• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3887-3891
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• 2015

Aloe-emodin (1, 8-dihydroxy-3-hydroxyl-methylanthraquinone; AE) and emodin (1,3,8-trihydroxy-6-methylanthraquinone; EM) are anthraquinone derivatives that have been detected in some medical plants and share similar anthraquinone structures. AE and EM have been shown to exhibit anticancer activities in various cancer cell lines; however, the inhibitory effects of these derivatives on the growth of cancer cells were previously reported to be different. Gastric cancer is the second most common cause of cancer cell death worldwide. In the present study, we examined the inhibitory effects of 0.05 mM AE and 0.05 mM EM on the proliferation of the MKN45 human gastric cancer cell line. The proliferation of MKN45 cells was significantly inhibited in AE- and EM-treated groups 24 h and 48 h after treatment. Furthermore, the inhibitory effects of EM were stronger than those of AE. The cell cycle of MKN45 cells were arrested in G0/G1 phase or G0/G1 and G2/M phases by AE and EM, respectively. However, an analysis of intracellular polyamine levels and DNA fragmentation revealed that the mechanisms underlying cell death following cell arrest induced by AE and EM differed.

• 대한간호학회지
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• 제46권1호
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• pp.140-148
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• 2016

Purpose: This study was performed to determine the physical and psychological effects of an urban forest-walking program for office workers. For many workers, sedentary lifestyles can lead to low levels of physical activity causing various health problems despite an increased interest in health promotion. Methods: Fifty four office workers participated in this study. They were assigned to two groups (experimental group and control group) in random order and the experimental group performed 5 weeks of walking exercise based on Information-Motivation-Behavioral skills Model. The data were collected from October to November 2014. SPSS 21.0 was used for the statistical analysis. Results: The results showed that the urban forest walking program had positive effects on the physical activity level (U=65.00, p <.001), health promotion behavior (t= - 2.20, p =.033), and quality of life (t= - 2.42, p =.020). However, there were no statistical differences in depression, waist size, body mass index, blood pressure, or bone density between the groups. Conclusion: The current findings of the study suggest the forest-walking program may have positive effects on improving physical activity, health promotion behavior, and quality of life. The program can be used as an effective and efficient strategy for physical and psychological health promotion for office workers.

• 한국학교ㆍ지역보건교육학회지
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• 제16권1호
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• pp.83-92
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• 2015

Objectives: This thesis intends to find out the extent of drinking problem which is caused by students' psychosocial stress, expected alcohol effects and problem drinker drinking as well as the influence of each factor. Methods: This study was conducted from September 1, 2014 to October 31, 2014 with the target of 466 students (66.6%), who are currently drinking, out of 700 students over the age of 16 and enrolled in 36 universities located in the whole country. This data were analyzed using the program SPSS21. Results: Age, gender, and the school district that showed significant differences in drinking problem compared to other general characteristics played the role of control variables. It was found that psychosocial stress does not affect the drinking problem. The self-reward and human-relation factors included in the expected drinking effect were revealed to influence significantly on the problem and the life and health related factors included in the reason of drinking refrain were also turned out to have significant effect on that problem. The degree of F is 15.665 and the degree of explanatory is 23.6%. Conclusions: Problem drinker in college and enhance the culture and health education policy is necessary to reduce college student drinking effects expected.

• Journal of Preventive Medicine and Public Health
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• 제36권3호
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• pp.298-301
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• 2003

