• 제목/요약/키워드: group response

검색결과 4,510건 처리시간 0.032초

유색미 겨 아라비녹실레인과 지구성 운동트레이닝이 LPS 처치된 흰쥐의 TLR4 Signaling 단백질 발현에 미치는 영향 (Arabinoxylan Rice Bran and Endurance Exercise Training on the TLR4 Signaling-mediated Protein Expression in LPS-treated Rats)

  • 손희정
    • 한국식품영양학회지
    • /
    • 제27권6호
    • /
    • pp.1141-1146
    • /
    • 2014
  • The purpose of this study is to investigate the effects of arabinoxylan rice bran and endurance exercise training on TLR4 mediated protein expression in LPS-treated rats. The results showed that TLR4 as an important protein in the inflammatory response against lipopolysaccharide was shown to be significantly lower in both arabinoxylan supplement with exercise group and exercise group, thus the arabinoxylan rice bran had a higher inhibitory activity than arabinoxylan supplement group. However, $NF-{\kappa}B$ and MyD88 protein expression was not changed in arabinoxylan supplement with exercise training group, whereas $NF-{\kappa}B$ significantly decreased in 4 weeks of exercise training group. These results suggest that the supplement of arabinoxylan rice bran with exercise is likely to contribute to inflammation response and the arabinoxylan rice bran can be used as a possible safe alternative to the immunotherapeutic intervention.

향부자팔물탕(香附子八物湯)이 구속(拘束)스트레스 흰쥐의 항(抗)스트레스와 면역반응(免疫反應)에 미치는 영향(影響) (The Experimental Study on the Effects of Hyangbujapalmultang on Anti-stress and Immune Response in Immobilization Stressed Rats)

  • 이승기;김종우;황의완
    • 동의신경정신과학회지
    • /
    • 제8권1호
    • /
    • pp.81-93
    • /
    • 1997
  • In order to investigate the anti-stress effect of Hyangbujapalmultnag in immobilization stress rats, the change of body weight, and, the humoral and cellular immune response were measured.The following results were obtained.1. The decrease of the body weight was significantly inhibited in test group, comparing with the control group.2 In the plaque fomation test, the number of the plaque in the control group was decreased but, the decreased in test group was significantly inhibited, comparing with the control group.3. In the hemagglutination titer, the control group was decreased on the serum antibody titer, but, the decreased in test group was significantly inhibited, comparing with the control group.4. In the footpad swelling response, the differences between the control and test group were not shown.

  • PDF

Influence of Daily Water Temperature Changes on Chemiluminescent Response of Phagocytes and Mortality in Cultured Gray Mullet (Mugil cephalus L.)

  • Kim Ki Hong;Hwang Yoon Jung;Kwon Se Ryun;Huh Sung-Hoi
    • Fisheries and Aquatic Sciences
    • /
    • 제3권2호
    • /
    • pp.78-82
    • /
    • 2000
  • The influence of daily water temperature changes on chemiluminescent (CL) response of phagocytes, plasma glucose level and mortality in cultured gray mullet (Mugil cephalus) was investigated. Among three experimental temperature groups, the fish in group I and group II were maintained constantly at $27^{\circ}C$ and $29^{\circ}C$, respectively, and those in group III were suffered daily elevation of water temperature from $27^{\circ}C$ to $29^{\circ}C$ for 5 hours, then restored again to $27^{\circ}C$. After 1 week of maintaining at each experimental tank, the fish in group III showed significantly lower CL peak value (p < 0.01) and higher plasma glucose levels (p < 0.05) than those in group I and group II. The cumulative mortality of group III was $86.9\%$ within 3 days after being subjected to acute handling stress. On the other hand, the cumulative mortalities of group I and group II were $12.5\%$ and $19.2\%$, respectively. In conclusion, gray mullet farms, especially, in the vicinity of thermoelectric power plants should avoid stressing the fish during periods of high water temperature.

