• Food Science and Biotechnology
• /
• 제14권6호
• /
• pp.732-737
• /
• 2005

The combinational effect of gamma irradiation and moist heating on the trypsin inhibitor activity (TIA) in soaked and dried soybeans was evaluated by measuring the inhibition using N-benzoyl-DL-arginine-p-nitroanilide (BAPNA) as substrate. Gamma irradiation significantly decreased the TIA level in soybean at doses above 5 kGy, and the $ID_{50}$ (the gamma irradiation dose required to reach 50% inhibition) value for TIA was 13.53 kGy. Soaking prior to gamma irradiation significantly lowered the $ID_{50}$ to 8.44 kGy, and the soaking process enhanced the efficiency to inactivate TIA by as much as 48%. When soaking prior to gamma irradiation was followed by subsequent mild heating ($60^{\circ}C$) process, the $IT_{50}$ (heating time required to reach the 50% inhibition of TIA) value at even 1 kGy (5.28 min) was greatly reduced by over 50% compared to the level for the no-soaking process. In addition, the activation energy of soaking prior to gamma irradiation at 1 kGy was 2.45 kcal/mole, which was also about 50% lower than the 5.10 kcal/mole of dried soybean gamma-irradiated. Based on these results, soaking prior to gamma irradiation is an effective method for TIA inhibition. Furthermore, a combination of two or more processing methods such as soaking, heating and gamma irradiation is much more effective than any single processing method.

• Journal of Preventive Medicine and Public Health
• /
• 제35권2호
• /
• pp.169-174
• /
• 2002

Objective : To investigate gamma-Glutamyltransferase (${\gamma}-GTP$) and its related factors in male industrial workers. Method : Five hundred and tony male workers without heart disease, diabetes mellitus, renal disease, hepatitis, and other liver diseases were surveyed in October 1998. Blood samples were collected to test for ${\gamma}-GTP$, total-cholesterol and fasting blood glucose. A self-administered questionnaire survey on life style was also done. Results : The total geometric mean value of ${\gamma}-GTP$ was 30.6 U/L. According to a univariate analysis: age, BMI(body mass index, $kg/m^2$), alcohol consumption, current smoking, stress, diastolic blood pressure, and blood total cholesterol were significantly associated with ${\gamma}-GTP$(p<0.05). From a multiple regression analysis: BMI, alcohol consumption, current smoking, diastolic blood pressure and total-cholesterol were significantly related to ${\gamma}-GTP$(p<0.05). Coffee consumption was negatively related to ${\gamma}-GTP$, but not significantly. Conclusion : We recommend that a change in health behavior (i.e. reducing alcohol intake, controlling BMI and not smoking) is necessary to decrease ${\gamma}-GTP$ in male workers.

• Food Science and Biotechnology
• /
• 제17권6호
• /
• pp.1146-1150
• /
• 2008

Peroxisome proliferator-activated receptor-gamma ($PPAR_{\gamma}$), a member of the nuclear receptor of ligand-activated transcription factors, plays a key role in lipid and glucose metabolism or adipocytes differentiation. A lignan compound was isolated from mace (the aril of Myristica fragrans Houtt.) as a $PPAR_{\gamma}$ ligand, which was identified as fragrin A or 2-(4-allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-propane. To ascertain whether fragrin A has $PPAR_{\gamma}$ ligand-binding activity, it was performed that GAL-4/$PPAR_{\gamma}$ transactivation assay. $PPAR_{\gamma}$ ligand-binding activity of fragrin A increased 4.7, 6.6, and 7.3-fold at 3, 5, and $10{\mu}M$, respectively, when compared with a vehicle control. Fragrin A also enhanced adipocytes differentiation and increased the expression of $PPAR_{\gamma}$ target genes such as adipocytes fatty acid-binding protein (aP2), lipoprotein lipase (LPL), and phosphoenol pyruvate carboxykinase (PEPCK). Furthermore, it significantly increased the expression level of glucose transporter 4 (GLUT4). These results indicate that fragrin A can be developed as a $PPAR_{\gamma}$ agonist for the improvement of insulin resistance associated with type 2 diabetes.

• Kyungpook Mathematical Journal
• /
• 제45권2호
• /
• pp.241-247
• /
• 2005

Let ${\gamma}{\equiv}\left{{\gamma}_{ij}\right}(0{\leq}i+j{\leq}2n)$ be a collection of complex numbers with ${\gamma}_{00}>0$ and ${\gamma}_{ji}={\bar{\gamma}}_{ij}$. The truncated complex moment problem for ${\gamma}$ entails finding a positive Borel measure ${\mu}$ supported in the complex plane ${\mathbb{C}}$ such that ${\gamma}_{ij}={\int}{\bar{z}}^{i}z^jd{\mu}(z)(0{\leq}i+j{\leq}2n)$. We solve this truncated moment problem with data in a circle and discuss the behavior of data in an extended moment matrix.

