective equipment among dental technicians (치과기공사의 분진노출 수준 및 개인보호구 착용 실태 - 대구지역을 중심으로 -)

  • Park, Soo-Chul;Jeon, Man-Joong;SaKong, Joon
    • Journal of Technologic Dentistry
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    • v.33 no.1
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    • pp.93-102
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    • 2011
  • Purpose: The study aimed to evaluate working environment for dental technician by measuring dust level, ventilation conditions and the use of personal protective equipment and to provide basic information required to improve working environment and develop health education programs for dental technician. Methods: A total of 240 dental technician who are registered with the Daegu Association of Dental technician and working at 34 dental laboratories participated in the study. And the dust level was measured at 21 different spots in 16 dental laboratories out of 34. Results: Of 34 dental laboratories, 31 (91.2%) were equipped with a ventilator, but the remaining 3 (8.8%) did not have a ventilator. By the number of ventilator, 1 to 3 ventilators were found in 22 dental laboratories (71.0%), 4 to 6 ventilators were in 7 laboratories (22.5%) and more than 7 ventilators in 2 laboratories(6.5%). According to the frequence of changing filters in dust collector, 20 dental laboratories (58.9%) changed filters every four weeks, 10 laboratories (29.4%) changed them every six weeks and 4 laboratories (11.7%) changed them every eight weeks. Of total respondents, 114 (61.3%) said they wore a mask all the time while working, 56 (29.6%) said they frequently wore a mask, 19 (10.1%) said they did not wear a mask. As for the type of masks, 159 (84.1%) used a disposable mask, 25 (13.2%) used a cotton mask and 5 (2.7%) used an anti-dust mask. For dust sat on their outfits while working, 102 (54.0%) shook their uniforms inside workplace to keep dust off the uniforms, 64 (33.9%) did not anything until they wash their uniforms and 23 (12.1%) shook their uniforms outside workplace to keep dust off the uniforms. Of total respondents, 182 (96.3%) had a particle in their eyes while carrying out grinding work. Based on the measurement of floating dust at workplace, 3 dental laboratories showed dust concentration exceeding the minimum level of 10 mg/$m^3$ allowed under the permit for environment. Of those, 1 laboratory had the dust concentration that was more than 1.5 times higher than the minimum level. Dust concentration was higher in laboratories that used a dust collector with 0.5 horse power and changed filters more than 3 weeks ago. Dust comprised of nickel (more than 70%), chrome (9%) and others. The mean chrome concentration was more than twice higher than the minimum permissible level of 0.5 mg/$m^3$. There were two laboratories that showed chrome concentration exceeding the level of 0.4 mg/$m^3$. Like dust concentration, chrome level was higher in laboratories that used a dust collector with 0.5 horse power and changed filters more than 3 weeks ago. There were six laboratories that had nickel concentration exceeding the minimum permissible level of 1 mg/$m^3$. Of those, one laboratory had nickel concentration that was more than three times higher than the minimum permissible level. Nickel concentration was also higher in laboratories that used a dust collector with 0.5 horse power and changed filters more than 3 weeks ago. Conclusion: It is not likely that heavy metal concentrations found in the study constitute respiratory dust. It is however necessary for health of dental technician to apply the Industrial Safety and Healthy Law to dental laboratories and make recommendations for the use of personal protective equipment, installation of a proper number of ventilators, more frequent change of filters in dust collector and improved ventilation for polishing work. At the same time, dental technician need education on how to use personal protective equipment and how to efficiently remove dust from their uniforms.

The Study of distribution relationship of dioxin isomers in some environmental matrix (몇 가지 환경 시료 중에 함유된 다이옥신류 이성질체들의 분포에 대한 상관성 연구)

  • Kim, Yunje;Jun, Myung Yoon
    • Analytical Science and Technology
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    • v.18 no.5
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    • pp.419-424
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    • 2005
  • In recent years, dioxins which were designated as persistent organic pollutants and endocrine disrupters are treated as substance of environmental pollution and studied about human health risk assessment, emission pollutants estimation, analytical methods and so on. It is easy that dioxins are accumulated to soil because of the atmosphere circulation of burning up the waste. This is the comparative studies on the distribution relationship of dioxin isomers in exhausted gas of industrial waste and urban waste incinerators, ambient air and soil. A basis of PCDDs and PCDFs based on OCDD was drawn up to the curve and they correspond to dioxin isomers in exhausted gas of industrial waste and urban waste incinerators and ambient air. On comparing these results, It was found that the ambient air and exhausted gas of industrial waste incinerators were very similar in curve and ratio. Consequently, environmental by exposed dioxin depends on the exhausted gas of industrial waste incinerators than urban waste incinerators. In case of soil, even though we can not completely rule out the possibility of pollution source bring on pesticide and other factors, and naturally biological dissociations, the curve shape is very similar to exhausted gas of industrial waste incinerators and ambient air. So, we inform here that it was mainly caused by these environmental factors.