  • PDF

Acid etching of glass-infiltrated zirconia and its biological response

  • Vu, Van Thi;Oh, Gye-Jeong;Yun, Kwi-Dug;Lim, Hyun-Pil;Kim, Ji-Won;Nguyen, Thao Phuong Thi;Park, Sang-Won
    • The Journal of Advanced Prosthodontics
    • /
    • 제9권2호
    • /
    • pp.104-109
    • /
    • 2017
  • PURPOSE. The purpose of this study was to evaluate the influence of acid etching treatment on surface characteristics and biological response of glass-infiltrated zirconia. MATERIALS AND METHODS. A hundred zirconia specimens were divided into four groups depending on surface treatments: untreated zirconia (group Z); acid-etched zirconia (group ZE); glass-infiltrated zirconia (group ZG); and glass-infiltrated and acid-etched zirconia (group ZGE). Surface roughness, surface topography, surface morphology, and Vickers hardness of specimens were evaluated. For biological response test, MC3T3-E1 cell attachment and proliferation on surface of the specimens were examined. The data were statistically analyzed using one-way ANOVA and Tukey's HSD test at a significance level of 0.05. RESULTS. Group ZGE showed the highest surface roughness ($Ra=1.54{\mu}m$) compared with other groups (P < .05). Meanwhile, the hardness of group Z was significantly higher than those of other groups (P < .05). Cell attachment and cell proliferation were significantly higher in group ZGE (P < .05). CONCLUSION. We concluded that effective surface roughness on zirconia could be made by acid etching treatment after glass infiltration. This surface showed significantly enhanced osteoblast cell response.

태극권 수련이 간호대학생의 체력, 스트레스반응, 자아탄력성에 미치는 효과 (The Effects of a Tai Chi Training Program on Physical Fitness, Stress Response and Ego-resilience in Nursing Students)

  • 손정태;이진주
    • 근관절건강학회지
    • /
    • 제24권3호
    • /
    • pp.217-226
    • /
    • 2017
  • Purpose: The aim of this study was to identify the effects of Tai Chi training program on physical fitness, stress response and ego-resiliency in nursing students. Methods: 28 nursing students of D metropolitan city participated in non-equivalent control group pre- and post-test group test in quasi experimental design with written consent. Fourteen participants in the control group who did usual activities and 14 experimental participants who promised to participate 24 Tai Chi training sessions for 12 weeks. Both groups completed pre- and post-test measurement for physical fitness, a questionnaire regarding their stress response and ego-resiliency. Each 60-minute Tai Chi session was consisted of 5-minute warm up, 10-minute meditation, 40-minute Tai Chi, and 5-minute finishing exercise. Results: After 12 weeks, participants in the Tai Chi group reported significantly higher score in muscle endurance (t=3.77, p=.001), leg muscular strength (t=2.14, p=.042), and balance (t=2.12, p=.044) compared to the control group. The Tai Chi group recorded significantly lower score than the control group on stress response (t=2.75, p=.011). Conclusion: The findings highlight the importance of Tai Chi for a reduction in stress response and promotion in physical fitness in nursing students. Applying Tai Chi training to nursing program will help nursing students to have better academic performance.

복합(複合)레진과 세균(細菌)이 치수반응(齒髓反應)에 미치는 영향(影響)에 관(關)한 실험적(實驗的) 연구(硏究) (AN EXPERIMENTAL STUDY ON THE EFFECT OF COMPOSITE RESIN AND BACTERIA TO PULP RESPONSE)

  • 조성식;김영해
    • Restorative Dentistry and Endodontics
    • /
    • 제13권1호
    • /
    • pp.53-67
    • /
    • 1988
  • An investigation was carried out to compare the pulp responses against a few type of composite and streptococcus mutans contamination under the zinc oxide eugenol cement, and also confirmed pulpal responses of various composites with or without base. Seventy eight teeth from 6 dogs were employed and divided into 6 groups. Class V cavities were prepared on each tooth routinely with low speed dental engine. Paper disc about 0.3mm thick was immersed in the BHI broth in which streptococcus mutans had been enriched and the disc was inserted on the cavity floor prior to filling. Scotch bond puls Silux as Bis-GMA system composite resin and Helimolar as urethane system composite resin were adopted. Control group: Zinc-Oxide Eugenol cement filling Experimental groups: Group 1. Scotch bond + Silux filling with Dycal base Group 2. Heliomolar filling with Dycal base Group 3. Scotch bond + Silux filling without base Group 4. Heliomolar filling without base Group 5. Streptococcus mutans application. All cavities were sealed with thick ZOE cement to avoid marginal leakage. Postoperative intervals of 1, 2, 3, 4, 5 and 6 weeks teeth were carefully extracted, processed and stained with Hematoxylin and Eosin. The results were as follows: 1. S. mutans application group and composites without any base showed more severe pupal response than control group and dyca based groups. 2. The experimental group of S. mutans application showed severe response in the early stage compared to the two groups of composite resin without base, but no significant difference was found following periods. 3. The difference of pulpal response is not significant between Bis-GMA system and urethane system. 4. Streptococcus mutans application group and composites without base groups showed the evidence of histologic recovery at the six week cases and the large amount of reparative dentin was the prominent feature. 5. Pulp responses against every material were inclined to normal according to the time elapsed.