• Toxicological Research
• /
• 제14권3호
• /
• pp.371-377
• /
• 1998

We have cloned a soluble type human folate receptor(hFR type${\gamma}$) from human thymus cDNA library using the PCR amplification technique. To examine whether hFR type${\gamma}$ has a folate transport activity, CHO cells were transfected with the pcDNAhFR${\gamma}$ expression plasmid, and the stable cell line CHO/hFR${\gamma}$ expressing a high level of the hFR type${\gamma}$ was identified by northern and western blot analysis. The CHO/hFR${\gamma}$ cells produced a [$H^3$]folic acid binding protein in the culture medium. However, we couldn't detect any cell surface [$H^3$] folic acid binding and transport activities. The growth of the CHO/hFR${\gamma}$ cells was more rapidly inhibited than the wild type CHO cells in the low concentration folic acid media. These observations indicate that although soluble type human folate receptor can bind [$H^3$]folate, it does not involve in folate transport.

• Korean Journal of Mathematics
• /
• 제17권2호
• /
• pp.189-196
• /
• 2009

Let D be an integral domain, and let U be a group of units of D. Let $D^*=D-\{0\}$ and ${\Gamma}=D^*/U$ be the commutative cancellative semigroup under aU+bU=abU. We prove that $Cl(D)=Cl({\Gamma})$ and that D is a PvMD (resp., GCD-domain, Mori domain, Krull domain, factorial domain) if and only if ${\Gamma}$ is a PvMS(resp., GCD-semigroup, Mori semigroup, Krull semigroup, factorial semigroup). Let U=U(D) be the group of units of D. We also show that if D is integrally closed, then $D[{\Gamma}]$, the semigroup ring of ${\Gamma}$ over D, is an integrally closed domain with $Cl(D[{\Gamma}])=Cl(D){\oplus}Cl(D)$; hence D is a PvMD (resp., GCD-domain, Krull domain, factorial domain) if and only if $D[{\Gamma}]$ is.

• Applied Biological Chemistry
• /
• 제36권1호
• /
• pp.29-32
• /
• 1993

Latex(Hevea Brasiliensis)로부터 3종의 ${\alpha}-,\;{\gamma}-,\;{\delta}-tocotrienol$을 각각 분리하고, oil 상태의 각 성분을 얻었다. Tocotrienol을 분리하기 위하여, latex에서 추출한 조지방 성분의 비비누화분획으로 부터 semipreparative HPLC에 의한 분리방법을 사용하여 tocotrienol을 분리하였다. 이와 같은 분리방법을 이용하였을 때 latex에 함유된 tocotrienol의 함량은 약 400ppm이었으며, 순도는 ${\alpha}-,\;{\gamma}-,\;{\delta}-tocotrienol$ 각각 98.3, 99.3, 96.2%로 나타났다.

• 대한수학회지
• /
• 제34권2호
• /
• pp.337-344
• /
• 1997

In this paper, we study the isomorphism problem of Cayley permutation graphs. We obtain a necessary and sufficient condition that two Cayley permutation graphs are isomrphic by a direction-preserving and color-preserving (positive/negative) natural isomorphism. The result says that if a graph G is the Cayley graph for a group $\Gamma$ then the number of direction-preserving and color-preserving positive natural isomorphism classes of Cayley permutation graphs of G is the number of double cosets of $\Gamma^\ell$ in $S_\Gamma$, where $S_\Gamma$ is the group of permutations on the elements of $\Gamma and \Gamma^\ell$ is the group of left translations by the elements of $\Gamma$. We obtain the number of the isomorphism classes by counting the double cosets.

• Kyungpook Mathematical Journal
• /
• 제55권4호
• /
• pp.827-835
• /
• 2015

Let U be a ${\sigma}$-square closed Lie ideal of a 2-torsion free ${\sigma}$-prime ${\Gamma}$-ring M. Let $d{\neq}1$ be an automorphism of M such that $[u,d(u)]_{\alpha}{\in}Z(M)$ on U, $d{\sigma}={\sigma}d$ on U, and there exists $u_0$ in $Sa_{\sigma}(M)$ with $M{\Gamma}u_0{\subseteq}U$. Then, $U{\subseteq}Z(M)$. By applying this result, we generalize the results of Oukhtite and Salhi respect to ${\Gamma}$-rings. Finally, for a non-zero derivation of a 2-torsion free ${\sigma}$-prime $\Gamma$-ring, we obtain suitable conditions under which the $\Gamma$-ring must be commutative.

• 한국수학교육학회지시리즈B:순수및응용수학
• /
• 제21권4호
• /
• pp.237-246
• /
• 2014

Let M be a prime ${\Gamma}$-ring and let d be a derivation of M. If there exists a fixed integer n such that $(d(x){\alpha})^nd(x)=0$ for all $x{\in}M$ and ${\alpha}{\in}{\Gamma}$, then we prove that d(x) = 0 for all $x{\in}M$. This result can be extended to semiprime ${\Gamma}$-rings.