Usefulness Assessment of Automatic Analysis Program for Flangeless Esser PET Phantom Images (Flangeless Esser PET Phantom 영상 자동 분석 프로그램의 유용성 평가)

  • NamGung, Chang-Kyeong;Nam, Ki-Pyo;Kim, Kyeong-Sik;Kim, Jeong-Seon;Lim, Ki-Cheon;Shin, Sang-Ki;Cho, Shee-Man;Dong, Kyung-Rae
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.1
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    • pp.63-66
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    • 2009
  • Purpose: ACR (American College of Radiology) offers variable parameters to PET/CT quality control by using ACR Phantom. ACR Phantom was made to evaluate parameters which are uniformity, attenuation, scatter, contrast and resolution. Manual analysis method wasn't good for the use of QC because values of parameter were changed as it may user and it takes long time to analysis. Ki-Chun Lim, a nuclear scientist in AMC, developed program that automatically analysis values of parameter by using ACR Phantom to overcome above problems. In this study, we evaluated automatic analysis program's usability, through the comparing SUV of each method, reproducibility of SUV when repeated analysis and the time required. Materials and Methods: Using Flangeless Esser PET Phantom, the ideal ratio of 4 : 1 hot cylinder and BKG but it actually showed a ratio of 3.89 to 1 hot cylinder and BKG. SIEMENS Biograph True Point 40 was used in this study. We obtained images using ACR phantom at Fusion WB PET Scan condition (2 min/bed) and 120 kV, 100 mAs CT condition. Using True X method, 3 iterations, 14 subsets, Gaussian filter, FWHM 4 mm and Zoom Factor 1.0, $168{\times}168$ image size. We obtained Max. & Min. SUV and SUV Mean values at Cylinder (8, 12, 16, 25 mm, Air, Bone, Water, BKG) by automatic program and obtained SUV by manual method. After that, we compared manual and automatic method. we estimate the time required from opened the image data to final work sheet was completed. Results: Automatic program always showed same result and same the time required. At 8, 12, 16 and 25 m cylinder, manual method showed 6.69, 3.46, 2.59, 1.24 CV values. The larger cylinder size became, the smaller CV became. In manual method, bone, air, water's CV were over 9.9 except BKG (2.32). Obtained CV of Mean SUV showed BKG was low (0.85) and bone was high (7.52). The time required was 45 second, 882 second respectably. Conclusions: As a result of difference automatic method and manual method, automatic method showed always same result, manual method showed that the smaller hot cylinders became, the lager CV became. Hot cylinders mean region size, the smaller hot cylinder size becomes we had some trouble in doing ROI poison setting. And it means increase in variation of SUV. The Study showed the time required of automatic method was shorten then manual method.

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Performance Evaluation of Domestic Prototype Dose Area Product Meter SFT-1 (국산 프로토타입 면적선량계 SFT-1의 성능평가)

  • Lee, Ho-Sun;Han, Seong-Gyu;Roh, Young-Hoon;Lim, Hyun-Jong;Kim, Jung-Min;Kim, Jong-Uk;Chae, Hyun-Sik;Yoon, Yong-Su
    • Journal of radiological science and technology
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    • v.39 no.3
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    • pp.435-441
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    • 2016
  • The importance of radiation dose display of medical X-ray equipment was emphasized, while third edition of IEC(International Electrotechnical Commission) 60601 started to apply. The existing medical X-ray equipment selected a method for attaching the DAP(Dose Area Product) meter when the dose display. However, because the DAP meter was dependent on all of the income, And it did not yet produced in Korea. So, we received the support of Seoul R&BD Program(Grants No. C1152055) to produce DAP meter prototype of the Domestically technology. In this study, the performance of this prototype was evaluated by comparing the German company's product Evaluation item was an electronic capture performance, radiation dose dependence, radiation quality dependence, energy transmittance, repeatability, light transmittance of 6 entries. And IEC 60580 was based on this evaluation. Evaluation results were electronic capture performance intrinsic error 9.5%, radiation dose dependence limits of variation 1%, repeatability coefficient of variation 2%, energy transmittance 91% each assessment was passed. However radiation quality dependence limits of variation 29%, light transmittance 55% was less than acceptance criteria.

Method Validation for Monitoring of Agricultural Worker Exposure to Insecticide Fenthion (살충제 Fenthion에 대한 농작업자 노출 측정을 위한 분석/시험방법 검증)

  • Kim, Eun-Hye;Lee, Hye-Ri;Choi, Hoon;Moon, Joon-Kwan;Hong, Soon-Sung;Jeong, Mi-Hye;Park, Kyung-Hun;Lee, Hyo-Min;An, Xue Hua;Kim, Jeong-Han
    • The Korean Journal of Pesticide Science
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    • v.15 no.4
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    • pp.357-365
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    • 2011
  • Exposure measurement of agricultural worker to pesticide is one of important part of health risk assessment of pesticide. Therefore exposure matrices, apparatus, instruments and methods must be validated in advance to field experiment. In this study, method validation with an organophosphorus insecticide fenthion was carried out for exposure monitoring of agricultural worker. LOD and LOQ were 0.01 and 0.05 ng, respectively. Calibration curve linearity ($R^2$ > 0.999) and reproducibility (C.V. < 3%) were also excellent. Recovery at LOQ, 10LOQ and 100LOQ levels from gloves, socks, mask, patch, solid sorbent, glass fiber filter was 76~113% (C.V. < 3%). Trapping efficiency was 95~105% while no breakthrough was observed. Method validation for the exposure monitoring was established successfully through several experiments. Such method validation can be usually performed in laboratory and not much different for each pesticide so that, this techniques will be applied widely in research for pesticide exposure monitoring by combination with body surface area and respiration rates.