  • PDF

생지황(生地黃) 건지황(乾地黃) 숙지황(熟地黃)이 세포성(細胞性) 면역반응(免疫反應) 및 체액성면역반응(體液性免疫反應)에 미치는 영향(影響) (An Experimental Study on the Effects of Row, Dried and Steamed Roots of Rehmanniae glutinosa on cell-mediated and Humoral Immune Response in Mice)

  • 황영명
    • 사상체질의학회지
    • /
    • 제1권1호
    • /
    • pp.139-151
    • /
    • 1989
  • In order to investigate the effects of Raw, Dried and Steamed Roots of Rehmanniae Radix (R.R.: from Wonju province, Korea) on cell-mediated arid humoral immune response, the author performed this experimental study. Delayed type hypersensitivity (DTH) and rosette forming cells (RFC) for cell-mediated immune response, hemagglutinin (HA) titers, hemolysin (HL) titers were maeasured in ICR mice. The results were summarized as follows: 1) DTH was increased with the order of Steamed Roots of R.R., Raw Roots of R.R., Dried Roots of R.R.-treated group, as compared with the control group, with statistical significance. 2) RFC were increased with the order of Raw Roots of R.R., Steamed Roots of R.R., Dried Roots of R.R.-treated group, as compared with the control group, with statistical significance. 5) HA titers were increased with the order of Steamed Roots of R.R., Row Roots of R.R., Dried Roots of R.R.treated group, as compared with the control group, with statistical significance. 4) HL. titers were increased with the order of Raw Roots of R.R., Steamed Roots of R.R., Dried Roots of R.R.-treated group, as compared with the control group, with statistical significance. Through in the experimental study in ICR mice, these findings suggest that all of the treated group was increased in cell-mediated immune reaponse, Raw, Steamed Roots of R.R. were increased more as compared with the Dried Roots of R.R., and all of the treated group was increased in humoral immune response, Raw, Steamed Roots of R.R. were increased more as compared with the dried Roots of R.R.

  • PDF

사위별 가입렌즈에 따른 자극 AC/A비와 반응 AC/A비의 비교 (Comparison between Stimulus and Response AC/A Ratios for Each Phoria with Additional Spherical Power)

  • 이세희;유동식;손정식;곽호원
    • 한국안광학회지
    • /
    • 제19권3호
    • /
    • pp.345-351
    • /
    • 2014
  • 목적: 각 사위 그룹에서 가입렌즈에 따른 조절반응량과 근거리 수평사위도의 변화를 측정하여 자극 AC/A비와 반응 AC/A비를 조사하였다. 이에 자극 AC/A비와 반응 AC/A비를 비교 분석하여 임상에서의 양안시 검사 및 처방시에 유용한 자료로 제시하고자 한다. 방법: 평균 만 $20.89{\pm}1.92$세, 81명을 대상으로 주시거리 40 cm에서 개방형 자동굴절계(Nvision-K 5001, Shin nippon)와 수정된 토링톤 시표(MIM card; Muscle Imbalance Measure card, Bernell)를 이용하여 양안시 상태에서 조절반응량과 근거리 수평사위도를 측정하였다. 그리고 측정된 값을 토대로 자극 AC/A비와 반응 AC/A비를 경사 AC/A법으로 계산하였다. 결과: 주시거리 40 cm에서 조절반응량은 외사위 그룹이 $1.92{\pm}0.26$ D로 가장 크고, 정위 그룹 $1.72{\pm}0.26$ D, 내사위 그룹 $1.62{\pm}0.42$ D 순으로 작아졌고, 근거리 수평사위도의 변화폭은 내사위 그룹이 $23.24{\Delta}$로 가장 크고, 정위 그룹 $19.76{\Delta}$, 외사위 그룹 $15.14{\Delta}$ 순으로 작게 나타났다. 가입렌즈에 따른 자극 AC/A비와 반응 AC/A비의 차이는 외사위 그룹에서는 -2.00 D 렌즈를 가입하였을 때, $1.72{\Delta}/D$로 가장 컸고 내사위 그룹에서는 +1.00 D 렌즈를 가입하였을 때 $3.43{\Delta}/D$로 가장 크게 나타났다. 외사위 그룹에서 -2.00 D, -1.00 D 렌즈를 가입하였을 때, 내사위 그룹에서는 +3.00 D, +2.00 D, +1.00 D, -1.00 D 렌즈를 가입하였을 때 각각 통계적으로 유의한 차이를 보였다. 결론: 자극 AC/A비와 반응 AC/A비를 비교하였을 때, 외사위 그룹에서는 (-) 렌즈를 가입하였을 때의 차이가 더 크고, 내사위 그룹에서는 (+) 렌즈를 가입하였을 때의 차이가 더 크게 나타났다. 또한 내사위 그룹의 자극 AC/A비와 반응 AC/A비의 차이가 외사위 그룹의 차이보다 더 크게 나타났다.