Objectives : There is an increasing concern for the social, economic, environmental and health effects of the Asian dust (Hwang-sa in Korean language) in Korea. In this study, we intended to indirectly determine ordinary people's perception about the Asian dust by analyzing the contents of newspaper articles dealing with it. Methods: By using article searching services in the internet websites of three newspaper companies, we collected newspaper articles dealing with the Asian dust during the period from January $1^{st}$ of 1998 to December $31^{st}$ of 2002. We classified the articles into four categories: those forecasting the occurrence of the Asian dust, those about measures to cope with it, those about its occurrence in the neighboring foreign countries, and those about its effects. In particular, we analyzed articles about the health effects of the Asian dust more distinctly. Results : A total of 1,225 articles dealing with the Asian dust were found during the 5 year period. The number of articles increased from 102 in 1998 to 518 in 2002, approximately a five-fold increase, The numbers of articles about health effects, environmental effects and economical effects were 191 (44%), 171 (41%) and 147 (34%), respectively. It was reported that various diseases such as respiratory diseases (87%), eye problems (69%), and skin diseases (12%) were associated with the Asian dust. Conclusion : The increasing concern for the negative effects of the Asian dust necessitates more studios about this field. As the effects of the Asian dust are various, the information on the major concern of ordinary people could help establish the research agendas and measures for the Asian dust.

• 한국환경보건학회지
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• 제44권5호
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• pp.409-420
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• 2018

Objectives: An outbreak of humidifier disinfectant-related respiratory disease has not only been a massive disaster for end users, but it is also a concern for the workers of the manufacturers. This study presents the results of a questionnaire survey on the health effects among workers involved in the manufacture of humidifier disinfectants. Methods: Seven sites where humidifier disinfectants were manufactured were identified. A questionnaire survey was conducted to assess the physical symptoms experienced by workers related to humidifier disinfectants. Among a total of 177 workers, 42 subjects were available for the survey. Results: Twenty-one of the 42 respondents reported that they experienced respiratory or skin and mucosal irritation symptoms during work. Of the respondents who experienced symptoms, 14 believed that their symptoms were related to the work process and reported that the symptoms were experienced while working. However, no respondents reported ongoing symptoms or sequelae during the investigation period, and this result could not minimize selection bias due to low response rates. We then compared the characteristics of the group who experienced suspicious symptoms with those of the group without any symptoms. There was no statistically significant difference between two groups. Conclusions: We could not find significant health effects related to the humidifier disinfectant manufacturing process, although 21 respondents experienced stimulant symptoms and 14 respondents believed that the symptoms were related to the work process. Due to the long period of time after occupational exposure and the lack of data, there were many limitations to this study. However, this is one of the few follow-up investigations of workers related to this large-scale disaster in South Korea and the limitations of this study highlight the need to follow up with a nationwide database rather than an occasional survey.

• 한국환경보건학회지
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• 제33권5호
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• pp.345-352
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• 2007

As mercury absorbed into body can cross the blood-brain barrier and react with DNA and RNA. Central nervous system has been known to be affected especially in children. But it was very difficult to know the influences of chronic low-does Hg exposure on the health. Although many studies investigated the affect, most of results were still disparate. In order to investigate the health effects of mercury exposure, several test were conducted for some Korean school children. The general health effects were investigated using blood test, Posturography and computer-based neurobehavioral test was done to examine the affect of Hg into neural responses. About 400 children were chosen for blood test whose blood Hg level were upper and lower 10% of population participated in the nationwide Hg exposure survey. The concentration of calcium and creatine, the number of white and red blood cell showed statistical significance with Hg exposure in blood test. Another 36 children were selected from the same participants for the posturography and neurobehavioral test. The intensity and center frequency of hand tremor which were related to unconsciousness also showed distinct significances. Any general relations with Hg exposure were not found in all test including computer-based neurobehavioral test.

• 한국학교ㆍ지역보건교육학회지
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• 제1권2호
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• pp.73-85
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• 2000

