References
- Badria FA, Ibrahim AS (2013). Evaluation of natural anthracenederived compounds as antimitotic agents. Drug Discov Ther, 7, 84-9.
- Brenner B, Hoshen MB, Purim O, et al (2011). MicroRNAs as a potential prognostic in gastric cancer. World J Gastroenterol, 17, 3976-85. https://doi.org/10.3748/wjg.v17.i35.3976
- Chan FK-M, Moriwaki K, De Rosa MJ (2013). Detection of necrosis by release of lactate dehydrogenase (LDH) activity. Methods Mol Biol, 979, 65-70. https://doi.org/10.1007/978-1-62703-290-2_7
- Chen R, Zhang J, Hu Y, et al (2014). Potential antineoplastic effects of aloe-emodin: A comprehensive review. Am J Chin Med, 42, 275-88. https://doi.org/10.1142/S0192415X14500189
- Chen S-H, Lin K-Y, Chang C-C, Fang C-L, Lin C-P (2007). Aloe-emodin-induced apoptosis in human gastric carcinoma cells. Food Chem Toxicol, 45, 2296-303. https://doi.org/10.1016/j.fct.2007.06.005
- Chen Y-Y, Chiang S-Y, Lin J-G, et al (2010). Emodin, aloeemodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells. Anticancer Res, 30, 945-52.
- Chun-Guang W, Jun-Qing Y, Bei-Zhong L, et al (2010). Antitumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo. Eur J Pharmacol, 627, 33-41. https://doi.org/10.1016/j.ejphar.2009.10.035
- Evan GI, Vousden KH (2001). Proliferation, cell cycle and apoptosis in cancer. Nature, 411, 342-48. https://doi.org/10.1038/35077213
- Harlev E, Nevo E, Lansky EP, Ofir R, Bishayee A (2012). Anticancer potential of aloes: antioxidant, antiproliferative, and immunostimulatory attributes. Planta Med, 78, 843-52. https://doi.org/10.1055/s-0031-1298453
- Hsiao R-C, Chou Y-E, Tan P, et al (2014). Pterostilbene simultaneously induced G0/G1-phase arrest and MAPKmediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell lines. PLoS One, 9, e105342. https://doi.org/10.1371/journal.pone.0105342
- Hsu C-M, Hsu Y-A, Tsai Y, et al (2010). Emodin inhibits the growth of hepatoma cells: finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells. Biochem Biophys Res Commun, 392, 473-8. https://doi.org/10.1016/j.bbrc.2009.10.153
-
Huang P-H, Huang C-Y, Chen M-C, et al (2013). Emodin and aloe-emodin suppress breast cancer cell proliferation through ER
${\alpha}$ inhibition. Evid Based Complement Alternat Med, 2013, 376123. - Lai J-M, Chang J-T, Wen C-L, Hsu S-L (2009). Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells. Eur J Pharmacol, 623, 1-9. https://doi.org/10.1016/j.ejphar.2009.08.031
- Lam SK, Ng TB (2010). First report of a haemagglutinin-induced apoptotic pathway in breast cancer cells. Biosci Rep, 30, 307-17. https://doi.org/10.1042/BSR20090059
-
Nemoto T, Kamei S, Seyama Y, Kubota S (2001). p53 independent G1 arrest induced by DL-
${\alpha}$ -difluoromethylornithine. Biochem Biophys Res Commun, 280, 848-54. https://doi.org/10.1006/bbrc.2000.4227 -
Ray RM, Zimmerman BJ, McCormack SA, Patel TB, Johnson LR (1999). Polyamine depletion arrests cell cycle and induces inhibitors
$p21^{Waf1/Cip1}$ ,$p27^{Kip1}$ , and p53 in IEC-6 cells. Am J Physiol, 276, c684-91. -
Seidenfeld J, Gray JW, Marton LJ (1981). Depletion of 9L rat brain tumor cell polyamine content by treatment with D, L-
${\alpha}$ -difluoromethylornithine inhibits proliferation and the G1 to S transition. Exp Cell Res, 131, 209-16. https://doi.org/10.1016/0014-4827(81)90420-1 - Shiozaki A, Ichikawa D, Takemoto K, et al (2014). Efficacy of a hypotonic treatment for peritoneal dissemination from gastric cancer cells: An in vivo evaluation. Biomed Res Int, 2014, 707089.
- Suboj P, Babykutty S, Srinivas P, Gopala S (2012a). Aloe emodin induces G2/M cell cycle arrest and apoptosis via activation of caspase-6 in human colon cancer cells. Pharmacology, 89, 91-8. https://doi.org/10.1159/000335659
-
Suboj P, Babykutty S, Valiyaparambil Gopi , et al (2012b). Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-
${\kappa}B$ . Eur J Pharm Sci, 45, 581-91. https://doi.org/10.1016/j.ejps.2011.12.012 - Takahashi A, Kimura F, Yamanaka A, et al (2014). Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis. Cancer Cell Int, 14, 53. https://doi.org/10.1186/1475-2867-14-53
- Thomas T, Thomas TJ (2001). Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci, 58, 244-58. https://doi.org/10.1007/PL00000852
- Verkoelen CF, Romijn JC, Schroeder FH, van Schalkwijk WP, Splinter TAW (1988). Quantitation of polyamines in cultured cells and tissue homogenates by reversed-phase high-performance liquid chromatography of their benzoyl derivatives. J Chromatogr, 426, 41-54. https://doi.org/10.1016/S0378-4347(00)81925-8
- Wang W, Sun Y-P, Huang X-Z, et al (2010). Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathione depletion and MRP1 downregulation. Biochem Pharmacol, 79, 1134-40. https://doi.org/10.1016/j.bcp.2009.12.006
- Xu L, Chan C-O, Lau C-C, et al (2012). Simultaneous determination of eight anthraquinones in Semen Cassiae by HPLV-DAD. Phytochem Anal, 23, 110-6. https://doi.org/10.1002/pca.1331
- Yanagihara M, Katano M, Takahashi-Sasaki N, et al (2005). Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs. Cancer Sci, 96, 620-26. https://doi.org/10.1111/j.1349-7006.2005.00088.x
- Yasui W, Sentani K, Sakamoto N, et al (2011). Molecular pathology of gastric cancer: research and practice. Pathol Res Pract, 207, 608-12. https://doi.org/10.1016/j.prp.2011.09.006
Cited by
- L. extract on oral cancer cells vol.32, pp.10, 2017, https://doi.org/10.1002/tox.22444
- Aloe-Emodin Enhances Tamoxifen Cytotoxicity by Suppressing Ras/ERK and PI3K/mTOR in Breast Cancer Cells vol.45, pp.02, 2017, https://doi.org/10.1142/S0192415X17500215
- Aloe Genus Plants: From Farm to Food Applications and Phytopharmacotherapy vol.19, pp.9, 2018, https://doi.org/10.3390/ijms19092843