아기마사지가 미숙아의 신체성장과 스트레스 반응에 미치는 영향 (Effects of Infant Massage on Physical Growth and Stress Response in Preterm Babies)

  • 정남연;송영신
    • Child Health Nursing Research
    • /
    • 제15권1호
    • /
    • pp.71-80
    • /
    • 2009
  • Purpose: This study was done to investigate the effects of an infant massage on physical growth and stress response in preterm babies. Method: A nonequivalent control group with pre-posttest design was used with 56 preterm babies in the NICU of E medical center at Daejeon. Data were collected from July 2004 to May 2005. The intervention was given for 15 minutes, once a day for 7 days. Physical growth was measured by weight, length, head circumference, and stress response was measured by serum cortisol level. Mean, %, paired-test, t-test with the SPSS/W in 16.0 program were used to analyze the data. Results: After the intervention, physical growth variables (weight, length, head circumference) in experimental group were higher than that of the control group. Also, the serum cortisol level in the experimental group was lower than that of the control group. But none of these results were not statistically significant. Conclusion: The results of this study suggest that a 7-day intervention period may not be long enough to confirm the effects of infant massage on physical growth and stress reaction. Therefore it is suggested that a longer period of infant massage should be tested to determine if it is effective in improving the physical growth and stress reduction in preterm babies.

  • PDF

주자독서환의 뇌기능 활성 및 신경세포 보호효과 (The Effects of Jujadokseo-hwan on the Activation of Brain and Neuroprotactive Effects)

  • 이유경;채중원
    • 대한한방소아과학회지
    • /
    • 제23권3호
    • /
    • pp.241-262
    • /
    • 2009
  • Objectives This study is designed to investigate the effects of Jujadokseo-hwan on the brain ability and inducing oxidative stresses. Methods We measured the changes of regional cerebral blood flow and mean arterial blood pressure. Then we analyzed histological examination, immunohistochemistric response and anti-oxidant activity of Jujadokseo-hwan. Results 1. Treatment of Jujadokseo-hwan significantly increased regional cerebral blood flow but decreased mean arterial blood pressure. 2. Treatment of Jujadokseo-hwan-induced increase of regional cerebral blood flow was significantly inhibited by pretreatment with indomethacin (1 mg/kg, i.p.), an inhibitor of cyclooxygenase. 3. In histological examination through TTC stain, group I was no change, but group II showed that discolored in the most cortical part. Group III showed that decreased discolor in the cortical part. 4. In immunohistochemistric response of BDNF, group II showed that lower response effect. Group III showed that increase response effect. 5. Treatment of Jujadokseo-hwan increased proliferation rates of Glial cell effectively 6. Treatment of Jujadokseo-hwan accelerated proliferation rates of C6 cells in vitro. In addition, protective effects on cell death induced by paraquat, rotenone and hydrogen peroxide. In addition, activity of SOD were increased by treatment with Jujadokseo-hwan. Conclusions In conclusion, Jujadokseo-hwan can improve of the brain ability, learning ability, memory ability and induce ischemic brain injuries.

  • PDF