This research has attempted to provide the basic data of health education in middle school students whose positions are very important in health promotion of the whole people. Especially, we are focused on the relationship between their individual family environment and health promotion behaviour. We have surveyed and collected all the information of the effects which has come from the family environment, and given the period from 22nd of May to 27Th with 375 boys and girl students who live in the cities and suburbs of Chung Cheong Buk-D, and used SPSS program in the analyse of the information. The conclusions were as follows; 1. Gender, the residential area, the living pattern with parents, and religion have showed very close effects in the promotion health behavior of the middle school students. 2. Statistically, explained health promotion behavior has got 59% and hygiene and daily life habit in inferior group has 48% with these rates, there should be a special management on those factors. 3. The responsibility according to the value direction factors of home has showed relationship as follows; $\circ$ hygiene and daily life habit(p<.001) $\circ$ communicable disease control(p<.01) $\circ$ mental health(p<.05) $\circ$ health promotion behavior(p<.001) The above results showed that the middle school students health promotion behavior were affected by the responsibility according to the value direction factors of family, the responsibility according to the group characteristics factors of family and psychological process factors of family. With this result, family environment is essential factor for students abilities of building up his/hers health promotion behavior.

• 부모자녀건강학회지
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• 제16권1호
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• pp.11-16
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• 2013

Purpose: Ethiopia is one of the sub-Saharan countries most affected by high maternal and infant mortality. The government has trained health extension workers (HEWs), the community health workers, to deliver preventive and basic curative health services to community residents in Ethiopia. Very few studies have investigated on-the-job educational effects for HEWs on improvement of their knowledge and performance confidence in maternal and child health care (MCH). This study aimed at identifying the educational effects for HEWs in one health center in Tigray, Ethiopia on improvement of their knowledge in MCH. Methods: Twelve HEWs from 6 health posts participated in this study. A health center officer provided a total of 5 educational sessions on antenatal and postnatal care, family planning, and newborn care from August, 2012 to April, 2013. Ten to 12 items regarding the topics were tested before and after each education. Wilcoxon signed rank test was used to analyze the data. Results: All the HEWs were female with average 4-year working experience. Their knowledge significantly increased after education, except the first session. Their satisfaction on education was greater than 45 points out of 50. Conclusion: This study suggests a focused education for HEWs should continue to improve their capacity on MCH.

• 한국치위생학회지
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• 제21권2호
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• pp.151-158
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• 2021

Objectives: The purpose of this study was to identify the effects of general and oral health status on dementia. Methods: Questionnaires were used for the KDSQ-C (Korean Dementia Screening Questionnaires-Cognition) and to investigate the oral health status of the participants. An independent t-test was conducted to analyze the differences between general health and oral health status depending on the normal and suspected dementia groups. Logistic regression analysis was performed to assess the effects of general and oral health status on dementia. Results: Regarding the health status of the subjects assessed by the KDSQ-C, the higher the current health status and the higher the exercise status, the lower was the dementia level (p<0.05). During the assessment of oral health conditions in KDSQ-C subjects, dementia was more suspected in subjects with dental decay and periodontal disease than in those without dental decay (p<0.05). Conclusions: Dementia has been confirmed to be closely related to general and oral health conditions. Therefore, oral health-related programs are essential for dementia prevention programs. Since dental hygienists are best suited for providing oral care to older adults with dementia, it is considered essential to reflect their occupation in future national policies.

• Safety and Health at Work
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• 제13권2호
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• pp.207-212
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• 2022

Background: The public now imposes higher demands on the government than in the past, which has created the role overload faced by low-ranking government employees in China. This research investigates the relationship between role overload and health among low-ranking government employees and explores the mediating effects of burnout. Methods: It draws on a survey of 2064 low-ranking government employees by probability proportionate to size sampling in China's Shandong Province. Structural equation modeling (SEM) methods are used to analyze the data. Results: Both role overload and burnout were found to have negative effects on low-ranking government employees' health; however, the associations varied among the three age groups (less than 36, between 36 and 45, and over 45). Those over 45 reported the highest level of both physical and psychological health, while the youngest age group (less than 36) reported the lowest level of health. Role overload has a direct influence on health among government employees over 45 but not among those below 45. Burnout's mediating effects between role overload and health are significant among all age groups, but most significant among the youngest civil servants below 36. Conclusions: The findings evidenced that both role overload and burnout affect low-ranking government employees' self-reported physical and psychological health. In addition, the effect of age differences in coping with role stressors and burnout should be considered.