Effects of dietary humic acid and enzymes on meat quality and fatty acid profiles of broiler chickens fed canola-based diets

  • Disetlhe, Amogelang R.P.;Marume, Upenyu;Mlambo, Victor;Hugo, Arno
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.5
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    • pp.711-720
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    • 2019
  • Objective: This study was conducted to assess the effect of potassium humate and enzymes (Xylanase+Amylase+Protease) inclusion in diets on carcass characteristics, meat quality and fatty acid profiles of broilers fed canola-based diets. Methods: Two hundred and twenty broilers randomly allotted to 5 dietary treatments: the control (commercial broiler diet); CM (17.5% canola meal inclusion); CMEnz (17.5% CM inclusion+0.3 g/kg Axtra XAP); CMPh (17.5% CM inclusion+1.5% Potassium Humate, PH); and CMEnzPh (17.5% CM inclusion+1.5% PH+0.3 g/kg Axtra XAP) were slaughtered at day 42 for assessment of carcass and meat quality parameters. Results: Diet had no effect on carcass traits apart from breast muscle weight and breast muscle index. The highest breast muscle weight was observed in broilers fed CMEnz ($487.6{\pm}17.5g$) followed by those fed the control diet ($474.37{\pm}17.5g$). Diet also had no significant dietary effect on pH, temperature, drip loss and shear force values of the breast muscle. However, diet significantly affected meat colour and water-holding capacity. Broilers in the control and CMPh groups ($52.94{\pm}0.67$ and $52.91{\pm}0.67$) had the highest (p<0.05) values for lightness ($L^*$), whilst those fed CMEnzPh had the lowest value ($47.94{\pm}0.67$). In contrast, CM group had the lowest (p<0.05) value for redness ($a^*$) with CMEnzPh group having the highest values. The proportion of polyunsaturated fatty acids (PUFAs), n-6 and n-3 fatty acids and the PUFA/saturated fatty acid ratio were increased in CM-based diets containing enzymes and humic acid. Conclusion: It can, therefore, be concluded that CM can be included in broiler diets in the presence of enzymes and humic acid with positive effects on meat quality and important fatty acids that are beneficial to the health of consumers.

A Study on the Prediction of Mortality Rate after Lung Cancer Diagnosis for Men and Women in 80s, 90s, and 100s Based on Deep Learning (딥러닝 기반 80대·90대·100대 남녀 대상 폐암 진단 후 사망률 예측에 관한 연구)

  • Kyung-Keun Byun;Doeg-Gyu Lee;Se-Young Lee
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.16 no.2
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    • pp.87-96
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    • 2023
  • Recently, research on predicting the treatment results of diseases using deep learning technology is also active in the medical community. However, small patient data and specific deep learning algorithms were selected and utilized, and research was conducted to show meaningful results under specific conditions. In this study, in order to generalize the research results, patients were further expanded and subdivided to derive the results of a study predicting mortality after lung cancer diagnosis for men and women in their 80s, 90s, and 100s. Using AutoML, which provides large-scale medical information and various deep learning algorithms from the Health Insurance Review and Assessment Service, five algorithms such as Decision Tree, Random Forest, Gradient Boosting, XGBoost, and Logistic Registration were created to predict mortality rates for 84 months after lung cancer diagnosis. As a result of the study, men in their 80s and 90s had a higher mortality prediction rate than women, and women in their 100s had a higher mortality prediction rate than men. And the factor that has the greatest influence on the mortality rate was analyzed as the treatment period.

Development and Assessment of an ICT-Based Non-Face-to-Face Lifestyle Program to Improve the Mental Health of Older Adults: A Pilot Study (고령자의 정신건강을 위한 ICT 기반 비대면 라이프스타일 프로그램: 파일럿 연구)

  • Lee, Hey Sig;Park, Hae Yean;Jung, Min-Ye;Park, Ji-Hyuk;Hong, Ickpyo;Kim, Jung-Ran
    • Therapeutic Science for Rehabilitation
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    • v.13 no.1
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    • pp.99-114
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    • 2024
  • Objective : This study aimed to develop an information and communication technology (ICT)-based, non-face-to-face lifestyle program for older adults and assess its applicability. Methods : The program was developed on the basis of the ADDIE model which comprises 5 stages: analysis, design, development, implementation, and evaluation. In this study, a step-by-step identification was performed in 8 stages. Results : The results of the program analysis showed a significant decrease in depressive symptoms and loneliness scores, and an increased quality of life scores. Conclusion : The findings suggest that the ICT-based non-face-to-face lifestyle program developed in this study can motivate older adults to better understand their lifestyles for successful aging, while helping senior citizen centers resume stagnant projects.